iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Itr-048886

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTP01062140

Gene Name

MDM4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSTOG00000004184.2	ENSSTOT00000004186.2	ENSSTOP00000003760.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.04	0.00e+00	830.00	IUUC-Hsa-046950

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Ictidomys tridecemlineatus

Protein Sequence
(Fasta)

MTSYSTSAQC STSDSACRIS PERVNKVRPK LPLLKILQAA GAEGEMFTVK EVMHYLGQYI 60
MVKQLYDQQE QHMVYCGGDL LGELLGRQSF SVKDPSPLYD MLRKNLVTLS TATTDAAQTL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACATCAT ATTCCACCTC TGCCCAGTGT TCAACATCTG ATAGTGCTTG CAGGATCTCT 60
CCAGAACGAG TCAATAAGGT GAGTCATTAT TGGGCATTCC TGTTTTTCTT TAAATTTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR015458--MDM4
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0008283--P:cell proliferation
GO:0071456--P:cellular response to hypoxia
GO:0030330--P:DNA damage response, signal transduction by p53 class mediator
GO:0045023--P:G0 to G1 transition
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0042177--P:negative regulation of protein catabolic process
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0006461--P:protein complex assembly
GO:0050821--P:protein stabilization

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001467	Ailuropoda melanoleuca	89.23	0.00e+00	788.00
IUUC-Apl-003800	Anas platyrhynchos	60.37	1.00e-154	539.00
IUUC-Aca-004608	Anolis carolinensis	58.16	2.00e-145	508.00
IUUC-Ame-010869	Astyanax mexicanus	47.26	4.00e-109	388.00
IUUC-Bta-013287	Bos taurus	87.98	0.00e+00	848.00
IUUC-Cja-019305	Callithrix jacchus	89.00	0.00e+00	802.00
IUUC-Cfa-020393	Canis familiaris	90.65	0.00e+00	816.00
IUUC-Cpo-022166	Cavia porcellus	89.27	0.00e+00	763.00
IUUC-Csa-023654	Chlorocebus sabaeus	90.84	0.00e+00	792.00
IUUC-Cho-024403	Choloepus hoffmanni	88.39	6.00e-126	443.00
IUUC-Dre-027754	Danio rerio	47.73	2.00e-119	422.00
IUUC-Dno-029630	Dasypus novemcinctus	87.20	0.00e+00	832.00
IUUC-Dor-031064	Dipodomys ordii	69.45	0.00e+00	669.00
IUUC-Ete-032901	Echinops telfairi	77.24	0.00e+00	746.00
IUUC-Eca-034234	Equus caballus	91.65	0.00e+00	916.00
IUUC-Eeu-035015	Erinaceus europaeus	64.23	1.00e-162	565.00
IUUC-Fca-036587	Felis catus	90.63	0.00e+00	830.00
IUUC-Fal-036906	Ficedula albicollis	52.13	3.00e-134	471.00
IUUC-Gmo-038646	Gadus morhua	44.18	4.00e-96	345.00
IUUC-Gga-040124	Gallus gallus	58.06	1.00e-113	402.00
IUUC-Gac-042397	Gasterosteus aculeatus	46.03	5.00e-109	387.00
IUUC-Ggo-045505	Gorilla gorilla	91.04	0.00e+00	815.00
IUUC-Hsa-046950	Homo sapiens	91.04	0.00e+00	816.00
IUUC-Lch-050141	Latimeria chalumnae	53.68	2.00e-124	438.00
IUUC-Loc-051921	Lepisosteus oculatus	49.50	1.00e-116	413.00
IUUC-Laf-054281	Loxodonta africana	86.15	0.00e+00	778.00
IUUC-Mcc-055462	Macaca mulatta	87.60	0.00e+00	744.00
IUUC-Meu-056294	Macropus eugenii	72.80	4.00e-148	517.00
IUUC-Mga-059924	Meleagris gallopavo	59.03	5.00e-165	573.00
IUUC-Mmr-061428	Microcebus murinus	89.41	0.00e+00	852.00
IUUC-Mdo-062643	Monodelphis domestica	75.86	0.00e+00	723.00
IUUC-Mmu-063229	Mus musculus	81.26	0.00e+00	773.00
IUUC-Mpu-065782	Mustela putorius furo	88.84	0.00e+00	803.00
IUUC-Mlu-068105	Myotis lucifugus	79.27	0.00e+00	755.00
IUUC-Nle-069549	Nomascus leucogenys	91.24	0.00e+00	818.00
IUUC-Opr-070568	Ochotona princeps	88.60	0.00e+00	768.00
IUUC-Ont-072276	Oreochromis niloticus	46.56	1.00e-116	412.00
IUUC-Oan-072787	Ornithorhynchus anatinus	72.22	0.00e+00	651.00
IUUC-Ocu-074912	Oryctolagus cuniculus	88.59	0.00e+00	814.00
IUUC-Ola-087037	Oryzias latipes	45.88	6.00e-101	360.00
IUUC-Oga-088953	Otolemur garnettii	85.66	0.00e+00	791.00
IUUC-Oar-089202	Ovis aries	88.39	0.00e+00	855.00
IUUC-Ptr-090964	Pan troglodytes	91.04	0.00e+00	816.00
IUUC-Pan-091975	Papio anubis	91.04	0.00e+00	811.00
IUUC-Psi-093558	Pelodiscus sinensis	62.53	5.00e-163	566.00
IUUC-Pfo-096454	Poecilia formosa	48.07	1.00e-114	406.00
IUUC-Pab-098123	Pongo abelii	91.45	0.00e+00	820.00
IUUC-Pca-101112	Procavia capensis	77.44	0.00e+00	716.00
IUUC-Pva-103098	Pteropus vampyrus	79.84	0.00e+00	752.00
IUUC-Rno-105930	Rattus norvegicus	81.71	0.00e+00	749.00
IUUC-Sha-107512	Sarcophilus harrisii	74.19	0.00e+00	647.00
IUUC-Smo-108729	Selaginella moellendorffii	44.44	3.00e-05	43.90
IUUC-Sit-110065	Setaria italica	39.22	1.00e-05	45.10
IUUC-Sar-113584	Sorex araneus	80.24	0.00e+00	709.00
IUUC-Tgu-116766	Taeniopygia guttata	55.76	4.00e-99	353.00
IUUC-Tru-117829	Takifugu rubripes	48.87	3.00e-115	408.00
IUUC-Tsy-119268	Tarsius syrichta	75.97	0.00e+00	663.00
IUUC-Tni-120204	Tetraodon nigroviridis	47.03	1.00e-110	392.00
IUUC-Tbe-127840	Tupaia belangeri	83.82	2.00e-124	438.00
IUUC-Ttr-128863	Tursiops truncatus	88.80	0.00e+00	826.00
IUUC-Vpa-130718	Vicugna pacos	90.11	0.00e+00	796.00
IUUC-Xtr-132320	Xenopus tropicalis	47.05	2.00e-91	328.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence