iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.20e-06	29.2	43	109

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 3    vilvvggeeffahkivLaasSsvFyalflmele.esksklmveikdvqpevfrallkFlYtgkldene 69
           v l+vgg+   ++  +L+ +  +++a+f++  e  ++ ++ v i+ ++  +f ++l++l+ g+++++e
   Q: 43   VKLNVGGSLHYTTLRTLTGQDTMLKAMFSGRVEvLTDAGGWVLID-RSGRHFGTILNYLRDGSVPLPE 109
           99********************************9999******9.******************9986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSAEASGPAA AAAECLESPN PSGVEPGSPS YSLKPLTPNS KYVKLNVGGS LHYTTLRTLT 60
GQDTMLKAMF SGRVEVLTDA GGWVLIDRSG RHFGTILNYL RDGSVPLPES TRELGELLGE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAGCTTCCG GGTGGAGAGA GCGCGCGATG GGGCGGCTGG TGGACGTAGC AGAGTAGCGG 60
CGGCGAGTGG GCGTGTGCGC CGAGCGGTCG GGCGCCCGCG CAGGAGTCGC GGGGTCTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR003131--T1-type_BTB

PROSITE

PS50097--BTB

Pfam

PF02214--BTB_2

SMART

SM00225--BTB

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016604--C:nuclear body
GO:0019904--F:protein domain specific binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0030036--P:actin cytoskeleton organization
GO:0016477--P:cell migration
GO:0006281--P:DNA repair
GO:0006260--P:DNA replication
GO:0035024--P:negative regulation of Rho protein signal transduction
GO:0045740--P:positive regulation of DNA replication
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051291--P:protein heterooligomerization
GO:0051260--P:protein homooligomerization
GO:0006355--P:regulation of transcription, DNA-templated
GO:0043149--P:stress fiber assembly

KEGG

rno:293497

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001238	Ailuropoda melanoleuca	95.22	1.00e-154	538.00
IUUC-Aca-004311	Anolis carolinensis	80.46	2.00e-132	464.00
IUUC-Bta-012415	Bos taurus	93.63	4.00e-156	543.00
IUUC-Cja-019451	Callithrix jacchus	95.54	6.00e-156	543.00
IUUC-Cfa-020804	Canis familiaris	95.77	4.00e-156	543.00
IUUC-Cpo-022466	Cavia porcellus	96.55	1.00e-139	488.00
IUUC-Csa-023225	Chlorocebus sabaeus	96.42	1.00e-153	535.00
IUUC-Cho-024629	Choloepus hoffmanni	75.42	9.00e-100	356.00
IUUC-Dno-028944	Dasypus novemcinctus	96.18	8.00e-154	536.00
IUUC-Ete-032820	Echinops telfairi	79.68	3.00e-113	400.00
IUUC-Eca-034400	Equus caballus	96.25	2.00e-142	498.00
IUUC-Eeu-034457	Erinaceus europaeus	93.81	1.00e-136	479.00
IUUC-Fca-035698	Felis catus	96.74	4.00e-152	530.00
IUUC-Ggo-044675	Gorilla gorilla	96.43	4.00e-154	536.00
IUUC-Hsa-045986	Homo sapiens	96.09	5.00e-153	533.00
IUUC-Itr-048073	Ictidomys tridecemlineatus	95.54	4.00e-152	530.00
IUUC-Lch-049441	Latimeria chalumnae	76.70	1.00e-131	462.00
IUUC-Laf-053592	Loxodonta africana	95.22	2.00e-153	534.00
IUUC-Mcc-054864	Macaca mulatta	97.74	7.00e-131	459.00
IUUC-Mdo-062807	Monodelphis domestica	92.98	2.00e-133	468.00
IUUC-Mmu-064250	Mus musculus	99.05	9.00e-148	516.00
IUUC-Mpu-066138	Mustela putorius furo	97.18	8.00e-124	436.00
IUUC-Mlu-067108	Myotis lucifugus	95.04	2.00e-134	471.00
IUUC-Nle-069621	Nomascus leucogenys	96.09	5.00e-153	533.00
IUUC-Opr-070867	Ochotona princeps	93.67	6.00e-128	450.00
IUUC-Ocu-074347	Oryctolagus cuniculus	96.09	9.00e-154	535.00
IUUC-Oga-087959	Otolemur garnettii	96.18	4.00e-153	533.00
IUUC-Oar-089835	Ovis aries	94.27	2.00e-150	525.00
IUUC-Ptr-090744	Pan troglodytes	96.09	5.00e-153	533.00
IUUC-Pan-092607	Papio anubis	96.42	1.00e-153	535.00
IUUC-Psi-093501	Pelodiscus sinensis	81.99	6.00e-134	469.00
IUUC-Pab-098026	Pongo abelii	95.77	6.00e-153	533.00
IUUC-Pca-100340	Procavia capensis	94.82	4.00e-152	530.00
IUUC-Pva-102916	Pteropus vampyrus	94.86	6.00e-155	539.00
IUUC-Sha-107042	Sarcophilus harrisii	92.67	1.00e-133	468.00
IUUC-Sar-113695	Sorex araneus	94.07	7.00e-131	459.00
IUUC-Tsy-119307	Tarsius syrichta	78.14	1.00e-86	312.00
IUUC-Ttr-128588	Tursiops truncatus	97.57	5.00e-118	416.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence