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Basic Information Integrated Annotations

Tag Content
iUUCD ID IUUC-Mmu-063596
Ensembl Protein ID ENSMUSP00000003268.9
UniProt Accession Q62419; SH3G1_MOUSE
Genbank Protein ID AAC71775.1
Protein Name Endophilin-A2; Endophilin-2; SH3 domain protein 2B; SH3 domain-containing GRB2-like protein 1; SH3p8
Genbank Nucleotide ID U58885
Gene Name Sh3gl1; Sh3d2b
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000003200.9 ENSMUST00000003268.9 ENSMUSP00000003268.9
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IIDPINAHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.30e-13 51.0 310 363
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
    +++lyd+e++nd+eL +++Gd +++ ++ de+W +g l+g++G+fP +v+ l
   Q: 310 SCKALYDFEPENDGELGFREGDLITLT--NQIDENWYEG--MLHGQSGFFPLSYVQVL 363
    69************************7..99********..8************9865 PP
   

Organism Mus musculus
Functional Description
(View)

Functional Description



     Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Protein Sequence
(Fasta)
MSVAGLKKQF YKASQLVSEK VGGAEGTKLD DDFKDMEKKV DVTSKAVAEV LVRTIEYLQP 60
NPASRAKLTM LNTVSKIRGQ VKNPGYPQSE GLLGECMVRH GKELGGESNF GDALLDAGES 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mmu-063596|UBD,SH3|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTAATATCCC GGCCGCGCGT GCGCGCTAGC CGGCCGAGGT GGCTTCGGGG CGGGGGCGCA 60
GAGCTGGCAA GCTGATTTGG CGGTGGCGGC GCCGACCTGC GCGCGGAGGA AAGAAGTCGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mmu-063596|UBD,SH3|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0965--Cell junction
KW-0966--Cell projection
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0903--Direct protein sequencing
KW-0254--Endocytosis
KW-0967--Endosome
KW-0446--Lipid-binding
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS50002--SH3

Pfam

PF03114--BAR
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00721--BAR
SM00326--SH3

Gene Ontology

GO:0042995--C:cell projection
GO:0005913--C:cell-cell adherens junction
GO:0005737--C:cytoplasm
GO:0031901--C:early endosome membrane
GO:0002102--C:podosome
GO:0045202--C:synapse
GO:0098641--F:cadherin binding involved in cell-cell adhesion
GO:0042802--F:identical protein binding
GO:0008289--F:lipid binding
GO:0016191--P:synaptic vesicle uncoating

KEGG mmu:20405
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001620 Ailuropoda melanoleuca 92.78 0.00e+00 652.00
IUUC-Apl-004209 Anas platyrhynchos 87.08 3.00e-172 597.00
IUUC-Ame-011047 Astyanax mexicanus 75.07 1.00e-155 542.00
IUUC-Bta-012875 Bos taurus 93.75 0.00e+00 711.00
IUUC-Cel-018509 Caenorhabditis elegans 44.59 3.00e-94 338.00
IUUC-Cin-025799 Ciona intestinalis 50.95 1.00e-103 369.00
IUUC-Csv-026266 Ciona savignyi 52.49 1.00e-101 362.00
IUUC-Cne-027089 Cryptococcus neoformans 25.74 8.00e-08 52.40
IUUC-Dre-027986 Danio rerio 73.19 7.00e-154 536.00
IUUC-Dno-029193 Dasypus novemcinctus 94.57 0.00e+00 687.00
IUUC-Dor-030288 Dipodomys ordii 85.33 2.00e-173 601.00
IUUC-Eca-033277 Equus caballus 94.07 0.00e+00 651.00
IUUC-Fal-036965 Ficedula albicollis 87.57 0.00e+00 628.00
IUUC-Gmo-039523 Gadus morhua 72.75 2.00e-151 528.00
IUUC-Gga-040426 Gallus gallus 88.04 0.00e+00 630.00
IUUC-Gac-042642 Gasterosteus aculeatus 75.41 3.00e-158 551.00
IUUC-Ggo-045448 Gorilla gorilla 94.02 0.00e+00 683.00
IUUC-Hsa-046112 Homo sapiens 94.02 0.00e+00 683.00
IUUC-Itr-048752 Ictidomys tridecemlineatus 95.65 0.00e+00 696.00
IUUC-Lch-050334 Latimeria chalumnae 69.01 1.00e-132 465.00
IUUC-Loc-052447 Lepisosteus oculatus 77.75 9.00e-169 585.00
IUUC-Laf-053698 Loxodonta africana 94.29 0.00e+00 717.00
IUUC-Mcc-055547 Macaca mulatta 88.86 2.00e-177 614.00
IUUC-Meu-056398 Macropus eugenii 78.26 2.00e-167 581.00
IUUC-Mga-060168 Meleagris gallopavo 85.39 5.00e-171 593.00
IUUC-Mmr-061056 Microcebus murinus 93.75 0.00e+00 682.00
IUUC-Mpu-066681 Mustela putorius furo 94.02 0.00e+00 684.00
IUUC-Mlu-068113 Myotis lucifugus 87.92 0.00e+00 634.00
IUUC-Nle-070104 Nomascus leucogenys 93.05 9.00e-175 605.00
IUUC-Opr-070661 Ochotona princeps 93.78 0.00e+00 680.00
IUUC-Ont-071922 Oreochromis niloticus 75.00 5.00e-157 546.00
IUUC-Ola-086645 Oryzias latipes 77.03 2.00e-170 591.00
IUUC-Oga-088627 Otolemur garnettii 92.94 0.00e+00 679.00
IUUC-Pan-092433 Papio anubis 92.74 0.00e+00 640.00
IUUC-Psi-092940 Pelodiscus sinensis 87.19 0.00e+00 649.00
IUUC-Pma-094657 Petromyzon marinus 63.26 2.00e-122 431.00
IUUC-Ppa-095161 Physcomitrella patens 25.67 1.00e-09 57.80
IUUC-Pfo-096876 Poecilia formosa 75.27 3.00e-157 547.00
IUUC-Pab-097667 Pongo abelii 81.02 3.00e-153 534.00
IUUC-Pca-100102 Procavia capensis 86.68 0.00e+00 648.00
IUUC-Pva-102731 Pteropus vampyrus 85.05 3.00e-175 607.00
IUUC-Pgr-103312 Puccinia graminis 24.37 9.00e-15 75.50
IUUC-Rno-105425 Rattus norvegicus 97.55 0.00e+00 709.00
IUUC-Sha-106675 Sarcophilus harrisii 90.36 0.00e+00 674.00
IUUC-Ssc-115548 Sus scrofa 93.50 0.00e+00 663.00
IUUC-Tru-117979 Takifugu rubripes 76.49 9.00e-161 559.00
IUUC-Tni-120585 Tetraodon nigroviridis 75.61 4.00e-159 553.00
IUUC-Ttr-128449 Tursiops truncatus 93.22 0.00e+00 633.00
IUUC-Xtr-131935 Xenopus tropicalis 80.43 7.00e-165 573.00
Created Date 25-Jun-2017

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