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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063564
UUCD1 version UUC-MuM-00319
Ensembl Protein ID ENSMUSP00000019220.8
UniProt Accession P58404; E9QKX6; Q68EF5; STRN4_MOUSE
Genbank Protein ID AAL07439.1; AAH04025.1; AAH80283.1
Protein Name Striatin-4; Zinedin
Genbank Nucleotide ID AF414080; AC148981; BC080283
Gene Name Strn4; Zin
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000030374.15 ENSMUST00000019220.15 ENSMUSP00000019220.8
ENSMUSG00000030374.15 ENSMUST00000108495.8 ENSMUSP00000104135.1
ENSMUSG00000030374.15 ENSMUST00000184280.7 ENSMUSP00000139307.1
ENSMUSG00000030374.15 ENSMUST00000184708.7 ENSMUSP00000139171.1
ENSMUSG00000030374.15 ENSMUST00000184694.1 ENSMUSP00000139113.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 4.50e-27 94.1 549 582
UBD/Beta-Prp 6.70e-47 161.2 597 759
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           gH d v++laf ++  +l+s+s Dgt+++WD+++
   Q: 549  GHGDAVWGLAFsPTsQRLASCSADGTVRIWDPSS 582
           8***********7779***************765 PP
   

   UBD/Beta-Prp
   S: 10   ksvitcvkf.spdksllatgsrdgtikvwdvttgkllrsl.sgheae...vtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkgh 93
            +  t+v+f s +  ++++++r+g + ++d++ g++l +l s  +++   +++v  +p++++ +t+++Dr i+  d +tgk vh++ +h
   Q: 597  HGIPTSVAFtSTEPAHVVASFRSGDTVLYDLEAGSALLTLeSRGSSGpaqINQVVSHPSQPLTITAHDDRGIRFLDNRTGKSVHSMVAH 685
           56778999*9999999********************77775444333455*************************************** PP
   S: 94   edsvlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlW 164
            d v++l+++p+g +l sGshd  +r+w l++++c++e     ++h++++  v+ hp++ l++s+++D   +++
   Q: 686  LDAVTCLAVDPNGVFLMSGSHDCSLRLWSLDNKTCVQEitaHRKKHEEAIHAVACHPSKALIASAGADALAKVF 759
           **************************************999999************************988887 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Interacts with CTTNBP2; this interaction may regulate dendritic spine distribution of STRN4. Activation of glutamate receptors weakens the interaction with CTTNBP2 (By similarity). Interacts with CTTNBP2NL (By similarity).
 Interacts with CTTNBP2; this interaction may regulate dendritic spine distribution of STRN4. Activation of glutamate receptors weakens the interaction with CTTNBP2 (By similarity). Interacts with CTTNBP2NL (By similarity).
Protein Sequence
(Fasta)
MMEERAAAAV ASAASSCRPL GSGTAPNPTA AAPASSPAPG PGPVGKGGGG GGSPGPTAGP 60
EPLSLPGILH FIQHEWARFE AEKARWEAER AELQAQVAFL QGERKGQENL KTDLVRRIKM 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063564|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTGGATAGGG TTATTATGAC AACCGACTTC CTCTGGTCAG AGCCCACTCC CCACCCCAGG 60
TCGTCTTTTT TGTTTTTTGT TTTTTTTTTC TTCACTAAGT GAAAGAGATG GGGGTGTATT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063564|E3,WD_repeat;UBD,Beta-Prp|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0112--Calmodulin-binding
KW-0966--Cell projection
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08232--Striatin
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0043197--C:dendritic spine
GO:0016020--C:membrane
GO:0043234--C:protein complex
GO:0000159--C:protein phosphatase type 2A complex
GO:0070016--F:armadillo repeat domain binding
GO:0032403--F:protein complex binding
GO:0051721--F:protein phosphatase 2A binding
KEGG mmu:97387
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001946 Ailuropoda melanoleuca 80.03 0.00e+00 1002.00
IUUC-Aca-004552 Anolis carolinensis 78.56 0.00e+00 1011.00
IUUC-Acl-008170 Aspergillus clavatus 26.51 1.00e-26 115.00
IUUC-Ate-010457 Aspergillus terreus 26.27 5.00e-27 116.00
IUUC-Bta-012550 Bos taurus 92.08 0.00e+00 1061.00
IUUC-Cja-018978 Callithrix jacchus 93.23 0.00e+00 956.00
IUUC-Cfa-020268 Canis familiaris 94.74 0.00e+00 1085.00
IUUC-Cpo-022102 Cavia porcellus 95.09 0.00e+00 1110.00
IUUC-Csa-023969 Chlorocebus sabaeus 94.74 0.00e+00 1155.00
IUUC-Dre-027638 Danio rerio 61.29 0.00e+00 814.00
IUUC-Dno-029256 Dasypus novemcinctus 96.16 0.00e+00 667.00
IUUC-Dor-031032 Dipodomys ordii 94.86 0.00e+00 1118.00
IUUC-Eca-033515 Equus caballus 94.90 0.00e+00 1121.00
IUUC-Eeu-035033 Erinaceus europaeus 79.34 6.00e-128 451.00
IUUC-Fca-035749 Felis catus 92.97 0.00e+00 1060.00
IUUC-Gmo-039274 Gadus morhua 60.67 0.00e+00 780.00
IUUC-Gac-042099 Gasterosteus aculeatus 59.94 0.00e+00 790.00
IUUC-Ggo-045406 Gorilla gorilla 95.86 0.00e+00 1134.00
IUUC-Hsa-046341 Homo sapiens 95.13 0.00e+00 1136.00
IUUC-Itr-048200 Ictidomys tridecemlineatus 96.70 0.00e+00 1131.00
IUUC-Lch-049604 Latimeria chalumnae 64.67 0.00e+00 826.00
IUUC-Loc-052671 Lepisosteus oculatus 60.99 0.00e+00 817.00
IUUC-Laf-054531 Loxodonta africana 95.89 0.00e+00 1031.00
IUUC-Mcc-055737 Macaca mulatta 89.86 0.00e+00 1094.00
IUUC-Meu-056845 Macropus eugenii 86.55 0.00e+00 1026.00
IUUC-Mmr-061153 Microcebus murinus 95.39 0.00e+00 1169.00
IUUC-Mdo-062739 Monodelphis domestica 81.48 0.00e+00 966.00
IUUC-Mpu-065794 Mustela putorius furo 92.81 0.00e+00 1014.00
IUUC-Nfi-068560 Neosartorya fischeri 26.02 4.00e-26 113.00
IUUC-Nle-069587 Nomascus leucogenys 86.49 0.00e+00 1001.00
IUUC-Opr-071219 Ochotona princeps 73.95 0.00e+00 815.00
IUUC-Ont-071528 Oreochromis niloticus 56.29 0.00e+00 764.00
IUUC-Ocu-073953 Oryctolagus cuniculus 91.27 0.00e+00 954.00
IUUC-Ola-086888 Oryzias latipes 62.62 4.00e-157 548.00
IUUC-Oga-088280 Otolemur garnettii 96.55 0.00e+00 1150.00
IUUC-Oar-090381 Ovis aries 87.88 0.00e+00 982.00
IUUC-Ptr-090704 Pan troglodytes 92.11 0.00e+00 1077.00
IUUC-Pan-092058 Papio anubis 94.74 0.00e+00 1154.00
IUUC-Psi-093535 Pelodiscus sinensis 72.27 0.00e+00 695.00
IUUC-Pfo-096556 Poecilia formosa 60.03 0.00e+00 791.00
IUUC-Pab-098573 Pongo abelii 95.95 0.00e+00 1110.00
IUUC-Pca-100746 Procavia capensis 90.69 0.00e+00 997.00
IUUC-Pva-102823 Pteropus vampyrus 94.61 0.00e+00 1109.00
IUUC-Rno-105418 Rattus norvegicus 98.57 0.00e+00 1167.00
IUUC-Ssc-116050 Sus scrofa 94.00 0.00e+00 892.00
IUUC-Tru-117971 Takifugu rubripes 61.12 0.00e+00 805.00
IUUC-Tni-120522 Tetraodon nigroviridis 62.18 0.00e+00 821.00
IUUC-Tbe-128127 Tupaia belangeri 94.96 0.00e+00 639.00
IUUC-Ttr-128911 Tursiops truncatus 87.99 0.00e+00 1024.00
IUUC-Vda-129673 Verticillium dahliae 25.36 3.00e-28 120.00
Created Date 25-Jun-2017

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