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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-032148
Ensembl Protein ID FBpp0088620
UniProt Accession P27398; O61346; Q7KU57; Q7KU58; Q8MQP3; Q9VRH3; Q9VRH4; CAND_DROME
Genbank Protein ID AAB95431.1; AAC28409.1; AAF50826.4; AAF50827.3; AAS65411.2; AAM75061.1
Protein Name Calpain-D; Calcium-activated neutral proteinase D; Small optic lobes protein
Genbank Nucleotide ID M64084; AF017777; AE014298; AE014298; AE014298; AY128468
Gene Name sol; CalpD; CG1391
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0003464 FBtr0301583 FBpp0290798
FBgn0003464 FBtr0346608 FBpp0312188
FBgn0003464 FBtr0089679 FBpp0088621
FBgn0003464 FBtr0089678 FBpp0088620
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Post-translational Modifications (PTMs)
dbPAFdbPTMPhospho.ELMUniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/ZnF/NZF 1.80e-20 72.2 930 955
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/ZnF/NZF
   S: 4    qWaCsaCTflNePeavkCemCsrpRg 29
           +W+C+aCT+ N +++v+C +Cs pRg
   Q: 930  KWQCPACTYDNCAASVVCDICSSPRG 955
           8************************8 PP
   
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     Calcium-regulated non-lysosomal thiol-protease.
 Calcium-regulated non-lysosomal thiol-protease.
Protein Sequence
(Fasta)
MGTISSVLQW SCTKCNTINP TESLKCFNCG TVRKVFPQQQ QQQHRSSSIT ASWTADDALE 60
QEQAEKGQER DKEKGRAAVA RSEYKHVYKS LLRGCLKRPQ RNSQNLPANC VDCEDTRKYI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-032148|UBD,NZF|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTTGTCGTTG GAGGTGTTCG CGAACGTCGA CAACCCTAGC GGCAACAGTT AAAAAATGGT 60
GTGAAACGGC GACGGAGAAC GCGGCGTGCA ACTGTTGGAA GCCACTGCTT GGTCCTCGTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-032148|UBD,NZF|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-0645--Protease
KW-1185--Reference proteome
KW-0677--Repeat
KW-0716--Sensory transduction
KW-0788--Thiol protease
KW-0844--Vision
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR022684--Calpain_cysteine_protease
IPR000169--Pept_cys_AS
IPR001300--Peptidase_C2_calpain_cat
IPR001876--Znf_RanBP2
PROSITE

PS50203--CALPAIN_CAT
PS00139--THIOL_PROTEASE_CYS
PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
Pfam

PF00648--Peptidase_C2
PF00641--zf-RanBP
PRINTS

PR00704--CALPAIN
SMART

SM00230--CysPc
SM00547--ZnF_RBZ
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005622--C:intracellular
GO:0004198--F:calcium-dependent cysteine-type endopeptidase activity
GO:0008270--F:zinc ion binding
GO:0007399--P:nervous system development
GO:0006508--P:proteolysis
GO:0010378--P:temperature compensation of the circadian clock
GO:0007601--P:visual perception
KEGG dme:Dmel_CG1391
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001505 Ailuropoda melanoleuca 54.29 0.00e+00 677.00
IUUC-Apl-003593 Anas platyrhynchos 52.18 0.00e+00 640.00
IUUC-Aca-005082 Anolis carolinensis 55.77 0.00e+00 744.00
IUUC-Aly-006462 Arabidopsis lyrata 36.92 2.00e-05 42.70
IUUC-Acl-008308 Aspergillus clavatus 46.67 1.10e-02 33.90
IUUC-Afl-008658 Aspergillus flavus 45.83 3.90e-02 32.00
IUUC-Afu-008913 Aspergillus fumigatus 46.67 1.20e-02 33.50
IUUC-Ang-009619 Aspergillus niger 50.00 9.00e-03 33.90
IUUC-Aor-009946 Aspergillus oryzae 45.83 3.90e-02 32.00
IUUC-Bta-013065 Bos taurus 54.24 0.00e+00 696.00
IUUC-Bdi-014770 Brachypodium distachyon 38.46 5.00e-05 41.20
IUUC-Bol-015716 Brassica oleracea 35.38 1.00e-04 40.40
IUUC-Bra-017928 Brassica rapa 35.38 3.00e-05 42.00
IUUC-Cja-019708 Callithrix jacchus 52.82 2.00e-167 582.00
IUUC-Cfa-020860 Canis familiaris 54.36 0.00e+00 691.00
IUUC-Cpo-022525 Cavia porcellus 54.80 0.00e+00 702.00
IUUC-Csa-023316 Chlorocebus sabaeus 55.75 3.00e-152 531.00
IUUC-Dre-028676 Danio rerio 54.94 0.00e+00 738.00
IUUC-Dno-029448 Dasypus novemcinctus 58.07 2.00e-121 429.00
IUUC-Dor-030214 Dipodomys ordii 55.43 0.00e+00 703.00
IUUC-Eca-033450 Equus caballus 53.82 2.00e-146 512.00
IUUC-Eeu-034986 Erinaceus europaeus 49.50 9.00e-67 248.00
IUUC-Fca-036018 Felis catus 51.72 0.00e+00 635.00
IUUC-Fal-037308 Ficedula albicollis 54.84 0.00e+00 741.00
IUUC-Gga-041032 Gallus gallus 54.61 0.00e+00 735.00
IUUC-Gma-043646 Glycine max 36.92 1.00e-06 46.60
IUUC-Ggo-045635 Gorilla gorilla 53.71 0.00e+00 677.00
IUUC-Hsa-045791 Homo sapiens 54.59 0.00e+00 690.00
IUUC-Itr-048401 Ictidomys tridecemlineatus 54.01 0.00e+00 695.00
IUUC-Lch-050282 Latimeria chalumnae 51.67 0.00e+00 637.00
IUUC-Lpe-050735 Leersia perrieri 38.46 3.00e-05 42.00
IUUC-Loc-052478 Lepisosteus oculatus 50.36 0.00e+00 656.00
IUUC-Laf-054556 Loxodonta africana 55.84 0.00e+00 662.00
IUUC-Mcc-054669 Macaca mulatta 54.31 0.00e+00 684.00
IUUC-Meu-056257 Macropus eugenii 56.13 2.00e-69 256.00
IUUC-Mor-057018 Magnaporthe oryzae 42.86 1.40e-02 33.50
IUUC-Mpo-057432 Magnaporthe poae 25.71 8.10e-02 31.20
IUUC-Mtr-058133 Medicago truncatula 38.46 5.00e-07 48.10
IUUC-Mga-059232 Meleagris gallopavo 53.85 0.00e+00 717.00
IUUC-Mmr-061524 Microcebus murinus 55.02 0.00e+00 701.00
IUUC-Mdo-062883 Monodelphis domestica 55.57 0.00e+00 741.00
IUUC-Mmu-064018 Mus musculus 52.15 0.00e+00 692.00
IUUC-Mac-064717 Musa acuminata 40.98 6.00e-08 50.80
IUUC-Mpu-066215 Mustela putorius furo 54.51 0.00e+00 693.00
IUUC-Mlu-067181 Myotis lucifugus 54.66 0.00e+00 697.00
IUUC-Nfi-068513 Neosartorya fischeri 46.67 1.20e-02 33.50
IUUC-Opr-070414 Ochotona princeps 54.84 0.00e+00 694.00
IUUC-Ont-072063 Oreochromis niloticus 54.90 0.00e+00 731.00
IUUC-Oan-073086 Ornithorhynchus anatinus 57.21 2.00e-137 482.00
IUUC-Ocu-074037 Oryctolagus cuniculus 52.94 0.00e+00 655.00
IUUC-Oba-075102 Oryza barthii 36.92 2.00e-04 39.30
IUUC-Ogl-077291 Oryza glaberrima 36.92 2.00e-04 39.30
IUUC-Oin-079800 Oryza indica 36.92 2.00e-04 39.30
IUUC-Ome-081262 Oryza meridionalis 34.55 1.50e-02 33.10
IUUC-Oni-082829 Oryza nivara 36.92 2.00e-04 39.30
IUUC-Oru-084564 Oryza rufipogon 36.92 2.00e-04 39.30
IUUC-Osa-085600 Oryza sativa 36.92 2.00e-04 39.30
IUUC-Ola-086498 Oryzias latipes 54.77 0.00e+00 728.00
IUUC-Oga-088087 Otolemur garnettii 54.73 0.00e+00 712.00
IUUC-Pan-092918 Papio anubis 55.28 5.00e-147 514.00
IUUC-Pma-094435 Petromyzon marinus 45.48 0.00e+00 699.00
IUUC-Ppa-095486 Physcomitrella patens 40.00 3.00e-07 48.90
IUUC-Pfo-096574 Poecilia formosa 55.48 0.00e+00 754.00
IUUC-Pab-098098 Pongo abelii 53.92 5.00e-111 395.00
IUUC-Pop-099256 Populus trichocarpa 37.33 1.00e-08 53.10
IUUC-Pca-100428 Procavia capensis 52.79 0.00e+00 648.00
IUUC-Ppe-101337 Prunus persica 35.53 7.00e-06 44.30
IUUC-Pte-104280 Pyrenophora teres 40.00 1.30e-01 30.40
IUUC-Rno-105671 Rattus norvegicus 52.29 0.00e+00 695.00
IUUC-Sha-106877 Sarcophilus harrisii 55.39 0.00e+00 737.00
IUUC-Ssl-108588 Sclerotinia sclerotiorum 25.00 3.20e-02 32.30
IUUC-Sit-110033 Setaria italica 41.10 6.00e-08 50.80
IUUC-Sly-111119 Solanum lycopersicum 37.70 5.00e-06 45.10
IUUC-Sbi-113896 Sorghum bicolor 43.08 3.00e-07 48.50
IUUC-Ssc-115957 Sus scrofa 54.41 0.00e+00 689.00
IUUC-Tgu-116764 Taeniopygia guttata 54.32 0.00e+00 724.00
IUUC-Tru-118000 Takifugu rubripes 55.33 0.00e+00 729.00
IUUC-Tni-119762 Tetraodon nigroviridis 51.40 0.00e+00 660.00
IUUC-Tca-121382 Theobroma cacao 38.46 2.00e-07 48.90
IUUC-Ttr-128978 Tursiops truncatus 54.69 0.00e+00 698.00
IUUC-Vda-130005 Verticillium dahliae 43.33 1.50e-02 33.10
IUUC-Vvi-131427 Vitis vinifera 35.38 2.00e-05 42.70
IUUC-Xtr-132023 Xenopus tropicalis 54.41 0.00e+00 720.00
Created Date 25-Jun-2017

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