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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-046408
UUCD1 version UUC-HoS-00965
Ensembl Protein ID ENSP00000378857.3
UniProt Accession A0A087X295; A0A087X295_HUMAN
Genbank Protein ID ENSP00000378857
Protein Name WD repeat-containing protein 6
Genbank Nucleotide ID AC137630
Gene Name WDR6
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000178252.17 ENST00000395474.7 ENSP00000378857.3
ENSG00000178252.17 ENST00000438660.5 ENSP00000387692.1
ENSG00000178252.17 ENST00000415265.6 ENSP00000412195.2
ENSG00000178252.17 ENST00000452875.5 ENSP00000414157.1
ENSG00000178252.17 ENST00000420783.7 ENSP00000395993.3
ENSG00000178252.17 ENST00000419837.1 ENSP00000390740.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
iRefIndexHINTInWeb_IM
Disease-associated Variation
ClinVarOMIM
Post-translational Modifications (PTMs)
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.20e-19 71.2 945 979
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 8    cla.f....sd....tllvsGsdDgtikvWDlrtg 33
            ++ f    ++     ll+s++ Dg++  WDl+t 
   Q: 945  KVHsFtheaPNqrrrLLLCSAATDGSLAFWDLTTM 979
           5544666663322212489999**********985 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MGSAARWEGS FSREFSSLLS RGCLSTSRID MDALEDYVWP RATSELILLP VTGLECVGDR 60
LLAGEGPDVL VYSLDFGGHL RMIKRVQNLL GHYLIHGFRV RPEPNGDLDL EAMVAVFGSK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046408|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TTTATTGTGT ACTGACTCCA TCTGCCCCGT CAAATAAAAA ACCACAAGGT TCGAGCCGCC 60
GGGCCCGACA AACTCCGGGT CGGCGAAACA GAGTCCGCGA TAGGTGCAGC GGGCTGGCAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046408|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005829--C:cytosol
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000976 Aegilops tauschii 20.71 2.00e-20 95.50
IUUC-Aml-001786 Ailuropoda melanoleuca 93.51 0.00e+00 2067.00
IUUC-Atr-003053 Amborella trichopoda 22.41 7.00e-29 123.00
IUUC-Apl-003178 Anas platyrhynchos 47.43 3.00e-139 488.00
IUUC-Aca-004886 Anolis carolinensis 44.72 0.00e+00 853.00
IUUC-Aly-005509 Arabidopsis lyrata 24.44 1.00e-39 159.00
IUUC-Ath-007109 Arabidopsis thaliana 23.85 2.00e-37 152.00
IUUC-Ago-007817 Ashbya gossypii 22.67 1.00e-42 168.00
IUUC-Acl-008020 Aspergillus clavatus 22.09 5.00e-26 114.00
IUUC-Afl-008608 Aspergillus flavus 21.65 6.00e-17 83.20
IUUC-Afu-009035 Aspergillus fumigatus 22.18 7.00e-28 119.00
IUUC-Ani-009359 Aspergillus nidulans 24.00 2.00e-24 108.00
IUUC-Ang-009692 Aspergillus niger 26.47 6.00e-11 63.90
IUUC-Aor-010056 Aspergillus oryzae 22.19 4.00e-28 120.00
IUUC-Ate-010299 Aspergillus terreus 22.33 1.00e-28 122.00
IUUC-Ame-011051 Astyanax mexicanus 33.53 3.00e-147 516.00
IUUC-Bgr-012077 Blumeria graminis 21.09 1.00e-11 65.90
IUUC-Bta-012793 Bos taurus 89.71 0.00e+00 1965.00
IUUC-Bci-013679 Botrytis cinerea 20.87 2.00e-09 58.90
IUUC-Bdi-014401 Brachypodium distachyon 23.10 8.00e-34 139.00
IUUC-Bol-015628 Brassica oleracea 24.51 9.00e-30 126.00
IUUC-Bra-017446 Brassica rapa 24.77 6.00e-33 136.00
IUUC-Cja-018910 Callithrix jacchus 95.93 0.00e+00 2119.00
IUUC-Cfa-021260 Canis familiaris 93.40 0.00e+00 2073.00
IUUC-Cpo-022205 Cavia porcellus 87.11 0.00e+00 1979.00
IUUC-Csa-023510 Chlorocebus sabaeus 97.39 0.00e+00 2146.00
IUUC-Cgl-026380 Colletotrichum gloeosporioides 26.22 9.00e-10 59.30
IUUC-Dre-028004 Danio rerio 33.91 2.00e-155 543.00
IUUC-Dno-029804 Dasypus novemcinctus 86.21 0.00e+00 1891.00
IUUC-Dor-030512 Dipodomys ordii 82.71 0.00e+00 1482.00
IUUC-Dme-032047 Drosophila melanogaster 22.59 2.00e-28 121.00
IUUC-Ete-033076 Echinops telfairi 83.54 0.00e+00 702.00
IUUC-Eca-033727 Equus caballus 93.38 0.00e+00 1655.00
IUUC-Eeu-035210 Erinaceus europaeus 84.66 0.00e+00 1911.00
IUUC-Fca-035433 Felis catus 92.96 0.00e+00 2068.00
IUUC-Fal-036807 Ficedula albicollis 45.91 6.00e-160 557.00
IUUC-Fox-037749 Fusarium oxysporum 22.57 5.00e-17 84.00
IUUC-Fso-038164 Fusarium solani 24.94 1.00e-10 62.80
IUUC-Gmo-039180 Gadus morhua 35.84 4.00e-141 495.00
IUUC-Gga-040482 Gallus gallus 43.52 1.00e-173 604.00
IUUC-Gac-042066 Gasterosteus aculeatus 36.16 7.00e-153 535.00
IUUC-Gma-042704 Glycine max 22.58 4.00e-29 124.00
IUUC-Ggo-044942 Gorilla gorilla 99.13 0.00e+00 2149.00
IUUC-Hvu-047448 Hordeum vulgare 21.38 3.00e-24 108.00
IUUC-Itr-048756 Ictidomys tridecemlineatus 91.88 0.00e+00 2069.00
IUUC-Kpa-049257 Komagataella pastoris 21.55 2.00e-38 155.00
IUUC-Lch-050170 Latimeria chalumnae 41.77 0.00e+00 858.00
IUUC-Lpe-051575 Leersia perrieri 21.12 1.00e-30 129.00
IUUC-Loc-052341 Lepisosteus oculatus 34.91 5.00e-134 472.00
IUUC-Lma-053318 Leptosphaeria maculans 23.92 3.00e-12 67.80
IUUC-Laf-054299 Loxodonta africana 87.54 0.00e+00 1919.00
IUUC-Mcc-055438 Macaca mulatta 97.65 0.00e+00 2123.00
IUUC-Meu-056206 Macropus eugenii 47.35 0.00e+00 642.00
IUUC-Mor-056928 Magnaporthe oryzae 24.29 2.00e-15 79.00
IUUC-Mtr-058455 Medicago truncatula 24.44 1.00e-30 129.00
IUUC-Mga-059962 Meleagris gallopavo 45.92 1.00e-148 520.00
IUUC-Mvi-060438 Microbotryum violaceum 26.91 7.00e-16 80.10
IUUC-Mmr-061353 Microcebus murinus 92.18 0.00e+00 2096.00
IUUC-Mdo-062061 Monodelphis domestica 50.43 0.00e+00 901.00
IUUC-Mmu-064386 Mus musculus 86.49 0.00e+00 1961.00
IUUC-Mac-065653 Musa acuminata 22.94 2.00e-42 168.00
IUUC-Mpu-066420 Mustela putorius furo 92.51 0.00e+00 2078.00
IUUC-Mlu-068104 Myotis lucifugus 87.60 0.00e+00 1960.00
IUUC-Nfi-068301 Neosartorya fischeri 21.84 5.00e-27 117.00
IUUC-Ncr-068718 Neurospora crassa 22.45 1.00e-12 69.70
IUUC-Nle-069836 Nomascus leucogenys 87.39 0.00e+00 1599.00
IUUC-Ont-071605 Oreochromis niloticus 35.42 1.00e-160 561.00
IUUC-Oan-073645 Ornithorhynchus anatinus 48.15 0.00e+00 981.00
IUUC-Ocu-074708 Oryctolagus cuniculus 88.32 0.00e+00 1941.00
IUUC-Oba-075290 Oryza barthii 26.06 9.00e-21 96.70
IUUC-Obr-076647 Oryza brachyantha 22.07 4.00e-29 124.00
IUUC-Ogl-077628 Oryza glaberrima 27.43 1.00e-26 115.00
IUUC-Ogu-078209 Oryza glumaepatula 21.82 1.00e-21 99.40
IUUC-Oin-079342 Oryza indica 27.43 1.00e-27 119.00
IUUC-Olo-080334 Oryza longistaminata 26.83 3.00e-21 99.00
IUUC-Ome-081776 Oryza meridionalis 24.92 1.00e-20 96.30
IUUC-Oni-082311 Oryza nivara 27.43 2.00e-27 119.00
IUUC-Opu-083195 Oryza punctata 21.45 2.00e-29 125.00
IUUC-Oru-085006 Oryza rufipogon 25.76 4.00e-20 94.40
IUUC-Osa-085317 Oryza sativa 27.14 4.00e-26 114.00
IUUC-Ola-087145 Oryzias latipes 35.44 2.00e-142 500.00
IUUC-Olu-087785 Ostreococcus lucimarinus 25.00 1.00e-10 62.40
IUUC-Oga-088206 Otolemur garnettii 93.04 0.00e+00 2119.00
IUUC-Oar-089802 Ovis aries 89.05 0.00e+00 1939.00
IUUC-Ptr-091528 Pan troglodytes 90.79 0.00e+00 1947.00
IUUC-Pan-092782 Papio anubis 97.74 0.00e+00 2132.00
IUUC-Psi-093102 Pelodiscus sinensis 48.52 4.00e-134 471.00
IUUC-Ppa-095436 Physcomitrella patens 22.87 1.00e-34 142.00
IUUC-Pfo-097423 Poecilia formosa 34.31 1.00e-145 511.00
IUUC-Pab-097763 Pongo abelii 99.20 0.00e+00 2127.00
IUUC-Pop-099090 Populus trichocarpa 26.84 8.00e-24 106.00
IUUC-Pca-100173 Procavia capensis 84.88 0.00e+00 1900.00
IUUC-Ppe-101580 Prunus persica 24.58 6.00e-33 137.00
IUUC-Pva-102715 Pteropus vampyrus 91.64 0.00e+00 2023.00
IUUC-Pgr-103424 Puccinia graminis 24.63 4.00e-13 70.50
IUUC-Pte-104316 Pyrenophora teres 22.70 2.00e-10 62.00
IUUC-Pyt-104676 Pyrenophora triticirepentis 22.53 2.00e-09 58.90
IUUC-Rno-105122 Rattus norvegicus 88.44 0.00e+00 2015.00
IUUC-Sce-106465 Saccharomyces cerevisiae 20.53 3.00e-26 114.00
IUUC-Sha-107208 Sarcophilus harrisii 48.55 0.00e+00 1008.00
IUUC-Sja-107771 Schizosaccharomyces japonicus 22.63 1.00e-20 95.90
IUUC-Spo-108272 Schizosaccharomyces pombe 21.28 1.00e-36 148.00
IUUC-Ssl-108576 Sclerotinia sclerotiorum 21.93 8.00e-06 46.60
IUUC-Smo-108961 Selaginella moellendorffii 23.80 1.00e-43 172.00
IUUC-Sit-109932 Setaria italica 21.93 3.00e-34 141.00
IUUC-Sly-111685 Solanum lycopersicum 24.84 2.00e-34 142.00
IUUC-Sar-112998 Sorex araneus 87.34 0.00e+00 1986.00
IUUC-Sbi-114074 Sorghum bicolor 21.67 8.00e-35 143.00
IUUC-Ssc-115619 Sus scrofa 92.28 0.00e+00 992.00
IUUC-Tgu-117485 Taeniopygia guttata 46.08 9.00e-154 536.00
IUUC-Tru-118104 Takifugu rubripes 35.95 3.00e-159 556.00
IUUC-Tni-119995 Tetraodon nigroviridis 36.66 2.00e-155 543.00
IUUC-Tca-121790 Theobroma cacao 23.49 2.00e-32 135.00
IUUC-Tre-122080 Trichoderma reesei 21.90 2.00e-14 75.10
IUUC-Tvi-122306 Trichoderma virens 22.07 1.00e-15 79.30
IUUC-Tae-125371 Triticum aestivum 22.22 3.00e-34 141.00
IUUC-Tur-126787 Triticum urartu 22.19 2.00e-31 131.00
IUUC-Tbe-128082 Tupaia belangeri 92.36 9.00e-157 547.00
IUUC-Ttr-128387 Tursiops truncatus 92.48 0.00e+00 1013.00
IUUC-Vda-129804 Verticillium dahliae 21.86 3.00e-14 74.70
IUUC-Vpa-130257 Vicugna pacos 91.75 2.00e-166 579.00
IUUC-Vvi-131701 Vitis vinifera 29.45 2.00e-27 119.00
IUUC-Xtr-132622 Xenopus tropicalis 41.94 0.00e+00 859.00
IUUC-Xma-134014 Xiphophorus maculatus 35.39 6.00e-153 535.00
IUUC-Yli-134589 Yarrowia lipolytica 21.89 8.00e-23 102.00
IUUC-Zma-135732 Zea mays 21.23 1.00e-36 149.00
Created Date 25-Jun-2017

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