iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000027012.6	ENSRNOT00000083467.1	ENSRNOP00000068778.1
ENSRNOG00000027012.6	ENSRNOT00000029615.4	ENSRNOP00000038767.4

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-23	84.1	32	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavspre.....llkalkkeaee 83
           Gl+N   +N+C++NS+LQ+L+++  +r+ + + +++k+  +       ++ ++l+ +f++++ +++++v p++     l k++++e+ +
   Q: 32   GLSNEpgQNSCFLNSALQVLWHLDIFRRSFRQLTSHKCMGD------SCIFCALKGIFKQFQ-CSSEKVLPSDtlrsaLAKTFQDEQ-R 112
           88887668************************999**9986......69************5.555555555543333555555444.5 PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           f+     Da E+++ ll +++ ++                    de +e+  +  +++ ++ F ++l +q++c +c+ +s    pf+++
   Q: 113  FQLGIMDDAAECFENLLMRIHFHI-------------------ADETKEDICTAPHCISHQKFAMTLFEQCVCTSCGATSDPL-PFIQM 181
           99**********************...................34556778999************************99766.9**** PP
   S: 173  slpvpgkeetkke.............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
              ++  + +++               + ++L++ ++   l++      ++c ++    +++ + + P+++++ L +   s + +  e 
   Q: 182  VHYISTTSLCNQAicmlekrekpspgMFGELLQNASTMGDLRD----CPSNCGERI-RIRRVLM-NAPQIITIGLVWD--SDHSDLAED 262
           *****99999888999999999777777777777777777774....445555555.5666655.56**********9..333344444 PP
   S: 249  inkkvefpleLdlsp..fctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...st 329
           +  ++ +   L+l    f ++ ++  k+++ Y L+++++++G     HY ++  ++k + W++fdD +V+e+  k+++v++++     +
   Q: 263  VIHSLGTC--LKLGDlfFRVT-DDRAKQSELY-LVGMICYYG----KHYSTFFFQTKIRkWMYFDDAHVKEIgpKWKDVVTKCIkghYQ 343
           44444444..55555213333.3333335555.*********....9*****99987767************76689998865555555 PP
   S: 330  aYvlfY 335
           + +l+Y
   Q: 344  PLLLLY 349
           556666 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSWKRNYFSG GRGSVQGMFA PRSSMSIAPS KGLSNEPGQN SCFLNSALQV LWHLDIFRRS 60
FRQLTSHKCM GDSCIFCALK GIFKQFQCSS EKVLPSDTLR SALAKTFQDE QRFQLGIMDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTGTGTGTG TTAGTGTGTG TGTGCGCGCG CGCCTGTGTG TGTGTGTGTG TGTGTGTGTG 60
TGTGTTAGTG TGTGTGTGCG CGCGCGCCTG TGATTTGCTT CCTATTTTGG TCTCGAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000820	Aegilops tauschii	31.36	1.00e-18	87.40
IUUC-Aml-001414	Ailuropoda melanoleuca	77.35	0.00e+00	2257.00
IUUC-Atr-002451	Amborella trichopoda	30.41	5.00e-37	150.00
IUUC-Apl-004044	Anas platyrhynchos	76.89	0.00e+00	1191.00
IUUC-Aca-004351	Anolis carolinensis	54.61	0.00e+00	1425.00
IUUC-Aly-005468	Arabidopsis lyrata	32.23	5.00e-42	167.00
IUUC-Ath-007147	Arabidopsis thaliana	32.27	3.00e-41	164.00
IUUC-Ame-011525	Astyanax mexicanus	60.78	0.00e+00	968.00
IUUC-Bta-013344	Bos taurus	75.24	0.00e+00	2226.00
IUUC-Bdi-015058	Brachypodium distachyon	32.41	3.00e-41	164.00
IUUC-Bol-015670	Brassica oleracea	31.78	6.00e-39	155.00
IUUC-Bra-016731	Brassica rapa	32.07	9.00e-41	163.00
IUUC-Cja-018724	Callithrix jacchus	76.34	0.00e+00	2200.00
IUUC-Cfa-021222	Canis familiaris	76.69	0.00e+00	2309.00
IUUC-Cpo-021795	Cavia porcellus	78.99	0.00e+00	1951.00
IUUC-Cre-022697	Chlamydomonas reinhardtii	24.08	2.00e-17	86.70
IUUC-Csa-023262	Chlorocebus sabaeus	77.12	0.00e+00	2261.00
IUUC-Cho-024422	Choloepus hoffmanni	75.66	0.00e+00	1801.00
IUUC-Cin-025752	Ciona intestinalis	69.42	4.00e-49	186.00
IUUC-Csv-026063	Ciona savignyi	56.40	5.00e-113	400.00
IUUC-Dre-028046	Danio rerio	62.54	0.00e+00	942.00
IUUC-Dno-029417	Dasypus novemcinctus	76.59	0.00e+00	2164.00
IUUC-Dor-030653	Dipodomys ordii	64.60	0.00e+00	866.00
IUUC-Dme-032071	Drosophila melanogaster	54.43	2.00e-105	377.00
IUUC-Ete-032692	Echinops telfairi	56.60	0.00e+00	634.00
IUUC-Eca-033235	Equus caballus	78.93	0.00e+00	1966.00
IUUC-Eeu-034975	Erinaceus europaeus	55.34	0.00e+00	722.00
IUUC-Fca-036070	Felis catus	75.88	0.00e+00	2244.00
IUUC-Fal-037089	Ficedula albicollis	61.70	0.00e+00	1458.00
IUUC-Gmo-038653	Gadus morhua	73.63	1.00e-170	592.00
IUUC-Gga-041241	Gallus gallus	56.34	0.00e+00	1515.00
IUUC-Gac-042157	Gasterosteus aculeatus	80.46	0.00e+00	682.00
IUUC-Gma-043273	Glycine max	30.84	3.00e-37	151.00
IUUC-Ggo-045626	Gorilla gorilla	77.29	0.00e+00	2247.00
IUUC-Hsa-045767	Homo sapiens	77.52	0.00e+00	2251.00
IUUC-Hvu-047657	Hordeum vulgare	31.67	3.00e-42	167.00
IUUC-Itr-048187	Ictidomys tridecemlineatus	73.17	0.00e+00	2221.00
IUUC-Lch-049712	Latimeria chalumnae	86.23	0.00e+00	705.00
IUUC-Lpe-051572	Leersia perrieri	32.34	1.00e-39	159.00
IUUC-Loc-052615	Lepisosteus oculatus	64.41	0.00e+00	994.00
IUUC-Laf-054578	Loxodonta africana	69.35	0.00e+00	1375.00
IUUC-Mcc-054696	Macaca mulatta	77.24	0.00e+00	2236.00
IUUC-Meu-056841	Macropus eugenii	45.36	2.00e-144	508.00
IUUC-Mtr-058682	Medicago truncatula	29.11	5.00e-33	137.00
IUUC-Mga-059519	Meleagris gallopavo	45.35	0.00e+00	989.00
IUUC-Mmr-060701	Microcebus murinus	76.70	0.00e+00	2187.00
IUUC-Mdo-062433	Monodelphis domestica	62.69	0.00e+00	1741.00
IUUC-Mmu-063480	Mus musculus	86.50	0.00e+00	2658.00
IUUC-Mac-064469	Musa acuminata	32.61	6.00e-20	93.60
IUUC-Mpu-066404	Mustela putorius furo	76.61	0.00e+00	2321.00
IUUC-Mlu-067841	Myotis lucifugus	70.53	0.00e+00	1358.00
IUUC-Nle-070110	Nomascus leucogenys	79.86	0.00e+00	1964.00
IUUC-Opr-070676	Ochotona princeps	78.67	0.00e+00	1272.00
IUUC-Ont-072289	Oreochromis niloticus	61.81	0.00e+00	711.00
IUUC-Oan-073551	Ornithorhynchus anatinus	61.23	0.00e+00	1514.00
IUUC-Ocu-074729	Oryctolagus cuniculus	77.10	0.00e+00	2302.00
IUUC-Oba-075174	Oryza barthii	30.12	4.00e-34	140.00
IUUC-Obr-076268	Oryza brachyantha	31.98	5.00e-42	167.00
IUUC-Ogl-077138	Oryza glaberrima	31.47	2.00e-39	158.00
IUUC-Ogu-078705	Oryza glumaepatula	30.12	4.00e-34	140.00
IUUC-Oin-079125	Oryza indica	31.47	3.00e-39	158.00
IUUC-Olo-080872	Oryza longistaminata	30.12	4.00e-34	140.00
IUUC-Ome-081864	Oryza meridionalis	30.41	2.00e-33	139.00
IUUC-Oni-082109	Oryza nivara	30.12	4.00e-34	140.00
IUUC-Opu-083823	Oryza punctata	32.06	4.00e-40	160.00
IUUC-Oru-084310	Oryza rufipogon	30.12	5.00e-34	140.00
IUUC-Osa-085583	Oryza sativa	31.47	1.00e-38	154.00
IUUC-Ola-086742	Oryzias latipes	81.10	0.00e+00	645.00
IUUC-Oga-088920	Otolemur garnettii	81.01	0.00e+00	1982.00
IUUC-Oar-089644	Ovis aries	75.35	0.00e+00	2229.00
IUUC-Ptr-091530	Pan troglodytes	80.07	0.00e+00	1962.00
IUUC-Pan-092190	Papio anubis	86.33	0.00e+00	1511.00
IUUC-Psi-094022	Pelodiscus sinensis	78.62	0.00e+00	1310.00
IUUC-Pma-094745	Petromyzon marinus	59.89	3.00e-135	474.00
IUUC-Ppa-095930	Physcomitrella patens	29.12	4.00e-38	154.00
IUUC-Pfo-096072	Poecilia formosa	78.56	0.00e+00	690.00
IUUC-Pab-097979	Pongo abelii	80.18	0.00e+00	1892.00
IUUC-Pop-099539	Populus trichocarpa	31.79	6.00e-37	150.00
IUUC-Pca-101005	Procavia capensis	63.66	0.00e+00	1759.00
IUUC-Ppe-101918	Prunus persica	30.61	3.00e-38	154.00
IUUC-Pva-103125	Pteropus vampyrus	76.46	0.00e+00	2209.00
IUUC-Sha-107164	Sarcophilus harrisii	62.93	0.00e+00	1695.00
IUUC-Sit-110021	Setaria italica	31.96	6.00e-37	150.00
IUUC-Sly-110975	Solanum lycopersicum	30.64	6.00e-39	157.00
IUUC-Stu-112904	Solanum tuberosum	30.53	3.00e-37	151.00
IUUC-Sar-113423	Sorex araneus	53.72	0.00e+00	674.00
IUUC-Sbi-114345	Sorghum bicolor	33.14	1.00e-41	166.00
IUUC-Ssc-116206	Sus scrofa	75.45	0.00e+00	2180.00
IUUC-Tgu-116521	Taeniopygia guttata	92.15	0.00e+00	781.00
IUUC-Tru-118155	Takifugu rubripes	69.95	5.00e-171	593.00
IUUC-Tsy-118998	Tarsius syrichta	74.09	0.00e+00	1984.00
IUUC-Tni-120257	Tetraodon nigroviridis	79.85	0.00e+00	659.00
IUUC-Tca-121692	Theobroma cacao	31.58	7.00e-38	153.00
IUUC-Tae-125619	Triticum aestivum	31.94	6.00e-43	170.00
IUUC-Tur-126027	Triticum urartu	31.94	1.00e-42	169.00
IUUC-Ttr-128290	Tursiops truncatus	77.28	0.00e+00	1796.00
IUUC-Vpa-130213	Vicugna pacos	76.87	0.00e+00	1878.00
IUUC-Vvi-131652	Vitis vinifera	30.90	2.00e-38	155.00
IUUC-Xtr-131831	Xenopus tropicalis	69.58	0.00e+00	1207.00
IUUC-Xma-133409	Xiphophorus maculatus	58.46	0.00e+00	820.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence