iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0044323	FBtr0079537	FBpp0079159
FBgn0044323	FBtr0333096	FBpp0305309
FBgn0044323	FBtr0306001	FBpp0297143
FBgn0044323	FBtr0306000	FBpp0297142

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-31	107.1	674	711
UBD/Beta-Prp	2.60e-48	164.7	533	747

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           H ++vt+la   ++ +l+sGs+D++i++W+l+  ++++
   Q: 674  HLEPVTSLAVdaHGLYLLSGSHDCSIRLWNLDNKTCVQ 711
           999*******975599***************9999987 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvw.dlstgkcvhtlkghedsvl..slsfspsg.dklvsGshdrtirvwdletgqclee......t 132
             +l+gh+++v+ ++  ++   +v++s D+t+k+w ++++ + ++t+++ e++ +  s++f ++  d++v++ +     v+d+etg+ +        +
   Q: 533  SGTLEGHTDAVWGLTTMQS--NIVSCSADGTVKLWsPYNKEPLLRTYTASEAEGVpsSVDFVRNEvDHIVVAYNSAHCIVYDTETGKQVVRleaaqeM 628
           6899************999..5*************8899999999**97666543227*****888************************99999988 PP
   S: 133  lsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnght....dnvk 226
             ++ +++n vv+hp+  + ++++ Dr +r+Wd  +g+l++ +   h ++v+sl++d  g +l+sgs+d +++lw+l +++cv++ ++h+    + + 
   Q: 629  SGNTGKFINKVVSHPTLPITITAHEDRHIRFWDNTSGTLVHSMVA-HLEPVTSLAVDAHGLYLLSGSHDCSIRLWNLDNKTCVQEITAHRkkfdESIF 725
           888889*********99**************************98.********************************************88888899 PP
   S: 227  svrfspnderlvsgssDgsiri 248
           +v+f+  + +++s+++Dg  ++
   Q: 726  DVAFHATKPYIASAGADGLAKV 747
           9****************98776 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MGTNSGATAG INNKPVGGAT GAGVLVGGGV GGANSSIGGV LSNSLGGGGS GGLSISGLNA 60
GGQNANVGGM GNVGGDDGGN GMVGGGVNNQ QATTPQYTIP GILHFIQHEW SRFELERSQW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGTATTTTT TATCGTTATC GGCGCGGTCA CGCTGCTAAG AATTACATTA CGCGTGAATA 60
CCAATGAAAA TTAAGAGAGA AATTGCAAAA CACAGCCAAG CGGTGCAATA AATCGCAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0808--Transferase
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0072686--C:mitotic spindle
GO:0005634--C:nucleus
GO:0016301--F:kinase activity
GO:0007391--P:dorsal closure
GO:0042332--P:gravitaxis
GO:0007254--P:JNK cascade
GO:0006909--P:phagocytosis
GO:0070374--P:positive regulation of ERK1 and ERK2 cascade
GO:0046330--P:positive regulation of JNK cascade
GO:0046579--P:positive regulation of Ras protein signal transduction
GO:0051726--P:regulation of cell cycle
GO:2000736--P:regulation of stem cell differentiation

KEGG

dme:Dmel_CG7392

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002046	Ailuropoda melanoleuca	63.51	2.00e-140	492.00
IUUC-Apl-003472	Anas platyrhynchos	64.07	4.00e-141	494.00
IUUC-Aca-005286	Anolis carolinensis	62.95	8.00e-139	486.00
IUUC-Acl-008170	Aspergillus clavatus	24.64	5.00e-32	132.00
IUUC-Afl-008585	Aspergillus flavus	26.48	5.00e-37	148.00
IUUC-Afu-009096	Aspergillus fumigatus	27.72	4.00e-14	72.40
IUUC-Ani-009405	Aspergillus nidulans	29.67	1.00e-38	154.00
IUUC-Ang-009868	Aspergillus niger	32.10	1.00e-15	77.80
IUUC-Aor-009982	Aspergillus oryzae	26.48	6.00e-37	148.00
IUUC-Ate-010457	Aspergillus terreus	31.61	9.00e-20	91.70
IUUC-Ame-011915	Astyanax mexicanus	47.99	4.00e-160	557.00
IUUC-Bgr-012143	Blumeria graminis	26.16	3.00e-41	162.00
IUUC-Bta-012797	Bos taurus	63.51	4.00e-140	491.00
IUUC-Bci-013742	Botrytis cinerea	26.08	2.00e-41	163.00
IUUC-Cel-018443	Caenorhabditis elegans	51.98	2.00e-103	369.00
IUUC-Cja-018786	Callithrix jacchus	62.40	4.00e-138	484.00
IUUC-Cfa-021098	Canis familiaris	63.79	1.00e-140	493.00
IUUC-Cpo-022102	Cavia porcellus	54.07	1.00e-106	380.00
IUUC-Csa-023969	Chlorocebus sabaeus	54.45	1.00e-106	380.00
IUUC-Cho-024338	Choloepus hoffmanni	56.82	7.00e-120	424.00
IUUC-Cin-025167	Ciona intestinalis	56.80	2.00e-111	395.00
IUUC-Csv-026143	Ciona savignyi	55.22	2.00e-114	405.00
IUUC-Cgl-026487	Colletotrichum gloeosporioides	26.60	7.00e-35	141.00
IUUC-Cne-026783	Cryptococcus neoformans	34.81	5.00e-56	211.00
IUUC-Dre-027566	Danio rerio	50.79	0.00e+00	652.00
IUUC-Dno-029926	Dasypus novemcinctus	62.95	2.00e-139	489.00
IUUC-Dor-031032	Dipodomys ordii	44.40	1.00e-136	479.00
IUUC-Dse-031486	Dothistroma septosporum	27.06	1.00e-42	167.00
IUUC-Ete-032770	Echinops telfairi	45.03	6.00e-161	560.00
IUUC-Eca-033309	Equus caballus	62.50	3.00e-138	484.00
IUUC-Eeu-034953	Erinaceus europaeus	61.39	3.00e-133	468.00
IUUC-Fca-035719	Felis catus	63.23	4.00e-140	491.00
IUUC-Fal-037408	Ficedula albicollis	63.79	2.00e-140	491.00
IUUC-Fox-037678	Fusarium oxysporum	25.84	2.00e-39	156.00
IUUC-Fso-038364	Fusarium solani	26.65	4.00e-41	162.00
IUUC-Gmo-039653	Gadus morhua	54.50	3.00e-117	415.00
IUUC-Ggr-039846	Gaeumannomyces graminis	26.02	8.00e-38	150.00
IUUC-Gga-041218	Gallus gallus	64.07	4.00e-141	494.00
IUUC-Gac-042142	Gasterosteus aculeatus	49.52	0.00e+00	642.00
IUUC-Ggo-045607	Gorilla gorilla	63.79	1.00e-140	492.00
IUUC-Hsa-045717	Homo sapiens	63.51	2.00e-140	492.00
IUUC-Itr-048177	Ictidomys tridecemlineatus	62.29	1.00e-136	479.00
IUUC-Lch-050441	Latimeria chalumnae	61.58	7.00e-142	496.00
IUUC-Loc-052193	Lepisosteus oculatus	62.67	6.00e-140	490.00
IUUC-Lma-053183	Leptosphaeria maculans	26.38	2.00e-40	160.00
IUUC-Laf-053964	Loxodonta africana	63.79	6.00e-138	484.00
IUUC-Mcc-055737	Macaca mulatta	42.84	5.00e-135	474.00
IUUC-Meu-055946	Macropus eugenii	54.88	3.00e-99	355.00
IUUC-Mor-057148	Magnaporthe oryzae	24.94	3.00e-32	132.00
IUUC-Mpo-057337	Magnaporthe poae	27.23	1.00e-32	134.00
IUUC-Mla-058988	Melampsora laricipopulina	35.05	5.00e-64	238.00
IUUC-Mga-059885	Meleagris gallopavo	66.87	3.00e-139	486.00
IUUC-Mmr-061084	Microcebus murinus	63.23	6.00e-140	490.00
IUUC-Mdo-063016	Monodelphis domestica	63.23	9.00e-140	490.00
IUUC-Mmu-063914	Mus musculus	62.95	5.00e-139	487.00
IUUC-Mpu-066348	Mustela putorius furo	63.79	3.00e-140	491.00
IUUC-Mlu-067303	Myotis lucifugus	63.43	1.00e-133	469.00
IUUC-Nfi-068560	Neosartorya fischeri	25.30	2.00e-30	127.00
IUUC-Ncr-068831	Neurospora crassa	25.75	5.00e-36	145.00
IUUC-Nle-070032	Nomascus leucogenys	63.51	4.00e-140	491.00
IUUC-Opr-070496	Ochotona princeps	61.14	5.00e-124	437.00
IUUC-Ont-072075	Oreochromis niloticus	61.66	7.00e-137	480.00
IUUC-Oan-072822	Ornithorhynchus anatinus	64.07	2.00e-140	491.00
IUUC-Ocu-073876	Oryctolagus cuniculus	63.23	1.00e-139	489.00
IUUC-Ola-086321	Oryzias latipes	59.78	4.00e-133	468.00
IUUC-Oga-088045	Otolemur garnettii	63.51	2.00e-140	491.00
IUUC-Oar-089737	Ovis aries	63.06	2.00e-139	488.00
IUUC-Ptr-090871	Pan troglodytes	63.79	5.00e-141	493.00
IUUC-Pan-092139	Papio anubis	63.33	6.00e-139	487.00
IUUC-Psi-093424	Pelodiscus sinensis	62.95	2.00e-138	485.00
IUUC-Pma-094286	Petromyzon marinus	61.38	1.00e-133	469.00
IUUC-Pno-094905	Phaeosphaeria nodorum	29.18	2.00e-36	147.00
IUUC-Pfo-097042	Poecilia formosa	62.40	6.00e-136	477.00
IUUC-Pab-098626	Pongo abelii	63.86	7.00e-144	503.00
IUUC-Pca-101047	Procavia capensis	54.91	9.00e-99	353.00
IUUC-Pva-102823	Pteropus vampyrus	54.25	1.00e-107	383.00
IUUC-Pgr-103483	Puccinia graminis	33.92	1.00e-56	214.00
IUUC-Ptt-103828	Puccinia triticina	32.35	2.00e-44	173.00
IUUC-Pte-104374	Pyrenophora teres	26.24	6.00e-35	142.00
IUUC-Pyt-104568	Pyrenophora triticirepentis	26.83	3.00e-40	159.00
IUUC-Rno-105999	Rattus norvegicus	62.95	3.00e-138	484.00
IUUC-Sha-106786	Sarcophilus harrisii	63.23	9.00e-140	489.00
IUUC-Spo-108015	Schizosaccharomyces pombe	28.57	1.00e-16	80.50
IUUC-Ssl-108495	Sclerotinia sclerotiorum	26.30	3.00e-41	162.00
IUUC-Sar-113296	Sorex araneus	52.35	2.00e-83	302.00
IUUC-Sre-115115	Sporisorium reilianum	35.82	1.00e-68	253.00
IUUC-Ssc-115280	Sus scrofa	61.67	4.00e-133	468.00
IUUC-Tgu-116759	Taeniopygia guttata	62.22	3.00e-129	454.00
IUUC-Tru-118134	Takifugu rubripes	50.87	0.00e+00	645.00
IUUC-Tsy-119356	Tarsius syrichta	63.86	6.00e-64	238.00
IUUC-Tni-120571	Tetraodon nigroviridis	61.39	3.00e-129	455.00
IUUC-Tre-122113	Trichoderma reesei	26.79	6.00e-41	161.00
IUUC-Tvi-122312	Trichoderma virens	25.39	6.00e-38	152.00
IUUC-Tme-126990	Tuber melanosporum	26.88	2.00e-40	160.00
IUUC-Tbe-128127	Tupaia belangeri	58.26	3.00e-105	374.00
IUUC-Ttr-128600	Tursiops truncatus	63.51	2.00e-140	491.00
IUUC-Uma-129659	Ustilago maydis	35.71	2.00e-69	256.00
IUUC-Vda-129673	Verticillium dahliae	26.43	1.00e-37	150.00
IUUC-Vpa-130294	Vicugna pacos	61.39	1.00e-133	469.00
IUUC-Xtr-132330	Xenopus tropicalis	63.86	2.00e-140	492.00
IUUC-Xma-133090	Xiphophorus maculatus	46.22	4.00e-155	540.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence