iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Cancer Mutation
TCGA	COSMIC	CGAP	IntOGen
mRNA Expression
ArrayExpress	TCGA	ICGC	COSMIC
DNA & RNA Element
UTRdb	CircNet	RepTar	SomamiR
miRcode	RAID2
Disease-associated Variation
GWASdb
DNA Methylation
TCGA	ICGC	COSMIC
Protein Expression/Proteomics
THPA	GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	8.40e-12	46.9	57	119

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalf.lmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +Dv + v+g+ef+ah++vLaasS++F++   l+++ +        +   ++p++f+++l   Ytg+l++
   Q: 57   CDVSIRVQGREFRAHRAVLAASSPYFHDQVlLKGMTSI------SLPSvMDPGAFETVLASAYTGRLSM 119
           8***************************9845555544......3444578***************986 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MEPSPLSPSG AALPLPLSLA PPPLPLPAAA VVHVSFPEVT SALLESLNQQ RLQGQLCDVS 60
IRVQGREFRA HRAVLAASSP YFHDQVLLKG MTSISLPSVM DPGAFETVLA SAYTGRLSMA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATAAATGCT TCGGCCGAAC CAAGTCCTGA GCTCCCAGCG GAGGAGGGGA CCTGATCTTT 60
TAAGGTGGAA TGTGGCGATG TTTCTTTAAA GGCAAAGTGG CCGAGTCGGC CGAGTATTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR029833--ZBT22

PROSITE

PS50097--BTB

Pfam

PF00651--BTB

SMART

SM00225--BTB

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001767	Ailuropoda melanoleuca	93.62	0.00e+00	828.00
IUUC-Bta-013111	Bos taurus	87.46	0.00e+00	723.00
IUUC-Cja-019634	Callithrix jacchus	96.64	0.00e+00	771.00
IUUC-Cfa-020967	Canis familiaris	90.20	0.00e+00	817.00
IUUC-Cpo-021465	Cavia porcellus	85.91	0.00e+00	789.00
IUUC-Csa-023077	Chlorocebus sabaeus	98.49	0.00e+00	725.00
IUUC-Dor-030717	Dipodomys ordii	91.11	0.00e+00	777.00
IUUC-Eca-033663	Equus caballus	90.77	0.00e+00	805.00
IUUC-Ggo-045042	Gorilla gorilla	99.50	0.00e+00	826.00
IUUC-Itr-048252	Ictidomys tridecemlineatus	91.93	0.00e+00	802.00
IUUC-Laf-054437	Loxodonta africana	86.05	0.00e+00	703.00
IUUC-Mcc-054995	Macaca mulatta	98.75	0.00e+00	712.00
IUUC-Mmr-061368	Microcebus murinus	93.81	0.00e+00	749.00
IUUC-Mdo-062574	Monodelphis domestica	80.00	1.00e-91	330.00
IUUC-Mmu-064153	Mus musculus	84.88	0.00e+00	803.00
IUUC-Mpu-066306	Mustela putorius furo	93.30	0.00e+00	839.00
IUUC-Mlu-067446	Myotis lucifugus	88.87	0.00e+00	796.00
IUUC-Ocu-074392	Oryctolagus cuniculus	85.15	0.00e+00	693.00
IUUC-Oar-090241	Ovis aries	86.83	0.00e+00	722.00
IUUC-Ptr-091294	Pan troglodytes	99.66	0.00e+00	785.00
IUUC-Pan-091696	Papio anubis	80.43	2.00e-87	316.00
IUUC-Pfo-096385	Poecilia formosa	41.57	1.00e-53	205.00
IUUC-Pab-098065	Pongo abelii	98.99	0.00e+00	764.00
IUUC-Pca-100919	Procavia capensis	93.75	2.00e-83	303.00
IUUC-Pva-103075	Pteropus vampyrus	85.79	0.00e+00	738.00
IUUC-Rno-105534	Rattus norvegicus	84.60	0.00e+00	759.00
IUUC-Sha-106657	Sarcophilus harrisii	76.20	0.00e+00	650.00
IUUC-Ssc-115946	Sus scrofa	87.66	0.00e+00	731.00
IUUC-Ttr-129203	Tursiops truncatus	86.78	2.00e-145	508.00
IUUC-Xtr-131973	Xenopus tropicalis	50.00	1.00e-122	432.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence