iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	PINA	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.60e-07	31.8	1077	1118

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C +C++df  ++ ++vlpC H fha+C+ kw       + + +CP+Cr
   Q: 1077 CVVCMCDFelRQLLRVLPCSHEFHAKCVDKW------LRSNRTCPICR 1118
           ********6633399****************......**********8 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MLNSNATGGN NHGGSSRRPF TRNSSSVRSQ RGGGGGLGGR MVYSPHTHPH VQQQQQQQQQ 60
QQQQGQQRSS NNGNNNLWLG NSPWCNVNLN GGNSGNNNNN GGNNNNNNGG NISSNNNSNN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGTCTCGCCG CGGCCACACT CTTTGTCAGG TCGAACCCAA GGTAAACTCC CATAAAGCGT 60
AAAAATTTAA GACCTTTCCT GCCTAGCAAT TTGGACTCGA TAGGAAGTAA TAATGTATAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING

Gene Ontology

GO:0005634--C:nucleus
GO:0061630--F:ubiquitin protein ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0048149--P:behavioral response to ethanol
GO:0007611--P:learning or memory
GO:0007616--P:long-term memory
GO:0008355--P:olfactory learning
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination
GO:2001020--P:regulation of response to DNA damage stimulus

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000392	Aegilops tauschii	44.00	5.00e-15	73.60
IUUC-Aml-002180	Ailuropoda melanoleuca	64.96	1.00e-42	166.00
IUUC-Atr-002500	Amborella trichopoda	43.66	3.00e-15	75.90
IUUC-Apl-003246	Anas platyrhynchos	73.53	2.00e-43	169.00
IUUC-Aca-004353	Anolis carolinensis	65.81	7.00e-43	167.00
IUUC-Aly-005825	Arabidopsis lyrata	37.50	5.00e-13	67.40
IUUC-Ath-007389	Arabidopsis thaliana	38.89	6.00e-14	70.90
IUUC-Afu-009114	Aspergillus fumigatus	33.98	2.00e-12	67.00
IUUC-Ame-011569	Astyanax mexicanus	69.44	2.00e-42	166.00
IUUC-Bta-012401	Bos taurus	75.26	1.00e-43	169.00
IUUC-Bdi-014934	Brachypodium distachyon	32.65	7.00e-15	74.70
IUUC-Bol-015392	Brassica oleracea	37.27	5.00e-15	74.70
IUUC-Bra-016690	Brassica rapa	36.29	4.00e-16	77.80
IUUC-Cja-018848	Callithrix jacchus	73.74	2.00e-42	166.00
IUUC-Cfa-020959	Canis familiaris	64.66	1.00e-42	166.00
IUUC-Cpo-022130	Cavia porcellus	64.00	4.00e-45	174.00
IUUC-Cre-022984	Chlamydomonas reinhardtii	36.00	1.00e-13	72.00
IUUC-Csa-024265	Chlorocebus sabaeus	64.66	1.00e-42	166.00
IUUC-Cho-024540	Choloepus hoffmanni	77.27	2.00e-40	159.00
IUUC-Cin-025552	Ciona intestinalis	59.66	2.00e-37	147.00
IUUC-Dre-028201	Danio rerio	76.29	5.00e-44	171.00
IUUC-Dno-030071	Dasypus novemcinctus	63.79	4.00e-42	164.00
IUUC-Dor-030199	Dipodomys ordii	65.25	2.00e-43	169.00
IUUC-Dse-031302	Dothistroma septosporum	42.86	3.00e-11	62.80
IUUC-Ete-032580	Echinops telfairi	67.01	9.00e-37	147.00
IUUC-Eca-034105	Equus caballus	64.96	1.00e-42	166.00
IUUC-Eeu-035181	Erinaceus europaeus	44.33	2.00e-17	83.20
IUUC-Fca-036360	Felis catus	64.66	8.00e-43	167.00
IUUC-Fal-037494	Ficedula albicollis	66.67	5.00e-43	167.00
IUUC-Gmo-038591	Gadus morhua	66.94	6.00e-47	180.00
IUUC-Gga-040685	Gallus gallus	67.52	7.00e-45	173.00
IUUC-Gac-042255	Gasterosteus aculeatus	65.32	3.00e-45	175.00
IUUC-Gma-043292	Glycine max	46.48	4.00e-16	78.20
IUUC-Ggo-044571	Gorilla gorilla	75.26	9.00e-44	170.00
IUUC-Hsa-046118	Homo sapiens	75.26	9.00e-44	170.00
IUUC-Hvu-047392	Hordeum vulgare	37.74	1.00e-14	73.20
IUUC-Itr-048694	Ictidomys tridecemlineatus	64.66	5.00e-43	167.00
IUUC-Lch-050227	Latimeria chalumnae	66.96	1.00e-43	169.00
IUUC-Lpe-051339	Leersia perrieri	45.21	3.00e-15	75.50
IUUC-Loc-052875	Lepisosteus oculatus	66.67	5.00e-44	171.00
IUUC-Lma-052952	Leptosphaeria maculans	30.19	2.00e-11	63.20
IUUC-Laf-053419	Loxodonta africana	64.29	2.00e-45	175.00
IUUC-Mcc-055576	Macaca mulatta	75.26	9.00e-44	170.00
IUUC-Meu-056404	Macropus eugenii	66.67	1.00e-46	179.00
IUUC-Mor-057098	Magnaporthe oryzae	41.27	2.00e-12	66.20
IUUC-Mtr-058167	Medicago truncatula	48.57	2.00e-15	75.90
IUUC-Mla-059067	Melampsora laricipopulina	36.51	3.00e-09	56.60
IUUC-Mga-059597	Meleagris gallopavo	66.67	2.00e-43	168.00
IUUC-Mvi-060267	Microbotryum violaceum	28.00	1.00e-11	65.10
IUUC-Mmr-061247	Microcebus murinus	75.26	1.00e-43	170.00
IUUC-Mdo-062309	Monodelphis domestica	66.67	1.00e-46	179.00
IUUC-Mmu-063712	Mus musculus	65.81	9.00e-44	170.00
IUUC-Mac-064684	Musa acuminata	44.93	2.00e-15	75.90
IUUC-Mpu-066571	Mustela putorius furo	75.26	1.00e-43	170.00
IUUC-Mlu-067948	Myotis lucifugus	75.26	6.00e-44	171.00
IUUC-Nle-069466	Nomascus leucogenys	75.26	8.00e-44	170.00
IUUC-Opr-071167	Ochotona princeps	62.20	8.00e-43	166.00
IUUC-Ont-072424	Oreochromis niloticus	65.32	5.00e-46	177.00
IUUC-Oan-073236	Ornithorhynchus anatinus	74.47	2.00e-40	159.00
IUUC-Ocu-073866	Oryctolagus cuniculus	66.67	4.00e-44	171.00
IUUC-Oba-075403	Oryza barthii	38.98	5.00e-16	78.20
IUUC-Obr-076503	Oryza brachyantha	38.98	1.00e-15	76.60
IUUC-Ogl-077574	Oryza glaberrima	38.98	5.00e-16	78.20
IUUC-Ogu-077986	Oryza glumaepatula	38.98	5.00e-16	78.20
IUUC-Oin-079091	Oryza indica	38.98	6.00e-16	78.20
IUUC-Olo-080454	Oryza longistaminata	39.47	1.00e-14	73.60
IUUC-Ome-081627	Oryza meridionalis	38.98	6.00e-16	78.20
IUUC-Oni-082260	Oryza nivara	38.98	5.00e-16	78.20
IUUC-Opu-083578	Oryza punctata	38.98	7.00e-16	77.80
IUUC-Oru-084794	Oryza rufipogon	38.98	5.00e-16	78.20
IUUC-Osa-085348	Oryza sativa	38.98	5.00e-16	78.20
IUUC-Ola-086904	Oryzias latipes	66.13	7.00e-46	177.00
IUUC-Olu-087781	Ostreococcus lucimarinus	43.10	1.00e-11	61.60
IUUC-Oga-087987	Otolemur garnettii	65.52	4.00e-43	168.00
IUUC-Oar-090272	Ovis aries	75.26	1.00e-43	170.00
IUUC-Ptr-091566	Pan troglodytes	75.26	9.00e-44	170.00
IUUC-Pan-091884	Papio anubis	75.26	8.00e-44	170.00
IUUC-Psi-093539	Pelodiscus sinensis	69.72	7.00e-44	170.00
IUUC-Ppa-095927	Physcomitrella patens	32.79	4.00e-16	78.20
IUUC-Pfo-096604	Poecilia formosa	53.14	2.00e-47	182.00
IUUC-Pab-098694	Pongo abelii	75.26	1.00e-43	169.00
IUUC-Pop-099843	Populus trichocarpa	38.89	5.00e-17	80.90
IUUC-Pca-100961	Procavia capensis	63.79	6.00e-42	164.00
IUUC-Ppe-102055	Prunus persica	35.78	2.00e-15	75.10
IUUC-Pva-102987	Pteropus vampyrus	73.91	3.00e-41	161.00
IUUC-Pte-104131	Pyrenophora teres	33.03	1.00e-13	71.20
IUUC-Pyt-104807	Pyrenophora triticirepentis	33.03	9.00e-14	70.90
IUUC-Rno-105434	Rattus norvegicus	65.81	7.00e-44	170.00
IUUC-Sha-107023	Sarcophilus harrisii	67.23	2.00e-44	172.00
IUUC-Sit-109831	Setaria italica	37.36	4.00e-16	78.20
IUUC-Sly-111133	Solanum lycopersicum	38.14	7.00e-16	77.80
IUUC-Stu-112868	Solanum tuberosum	38.14	9.00e-16	77.40
IUUC-Sar-112966	Sorex araneus	75.26	8.00e-44	170.00
IUUC-Sbi-114233	Sorghum bicolor	26.92	4.00e-15	75.50
IUUC-Sre-114942	Sporisorium reilianum	28.67	9.00e-12	65.10
IUUC-Ssc-115502	Sus scrofa	75.26	8.00e-44	170.00
IUUC-Tgu-117430	Taeniopygia guttata	66.67	7.00e-43	167.00
IUUC-Tru-117715	Takifugu rubripes	65.87	2.00e-45	176.00
IUUC-Tsy-118844	Tarsius syrichta	56.70	5.00e-28	118.00
IUUC-Tni-119691	Tetraodon nigroviridis	65.87	1.00e-45	176.00
IUUC-Tca-121858	Theobroma cacao	39.56	2.00e-16	79.30
IUUC-Tae-123101	Triticum aestivum	35.16	8.00e-16	77.00
IUUC-Tur-126249	Triticum urartu	34.07	1.00e-14	72.40
IUUC-Tme-127191	Tuber melanosporum	34.74	6.00e-13	68.60
IUUC-Tbe-127237	Tupaia belangeri	75.26	2.00e-43	169.00
IUUC-Ttr-128179	Tursiops truncatus	63.79	4.00e-42	164.00
IUUC-Vpa-130240	Vicugna pacos	69.72	1.00e-43	169.00
IUUC-Vvi-131462	Vitis vinifera	40.00	1.00e-17	82.80
IUUC-Xtr-132852	Xenopus tropicalis	67.52	7.00e-43	167.00
IUUC-Xma-133395	Xiphophorus maculatus	53.14	2.00e-47	183.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence