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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-031598
Ensembl Protein ID FBpp0099495
UniProt Accession Q8I7C3; Q59E31; Q9VV91; LASP1_DROME
Genbank Protein ID CAC82378.1; AAF49426.3; AAN11739.2; AAO41484.1
Protein Name LIM and SH3 domain protein Lasp
Genbank Nucleotide ID AJ294538; AE014296; AE014296; BT003801
Gene Name Lasp; CG3849
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0063485 FBtr0100145 FBpp0099495
FBgn0063485 FBtr0075350 FBpp0075109
FBgn0063485 FBtr0306152 FBpp0297282
FBgn0063485 FBtr0306151 FBpp0297281
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDMentha
Post-translational Modifications (PTMs)
dbPAFdbPTMPhospho.ELMUniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 7.80e-15 54.6 598 655
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +++ +++ydyeaq+ de ++++Gdv++ +  e+ d gW+ g  e +gk G++P+n+ve++
   Q: 598  MRVYRAIYDYEAQDVDEVSFREGDVIFEV--ESIDSGWMTGRVERTGKTGMLPANYVEQA 655
           67889**********************99..9*************************985 PP
   
Organism Drosophila melanogaster
Protein Sequence
(Fasta)
MNKTCARCQK VVYPIEELKC LDKTWHKTCF KCTECGMTLN MKTYKGYNKM PYCEAHIPKA 60
KATAIADTPE LKRIAENTKI QSNVKYHADF EKAKGKFTQV ADDPETLRIK QNTKHISNVA 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-031598|UBD,SH3|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCTCGCAGTC TGCTGCGGTC ACTCTATTCG AACGGAACGG AATATTTATC GCGGATTGTC 60
GCGTTATTTC GTTTGTGTCG CGCCTCCATC AAACTCACCT TAAAAATTAA CACTCAAATC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031598|UBD,SH3|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0440--LIM domain
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain
KW-0862--Zinc
Interpro

IPR000900--Nebulin_repeat
IPR001452--SH3_domain
IPR001781--Znf_LIM
PROSITE

PS00478--LIM_DOMAIN_1
PS50023--LIM_DOMAIN_2
PS51216--NEBULIN
PS50002--SH3
Pfam

PF00412--LIM
PF00880--Nebulin
PF00018--SH3_1
PRINTS

PR00452--SH3DOMAIN
SMART

SM00132--LIM
SM00227--NEBU
SM00326--SH3
Gene Ontology

GO:0031672--C:A band
GO:0005829--C:cytosol
GO:0005925--C:focal adhesion
GO:0070864--C:sperm individualization complex
GO:0030018--C:Z disc
GO:0003779--F:actin binding
GO:0008270--F:zinc ion binding
GO:0071689--P:muscle thin filament assembly
GO:0007279--P:pole cell formation
GO:0045856--P:positive regulation of pole plasm oskar mRNA localization
GO:0014881--P:regulation of myofibril size
GO:0045214--P:sarcomere organization
GO:0007291--P:sperm individualization
GO:0007283--P:spermatogenesis
KEGG dme:Dmel_CG3849
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000663 Aegilops tauschii 34.00 2.00e-05 43.10
IUUC-Aml-001609 Ailuropoda melanoleuca 52.34 1.00e-35 142.00
IUUC-Apl-003494 Anas platyrhynchos 47.75 6.00e-26 110.00
IUUC-Aca-004462 Anolis carolinensis 52.34 4.00e-36 144.00
IUUC-Ame-011113 Astyanax mexicanus 50.78 4.00e-35 140.00
IUUC-Bta-012469 Bos taurus 52.34 6.00e-36 143.00
IUUC-Cel-018413 Caenorhabditis elegans 64.96 6.00e-52 196.00
IUUC-Cja-019147 Callithrix jacchus 61.97 1.00e-20 94.70
IUUC-Cfa-020384 Canis familiaris 52.34 3.00e-36 144.00
IUUC-Cpo-022244 Cavia porcellus 41.38 1.00e-26 112.00
IUUC-Csa-023039 Chlorocebus sabaeus 52.34 5.00e-36 143.00
IUUC-Cho-024491 Choloepus hoffmanni 67.80 8.00e-20 94.70
IUUC-Cin-025236 Ciona intestinalis 53.28 2.00e-35 141.00
IUUC-Csv-026002 Ciona savignyi 57.84 6.00e-33 133.00
IUUC-Dre-028335 Danio rerio 52.34 5.00e-36 143.00
IUUC-Dno-029377 Dasypus novemcinctus 48.91 2.00e-19 88.60
IUUC-Dor-031101 Dipodomys ordii 55.79 2.00e-22 98.60
IUUC-Ete-032651 Echinops telfairi 66.10 2.00e-13 73.60
IUUC-Eca-033966 Equus caballus 50.00 5.00e-26 110.00
IUUC-Eeu-034613 Erinaceus europaeus 63.38 5.00e-21 95.90
IUUC-Fca-035699 Felis catus 52.34 5.00e-36 143.00
IUUC-Fal-037225 Ficedula albicollis 62.50 2.00e-21 97.10
IUUC-Gmo-039493 Gadus morhua 52.88 5.00e-27 113.00
IUUC-Gga-040316 Gallus gallus 54.69 5.00e-36 143.00
IUUC-Gac-042632 Gasterosteus aculeatus 58.33 3.00e-44 170.00
IUUC-Ggo-044835 Gorilla gorilla 52.34 1.00e-35 142.00
IUUC-Hsa-046825 Homo sapiens 52.34 5.00e-36 143.00
IUUC-Hvu-047551 Hordeum vulgare 34.00 2.00e-05 43.10
IUUC-Itr-048498 Ictidomys tridecemlineatus 50.00 6.00e-26 109.00
IUUC-Lch-049942 Latimeria chalumnae 71.43 2.00e-21 97.40
IUUC-Lpe-050758 Leersia perrieri 39.39 1.00e-03 37.40
IUUC-Loc-052082 Lepisosteus oculatus 53.12 1.00e-36 145.00
IUUC-Laf-053578 Loxodonta africana 52.34 3.00e-36 144.00
IUUC-Mcc-055650 Macaca mulatta 52.34 5.00e-36 143.00
IUUC-Meu-056479 Macropus eugenii 40.14 1.00e-26 112.00
IUUC-Mga-059763 Meleagris gallopavo 52.29 5.00e-26 110.00
IUUC-Mmr-061164 Microcebus murinus 52.34 5.00e-36 143.00
IUUC-Mdo-061979 Monodelphis domestica 43.27 5.00e-37 146.00
IUUC-Mmu-063302 Mus musculus 52.34 2.00e-36 144.00
IUUC-Mac-065516 Musa acuminata 36.36 1.00e-03 35.00
IUUC-Mpu-066114 Mustela putorius furo 52.34 3.00e-36 144.00
IUUC-Mlu-068217 Myotis lucifugus 44.77 9.00e-37 145.00
IUUC-Nle-069636 Nomascus leucogenys 71.70 6.00e-19 86.70
IUUC-Opr-070892 Ochotona princeps 56.25 2.00e-41 161.00
IUUC-Ont-072280 Oreochromis niloticus 57.72 6.00e-40 156.00
IUUC-Oan-072876 Ornithorhynchus anatinus 63.89 2.00e-21 97.80
IUUC-Ocu-073804 Oryctolagus cuniculus 56.25 2.00e-41 161.00
IUUC-Ogu-078055 Oryza glumaepatula 36.36 3.00e-03 35.80
IUUC-Olo-081092 Oryza longistaminata 36.36 5.00e-03 35.80
IUUC-Oni-082309 Oryza nivara 36.36 2.00e-03 36.20
IUUC-Oru-085213 Oryza rufipogon 36.36 2.00e-03 36.20
IUUC-Ola-086514 Oryzias latipes 56.59 6.00e-41 160.00
IUUC-Oga-088707 Otolemur garnettii 52.34 5.00e-36 143.00
IUUC-Oar-089771 Ovis aries 52.34 2.00e-36 144.00
IUUC-Ptr-091237 Pan troglodytes 52.34 5.00e-36 143.00
IUUC-Pan-092656 Papio anubis 52.34 5.00e-36 143.00
IUUC-Psi-093861 Pelodiscus sinensis 62.50 2.00e-21 97.10
IUUC-Pma-094377 Petromyzon marinus 49.19 3.00e-32 130.00
IUUC-Pfo-097079 Poecilia formosa 49.22 4.00e-35 140.00
IUUC-Pab-097833 Pongo abelii 52.34 6.00e-36 143.00
IUUC-Pca-100691 Procavia capensis 52.34 5.00e-36 143.00
IUUC-Pva-102270 Pteropus vampyrus 52.34 6.00e-36 143.00
IUUC-Rno-105362 Rattus norvegicus 52.34 2.00e-36 144.00
IUUC-Sha-107134 Sarcophilus harrisii 40.25 3.00e-27 114.00
IUUC-Smo-108841 Selaginella moellendorffii 42.42 4.00e-04 38.10
IUUC-Sar-113072 Sorex araneus 63.38 4.00e-21 96.30
IUUC-Ssc-115305 Sus scrofa 71.43 7.00e-21 95.50
IUUC-Tru-118693 Takifugu rubripes 54.62 7.00e-43 166.00
IUUC-Tsy-119452 Tarsius syrichta 61.97 1.00e-20 94.70
IUUC-Tni-120393 Tetraodon nigroviridis 53.49 2.00e-40 157.00
IUUC-Tae-125777 Triticum aestivum 34.00 2.00e-05 42.70
IUUC-Tur-126326 Triticum urartu 34.00 2.00e-05 43.10
IUUC-Tbe-127585 Tupaia belangeri 69.64 1.00e-20 94.70
IUUC-Ttr-128639 Tursiops truncatus 48.44 3.00e-29 120.00
IUUC-Vpa-130371 Vicugna pacos 63.38 4.00e-21 96.30
IUUC-Xtr-131827 Xenopus tropicalis 53.91 9.00e-40 155.00
Created Date 25-Jun-2017

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