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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018361
Ensembl Protein ID W02D3.9.1
UniProt Accession O02482; P91912; UNC37_CAEEL
Genbank Protein ID AAB49459.1; AAB84234.1; AAB84235.1; CCD68992.1
Protein Name Transcription factor unc-37; Uncoordinated protein 37
Genbank Nucleotide ID U89245; AF001271; AF001272; FO081084
Gene Name unc-37; esg; W02D3.9
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00006773 W02D3.9.1 W02D3.9.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 4.10e-19 68.2 456 489
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           gH+d+ +cl++  d t l+sG+ D+++++WDl +
   Q: 456  GHQDGASCLDLsKDgTKLWSGGLDNSVRCWDLAQ 489
           8***********777****************865 PP
   
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Transcriptional corepressor that functions with the neural specificity gene unc-4 to govern motor neuron identity (PubMed:9165118). May function with transcription factor mls-1 to promote uterine muscle specification and formation (PubMed:21852953).
 Transcriptional corepressor that functions with the neural specificity gene unc-4 to govern motor neuron identity (PubMed:9165118). May function with transcription factor mls-1 to promote uterine muscle specification and formation (PubMed:21852953).
Protein Sequence
(Fasta)
MKASYLETLD RIKDEHAEMS KHVNQQRSDI EKVALEKENM NRSYMTYAEV SNTLRSDLRK 60
AEEINKRLQE FIMQSLAPQL SQDNQANCLA ALEAFKTASP RENGNGAPAL PPGFPPGAAG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018361|E3,WD_repeat|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTAATTTTC AGTAAAAATG AAGGCATCGT ATCTGGAAAC CCTCGATCGA ATCAAAGACG 60
AGCATGCGGA AATGTCGAAG CATGTCAACC AGCAACGAGT AAGCTTAATT TTGTAAGAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018361|E3,WD_repeat|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat
Interpro

IPR005617--Groucho/TLE_N
IPR009146--Groucho_enhance
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF03920--TLE_N
PF00400--WD40
PRINTS

PR01850--GROUCHOFAMLY
SMART

SM00320--WD40
Gene Ontology

GO:0005634--C:nucleus
GO:0003714--F:transcription corepressor activity
GO:0008134--F:transcription factor binding
GO:0007268--P:chemical synaptic transmission
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0050770--P:regulation of axonogenesis
GO:0001505--P:regulation of neurotransmitter levels
GO:0050803--P:regulation of synapse structure or activity
GO:0006351--P:transcription, DNA-templated
KEGG cel:CELE_W02D3.9
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001359 Ailuropoda melanoleuca 58.71 6.00e-126 443.00
IUUC-Apl-003594 Anas platyrhynchos 59.41 2.00e-122 432.00
IUUC-Aca-005279 Anolis carolinensis 58.43 3.00e-125 441.00
IUUC-Ame-010724 Astyanax mexicanus 58.15 1.00e-123 436.00
IUUC-Bta-012646 Bos taurus 58.71 3.00e-126 444.00
IUUC-Cja-019079 Callithrix jacchus 58.71 5.00e-126 443.00
IUUC-Cfa-020987 Canis familiaris 58.71 5.00e-126 444.00
IUUC-Cpo-021606 Cavia porcellus 55.27 3.00e-126 444.00
IUUC-Csa-023445 Chlorocebus sabaeus 58.71 6.00e-126 443.00
IUUC-Cho-024590 Choloepus hoffmanni 60.30 2.00e-123 435.00
IUUC-Cin-025767 Ciona intestinalis 58.45 3.00e-123 434.00
IUUC-Csv-026174 Ciona savignyi 60.30 2.00e-115 408.00
IUUC-Dre-028595 Danio rerio 58.43 5.00e-124 437.00
IUUC-Dno-029011 Dasypus novemcinctus 59.41 1.00e-122 432.00
IUUC-Dor-030533 Dipodomys ordii 58.71 6.00e-125 440.00
IUUC-Dme-031576 Drosophila melanogaster 56.06 1.00e-119 422.00
IUUC-Ete-032533 Echinops telfairi 59.41 3.00e-122 431.00
IUUC-Eca-034397 Equus caballus 58.43 8.00e-125 439.00
IUUC-Eeu-034666 Erinaceus europaeus 59.41 4.00e-122 431.00
IUUC-Fca-036030 Felis catus 58.71 4.00e-126 444.00
IUUC-Fal-037460 Ficedula albicollis 58.43 2.00e-125 441.00
IUUC-Gmo-038805 Gadus morhua 57.98 2.00e-123 435.00
IUUC-Gga-040416 Gallus gallus 58.43 3.00e-125 441.00
IUUC-Gac-041924 Gasterosteus aculeatus 58.43 3.00e-124 437.00
IUUC-Ggo-045633 Gorilla gorilla 58.71 2.00e-125 442.00
IUUC-Hsa-046461 Homo sapiens 58.71 1.00e-125 442.00
IUUC-Itr-048974 Ictidomys tridecemlineatus 58.71 6.00e-126 443.00
IUUC-Lch-049943 Latimeria chalumnae 57.87 2.00e-124 438.00
IUUC-Loc-052835 Lepisosteus oculatus 58.15 3.00e-124 437.00
IUUC-Laf-053425 Loxodonta africana 58.71 6.00e-126 443.00
IUUC-Mcc-055766 Macaca mulatta 58.71 1.00e-125 442.00
IUUC-Meu-056209 Macropus eugenii 58.43 1.00e-123 436.00
IUUC-Mga-059792 Meleagris gallopavo 56.39 8.00e-108 383.00
IUUC-Mmr-061317 Microcebus murinus 58.71 2.00e-125 442.00
IUUC-Mdo-062956 Monodelphis domestica 58.43 9.00e-124 436.00
IUUC-Mmu-063576 Mus musculus 58.71 7.00e-126 443.00
IUUC-Mpu-066410 Mustela putorius furo 58.71 4.00e-126 444.00
IUUC-Mlu-067456 Myotis lucifugus 58.71 6.00e-126 443.00
IUUC-Nle-069495 Nomascus leucogenys 58.71 7.00e-126 443.00
IUUC-Opr-070645 Ochotona princeps 58.71 7.00e-126 443.00
IUUC-Ont-071419 Oreochromis niloticus 58.15 1.00e-124 439.00
IUUC-Oan-072842 Ornithorhynchus anatinus 60.66 7.00e-123 433.00
IUUC-Ocu-074453 Oryctolagus cuniculus 58.71 6.00e-126 443.00
IUUC-Ola-087090 Oryzias latipes 58.15 1.00e-124 439.00
IUUC-Oga-087939 Otolemur garnettii 58.71 5.00e-126 443.00
IUUC-Oar-090347 Ovis aries 58.71 3.00e-126 444.00
IUUC-Ptr-091048 Pan troglodytes 58.71 6.00e-126 443.00
IUUC-Pan-091973 Papio anubis 58.71 5.00e-126 443.00
IUUC-Psi-093586 Pelodiscus sinensis 58.43 2.00e-125 442.00
IUUC-Pma-094546 Petromyzon marinus 57.42 1.00e-122 432.00
IUUC-Pfo-097518 Poecilia formosa 58.15 2.00e-124 438.00
IUUC-Pab-097539 Pongo abelii 58.71 2.00e-125 442.00
IUUC-Pca-101137 Procavia capensis 58.43 2.00e-124 438.00
IUUC-Pva-103037 Pteropus vampyrus 58.71 5.00e-126 444.00
IUUC-Rno-104864 Rattus norvegicus 58.15 1.00e-122 432.00
IUUC-Sha-106486 Sarcophilus harrisii 58.71 2.00e-125 441.00
IUUC-Sar-113414 Sorex araneus 57.40 2.00e-109 388.00
IUUC-Ssc-116408 Sus scrofa 58.71 3.00e-126 444.00
IUUC-Tgu-117068 Taeniopygia guttata 58.43 3.00e-125 441.00
IUUC-Tru-118782 Takifugu rubripes 57.58 5.00e-124 437.00
IUUC-Tsy-118884 Tarsius syrichta 58.71 7.00e-125 439.00
IUUC-Tni-120404 Tetraodon nigroviridis 55.06 3.00e-125 441.00
IUUC-Tbe-127881 Tupaia belangeri 59.41 3.00e-122 431.00
IUUC-Ttr-129285 Tursiops truncatus 58.71 6.00e-126 443.00
IUUC-Vpa-130577 Vicugna pacos 71.97 3.00e-68 252.00
IUUC-Xtr-132704 Xenopus tropicalis 57.18 2.00e-123 435.00
Created Date 25-Jun-2017

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