iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	6.00e-06	26.6	11	79
E3 activity/RING/RING	5.00e-08	33.7	16	61

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwlasggk......tcPvtrqplteedlvPnltlrrli 65
            +e +CpI     r+Pv++ +G+ + r ++ ++ ++ g       +cP++++p+++ ++ Pn  l +++
   Q: 11   ADEVNCPICQGTLREPVTIDCGHNFCRGCLTRFCETPGPeseeslSCPLCKEPFRPGSFRPNWQLANVV 79
           57899****************************966666678889*****************9987776 PP

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw...pglknssskefrCPlCr 46
           C+iC+  +++ p++ +CgH f++ Cl ++   pg+   s  + +CPlC+
   Q: 16   CPICQGTLRE-PVTIDCGHNFCRGCLTRFcetPGPE--SEESLSCPLCK 61
           ********99.*******************877777..99********7 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MASAPSVTSL ADEVNCPICQ GTLREPVTID CGHNFCRGCL TRFCETPGPE SEESLSCPLC 60
KEPFRPGSFR PNWQLANVVE NIERLQLAST RGLEVEDACP EHGEKIYFFC EEDEAQLCVV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAGGAAAGA TCTCTTTCAA CAGTGGACTG CAGAGAGAAT ACACACTTAT TTTTATGTTT 60
TTTTTCCTGT GAGCAGCTTC GGGTAGACAG AAAGAGACAG TGAGACCCAG GCCATAGGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005737--C:cytoplasm
GO:0008270--F:zinc ion binding
GO:0030218--P:erythrocyte differentiation
GO:0045087--P:innate immune response
GO:0046597--P:negative regulation of viral entry into host cell

KEGG

rno:294210

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002355	Ailuropoda melanoleuca	82.92	0.00e+00	791.00
IUUC-Bta-012587	Bos taurus	80.53	0.00e+00	774.00
IUUC-Cja-018721	Callithrix jacchus	83.54	0.00e+00	810.00
IUUC-Cfa-020759	Canis familiaris	80.21	0.00e+00	756.00
IUUC-Cpo-022485	Cavia porcellus	69.88	0.00e+00	658.00
IUUC-Csa-023679	Chlorocebus sabaeus	83.75	0.00e+00	811.00
IUUC-Cho-024918	Choloepus hoffmanni	67.50	3.00e-91	327.00
IUUC-Dno-028912	Dasypus novemcinctus	72.92	0.00e+00	721.00
IUUC-Dor-030459	Dipodomys ordii	76.08	0.00e+00	750.00
IUUC-Ete-032226	Echinops telfairi	79.23	4.00e-159	553.00
IUUC-Eca-034379	Equus caballus	81.46	0.00e+00	807.00
IUUC-Eeu-035312	Erinaceus europaeus	76.46	0.00e+00	756.00
IUUC-Fca-036106	Felis catus	77.50	0.00e+00	740.00
IUUC-Ggo-045433	Gorilla gorilla	83.54	0.00e+00	835.00
IUUC-Hsa-046260	Homo sapiens	83.33	0.00e+00	811.00
IUUC-Itr-048465	Ictidomys tridecemlineatus	80.04	0.00e+00	744.00
IUUC-Laf-054405	Loxodonta africana	82.29	0.00e+00	820.00
IUUC-Mcc-055599	Macaca mulatta	83.96	0.00e+00	814.00
IUUC-Meu-056471	Macropus eugenii	62.91	1.00e-118	419.00
IUUC-Mmr-061779	Microcebus murinus	72.38	0.00e+00	684.00
IUUC-Mdo-062384	Monodelphis domestica	72.05	0.00e+00	682.00
IUUC-Mmu-063430	Mus musculus	93.66	0.00e+00	904.00
IUUC-Mpu-066787	Mustela putorius furo	79.38	0.00e+00	756.00
IUUC-Mlu-067590	Myotis lucifugus	71.20	1.00e-118	419.00
IUUC-Nle-069295	Nomascus leucogenys	83.75	0.00e+00	815.00
IUUC-Opr-070615	Ochotona princeps	41.34	8.00e-90	323.00
IUUC-Oan-073329	Ornithorhynchus anatinus	41.05	7.00e-95	341.00
IUUC-Ocu-074896	Oryctolagus cuniculus	84.10	0.00e+00	641.00
IUUC-Oga-088589	Otolemur garnettii	82.29	0.00e+00	787.00
IUUC-Oar-089521	Ovis aries	80.17	0.00e+00	757.00
IUUC-Ptr-090905	Pan troglodytes	82.71	0.00e+00	823.00
IUUC-Pan-092682	Papio anubis	84.17	0.00e+00	788.00
IUUC-Pab-098559	Pongo abelii	83.42	6.00e-177	613.00
IUUC-Pca-100591	Procavia capensis	73.12	0.00e+00	696.00
IUUC-Pva-103067	Pteropus vampyrus	80.83	0.00e+00	765.00
IUUC-Sha-107385	Sarcophilus harrisii	72.60	0.00e+00	723.00
IUUC-Sar-113541	Sorex araneus	82.62	6.00e-149	519.00
IUUC-Ssc-115893	Sus scrofa	81.70	0.00e+00	803.00
IUUC-Tsy-119290	Tarsius syrichta	83.09	1.00e-157	548.00
IUUC-Tbe-127565	Tupaia belangeri	77.63	2.00e-102	366.00
IUUC-Ttr-128456	Tursiops truncatus	80.62	0.00e+00	771.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence