iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
Protein-protein Interaction
IID	iRefIndex	PINA
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.20e-23	80.2	271	301

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclafsd..tllvsGsdDgtikvWDl 30
           H+++v+ ++++   t+l+s +dDg +++W++
   Q: 271  HNCPVWRVCWNMlaTMLISTGDDGCVRLWRM 301
           9*********66679**************97 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MFDVEPIIAD HKDVIHDVVF DYYGRRMATC SSDQTVKIWD EDGQGKWNVT SSWKAHSGSI 60
WRVSWAHPEF GQVVATCSFD RTASVWEEVI GEKVSSTNTP TRRWVRRTTL VDSRTSVTDV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CATTCCGTGA TGCTCGCTGC TCCCGGCATC AGCAGAGGTT TTTTAAAAGT CATAAAAGAA 60
ATTCCCGACG CGACGCCCGC TTTAATCTCA GATAGGCGGC GAGTGCCTGA AAAATCTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0044754--C:autolysosome
GO:0061700--C:GATOR2 complex
GO:0005764--C:lysosome
GO:0005635--C:nuclear envelope
GO:0043234--C:protein complex
GO:0035859--C:Seh1-associated complex
GO:0034198--P:cellular response to amino acid starvation
GO:0007293--P:germarium-derived egg chamber formation
GO:0010507--P:negative regulation of autophagy
GO:0048477--P:oogenesis
GO:0045793--P:positive regulation of cell size
GO:0032008--P:positive regulation of TOR signaling
GO:0051445--P:regulation of meiotic cell cycle
GO:0007346--P:regulation of mitotic cell cycle
GO:1903432--P:regulation of TORC1 signaling

KEGG

dme:Dmel_CG8722

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001926	Ailuropoda melanoleuca	58.88	7.00e-106	376.00
IUUC-Apl-003654	Anas platyrhynchos	55.21	2.00e-88	318.00
IUUC-Aca-004378	Anolis carolinensis	55.56	3.00e-90	323.00
IUUC-Ago-007816	Ashbya gossypii	30.50	5.00e-45	173.00
IUUC-Ame-011945	Astyanax mexicanus	57.23	4.00e-107	380.00
IUUC-Bta-013306	Bos taurus	58.26	3.00e-106	377.00
IUUC-Cel-018235	Caenorhabditis elegans	37.65	2.00e-64	238.00
IUUC-Cja-018849	Callithrix jacchus	57.76	2.00e-105	374.00
IUUC-Cfa-020841	Canis familiaris	58.79	7.00e-103	369.00
IUUC-Cpo-021379	Cavia porcellus	57.63	2.00e-104	371.00
IUUC-Csa-023900	Chlorocebus sabaeus	58.26	9.00e-106	376.00
IUUC-Cho-024660	Choloepus hoffmanni	56.25	1.00e-89	322.00
IUUC-Cin-025471	Ciona intestinalis	45.56	7.00e-85	306.00
IUUC-Csv-026242	Ciona savignyi	54.10	2.00e-75	274.00
IUUC-Dre-028068	Danio rerio	56.00	3.00e-111	394.00
IUUC-Dno-029981	Dasypus novemcinctus	56.17	9.00e-106	376.00
IUUC-Ete-032243	Echinops telfairi	32.62	2.00e-44	171.00
IUUC-Eca-033425	Equus caballus	55.63	6.00e-88	316.00
IUUC-Eeu-035119	Erinaceus europaeus	44.36	5.00e-60	223.00
IUUC-Fca-036520	Felis catus	58.15	6.00e-107	380.00
IUUC-Fal-037234	Ficedula albicollis	55.29	6.00e-90	325.00
IUUC-Gmo-039013	Gadus morhua	55.86	5.00e-106	376.00
IUUC-Gga-041059	Gallus gallus	56.92	1.00e-105	375.00
IUUC-Gac-041337	Gasterosteus aculeatus	56.46	4.00e-107	380.00
IUUC-Ggo-044944	Gorilla gorilla	58.15	3.00e-107	380.00
IUUC-Hsa-046038	Homo sapiens	58.15	3.00e-107	381.00
IUUC-Itr-048858	Ictidomys tridecemlineatus	56.34	1.00e-88	318.00
IUUC-Kpa-049201	Komagataella pastoris	32.50	4.00e-44	171.00
IUUC-Lch-050466	Latimeria chalumnae	50.80	5.00e-101	360.00
IUUC-Loc-052773	Lepisosteus oculatus	49.09	3.00e-100	357.00
IUUC-Laf-053409	Loxodonta africana	58.57	2.00e-106	378.00
IUUC-Meu-055958	Macropus eugenii	49.77	4.00e-58	217.00
IUUC-Mga-059348	Meleagris gallopavo	55.21	7.00e-89	319.00
IUUC-Mmr-060977	Microcebus murinus	63.16	4.00e-86	309.00
IUUC-Mdo-061806	Monodelphis domestica	57.32	2.00e-106	378.00
IUUC-Mmu-064328	Mus musculus	57.54	2.00e-111	394.00
IUUC-Mpu-066873	Mustela putorius furo	58.26	3.00e-105	374.00
IUUC-Mlu-067563	Myotis lucifugus	58.63	2.00e-101	361.00
IUUC-Nle-068977	Nomascus leucogenys	57.62	5.00e-96	343.00
IUUC-Opr-070773	Ochotona princeps	48.40	4.00e-44	171.00
IUUC-Ont-072644	Oreochromis niloticus	56.16	2.00e-106	378.00
IUUC-Oan-073098	Ornithorhynchus anatinus	56.06	1.00e-89	322.00
IUUC-Ocu-073911	Oryctolagus cuniculus	58.15	4.00e-107	380.00
IUUC-Ola-087096	Oryzias latipes	55.56	4.00e-106	377.00
IUUC-Oga-088798	Otolemur garnettii	58.15	1.00e-107	381.00
IUUC-Oar-090298	Ovis aries	56.06	2.00e-89	324.00
IUUC-Ptr-091074	Pan troglodytes	57.85	2.00e-107	381.00
IUUC-Pan-092013	Papio anubis	61.87	3.00e-88	317.00
IUUC-Psi-093508	Pelodiscus sinensis	56.25	1.00e-89	322.00
IUUC-Pma-094288	Petromyzon marinus	59.13	2.00e-72	263.00
IUUC-Pfo-096384	Poecilia formosa	56.76	1.00e-107	382.00
IUUC-Pab-098629	Pongo abelii	58.15	1.00e-107	382.00
IUUC-Pca-100322	Procavia capensis	39.93	8.00e-58	216.00
IUUC-Pva-102861	Pteropus vampyrus	57.94	2.00e-105	375.00
IUUC-Rno-104895	Rattus norvegicus	54.97	5.00e-95	343.00
IUUC-Sce-106420	Saccharomyces cerevisiae	30.77	4.00e-49	187.00
IUUC-Sha-106829	Sarcophilus harrisii	52.73	8.00e-94	336.00
IUUC-Sja-107923	Schizosaccharomyces japonicus	34.93	1.00e-53	202.00
IUUC-Spo-108184	Schizosaccharomyces pombe	34.71	5.00e-55	207.00
IUUC-Smo-109282	Selaginella moellendorffii	32.09	8.00e-33	133.00
IUUC-Sar-113279	Sorex araneus	55.99	3.00e-88	317.00
IUUC-Ssc-115589	Sus scrofa	56.06	6.00e-90	323.00
IUUC-Tgu-117523	Taeniopygia guttata	56.62	3.00e-105	374.00
IUUC-Tru-117985	Takifugu rubripes	53.27	8.00e-91	328.00
IUUC-Tsy-118913	Tarsius syrichta	56.30	2.00e-80	291.00
IUUC-Tni-120670	Tetraodon nigroviridis	56.46	2.00e-107	381.00
IUUC-Tme-126885	Tuber melanosporum	33.43	1.00e-48	185.00
IUUC-Tbe-127344	Tupaia belangeri	46.42	4.00e-73	267.00
IUUC-Ttr-128347	Tursiops truncatus	56.34	3.00e-88	317.00
IUUC-Vpa-130656	Vicugna pacos	55.99	9.00e-88	316.00
IUUC-Xtr-132736	Xenopus tropicalis	57.01	1.00e-106	379.00
IUUC-Xma-133678	Xiphophorus maculatus	56.76	5.00e-108	383.00
IUUC-Yli-134659	Yarrowia lipolytica	37.46	3.00e-60	224.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence