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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064037
Ensembl Protein ID ENSMUSP00000003370.7
UniProt Accession F6UND7; F6UND7_MOUSE
Genbank Protein ID ENSMUSP00000003370
Protein Name Tyrosine-protein kinase
Genbank Nucleotide ID AL807380
Gene Name Hck
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000003283.14 ENSMUST00000003370.13 ENSMUSP00000003370.7
ENSMUSG00000003283.14 ENSMUST00000191431.7 ENSMUSP00000139988.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 8.50e-16 58.8 78 135
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +  v +lydyea + ++L+++kGd++ v+   e+ ++W+k+ + +++k+G +P+n+v++++
   Q: 78   DTIVVALYDYEAIHREDLSFQKGDQMVVL---EEAGEWWKARSLATKKEGYIPSNYVARVN 135
           56899************************...999************************97 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
LGGRSSCEDP GCPRSEGRAP RMGCVKSRFL RDGSKASKTE PSANQKGPVY VPDPTSSSKL 60
GPNNSNSMPP GFVEGSEDTI VVALYDYEAI HREDLSFQKG DQMVVLEEAG EWWKARSLAT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064037|UBD,SH3|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATCACCCAGG GTGCGGCTAA GGCGCCCAGA TGGCCAGTGA GCGCCACTGG GTTGCGGCTC 60
CCAGCTTGCA CTCCCCGCGG CGGCTCTCAG ACGGGTGGGA GGGGACCAAA GTCGCCCGTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064037|UBD,SH3|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE
SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0005654--C:nucleoplasm
GO:0005886--C:plasma membrane
GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000140 Aegilops tauschii 31.01 7.00e-22 99.80
IUUC-Aml-001284 Ailuropoda melanoleuca 87.83 0.00e+00 969.00
IUUC-Apl-003285 Anas platyrhynchos 77.54 0.00e+00 815.00
IUUC-Aca-004724 Anolis carolinensis 76.62 0.00e+00 791.00
IUUC-Ame-011954 Astyanax mexicanus 74.70 0.00e+00 765.00
IUUC-Bta-013060 Bos taurus 90.08 0.00e+00 996.00
IUUC-Cja-019817 Callithrix jacchus 89.72 0.00e+00 931.00
IUUC-Cfa-020511 Canis familiaris 88.74 0.00e+00 983.00
IUUC-Cpo-022538 Cavia porcellus 90.10 0.00e+00 954.00
IUUC-Csa-024143 Chlorocebus sabaeus 90.10 0.00e+00 946.00
IUUC-Dre-028157 Danio rerio 74.40 0.00e+00 786.00
IUUC-Dno-029761 Dasypus novemcinctus 88.49 0.00e+00 936.00
IUUC-Eca-034090 Equus caballus 87.40 0.00e+00 963.00
IUUC-Fca-035937 Felis catus 86.07 0.00e+00 928.00
IUUC-Fal-036624 Ficedula albicollis 77.65 0.00e+00 809.00
IUUC-Gmo-039009 Gadus morhua 72.37 0.00e+00 759.00
IUUC-Gga-040296 Gallus gallus 75.45 0.00e+00 790.00
IUUC-Gac-042362 Gasterosteus aculeatus 72.58 0.00e+00 772.00
IUUC-Ggo-044570 Gorilla gorilla 89.54 0.00e+00 976.00
IUUC-Hsa-046378 Homo sapiens 89.73 0.00e+00 984.00
IUUC-Hvu-047855 Hordeum vulgare 31.01 3.00e-22 100.00
IUUC-Itr-048695 Ictidomys tridecemlineatus 89.71 0.00e+00 975.00
IUUC-Loc-052904 Lepisosteus oculatus 77.17 0.00e+00 823.00
IUUC-Laf-053654 Loxodonta africana 89.29 0.00e+00 952.00
IUUC-Mcc-055317 Macaca mulatta 90.48 0.00e+00 953.00
IUUC-Mga-060194 Meleagris gallopavo 81.07 0.00e+00 773.00
IUUC-Mmr-061510 Microcebus murinus 89.09 0.00e+00 945.00
IUUC-Mdo-062035 Monodelphis domestica 82.97 0.00e+00 889.00
IUUC-Mpu-066874 Mustela putorius furo 88.69 0.00e+00 946.00
IUUC-Mlu-068202 Myotis lucifugus 83.82 0.00e+00 895.00
IUUC-Nle-069222 Nomascus leucogenys 90.08 0.00e+00 943.00
IUUC-Opr-070705 Ochotona princeps 87.26 0.00e+00 971.00
IUUC-Ont-072347 Oreochromis niloticus 80.58 0.00e+00 760.00
IUUC-Ocu-074490 Oryctolagus cuniculus 88.07 0.00e+00 937.00
IUUC-Ola-086521 Oryzias latipes 78.19 0.00e+00 767.00
IUUC-Oga-088153 Otolemur garnettii 88.51 0.00e+00 937.00
IUUC-Oar-090184 Ovis aries 88.82 0.00e+00 962.00
IUUC-Ptr-090505 Pan troglodytes 85.93 0.00e+00 924.00
IUUC-Pan-092260 Papio anubis 90.28 0.00e+00 952.00
IUUC-Pma-094311 Petromyzon marinus 71.67 0.00e+00 735.00
IUUC-Pfo-096566 Poecilia formosa 74.75 0.00e+00 797.00
IUUC-Pva-103021 Pteropus vampyrus 89.88 0.00e+00 952.00
IUUC-Rno-105309 Rattus norvegicus 97.42 0.00e+00 1025.00
IUUC-Sha-107099 Sarcophilus harrisii 81.89 0.00e+00 878.00
IUUC-Tgu-116912 Taeniopygia guttata 76.77 0.00e+00 798.00
IUUC-Tru-118449 Takifugu rubripes 79.33 0.00e+00 751.00
IUUC-Tae-123706 Triticum aestivum 31.40 1.00e-22 101.00
IUUC-Tur-126022 Triticum urartu 31.40 2.00e-22 101.00
IUUC-Tbe-128144 Tupaia belangeri 85.78 0.00e+00 794.00
IUUC-Xma-133902 Xiphophorus maculatus 74.26 0.00e+00 787.00
Created Date 25-Jun-2017

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