iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E2/UBC	2.90e-26	91.9	18	131

Active Site

Position(s)	Description	Evidence
96	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00388}

Domain Profile

E2/UBC

   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilk.eeekWspals 97
           R+k+++++l++dp ++i+a+p  + ++ ew++ + Gped+pY gg+++ ++ fp+++PfkPP++ +lt+  ++ +++n+++Clsi + ++++W+p++ 
   Q: 18   RMKQDYMRLKRDPLPYITAEPLPN-NILEWHYCVKGPEDSPYYGGYYHGTLLFPREFPFKPPSIYMLTP--NGRFKTNTRLCLSISDfHPDTWNPTWC 112
           899*********************.9*******************************************..9999999********889********* PP
   S: 98   vesvllsiqsllaepnpes 116
           v ++l+++ s++ e  p  
   Q: 113  VGTILTGLLSFMLESTPTL 131
           ************7765544 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSSSSTSGGR KQPTAVSRMK QDYMRLKRDP LPYITAEPLP NNILEWHYCV KGPEDSPYYG 60
GYYHGTLLFP REFPFKPPSI YMLTPNGRFK TNTRLCLSIS DFHPDTWNPT WCVGTILTGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GAGATGAAAC TTACTTCCGC ACACGGTACC ACTAAACTCT TCATGCCAAA ATAAAAGATT 60
AAATTAAGAT ATTGCCAGCT CCAAACCCGG ATATATAACC CCACAAGTGA TTAATACGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR000608--UBQ-conjugat_E2
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0005789--C:endoplasmic reticulum membrane
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0042335--P:cuticle development
GO:0000209--P:protein polyubiquitination
GO:0016567--P:protein ubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

dme:Dmel_CG5823

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001180	Aegilops tauschii	49.30	3.00e-22	99.00
IUUC-Aml-002152	Ailuropoda melanoleuca	50.71	1.00e-77	281.00
IUUC-Atr-003156	Amborella trichopoda	53.59	4.00e-52	196.00
IUUC-Apl-004224	Anas platyrhynchos	71.88	2.00e-70	258.00
IUUC-Aca-005049	Anolis carolinensis	68.97	2.00e-75	274.00
IUUC-Aly-006195	Arabidopsis lyrata	50.96	4.00e-50	190.00
IUUC-Ath-006640	Arabidopsis thaliana	50.32	2.00e-50	191.00
IUUC-Ago-007987	Ashbya gossypii	51.88	1.00e-50	191.00
IUUC-Acl-008060	Aspergillus clavatus	50.72	3.00e-40	157.00
IUUC-Afl-008561	Aspergillus flavus	50.72	4.00e-40	157.00
IUUC-Afu-008860	Aspergillus fumigatus	50.72	5.00e-40	157.00
IUUC-Ani-009333	Aspergillus nidulans	49.28	2.00e-39	154.00
IUUC-Ang-009810	Aspergillus niger	51.45	1.00e-40	158.00
IUUC-Aor-010127	Aspergillus oryzae	50.72	4.00e-40	157.00
IUUC-Ate-010362	Aspergillus terreus	50.72	4.00e-40	157.00
IUUC-Ame-010627	Astyanax mexicanus	49.13	1.00e-77	281.00
IUUC-Bgr-012069	Blumeria graminis	49.28	3.00e-38	150.00
IUUC-Bta-012472	Bos taurus	51.43	4.00e-77	280.00
IUUC-Bci-013843	Botrytis cinerea	52.90	2.00e-40	158.00
IUUC-Bdi-014467	Brachypodium distachyon	50.30	7.00e-48	182.00
IUUC-Bol-016116	Brassica oleracea	50.32	2.00e-50	191.00
IUUC-Bra-017777	Brassica rapa	50.33	3.00e-49	187.00
IUUC-Cel-018278	Caenorhabditis elegans	56.25	4.00e-48	183.00
IUUC-Cja-018817	Callithrix jacchus	44.41	2.00e-60	224.00
IUUC-Cfa-020885	Canis familiaris	50.36	6.00e-77	279.00
IUUC-Cpo-022326	Cavia porcellus	51.07	4.00e-78	283.00
IUUC-Cre-022635	Chlamydomonas reinhardtii	54.14	2.00e-53	200.00
IUUC-Csa-023646	Chlorocebus sabaeus	52.50	2.00e-79	287.00
IUUC-Cho-025075	Choloepus hoffmanni	60.53	1.00e-49	187.00
IUUC-Cin-025389	Ciona intestinalis	71.88	4.00e-72	262.00
IUUC-Csv-026315	Ciona savignyi	50.00	3.00e-73	266.00
IUUC-Cgl-026602	Colletotrichum gloeosporioides	52.17	2.00e-41	161.00
IUUC-Cne-026808	Cryptococcus neoformans	46.48	3.00e-41	159.00
IUUC-Cme-027189	Cyanidioschyzon merolae	44.07	4.00e-22	97.80
IUUC-Dre-028455	Danio rerio	51.09	8.00e-80	288.00
IUUC-Dno-029667	Dasypus novemcinctus	51.43	1.00e-78	285.00
IUUC-Dor-030747	Dipodomys ordii	42.57	1.00e-59	222.00
IUUC-Dse-031231	Dothistroma septosporum	47.83	6.00e-38	149.00
IUUC-Ete-032258	Echinops telfairi	48.66	5.00e-74	270.00
IUUC-Eca-033602	Equus caballus	35.00	1.00e-42	166.00
IUUC-Eeu-034443	Erinaceus europaeus	47.53	1.00e-53	201.00
IUUC-Fca-036167	Felis catus	46.81	2.00e-65	241.00
IUUC-Fal-037114	Ficedula albicollis	72.50	5.00e-71	259.00
IUUC-Fox-037957	Fusarium oxysporum	56.67	2.00e-39	155.00
IUUC-Fso-038277	Fusarium solani	53.62	2.00e-42	164.00
IUUC-Gmo-039501	Gadus morhua	68.42	1.00e-74	271.00
IUUC-Ggr-040010	Gaeumannomyces graminis	54.35	2.00e-43	167.00
IUUC-Gga-041257	Gallus gallus	71.88	9.00e-71	258.00
IUUC-Gac-041433	Gasterosteus aculeatus	69.01	3.00e-75	273.00
IUUC-Gma-043529	Glycine max	43.07	4.00e-51	193.00
IUUC-Ggo-044437	Gorilla gorilla	48.02	2.00e-61	228.00
IUUC-Hsa-046693	Homo sapiens	52.50	2.00e-79	287.00
IUUC-Hvu-047328	Hordeum vulgare	42.65	5.00e-32	130.00
IUUC-Itr-048477	Ictidomys tridecemlineatus	51.07	9.00e-77	278.00
IUUC-Kpa-049391	Komagataella pastoris	52.41	2.00e-41	161.00
IUUC-Lch-049617	Latimeria chalumnae	71.25	2.00e-70	257.00
IUUC-Lpe-050949	Leersia perrieri	49.40	5.00e-47	180.00
IUUC-Loc-052157	Lepisosteus oculatus	51.40	1.00e-77	281.00
IUUC-Lma-053128	Leptosphaeria maculans	52.86	6.00e-42	163.00
IUUC-Laf-054455	Loxodonta africana	51.79	9.00e-77	278.00
IUUC-Mcc-054756	Macaca mulatta	52.50	2.00e-79	287.00
IUUC-Meu-056106	Macropus eugenii	41.98	6.00e-55	206.00
IUUC-Mor-057202	Magnaporthe oryzae	52.90	1.00e-42	165.00
IUUC-Mpo-057349	Magnaporthe poae	54.35	3.00e-43	167.00
IUUC-Mtr-058271	Medicago truncatula	41.06	9.00e-47	179.00
IUUC-Mla-058894	Melampsora laricipopulina	49.64	5.00e-43	166.00
IUUC-Mga-059493	Meleagris gallopavo	71.88	9.00e-71	258.00
IUUC-Mvi-060232	Microbotryum violaceum	47.80	3.00e-45	174.00
IUUC-Mmr-060957	Microcebus murinus	50.71	6.00e-78	282.00
IUUC-Mdo-062141	Monodelphis domestica	51.77	6.00e-77	279.00
IUUC-Mmu-063882	Mus musculus	70.35	8.00e-76	275.00
IUUC-Mac-064530	Musa acuminata	48.75	2.00e-47	181.00
IUUC-Mpu-065902	Mustela putorius furo	50.71	3.00e-77	280.00
IUUC-Mlu-068008	Myotis lucifugus	51.79	3.00e-75	273.00
IUUC-Nfi-068515	Neosartorya fischeri	50.72	3.00e-40	157.00
IUUC-Ncr-068755	Neurospora crassa	51.45	9.00e-41	159.00
IUUC-Nle-069166	Nomascus leucogenys	42.75	6.00e-33	133.00
IUUC-Opr-071201	Ochotona princeps	47.98	1.00e-52	198.00
IUUC-Ont-071311	Oreochromis niloticus	68.60	4.00e-75	273.00
IUUC-Oan-073310	Ornithorhynchus anatinus	70.35	1.00e-75	275.00
IUUC-Ocu-074514	Oryctolagus cuniculus	51.07	1.00e-77	281.00
IUUC-Oba-075200	Oryza barthii	49.40	4.00e-47	180.00
IUUC-Obr-076396	Oryza brachyantha	49.70	8.00e-48	182.00
IUUC-Ogl-077398	Oryza glaberrima	49.40	6.00e-47	179.00
IUUC-Ogu-078362	Oryza glumaepatula	49.40	4.00e-47	180.00
IUUC-Oin-079625	Oryza indica	49.40	4.00e-47	180.00
IUUC-Olo-080620	Oryza longistaminata	45.04	5.00e-28	116.00
IUUC-Ome-081187	Oryza meridionalis	49.40	6.00e-47	179.00
IUUC-Oni-082271	Oryza nivara	50.00	1.00e-47	181.00
IUUC-Opu-083487	Oryza punctata	48.80	3.00e-46	177.00
IUUC-Oru-085263	Oryza rufipogon	49.40	4.00e-47	180.00
IUUC-Osa-085694	Oryza sativa	49.40	4.00e-47	180.00
IUUC-Ola-086450	Oryzias latipes	51.80	9.00e-77	278.00
IUUC-Olu-087750	Ostreococcus lucimarinus	42.72	1.00e-23	100.00
IUUC-Oga-088054	Otolemur garnettii	47.30	4.00e-72	263.00
IUUC-Oar-089486	Ovis aries	51.79	5.00e-78	283.00
IUUC-Ptr-091314	Pan troglodytes	42.75	6.00e-33	133.00
IUUC-Pan-092633	Papio anubis	52.50	2.00e-79	287.00
IUUC-Psi-093668	Pelodiscus sinensis	43.20	2.00e-31	128.00
IUUC-Pno-095025	Phaeosphaeria nodorum	52.14	4.00e-43	167.00
IUUC-Ppa-095641	Physcomitrella patens	52.60	4.00e-52	197.00
IUUC-Pfo-096423	Poecilia formosa	71.70	7.00e-71	259.00
IUUC-Pab-097771	Pongo abelii	52.50	2.00e-79	287.00
IUUC-Pop-099714	Populus trichocarpa	50.00	4.00e-52	196.00
IUUC-Pca-100493	Procavia capensis	40.93	2.00e-42	164.00
IUUC-Ppe-102054	Prunus persica	50.62	3.00e-51	194.00
IUUC-Pva-102224	Pteropus vampyrus	51.43	3.00e-77	280.00
IUUC-Pgr-103332	Puccinia graminis	49.33	7.00e-46	176.00
IUUC-Ptt-103776	Puccinia triticina	49.33	7.00e-46	176.00
IUUC-Pte-104166	Pyrenophora teres	52.86	3.00e-43	167.00
IUUC-Pyt-104570	Pyrenophora triticirepentis	52.86	4.00e-43	167.00
IUUC-Rno-105593	Rattus norvegicus	70.93	3.00e-76	277.00
IUUC-Sce-106212	Saccharomyces cerevisiae	55.48	1.00e-51	195.00
IUUC-Sha-106767	Sarcophilus harrisii	52.14	5.00e-77	279.00
IUUC-Sja-107907	Schizosaccharomyces japonicus	51.61	1.00e-49	188.00
IUUC-Spo-108094	Schizosaccharomyces pombe	48.75	2.00e-47	181.00
IUUC-Ssl-108556	Sclerotinia sclerotiorum	52.90	1.00e-40	159.00
IUUC-Smo-108965	Selaginella moellendorffii	51.30	2.00e-51	194.00
IUUC-Sit-110407	Setaria italica	51.88	2.00e-48	184.00
IUUC-Sly-111642	Solanum lycopersicum	46.70	1.00e-47	182.00
IUUC-Stu-112336	Solanum tuberosum	45.70	5.00e-47	179.00
IUUC-Sar-113063	Sorex araneus	43.07	2.00e-33	135.00
IUUC-Sbi-114327	Sorghum bicolor	52.20	2.00e-48	184.00
IUUC-Sre-115170	Sporisorium reilianum	51.63	1.00e-40	158.00
IUUC-Ssc-116385	Sus scrofa	50.71	7.00e-78	282.00
IUUC-Tgu-117041	Taeniopygia guttata	72.50	2.00e-71	261.00
IUUC-Tru-117697	Takifugu rubripes	69.64	8.00e-75	272.00
IUUC-Tsy-119024	Tarsius syrichta	48.21	5.00e-65	239.00
IUUC-Tni-120466	Tetraodon nigroviridis	67.05	3.00e-72	263.00
IUUC-Tca-121569	Theobroma cacao	50.31	1.00e-49	188.00
IUUC-Tre-121882	Trichoderma reesei	53.62	9.00e-43	166.00
IUUC-Tvi-122466	Trichoderma virens	52.90	1.00e-42	165.00
IUUC-Tae-124592	Triticum aestivum	50.60	4.00e-49	187.00
IUUC-Tur-126536	Triticum urartu	50.00	1.00e-47	181.00
IUUC-Tme-127051	Tuber melanosporum	52.90	4.00e-42	164.00
IUUC-Tbe-128095	Tupaia belangeri	73.45	4.00e-50	189.00
IUUC-Ttr-128466	Tursiops truncatus	51.43	1.00e-77	281.00
IUUC-Uma-129383	Ustilago maydis	51.63	3.00e-40	157.00
IUUC-Vda-130013	Verticillium dahliae	52.24	2.00e-40	158.00
IUUC-Vpa-130404	Vicugna pacos	40.69	8.00e-33	133.00
IUUC-Vvi-131251	Vitis vinifera	50.32	6.00e-48	183.00
IUUC-Xtr-132408	Xenopus tropicalis	51.43	1.00e-79	288.00
IUUC-Xma-133893	Xiphophorus maculatus	71.70	4.00e-71	260.00
IUUC-Yli-134618	Yarrowia lipolytica	55.41	3.00e-48	183.00
IUUC-Zma-135216	Zea mays	50.62	2.00e-48	184.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence