iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066784

Ensembl Protein ID

ENSMPUP00000015595.1

UniProt Accession

M3YW85; M3YW85_MUSPF

Genbank Protein ID

ENSMPUP00000015595

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEYP01053125

Gene Name

GNB2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000015704.1	ENSMPUT00000015836.1	ENSMPUP00000015595.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-40	135.2	182	220
UBD/Beta-Prp	9.20e-53	179.3	47	268

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+++v +l++ +d +++vsG+ D +ik+WD+r+  + +
   Q: 182  GHSGDVMSLSLaPDgRTFVSGACDASIKLWDVRDSMCRQ 220
           8***********99999****************988866 PP

UBD/Beta-Prp

   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee. 131
           + r+l gh a+++a+ +  d+ +lv++s+D+ + +wd  t   vh++   ++ v+++++ psg++++ G+ d++  ++ l+t++     
   Q: 47   TRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGGLDNICSIYSLKTREGNVRv 135
           56899****************************************************************************99877666 PP
   S: 132  ..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtl 218
              l gh+g  +c ++ + +n ++++s D+t+ lWd++tg+    + g h ++v sls+ ++g+ +vsg++d ++klwd++ + c +t+
   Q: 136  srELPGHTGYLSCCRFLD-DNQIITSSGDTTCALWDIETGQQTVGFAG-HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTF 222
           779*************99.7778999********************99.**************************************** PP
   S: 219  nghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhn 264
           +gh++ ++ v+f+pn+  + +gs+D + r++dlr ++ l ++++ n
   Q: 223  IGHESDINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDN 268
           ***************************************9999854 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MSELEQLRQE AEQLRNQIRS PASSSPSSPA SEITAGLDPV GRIQMRTRRT LRGHLAKIYA 60
MHWGTDSRLL VSASQDGKLI IWDSYTTNKV HAIPLRSSWV MTCAYAPSGN FVACGGLDNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTGAGC TGGAGCAACT GAGACAGGAG GCTGAGCAGC TCCGGAACCA AATCCGGGTG 60
AGGGCCTGAC CGCGGGGCTG GGGAGGCTGA GCCGCCAGGG CCAGGTGGCC TAAATGGACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005615--C:extracellular space
GO:0005925--C:focal adhesion
GO:0005765--C:lysosomal membrane
GO:0043209--C:myelin sheath
GO:0048471--C:perinuclear region of cytoplasm
GO:0007165--P:signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001395	Ailuropoda melanoleuca	98.71	0.00e+00	630.00
IUUC-Ago-007831	Ashbya gossypii	37.98	2.00e-66	246.00
IUUC-Ame-011124	Astyanax mexicanus	90.59	6.00e-176	609.00
IUUC-Bta-013430	Bos taurus	99.68	0.00e+00	637.00
IUUC-Cja-019794	Callithrix jacchus	99.68	0.00e+00	637.00
IUUC-Cpo-021865	Cavia porcellus	99.68	0.00e+00	637.00
IUUC-Csa-023572	Chlorocebus sabaeus	99.68	0.00e+00	637.00
IUUC-Dre-027957	Danio rerio	93.85	3.00e-175	607.00
IUUC-Dno-029001	Dasypus novemcinctus	99.68	0.00e+00	637.00
IUUC-Dor-030322	Dipodomys ordii	88.03	5.00e-158	550.00
IUUC-Eca-034149	Equus caballus	99.68	0.00e+00	637.00
IUUC-Fca-036537	Felis catus	99.68	0.00e+00	637.00
IUUC-Ggr-039969	Gaeumannomyces graminis	64.33	4.00e-132	464.00
IUUC-Ggo-044543	Gorilla gorilla	99.68	0.00e+00	637.00
IUUC-Hsa-046432	Homo sapiens	99.68	0.00e+00	637.00
IUUC-Itr-048049	Ictidomys tridecemlineatus	96.40	0.00e+00	658.00
IUUC-Laf-053865	Loxodonta africana	99.68	0.00e+00	637.00
IUUC-Mcc-055781	Macaca mulatta	100.00	0.00e+00	632.00
IUUC-Meu-056902	Macropus eugenii	99.03	0.00e+00	634.00
IUUC-Mmr-061015	Microcebus murinus	99.68	0.00e+00	637.00
IUUC-Mdo-062734	Monodelphis domestica	99.03	0.00e+00	634.00
IUUC-Mmu-063737	Mus musculus	99.68	0.00e+00	636.00
IUUC-Mlu-067912	Myotis lucifugus	99.35	0.00e+00	636.00
IUUC-Opr-070866	Ochotona princeps	99.68	0.00e+00	637.00
IUUC-Ocu-074344	Oryctolagus cuniculus	99.68	0.00e+00	637.00
IUUC-Oga-089046	Otolemur garnettii	99.68	0.00e+00	637.00
IUUC-Ptr-091444	Pan troglodytes	99.68	0.00e+00	637.00
IUUC-Pan-092045	Papio anubis	99.68	0.00e+00	637.00
IUUC-Pma-094748	Petromyzon marinus	90.87	5.00e-139	486.00
IUUC-Pab-097601	Pongo abelii	98.71	0.00e+00	632.00
IUUC-Pca-100940	Procavia capensis	99.68	0.00e+00	637.00
IUUC-Pva-102229	Pteropus vampyrus	100.00	0.00e+00	638.00
IUUC-Rno-106104	Rattus norvegicus	99.68	0.00e+00	637.00
IUUC-Sha-107632	Sarcophilus harrisii	99.03	0.00e+00	634.00
IUUC-Ssc-115595	Sus scrofa	99.68	0.00e+00	637.00
IUUC-Tbe-128132	Tupaia belangeri	99.22	3.00e-148	517.00
IUUC-Ttr-128403	Tursiops truncatus	99.68	0.00e+00	637.00
IUUC-Vda-129855	Verticillium dahliae	70.16	5.00e-129	453.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence