iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	miRNAMap	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.30e-17	61.6	375	406

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           Ht+ +t++++  + +llv+++ + +i++WD+r+
   Q: 375  HTG-ITAMHLqETlGLLVTSGQNRVIMIWDVRS 406
           666.999999755799**************986 PP

Organism

Caenorhabditis elegans

Functional Description
(View)

Plays a role in coelomocyte endocytosis.

Protein Sequence
(Fasta)

MAAIINQRVE QGESSMGGAK PALLHRITGH VARINDVILL SKDEGVWTAS DDRSVRLYLK 60
RDNDQFWPSI HHFMPVAPTS LYYSEETYKL LVGLINGNVY EFSVADDFNS MTESRKWTCH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTTCAGCC ATTATGGCTG CAATAATCAA TCAACGCGTC GAACAGGGCG AATCAAGTAT 60
GGGAGGAGCC AAACCAGGTT GGTGAATTGA AAACGAACCA TTTGATTTCC ATAACCTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0254--Endocytosis
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR000306--Znf_FYVE
IPR017455--Znf_FYVE-rel
IPR011011--Znf_FYVE_PHD
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50178--ZF_FYVE

Pfam

PF01363--FYVE
PF00400--WD40

SMART

SM00064--FYVE
SM00320--WD40

Gene Ontology

GO:0046872--F:metal ion binding
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0006897--P:endocytosis

KEGG

cel:CELE_D2013.2

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002074	Ailuropoda melanoleuca	41.58	2.00e-99	354.00
IUUC-Apl-003661	Anas platyrhynchos	39.73	8.00e-87	312.00
IUUC-Aca-004902	Anolis carolinensis	41.33	3.00e-96	343.00
IUUC-Ame-010837	Astyanax mexicanus	41.61	3.00e-100	357.00
IUUC-Bta-012602	Bos taurus	38.61	9.00e-95	338.00
IUUC-Cja-019949	Callithrix jacchus	42.09	9.00e-101	358.00
IUUC-Cfa-020057	Canis familiaris	41.78	2.00e-90	324.00
IUUC-Cpo-022446	Cavia porcellus	42.09	1.00e-100	358.00
IUUC-Csa-023138	Chlorocebus sabaeus	42.09	1.00e-100	358.00
IUUC-Cho-024545	Choloepus hoffmanni	38.74	3.00e-83	300.00
IUUC-Cin-025573	Ciona intestinalis	38.59	2.00e-89	321.00
IUUC-Csv-026091	Ciona savignyi	37.29	2.00e-89	321.00
IUUC-Dre-027501	Danio rerio	43.07	7.00e-104	369.00
IUUC-Dno-029611	Dasypus novemcinctus	41.58	4.00e-99	353.00
IUUC-Dor-030500	Dipodomys ordii	39.60	9.00e-69	251.00
IUUC-Dme-031869	Drosophila melanogaster	36.92	4.00e-83	300.00
IUUC-Ete-032870	Echinops telfairi	34.74	3.00e-61	227.00
IUUC-Eca-033811	Equus caballus	42.09	1.00e-100	358.00
IUUC-Eeu-034637	Erinaceus europaeus	38.52	7.00e-85	306.00
IUUC-Fca-036212	Felis catus	39.45	3.00e-86	310.00
IUUC-Fal-037595	Ficedula albicollis	38.85	1.00e-94	338.00
IUUC-Gmo-039257	Gadus morhua	40.82	3.00e-97	347.00
IUUC-Gga-040902	Gallus gallus	42.09	6.00e-99	352.00
IUUC-Gac-042268	Gasterosteus aculeatus	39.39	8.00e-94	335.00
IUUC-Ggo-044590	Gorilla gorilla	42.09	3.00e-100	357.00
IUUC-Hsa-045692	Homo sapiens	41.58	6.00e-100	356.00
IUUC-Itr-049053	Ictidomys tridecemlineatus	42.09	2.00e-100	357.00
IUUC-Lch-049995	Latimeria chalumnae	39.81	5.00e-96	343.00
IUUC-Loc-052370	Lepisosteus oculatus	42.50	3.00e-101	360.00
IUUC-Laf-054594	Loxodonta africana	42.09	4.00e-100	357.00
IUUC-Mcc-055293	Macaca mulatta	39.33	3.00e-95	340.00
IUUC-Meu-056323	Macropus eugenii	41.88	8.00e-98	348.00
IUUC-Mga-060043	Meleagris gallopavo	42.06	2.00e-89	321.00
IUUC-Mmr-061268	Microcebus murinus	38.85	1.00e-95	341.00
IUUC-Mdo-062455	Monodelphis domestica	42.35	9.00e-101	358.00
IUUC-Mmu-064270	Mus musculus	41.84	3.00e-100	357.00
IUUC-Mpu-066391	Mustela putorius furo	39.33	2.00e-95	341.00
IUUC-Mlu-067636	Myotis lucifugus	39.73	9.00e-86	308.00
IUUC-Nle-069796	Nomascus leucogenys	42.09	2.00e-100	358.00
IUUC-Opr-071092	Ochotona princeps	41.58	5.00e-99	353.00
IUUC-Ont-072372	Oreochromis niloticus	42.09	1.00e-100	358.00
IUUC-Oan-073463	Ornithorhynchus anatinus	41.12	3.00e-81	293.00
IUUC-Ocu-074804	Oryctolagus cuniculus	42.09	1.00e-100	358.00
IUUC-Ola-087030	Oryzias latipes	39.09	7.00e-95	339.00
IUUC-Oga-087962	Otolemur garnettii	39.73	6.00e-87	312.00
IUUC-Oar-089827	Ovis aries	41.84	9.00e-100	355.00
IUUC-Ptr-091426	Pan troglodytes	42.09	2.00e-100	357.00
IUUC-Pan-092130	Papio anubis	39.81	7.00e-97	345.00
IUUC-Psi-093305	Pelodiscus sinensis	41.56	2.00e-95	341.00
IUUC-Pfo-096834	Poecilia formosa	40.83	1.00e-98	352.00
IUUC-Pab-098398	Pongo abelii	42.09	2.00e-100	357.00
IUUC-Pca-100741	Procavia capensis	36.26	7.00e-72	262.00
IUUC-Pva-102773	Pteropus vampyrus	41.84	1.00e-100	358.00
IUUC-Rno-104983	Rattus norvegicus	41.58	6.00e-100	356.00
IUUC-Sha-107407	Sarcophilus harrisii	42.86	2.00e-101	361.00
IUUC-Sar-113400	Sorex araneus	35.47	6.00e-49	186.00
IUUC-Ssc-115316	Sus scrofa	44.08	6.00e-52	196.00
IUUC-Tgu-116478	Taeniopygia guttata	42.09	7.00e-99	352.00
IUUC-Tru-118438	Takifugu rubripes	40.82	3.00e-97	347.00
IUUC-Tsy-119319	Tarsius syrichta	41.84	1.00e-98	351.00
IUUC-Tni-120051	Tetraodon nigroviridis	41.33	7.00e-100	355.00
IUUC-Tbe-127442	Tupaia belangeri	39.01	4.00e-85	306.00
IUUC-Ttr-129137	Tursiops truncatus	37.76	6.00e-86	309.00
IUUC-Vpa-130398	Vicugna pacos	43.02	2.00e-69	254.00
IUUC-Xtr-132445	Xenopus tropicalis	41.33	3.00e-97	347.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence