• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Details
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Dme-031594
UUCD1 version UUC-DrM-00545
Ensembl Protein ID FBpp0302691
UniProt Accession P25867; Q9VFG6; UBCD1_DROME
Genbank Protein ID CAA44453.1; AAF55093.1; AAL25343.1; AAB39622.1
Protein Name Ubiquitin-conjugating enzyme E2-17 kDa; E2 ubiquitin-conjugating enzyme D1; Protein effete; Ubiquitin carrier protein; Ubiquitin-protein ligase
Genbank Nucleotide ID X62575; AE014297; AY060304; U68298
Gene Name eff; UbcD1; CG7425
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0011217 FBtr0310554 FBpp0302691
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
Status Reviewed
Details
Family Domain References (PMIDs)
E2/UBC E2_UBC 19906849; 19077536; 17205079; 9267026
Classification
Family E-value Score Start End
E2/UBC 2.10e-56 189.6 5 139
UBD/UBC-like/UBD_UBC 9.40e-84 278.5 5 142
Active Site
Position(s) Description Evidence
85 Glycyl thioester intermediate {ECO:0000255|PROSITE-ProRule:PRU00388,
ECO:0000255|PROSITE-ProRule:PRU10133}
Domain Profile

   E2/UBC
   S: 1    RlkkelkelekdppegisakpvdesdltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsv 98
           R++kel++l +dpp+++sa+pv + dl++w+++i+Gp+d+pY+ggvF l+i+fp+dYPfkPPkv f+t+i+hPn+++nG++Cl+il+  ++Wspal++
   Q: 5    RINKELQDLGRDPPAQCSAGPVGD-DLFHWQATIMGPPDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILR--SQWSPALTI 99
           89**********************.9************************************************************9..********* PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkvr 138
           ++vllsi+sll++pnp++pl  e+a+++k++re+y++ +r
   Q: 100  SKVLLSICSLLCDPNPDDPLVPEIARIYKTDREKYNELAR 139
           ************************************9987 PP
   

   UBD/UBC-like/UBD_UBC
   S: 1    rikkelkdllrdeeaqisadlvdddlfelratiagppdspyeggvffltiklptdypfkppkvafitkiyhpninsngsicldilrsqwsaaltlskv 98
           ri+kel+dl rd++aq+sa++v+ddlf+++ati+gppdspy+ggvfflti++ptdypfkppkvaf+t+iyhpninsngsicldilrsqws+alt+skv
   Q: 5    RINKELQDLGRDPPAQCSAGPVGDDLFHWQATIMGPPDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKV 102
           8************************************************************************************************* PP
   S: 99   llslcslladaepddplvaeiariyktdkekykriarewt 138
           lls+csll+d++pddplv+eiariyktd+eky++ arewt
   Q: 103  LLSICSLLCDPNPDDPLVPEIARIYKTDREKYNELAREWT 142
           ***************************************8 PP
   
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Required for proper telomere behavior during cell divisions and possibly for ubiquitination of proteins involved in postmeiotic stages of spermatogenesis. Deletion mutations are lethal in homozygotes.
 Catalyzes the covalent attachment of ubiquitin to other proteins. Mediates the selective degradation of short-lived and abnormal proteins. Required for proper telomere behavior during cell divisions and possibly for ubiquitination of proteins involved in postmeiotic stages of spermatogenesis. Deletion mutations are lethal in homozygotes.
Protein Sequence
(Fasta)
MALKRINKEL QDLGRDPPAQ CSAGPVGDDL FHWQATIMGP PDSPYQGGVF FLTIHFPTDY 60
PFKPPKVAFT TRIYHPNINS NGSICLDILR SQWSPALTIS KVLLSICSLL CDPNPDDPLV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-031594|E2,E2/UBC;UBD,UBD_UBC|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATCCTGAATT GGCACGTCGG CCTTGCCAGA CCAGCGCTCT GGAGTGAATT TAAATTTTAA 60
AATAACGCCC TGTCAATTCA GTTGTAGAAC TCAGTAGCTA GTCGGAAAGT TTTCAAGAAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031594|E2,E2/UBC;UBD,UBD_UBC|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0469--Meiosis
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD
PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2
Pfam

PF00179--UQ_con
Gene Ontology

GO:0005875--C:microtubule associated complex
GO:0005524--F:ATP binding
GO:0061631--F:ubiquitin conjugating enzyme activity
GO:0061630--F:ubiquitin protein ligase activity
GO:0031625--F:ubiquitin protein ligase binding
GO:0031145--P:anaphase-promoting complex-dependent catabolic process
GO:0051276--P:chromosome organization
GO:0001745--P:compound eye morphogenesis
GO:0001751--P:compound eye photoreceptor cell differentiation
GO:0048132--P:female germ-line stem cell asymmetric division
GO:0030718--P:germ-line stem cell population maintenance
GO:0007140--P:male meiosis
GO:0007067--P:mitotic nuclear division
GO:0022008--P:neurogenesis
GO:0016322--P:neuron remodeling
GO:0097039--P:protein linear polyubiquitination
GO:0000209--P:protein polyubiquitination
GO:0016567--P:protein ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031647--P:regulation of protein stability
GO:0045676--P:regulation of R7 cell differentiation
GO:0007286--P:spermatid development
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG dme:Dmel_CG7425
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000142 Aegilops tauschii 78.91 2.00e-69 253.00
IUUC-Aml-001563 Ailuropoda melanoleuca 89.12 3.00e-78 282.00
IUUC-Atr-002782 Amborella trichopoda 80.27 3.00e-70 255.00
IUUC-Apl-004043 Anas platyrhynchos 91.84 4.00e-79 285.00
IUUC-Aca-005236 Anolis carolinensis 94.56 1.00e-81 293.00
IUUC-Aly-006221 Arabidopsis lyrata 80.27 7.00e-71 258.00
IUUC-Ath-007700 Arabidopsis thaliana 80.27 5.00e-70 255.00
IUUC-Ago-007967 Ashbya gossypii 82.31 3.00e-73 265.00
IUUC-Acl-008266 Aspergillus clavatus 87.76 9.00e-76 274.00
IUUC-Afl-008709 Aspergillus flavus 80.28 8.00e-69 253.00
IUUC-Afu-008956 Aspergillus fumigatus 88.44 4.00e-76 275.00
IUUC-Ani-009401 Aspergillus nidulans 86.39 1.00e-74 270.00
IUUC-Ang-009725 Aspergillus niger 86.40 1.00e-62 231.00
IUUC-Aor-010157 Aspergillus oryzae 87.07 2.00e-75 273.00
IUUC-Ate-010438 Aspergillus terreus 87.07 5.00e-75 271.00
IUUC-Ame-011657 Astyanax mexicanus 95.89 3.00e-81 292.00
IUUC-Bgr-012238 Blumeria graminis 81.63 7.00e-71 258.00
IUUC-Bta-013158 Bos taurus 94.56 1.00e-81 293.00
IUUC-Bci-013661 Botrytis cinerea 86.39 7.00e-76 274.00
IUUC-Bdi-014561 Brachypodium distachyon 78.91 7.00e-70 254.00
IUUC-Bol-015722 Brassica oleracea 80.95 1.00e-70 257.00
IUUC-Bra-017985 Brassica rapa 80.27 1.00e-70 257.00
IUUC-Cel-018362 Caenorhabditis elegans 96.60 1.00e-83 300.00
IUUC-Cja-019886 Callithrix jacchus 94.56 1.00e-81 293.00
IUUC-Cfa-020436 Canis familiaris 94.56 1.00e-81 293.00
IUUC-Cpo-021714 Cavia porcellus 92.52 7.00e-80 288.00
IUUC-Cre-022765 Chlamydomonas reinhardtii 81.63 7.00e-71 258.00
IUUC-Csa-023668 Chlorocebus sabaeus 89.12 3.00e-78 282.00
IUUC-Cho-024987 Choloepus hoffmanni 89.12 3.00e-78 282.00
IUUC-Cin-025379 Ciona intestinalis 89.04 3.00e-78 282.00
IUUC-Csv-025835 Ciona savignyi 83.56 8.00e-65 238.00
IUUC-Cgl-026490 Colletotrichum gloeosporioides 87.07 2.00e-75 273.00
IUUC-Cne-026957 Cryptococcus neoformans 82.88 1.00e-71 260.00
IUUC-Cme-027220 Cyanidioschyzon merolae 86.39 2.00e-74 270.00
IUUC-Dre-027758 Danio rerio 95.24 3.00e-82 296.00
IUUC-Dno-028952 Dasypus novemcinctus 95.00 3.00e-78 282.00
IUUC-Dor-030323 Dipodomys ordii 91.84 2.00e-79 286.00
IUUC-Dse-031397 Dothistroma septosporum 87.07 1.00e-75 274.00
IUUC-Ete-032540 Echinops telfairi 89.12 3.00e-78 282.00
IUUC-Eca-034167 Equus caballus 89.12 3.00e-78 282.00
IUUC-Eeu-034766 Erinaceus europaeus 94.29 7.00e-76 274.00
IUUC-Fca-035917 Felis catus 93.88 2.00e-81 293.00
IUUC-Fal-036904 Ficedula albicollis 93.57 3.00e-77 279.00
IUUC-Fox-038021 Fusarium oxysporum 87.07 3.00e-75 272.00
IUUC-Fso-038297 Fusarium solani 86.39 7.00e-75 271.00
IUUC-Gmo-038898 Gadus morhua 93.71 1.00e-78 283.00
IUUC-Ggr-039912 Gaeumannomyces graminis 82.24 3.00e-71 259.00
IUUC-Gga-041015 Gallus gallus 95.24 5.00e-82 295.00
IUUC-Gac-042516 Gasterosteus aculeatus 93.20 8.00e-80 287.00
IUUC-Gma-043923 Glycine max 80.27 3.00e-70 256.00
IUUC-Ggo-045361 Gorilla gorilla 92.52 1.00e-79 287.00
IUUC-Hsa-045885 Homo sapiens 94.56 1.00e-81 293.00
IUUC-Hvu-047546 Hordeum vulgare 76.87 6.00e-68 248.00
IUUC-Itr-048882 Ictidomys tridecemlineatus 92.57 4.00e-79 285.00
IUUC-Kpa-049290 Komagataella pastoris 80.95 1.00e-71 260.00
IUUC-Lch-050109 Latimeria chalumnae 87.76 2.00e-77 279.00
IUUC-Lpe-051194 Leersia perrieri 78.91 2.00e-69 254.00
IUUC-Loc-052838 Lepisosteus oculatus 92.52 1.00e-79 287.00
IUUC-Lma-053121 Leptosphaeria maculans 87.07 5.00e-76 275.00
IUUC-Laf-053580 Loxodonta africana 95.00 4.00e-78 282.00
IUUC-Mcc-055421 Macaca mulatta 92.52 1.00e-79 287.00
IUUC-Meu-056462 Macropus eugenii 92.09 1.00e-75 273.00
IUUC-Mor-057235 Magnaporthe oryzae 86.39 7.00e-75 271.00
IUUC-Mpo-057596 Magnaporthe poae 82.24 7.00e-71 258.00
IUUC-Mtr-058532 Medicago truncatula 78.91 4.00e-69 252.00
IUUC-Mla-059189 Melampsora laricipopulina 82.31 3.00e-70 256.00
IUUC-Mga-059237 Meleagris gallopavo 93.57 4.00e-77 278.00
IUUC-Mvi-060397 Microbotryum violaceum 83.67 5.00e-73 265.00
IUUC-Mmr-060889 Microcebus murinus 95.24 5.00e-82 295.00
IUUC-Mdo-062962 Monodelphis domestica 94.56 1.00e-81 293.00
IUUC-Mmu-063796 Mus musculus 95.24 5.00e-82 295.00
IUUC-Mac-065211 Musa acuminata 80.27 3.00e-70 256.00
IUUC-Mpu-066604 Mustela putorius furo 91.10 9.00e-79 284.00
IUUC-Mlu-067573 Myotis lucifugus 88.57 2.00e-74 269.00
IUUC-Nfi-068599 Neosartorya fischeri 88.44 4.00e-76 275.00
IUUC-Ncr-068677 Neurospora crassa 85.71 2.00e-74 270.00
IUUC-Nle-069715 Nomascus leucogenys 92.52 1.00e-79 287.00
IUUC-Opr-070191 Ochotona princeps 93.53 1.00e-76 276.00
IUUC-Ont-071766 Oreochromis niloticus 93.88 3.00e-81 292.00
IUUC-Oan-073026 Ornithorhynchus anatinus 91.49 9.00e-76 275.00
IUUC-Ocu-074315 Oryctolagus cuniculus 94.56 1.00e-81 293.00
IUUC-Oba-075411 Oryza barthii 78.91 2.00e-69 253.00
IUUC-Obr-076658 Oryza brachyantha 78.91 2.00e-69 253.00
IUUC-Ogl-076968 Oryza glaberrima 79.59 6.00e-70 254.00
IUUC-Ogu-078981 Oryza glumaepatula 78.91 2.00e-69 253.00
IUUC-Oin-079659 Oryza indica 79.59 6.00e-70 254.00
IUUC-Olo-080786 Oryza longistaminata 78.91 2.00e-69 253.00
IUUC-Ome-081967 Oryza meridionalis 78.91 4.00e-69 252.00
IUUC-Oni-082391 Oryza nivara 79.59 6.00e-70 256.00
IUUC-Opu-083833 Oryza punctata 78.91 3.00e-69 253.00
IUUC-Oru-085167 Oryza rufipogon 79.59 8.00e-70 256.00
IUUC-Osa-086003 Oryza sativa 79.59 6.00e-70 254.00
IUUC-Ola-086331 Oryzias latipes 93.88 3.00e-81 292.00
IUUC-Olu-087615 Ostreococcus lucimarinus 78.23 1.00e-66 244.00
IUUC-Oga-088477 Otolemur garnettii 92.47 1.00e-79 287.00
IUUC-Oar-090038 Ovis aries 93.88 2.00e-81 293.00
IUUC-Ptr-090707 Pan troglodytes 94.56 1.00e-81 293.00
IUUC-Pan-092143 Papio anubis 94.56 1.00e-81 293.00
IUUC-Psi-094076 Pelodiscus sinensis 93.88 2.00e-81 293.00
IUUC-Pma-094405 Petromyzon marinus 94.81 3.00e-74 269.00
IUUC-Pno-094765 Phaeosphaeria nodorum 87.07 5.00e-76 275.00
IUUC-Ppa-095564 Physcomitrella patens 80.27 3.00e-70 256.00
IUUC-Pfo-096753 Poecilia formosa 93.88 3.00e-81 292.00
IUUC-Pab-097764 Pongo abelii 94.56 1.00e-81 293.00
IUUC-Pop-099586 Populus trichocarpa 80.27 4.00e-70 255.00
IUUC-Pca-100678 Procavia capensis 89.12 3.00e-78 282.00
IUUC-Ppe-101431 Prunus persica 80.95 8.00e-71 258.00
IUUC-Pva-102770 Pteropus vampyrus 89.12 3.00e-78 282.00
IUUC-Pgr-103381 Puccinia graminis 83.67 7.00e-71 259.00
IUUC-Ptt-103723 Puccinia triticina 79.29 2.00e-62 230.00
IUUC-Pte-104015 Pyrenophora teres 87.07 9.00e-76 274.00
IUUC-Pyt-104701 Pyrenophora triticirepentis 87.07 9.00e-76 274.00
IUUC-Rno-105498 Rattus norvegicus 93.88 2.00e-81 293.00
IUUC-Sce-106153 Saccharomyces cerevisiae 81.94 6.00e-71 258.00
IUUC-Sha-106489 Sarcophilus harrisii 85.52 3.00e-75 272.00
IUUC-Sja-107729 Schizosaccharomyces japonicus 87.07 3.00e-75 272.00
IUUC-Spo-108032 Schizosaccharomyces pombe 87.07 3.00e-75 272.00
IUUC-Ssl-108443 Sclerotinia sclerotiorum 87.07 3.00e-76 276.00
IUUC-Smo-109317 Selaginella moellendorffii 80.27 4.00e-70 255.00
IUUC-Sit-109936 Setaria italica 78.23 2.00e-69 254.00
IUUC-Sly-111055 Solanum lycopersicum 80.95 7.00e-71 258.00
IUUC-Stu-112192 Solanum tuberosum 80.95 2.00e-70 256.00
IUUC-Sar-113302 Sorex araneus 94.96 2.00e-77 279.00
IUUC-Sbi-114840 Sorghum bicolor 79.59 5.00e-70 255.00
IUUC-Sre-115037 Sporisorium reilianum 81.94 6.00e-71 258.00
IUUC-Ssc-115391 Sus scrofa 92.52 1.00e-79 287.00
IUUC-Tgu-116727 Taeniopygia guttata 93.88 2.00e-81 293.00
IUUC-Tru-118272 Takifugu rubripes 93.88 8.00e-81 291.00
IUUC-Tsy-118832 Tarsius syrichta 89.80 1.00e-76 277.00
IUUC-Tni-120056 Tetraodon nigroviridis 93.88 8.00e-81 291.00
IUUC-Tca-121413 Theobroma cacao 80.27 3.00e-70 256.00
IUUC-Tre-122125 Trichoderma reesei 85.03 2.00e-73 266.00
IUUC-Tvi-122296 Trichoderma virens 85.03 2.00e-73 266.00
IUUC-Tae-123340 Triticum aestivum 80.27 7.00e-71 258.00
IUUC-Tur-126518 Triticum urartu 78.91 4.00e-70 256.00
IUUC-Tme-126912 Tuber melanosporum 84.35 9.00e-74 267.00
IUUC-Tbe-128122 Tupaia belangeri 91.13 4.00e-57 212.00
IUUC-Ttr-128363 Tursiops truncatus 89.12 3.00e-78 282.00
IUUC-Uma-129648 Ustilago maydis 82.99 8.00e-73 264.00
IUUC-Vda-129695 Verticillium dahliae 87.07 2.00e-75 273.00
IUUC-Vpa-130446 Vicugna pacos 94.29 2.00e-76 278.00
IUUC-Vvi-131016 Vitis vinifera 79.59 3.00e-70 256.00
IUUC-Xtr-132329 Xenopus tropicalis 94.56 1.00e-81 293.00
IUUC-Xma-133829 Xiphophorus maculatus 93.88 3.00e-81 292.00
IUUC-Yli-134353 Yarrowia lipolytica 80.95 2.00e-72 263.00
IUUC-Zma-135569 Zea mays 78.91 2.00e-69 253.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved