iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	1.10e-07	32.1	32	78

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 101  glldrlpeeilveilklldkeellraarvcrrwqelasqkalwktvt 147
           +++++lp+++l++i+++l+++e++r+ar+crrw+++a +++lwk+v 
   Q: 32   TTIEKLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKNVS 78
           57899*****************************99999*****986 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MDISTDIWGQ LAVEASQVYL SDGTVRSPFA DTTIEKLPDK VLLHIFSYLS HREICRLARI 60
CRRWRQIAYD TRLWKNVSLR PEVSGLHVGS LEMLLQLISV RFGPTLRYIE LPIELITHTV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTTTTCTC AGAGTTGTGG AGCCGTCGAG AACGCGGAGC ATTCGCCCAT GTAAAGCCGC 60
AGAATCCGTC GATTTTCGCC GGAATTTATC AATCCGATTT GCCAGTAATT TGCAACAGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like

SMART

SM00256--FBOX

Gene Ontology

GO:0019005--C:SCF ubiquitin ligase complex
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cel-018421	Caenorhabditis elegans	50.31	1.00e-136	478.00
IUUC-Csa-024146	Chlorocebus sabaeus	33.82	2.00e-11	62.00
IUUC-Cin-025189	Ciona intestinalis	46.67	6.00e-08	50.40
IUUC-Cme-027297	Cyanidioschyzon merolae	37.50	6.00e-06	44.70
IUUC-Dno-028860	Dasypus novemcinctus	34.51	2.00e-11	62.80
IUUC-Ete-032314	Echinops telfairi	43.48	3.00e-07	49.70
IUUC-Eeu-035297	Erinaceus europaeus	38.39	3.00e-13	68.20
IUUC-Ggo-044537	Gorilla gorilla	32.65	3.00e-11	62.00
IUUC-Hsa-046340	Homo sapiens	33.82	2.00e-11	62.00
IUUC-Mcc-055154	Macaca mulatta	33.09	3.00e-11	62.00
IUUC-Mdo-062488	Monodelphis domestica	33.91	3.00e-13	67.80
IUUC-Nle-069785	Nomascus leucogenys	33.82	2.00e-11	62.00
IUUC-Ogu-078253	Oryza glumaepatula	35.59	1.00e-03	39.70
IUUC-Ptr-090775	Pan troglodytes	33.82	2.00e-11	62.00
IUUC-Pan-092039	Papio anubis	33.09	3.00e-11	62.00
IUUC-Pab-098147	Pongo abelii	33.09	3.00e-11	61.60
IUUC-Sha-107634	Sarcophilus harrisii	31.39	6.00e-12	63.50
IUUC-Stu-111936	Solanum tuberosum	41.46	6.00e-06	42.70

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence