iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ggo-045505

UUCD1 version

UUC-GoG-00778

Ensembl Protein ID

ENSGGOP00000012642.2

UniProt Accession

G3RXG7; G3RXG7_GORGO

Protein Name

Uncharacterized protein

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000012957.2	ENSGGOT00000013006.2	ENSGGOP00000012642.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.59	0.00e+00	897.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MTSFSTSAQC STSDSACRIS PGQINQVRPK LPLLKILHAA GAQGEMFTVK EVMHYLGQYI 60
MVKQLYDQQE QHMVYCGGDL LGELLGRQSF SVKDPSPLYD MLRKNLVTLA TATTDAAQTL 120

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Nucleotide Sequence
(Fasta)

GTGTGGGAGG CCGGAAGTTG CGGCTTCATT ACTCGCCATT TCAAAATGCT GCCGAGGCCC 60
TAGGACCTGT GACTGCCACC CCTCCCCCCA CCCGGGCTCG GCGGGGGAGC GACTCATGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome

Interpro

IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

KEGG

ggo:101133824

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	92.68	0.00e+00	802.00
IUUC-Apl-003800	Anas platyrhynchos	60.12	1.00e-153	535.00
IUUC-Aca-004608	Anolis carolinensis	57.23	4.00e-137	481.00
IUUC-Ame-010869	Astyanax mexicanus	46.53	8.00e-105	374.00
IUUC-Bta-013287	Bos taurus	89.82	0.00e+00	855.00
IUUC-Cja-019305	Callithrix jacchus	94.90	0.00e+00	852.00
IUUC-Cfa-020393	Canis familiaris	93.50	0.00e+00	826.00
IUUC-Cpo-022166	Cavia porcellus	89.27	0.00e+00	750.00
IUUC-Csa-023654	Chlorocebus sabaeus	97.96	0.00e+00	852.00
IUUC-Cho-024403	Choloepus hoffmanni	90.26	1.00e-128	452.00
IUUC-Cin-025448	Ciona intestinalis	27.60	7.00e-21	94.00
IUUC-Cgl-026403	Colletotrichum gloeosporioides	34.88	3.60e-01	31.20
IUUC-Dre-027754	Danio rerio	49.01	9.00e-116	410.00
IUUC-Dno-029630	Dasypus novemcinctus	89.23	0.00e+00	820.00
IUUC-Dor-031064	Dipodomys ordii	69.25	0.00e+00	647.00
IUUC-Ete-032901	Echinops telfairi	79.07	0.00e+00	756.00
IUUC-Eca-034234	Equus caballus	94.50	0.00e+00	902.00
IUUC-Eeu-035015	Erinaceus europaeus	64.84	3.00e-157	548.00
IUUC-Fca-036587	Felis catus	93.08	0.00e+00	837.00
IUUC-Fal-036906	Ficedula albicollis	53.77	6.00e-137	480.00
IUUC-Gmo-038646	Gadus morhua	43.70	1.00e-95	343.00
IUUC-Gga-040124	Gallus gallus	59.12	2.00e-113	401.00
IUUC-Gac-042397	Gasterosteus aculeatus	45.82	3.00e-106	378.00
IUUC-Hsa-046950	Homo sapiens	99.59	0.00e+00	897.00
IUUC-Itr-048886	Ictidomys tridecemlineatus	91.04	0.00e+00	828.00
IUUC-Lch-050141	Latimeria chalumnae	54.29	9.00e-121	426.00
IUUC-Loc-051921	Lepisosteus oculatus	49.90	6.00e-114	404.00
IUUC-Laf-054281	Loxodonta africana	86.97	0.00e+00	778.00
IUUC-Mcc-055462	Macaca mulatta	94.50	0.00e+00	802.00
IUUC-Meu-056294	Macropus eugenii	70.86	8.00e-145	506.00
IUUC-Mga-059924	Meleagris gallopavo	60.24	9.00e-165	573.00
IUUC-Mmr-061428	Microcebus murinus	92.46	0.00e+00	866.00
IUUC-Mdo-062643	Monodelphis domestica	75.65	0.00e+00	716.00
IUUC-Mmu-063229	Mus musculus	83.71	0.00e+00	766.00
IUUC-Mpu-065782	Mustela putorius furo	91.08	0.00e+00	812.00
IUUC-Mlu-068105	Myotis lucifugus	81.10	0.00e+00	766.00
IUUC-Nle-069549	Nomascus leucogenys	99.59	0.00e+00	896.00
IUUC-Opr-070568	Ochotona princeps	90.11	0.00e+00	771.00
IUUC-Ont-072276	Oreochromis niloticus	47.00	4.00e-116	411.00
IUUC-Oan-072787	Ornithorhynchus anatinus	73.08	0.00e+00	646.00
IUUC-Ocu-074912	Oryctolagus cuniculus	89.82	0.00e+00	815.00
IUUC-Ola-087037	Oryzias latipes	45.13	2.00e-96	346.00
IUUC-Oga-088953	Otolemur garnettii	89.09	0.00e+00	813.00
IUUC-Oar-089202	Ovis aries	89.82	0.00e+00	858.00
IUUC-Ptr-090964	Pan troglodytes	99.59	0.00e+00	897.00
IUUC-Pan-091975	Papio anubis	98.16	0.00e+00	871.00
IUUC-Psi-093558	Pelodiscus sinensis	60.69	1.00e-156	546.00
IUUC-Pma-094500	Petromyzon marinus	30.93	2.00e-21	95.10
IUUC-Pfo-096454	Poecilia formosa	47.05	3.00e-109	388.00
IUUC-Pab-098123	Pongo abelii	98.98	0.00e+00	894.00
IUUC-Pca-101112	Procavia capensis	78.25	0.00e+00	717.00
IUUC-Pva-103098	Pteropus vampyrus	82.28	0.00e+00	766.00
IUUC-Rno-105930	Rattus norvegicus	83.74	0.00e+00	736.00
IUUC-Sha-107512	Sarcophilus harrisii	73.78	0.00e+00	638.00
IUUC-Sar-113584	Sorex araneus	82.69	0.00e+00	716.00
IUUC-Tgu-116766	Taeniopygia guttata	56.70	2.00e-100	358.00
IUUC-Tru-117829	Takifugu rubripes	46.91	9.00e-112	397.00
IUUC-Tsy-119268	Tarsius syrichta	78.21	0.00e+00	677.00
IUUC-Tni-120204	Tetraodon nigroviridis	45.90	7.00e-109	387.00
IUUC-Tbe-127840	Tupaia belangeri	85.71	3.00e-127	448.00
IUUC-Ttr-128863	Tursiops truncatus	89.61	0.00e+00	826.00
IUUC-Vpa-130718	Vicugna pacos	92.47	0.00e+00	802.00
IUUC-Xtr-132320	Xenopus tropicalis	47.39	3.00e-89	321.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence