iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.90e-21	73.2	107	147

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtcla.f......sd.tllvsGsdDgtikvWDlrtgv 34
           H++ ++ ++         + + +v+Gs+Dg +kvWD+r+g 
   Q: 107  HNGIINTIDaIggtqidCGaPEIVTGSRDGAVKVWDIRQGQ 147
           6666666653466666544688***************9986 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MDKPQLIEHL HEALNYTVYD TKWVPLSAKF VILGSKANGH GIMDIYELNQ DKLVKVKSVE 60
KKVAFKCGTF GAASLRNRHM AIGDFEGRLQ VLDMEQPDLP VYNVKAHNGI INTIDAIGGT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAAGAGATAG CCATGACAAC AAAACAACTT GTTTTTGATA AATCCTTAAG TTTTCACCGG 60
CCGCTTTTGG AATATTAGCA TAAAGTTGAG ACGGAAATAT AGATCGTTGA AATGGACAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005955--C:calcineurin complex
GO:0019904--F:protein domain specific binding
GO:0033173--P:calcineurin-NFAT signaling cascade
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0019233--P:sensory perception of pain

KEGG

dme:Dmel_CG14353

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001641	Ailuropoda melanoleuca	55.76	9.00e-121	426.00
IUUC-Apl-003566	Anas platyrhynchos	54.55	3.00e-99	355.00
IUUC-Aca-004379	Anolis carolinensis	54.42	2.00e-118	419.00
IUUC-Ame-011892	Astyanax mexicanus	56.30	8.00e-122	429.00
IUUC-Bta-013172	Bos taurus	55.76	4.00e-122	430.00
IUUC-Cja-019636	Callithrix jacchus	54.69	7.00e-119	420.00
IUUC-Cfa-020693	Canis familiaris	56.30	4.00e-122	431.00
IUUC-Cpo-022505	Cavia porcellus	56.42	4.00e-115	407.00
IUUC-Cre-022581	Chlamydomonas reinhardtii	51.08	2.00e-108	384.00
IUUC-Csa-023448	Chlorocebus sabaeus	54.96	7.00e-120	422.00
IUUC-Cho-025072	Choloepus hoffmanni	51.13	6.00e-87	313.00
IUUC-Cin-025477	Ciona intestinalis	54.69	2.00e-115	407.00
IUUC-Csv-026095	Ciona savignyi	47.88	4.00e-88	317.00
IUUC-Dre-028504	Danio rerio	55.35	2.00e-120	424.00
IUUC-Dno-028991	Dasypus novemcinctus	56.03	1.00e-121	428.00
IUUC-Dor-030198	Dipodomys ordii	51.47	4.00e-110	390.00
IUUC-Ete-032891	Echinops telfairi	56.03	3.00e-121	428.00
IUUC-Eca-033980	Equus caballus	55.76	2.00e-121	427.00
IUUC-Eeu-035248	Erinaceus europaeus	49.33	7.00e-102	364.00
IUUC-Fca-035816	Felis catus	56.03	2.00e-122	431.00
IUUC-Fal-037423	Ficedula albicollis	55.23	2.00e-123	434.00
IUUC-Gmo-039717	Gadus morhua	54.50	3.00e-113	401.00
IUUC-Gga-040937	Gallus gallus	55.50	3.00e-123	433.00
IUUC-Gac-042520	Gasterosteus aculeatus	55.26	5.00e-118	417.00
IUUC-Ggo-045335	Gorilla gorilla	55.50	1.00e-120	426.00
IUUC-Hsa-046065	Homo sapiens	55.76	1.00e-114	405.00
IUUC-Itr-048758	Ictidomys tridecemlineatus	56.27	3.00e-116	410.00
IUUC-Lch-050048	Latimeria chalumnae	57.10	5.00e-116	410.00
IUUC-Loc-052214	Lepisosteus oculatus	53.44	2.00e-112	398.00
IUUC-Laf-054161	Loxodonta africana	55.76	9.00e-122	429.00
IUUC-Mcc-055366	Macaca mulatta	55.23	2.00e-120	424.00
IUUC-Meu-056555	Macropus eugenii	49.04	5.00e-67	246.00
IUUC-Mga-059823	Meleagris gallopavo	56.36	3.00e-97	348.00
IUUC-Mmr-061739	Microcebus murinus	56.03	5.00e-115	406.00
IUUC-Mdo-061852	Monodelphis domestica	56.03	2.00e-123	434.00
IUUC-Mmu-063204	Mus musculus	56.53	4.00e-123	433.00
IUUC-Mpu-065991	Mustela putorius furo	56.03	3.00e-122	430.00
IUUC-Mlu-067191	Myotis lucifugus	56.03	1.00e-120	426.00
IUUC-Nle-069750	Nomascus leucogenys	55.50	6.00e-121	426.00
IUUC-Opr-070193	Ochotona princeps	56.80	4.00e-123	434.00
IUUC-Ont-071758	Oreochromis niloticus	56.30	2.00e-115	408.00
IUUC-Oan-072776	Ornithorhynchus anatinus	51.53	1.00e-43	168.00
IUUC-Ocu-074633	Oryctolagus cuniculus	56.80	9.00e-124	435.00
IUUC-Ola-086652	Oryzias latipes	55.35	1.00e-117	416.00
IUUC-Olu-087833	Ostreococcus lucimarinus	43.17	2.00e-83	301.00
IUUC-Oga-088666	Otolemur garnettii	56.57	4.00e-116	410.00
IUUC-Oar-089500	Ovis aries	54.42	7.00e-116	409.00
IUUC-Ptr-090681	Pan troglodytes	55.50	6.00e-121	426.00
IUUC-Pan-092588	Papio anubis	55.23	2.00e-120	424.00
IUUC-Psi-093562	Pelodiscus sinensis	59.22	8.00e-76	275.00
IUUC-Pma-094744	Petromyzon marinus	53.85	2.00e-85	307.00
IUUC-Ppa-095392	Physcomitrella patens	53.23	7.00e-114	402.00
IUUC-Pfo-096229	Poecilia formosa	55.88	5.00e-120	424.00
IUUC-Pab-097848	Pongo abelii	55.50	1.00e-120	426.00
IUUC-Pca-100296	Procavia capensis	44.50	5.00e-88	317.00
IUUC-Pva-102495	Pteropus vampyrus	50.67	4.00e-104	370.00
IUUC-Rno-105437	Rattus norvegicus	56.53	2.00e-115	407.00
IUUC-Sha-107141	Sarcophilus harrisii	55.10	4.00e-118	416.00
IUUC-Smo-109154	Selaginella moellendorffii	52.15	2.00e-111	394.00
IUUC-Sar-113523	Sorex araneus	58.25	6.00e-103	367.00
IUUC-Ssc-116433	Sus scrofa	56.30	8.00e-122	430.00
IUUC-Tgu-116611	Taeniopygia guttata	56.18	8.00e-124	435.00
IUUC-Tru-118356	Takifugu rubripes	54.42	3.00e-117	414.00
IUUC-Tsy-119597	Tarsius syrichta	56.03	6.00e-113	399.00
IUUC-Tni-120540	Tetraodon nigroviridis	54.16	4.00e-118	416.00
IUUC-Tbe-127572	Tupaia belangeri	57.96	5.00e-51	194.00
IUUC-Ttr-128590	Tursiops truncatus	55.50	2.00e-120	424.00
IUUC-Vpa-130158	Vicugna pacos	56.30	2.00e-122	431.00
IUUC-Xtr-131856	Xenopus tropicalis	54.68	2.00e-77	281.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence