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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-047036
Ensembl Protein ID ENSP00000384302.3
UniProt Accession Q15061; Q15395; Q92577; WDR43_HUMAN
Genbank Protein ID BAA05499.1; BAA13441.1
Protein Name WD repeat-containing protein 43; U3 small nucleolar RNA-associated protein 5 homolog
Genbank Nucleotide ID D26488; D87716
Gene Name WDR43; KIAA0007; UTP5
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000163811.11 ENST00000407426.7 ENSP00000384302.3
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
GWASdbGWAS CentralOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDABioGRID
mUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.40e-16 60.3 124 160
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH ++v+c+++ +d + l s+sdD+ i  W++ t+++
   Q: 124  GHDNRVNCIQWhQDsGCLYSCSDDKHIVEWNVQTCKV 160
           8***********7789***********9999988776 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MAAGGGGSCD PLAPAGVPCA FSPHSQAYFA LASTDGHLRV WETANNRLHQ EYVPSAHLSG 60
TCTCLAWAPA RLQAKESPQR KKRKSEAVGM SNQTDLLALG TAVGSILLYS TVKGELHSKL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-047036|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCGCCGGTGC GCCTGCGCAC GGACGAACAC GTGGCTGCAG CGGGGCCAGA GCAGCAATGG 60
CGGCGGGCGG CGGCGGTAGC TGCGACCCCC TGGCCCCTGC TGGGGTCCCT TGCGCCTTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-047036|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0832--Ubl conjugation
KW-0853--WD repeat
Interpro

IPR023302--Pept_S9A_N
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF04003--Utp12
PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0001650--C:fibrillar center
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0003723--F:RNA binding
GO:0006364--P:rRNA processing
KEGG hsa:23160
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001865 Ailuropoda melanoleuca 93.57 0.00e+00 1113.00
IUUC-Atr-002533 Amborella trichopoda 20.42 4.00e-24 106.00
IUUC-Apl-003242 Anas platyrhynchos 73.81 0.00e+00 798.00
IUUC-Aca-004607 Anolis carolinensis 71.93 0.00e+00 868.00
IUUC-Aly-006074 Arabidopsis lyrata 25.80 2.00e-16 80.90
IUUC-Ath-007222 Arabidopsis thaliana 25.80 5.00e-16 79.70
IUUC-Ame-011014 Astyanax mexicanus 54.11 5.00e-172 597.00
IUUC-Bta-012605 Bos taurus 92.50 0.00e+00 1117.00
IUUC-Bdi-014072 Brachypodium distachyon 20.80 2.00e-20 94.40
IUUC-Bol-016255 Brassica oleracea 23.04 1.00e-23 105.00
IUUC-Bra-016850 Brassica rapa 27.27 8.00e-24 105.00
IUUC-Cja-019620 Callithrix jacchus 98.50 0.00e+00 1191.00
IUUC-Cfa-020520 Canis familiaris 93.00 0.00e+00 1123.00
IUUC-Cpo-022456 Cavia porcellus 85.74 0.00e+00 1097.00
IUUC-Cho-024726 Choloepus hoffmanni 88.32 0.00e+00 1087.00
IUUC-Cin-025761 Ciona intestinalis 35.67 2.00e-96 347.00
IUUC-Dre-028051 Danio rerio 53.00 4.00e-180 624.00
IUUC-Dno-030031 Dasypus novemcinctus 90.55 0.00e+00 1129.00
IUUC-Dme-031653 Drosophila melanogaster 26.53 3.00e-47 183.00
IUUC-Ete-032863 Echinops telfairi 81.34 5.00e-92 332.00
IUUC-Eca-033243 Equus caballus 93.20 0.00e+00 957.00
IUUC-Eeu-034970 Erinaceus europaeus 88.13 0.00e+00 796.00
IUUC-Fca-036009 Felis catus 92.89 0.00e+00 1107.00
IUUC-Fal-037264 Ficedula albicollis 72.05 0.00e+00 775.00
IUUC-Gmo-039124 Gadus morhua 56.01 2.00e-179 622.00
IUUC-Gga-040862 Gallus gallus 72.53 0.00e+00 855.00
IUUC-Gac-041468 Gasterosteus aculeatus 55.84 0.00e+00 645.00
IUUC-Gma-042795 Glycine max 21.05 3.00e-14 73.60
IUUC-Ggo-044432 Gorilla gorilla 99.67 0.00e+00 1206.00
IUUC-Itr-048644 Ictidomys tridecemlineatus 93.82 0.00e+00 1128.00
IUUC-Lch-049553 Latimeria chalumnae 62.65 0.00e+00 763.00
IUUC-Laf-053462 Loxodonta africana 91.33 0.00e+00 1136.00
IUUC-Mcc-055239 Macaca mulatta 98.83 0.00e+00 1191.00
IUUC-Mtr-057977 Medicago truncatula 22.61 8.00e-20 92.40
IUUC-Mga-060079 Meleagris gallopavo 73.62 0.00e+00 783.00
IUUC-Mmr-061472 Microcebus murinus 94.67 0.00e+00 1136.00
IUUC-Mdo-061972 Monodelphis domestica 78.51 0.00e+00 1029.00
IUUC-Mmu-063354 Mus musculus 87.98 0.00e+00 1056.00
IUUC-Mac-065064 Musa acuminata 23.64 5.00e-17 82.40
IUUC-Mpu-066877 Mustela putorius furo 92.17 0.00e+00 1117.00
IUUC-Mlu-067476 Myotis lucifugus 89.98 0.00e+00 1083.00
IUUC-Nle-069119 Nomascus leucogenys 99.33 0.00e+00 1200.00
IUUC-Ont-072093 Oreochromis niloticus 55.46 0.00e+00 683.00
IUUC-Oan-072944 Ornithorhynchus anatinus 73.15 0.00e+00 861.00
IUUC-Ocu-074472 Oryctolagus cuniculus 94.32 0.00e+00 1100.00
IUUC-Oba-075009 Oryza barthii 21.65 2.00e-17 84.70
IUUC-Ogl-077189 Oryza glaberrima 20.89 4.00e-17 83.20
IUUC-Oin-079064 Oryza indica 21.77 4.00e-17 83.60
IUUC-Opu-083604 Oryza punctata 21.73 4.00e-15 76.60
IUUC-Oru-084620 Oryza rufipogon 21.77 4.00e-17 83.60
IUUC-Osa-085345 Oryza sativa 21.95 2.00e-17 84.30
IUUC-Ola-086626 Oryzias latipes 54.08 0.00e+00 665.00
IUUC-Oga-087911 Otolemur garnettii 94.09 0.00e+00 1122.00
IUUC-Ptr-091603 Pan troglodytes 99.70 0.00e+00 1233.00
IUUC-Pan-092569 Papio anubis 98.83 0.00e+00 1191.00
IUUC-Pma-094287 Petromyzon marinus 53.45 0.00e+00 644.00
IUUC-Ppa-095327 Physcomitrella patens 27.58 1.00e-27 118.00
IUUC-Pfo-097292 Poecilia formosa 54.84 0.00e+00 639.00
IUUC-Pab-097878 Pongo abelii 99.83 0.00e+00 1186.00
IUUC-Pop-099418 Populus trichocarpa 22.50 1.00e-18 88.60
IUUC-Pca-100941 Procavia capensis 84.97 0.00e+00 993.00
IUUC-Ppe-101779 Prunus persica 20.36 2.00e-20 94.00
IUUC-Pva-102493 Pteropus vampyrus 85.33 0.00e+00 1019.00
IUUC-Rno-105084 Rattus norvegicus 89.15 0.00e+00 1064.00
IUUC-Sha-107486 Sarcophilus harrisii 81.36 0.00e+00 1003.00
IUUC-Smo-108825 Selaginella moellendorffii 22.68 5.00e-21 96.30
IUUC-Sit-110825 Setaria italica 22.59 1.00e-21 98.20
IUUC-Sly-111365 Solanum lycopersicum 23.36 2.00e-22 101.00
IUUC-Stu-112812 Solanum tuberosum 23.47 2.00e-20 94.40
IUUC-Sar-113326 Sorex araneus 93.75 2.00e-140 493.00
IUUC-Sbi-114426 Sorghum bicolor 22.08 3.00e-24 106.00
IUUC-Tgu-116726 Taeniopygia guttata 69.66 0.00e+00 836.00
IUUC-Tru-117848 Takifugu rubripes 54.46 0.00e+00 645.00
IUUC-Tsy-119091 Tarsius syrichta 66.67 4.00e-135 474.00
IUUC-Tni-120591 Tetraodon nigroviridis 54.98 0.00e+00 647.00
IUUC-Tca-121576 Theobroma cacao 25.49 5.00e-17 83.20
IUUC-Tae-125105 Triticum aestivum 22.62 2.00e-22 100.00
IUUC-Tbe-127832 Tupaia belangeri 92.94 0.00e+00 974.00
IUUC-Ttr-128812 Tursiops truncatus 88.54 0.00e+00 994.00
IUUC-Xma-133557 Xiphophorus maculatus 54.84 0.00e+00 642.00
Created Date 25-Jun-2017

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