iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
miRNAMap	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.60e-12	45.2	252	275

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 7    tclafsdtllvsGsdDgtikvWDlrtg 33
            c++   +ll+++s D t+k+WDlr+ 
   Q: 252  PCCD---WLLATASIDQTVKIWDLRQI 275
           3444...5***************9975 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MAPKKCPETQ KSPDVAVLLK SKSRRSPQEL EPEAKKLFVQ GPVSSRKCES CCLLAELSSL 60
QIPPRSSSIV RDLYQQKLGK ATWPSLQQGL QKSFLHSLAS YRVFQKAAPF DRRTTSLAWH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAGTAAAG CAGCCCTAGG AGAGTTTGGC GCGAAGTTGT CTGTGCCAAG CTACCTGCGA 60
CGACGGCGCT CCTTCGTACG TAGTCCCTTC CTGTTTTTCT CCTTCGAGGC TTTTCAGGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR033312--DDB2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0030054--C:cell junction
GO:0031465--C:Cul4B-RING E3 ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0043234--C:protein complex
GO:0003684--F:damaged DNA binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0035518--P:histone H2A monoubiquitination
GO:0051865--P:protein autoubiquitination
GO:0000209--P:protein polyubiquitination
GO:0006290--P:pyrimidine dimer repair
GO:0070914--P:UV-damage excision repair

KEGG

rno:100362121

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000470	Aegilops tauschii	30.40	2.00e-32	133.00
IUUC-Aml-002203	Ailuropoda melanoleuca	80.42	0.00e+00	698.00
IUUC-Atr-002957	Amborella trichopoda	32.52	1.00e-36	147.00
IUUC-Apl-003832	Anas platyrhynchos	58.20	3.00e-120	425.00
IUUC-Aca-004358	Anolis carolinensis	53.35	1.00e-121	430.00
IUUC-Aly-006296	Arabidopsis lyrata	31.82	3.00e-37	149.00
IUUC-Ath-007115	Arabidopsis thaliana	31.27	7.00e-39	155.00
IUUC-Ame-010817	Astyanax mexicanus	53.09	9.00e-117	413.00
IUUC-Bta-012914	Bos taurus	79.86	0.00e+00	712.00
IUUC-Bdi-014261	Brachypodium distachyon	30.28	2.00e-31	130.00
IUUC-Bol-015317	Brassica oleracea	32.11	5.00e-37	149.00
IUUC-Bra-016848	Brassica rapa	32.01	3.00e-37	149.00
IUUC-Cja-018967	Callithrix jacchus	78.44	0.00e+00	683.00
IUUC-Cfa-021238	Canis familiaris	81.75	0.00e+00	679.00
IUUC-Cpo-022063	Cavia porcellus	75.24	0.00e+00	679.00
IUUC-Csa-023382	Chlorocebus sabaeus	77.96	0.00e+00	702.00
IUUC-Cho-024805	Choloepus hoffmanni	56.27	3.00e-85	308.00
IUUC-Dre-028732	Danio rerio	48.21	2.00e-103	369.00
IUUC-Dor-030461	Dipodomys ordii	77.13	1.00e-119	422.00
IUUC-Ete-033038	Echinops telfairi	70.49	2.00e-180	625.00
IUUC-Eca-033772	Equus caballus	81.03	0.00e+00	677.00
IUUC-Eeu-034662	Erinaceus europaeus	59.00	3.00e-62	232.00
IUUC-Fca-036095	Felis catus	80.52	0.00e+00	682.00
IUUC-Gmo-039683	Gadus morhua	47.63	3.00e-100	358.00
IUUC-Gga-040530	Gallus gallus	52.14	5.00e-121	427.00
IUUC-Gac-041517	Gasterosteus aculeatus	48.22	2.00e-96	345.00
IUUC-Gma-043378	Glycine max	31.67	2.00e-39	156.00
IUUC-Ggo-045364	Gorilla gorilla	79.15	0.00e+00	711.00
IUUC-Hsa-046354	Homo sapiens	78.91	0.00e+00	708.00
IUUC-Hvu-047151	Hordeum vulgare	30.82	3.00e-28	119.00
IUUC-Itr-048304	Ictidomys tridecemlineatus	83.05	0.00e+00	730.00
IUUC-Lpe-051256	Leersia perrieri	29.97	1.00e-30	127.00
IUUC-Loc-052398	Lepisosteus oculatus	53.45	2.00e-122	432.00
IUUC-Laf-053562	Loxodonta africana	80.19	0.00e+00	685.00
IUUC-Mcc-055197	Macaca mulatta	63.47	3.00e-154	537.00
IUUC-Meu-056151	Macropus eugenii	72.22	8.00e-113	399.00
IUUC-Mtr-057940	Medicago truncatula	30.03	2.00e-36	146.00
IUUC-Mga-059923	Meleagris gallopavo	54.46	6.00e-127	447.00
IUUC-Mmr-061465	Microcebus murinus	64.17	2.00e-150	525.00
IUUC-Mdo-063063	Monodelphis domestica	70.70	1.00e-151	529.00
IUUC-Mmu-064294	Mus musculus	96.06	0.00e+00	818.00
IUUC-Mac-065598	Musa acuminata	30.61	3.00e-33	136.00
IUUC-Mpu-066831	Mustela putorius furo	80.66	0.00e+00	696.00
IUUC-Mlu-067222	Myotis lucifugus	77.28	0.00e+00	689.00
IUUC-Nle-069581	Nomascus leucogenys	78.91	0.00e+00	711.00
IUUC-Opr-070644	Ochotona princeps	76.76	0.00e+00	667.00
IUUC-Ont-072605	Oreochromis niloticus	53.09	3.00e-111	395.00
IUUC-Oan-072973	Ornithorhynchus anatinus	68.30	5.00e-145	506.00
IUUC-Ocu-074615	Oryctolagus cuniculus	78.45	0.00e+00	707.00
IUUC-Oba-075283	Oryza barthii	29.79	5.00e-31	129.00
IUUC-Obr-076605	Oryza brachyantha	30.21	3.00e-32	133.00
IUUC-Ogl-077512	Oryza glaberrima	29.79	7.00e-31	128.00
IUUC-Ogu-078329	Oryza glumaepatula	29.79	5.00e-31	129.00
IUUC-Oin-079980	Oryza indica	29.79	9.00e-31	128.00
IUUC-Olo-080516	Oryza longistaminata	29.66	4.00e-31	129.00
IUUC-Ome-081415	Oryza meridionalis	29.79	6.00e-31	129.00
IUUC-Oni-082985	Oryza nivara	29.79	9.00e-31	128.00
IUUC-Opu-084159	Oryza punctata	29.97	8.00e-31	128.00
IUUC-Oru-085137	Oryza rufipogon	29.79	4.00e-31	129.00
IUUC-Osa-085614	Oryza sativa	29.79	4.00e-31	129.00
IUUC-Ola-087044	Oryzias latipes	46.47	2.00e-101	363.00
IUUC-Oga-088274	Otolemur garnettii	79.86	0.00e+00	712.00
IUUC-Oar-089826	Ovis aries	80.09	0.00e+00	720.00
IUUC-Ptr-091631	Pan troglodytes	78.91	0.00e+00	708.00
IUUC-Pan-092535	Papio anubis	78.44	0.00e+00	707.00
IUUC-Psi-093815	Pelodiscus sinensis	53.12	1.00e-118	420.00
IUUC-Pma-094474	Petromyzon marinus	48.66	3.00e-96	345.00
IUUC-Ppa-095414	Physcomitrella patens	28.53	6.00e-29	122.00
IUUC-Pfo-096559	Poecilia formosa	48.76	5.00e-99	355.00
IUUC-Pab-098528	Pongo abelii	78.67	0.00e+00	709.00
IUUC-Pop-100064	Populus trichocarpa	31.10	1.00e-37	151.00
IUUC-Pca-100803	Procavia capensis	75.88	0.00e+00	664.00
IUUC-Ppe-101966	Prunus persica	31.31	2.00e-37	150.00
IUUC-Pva-103213	Pteropus vampyrus	79.39	0.00e+00	664.00
IUUC-Sha-107466	Sarcophilus harrisii	70.22	9.00e-149	519.00
IUUC-Smo-108958	Selaginella moellendorffii	28.18	4.00e-27	115.00
IUUC-Sit-109968	Setaria italica	29.97	7.00e-30	125.00
IUUC-Sly-111495	Solanum lycopersicum	30.97	3.00e-36	146.00
IUUC-Stu-112182	Solanum tuberosum	28.79	7.00e-15	75.90
IUUC-Sar-113272	Sorex araneus	77.15	3.00e-160	557.00
IUUC-Sbi-114706	Sorghum bicolor	28.48	5.00e-28	119.00
IUUC-Ssc-115437	Sus scrofa	79.16	0.00e+00	699.00
IUUC-Tgu-116602	Taeniopygia guttata	56.65	6.00e-119	421.00
IUUC-Tru-118698	Takifugu rubripes	47.14	3.00e-92	332.00
IUUC-Tsy-119027	Tarsius syrichta	75.26	6.00e-178	616.00
IUUC-Tni-119787	Tetraodon nigroviridis	47.21	1.00e-98	353.00
IUUC-Tca-121447	Theobroma cacao	30.30	4.00e-37	149.00
IUUC-Tae-125839	Triticum aestivum	30.70	9.00e-33	135.00
IUUC-Tur-126724	Triticum urartu	30.70	8.00e-33	135.00
IUUC-Tbe-127680	Tupaia belangeri	78.55	1.00e-128	452.00
IUUC-Ttr-128201	Tursiops truncatus	69.56	2.00e-168	585.00
IUUC-Vpa-130451	Vicugna pacos	64.84	2.00e-99	355.00
IUUC-Vvi-131001	Vitis vinifera	30.70	9.00e-37	148.00
IUUC-Xtr-132266	Xenopus tropicalis	55.04	6.00e-125	441.00
IUUC-Xma-133034	Xiphophorus maculatus	53.09	2.00e-110	392.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence