iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ptr-091640

Ensembl Protein ID

ENSPTRP00000047790.4

UniProt Accession

H2R540; H2R540_PANTR

Genbank Protein ID

JAA21822.1; JAA44463.1; JAA44465.1

Protein Name

Sequestosome 1

Genbank Nucleotide ID

AACZ03043295; GABE01000276; GABE01000274

Gene Name

SQSTM1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000017626.6	ENSPTRT00000055318.4	ENSPTRP00000047790.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UFD/PB1	2.10e-18	66.3	22	102

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UFD/PB1

   S: 3    rvkvsykgeirsfaldlekpgkfedLlkavrt.ltelknsevalkYeDedGDlvtlksDedldkavsllaskksllrlliqkk 84
           r+ +++++e+++ a+++++pg +e+Ll++v++ +++l+   ++ +Y+DedGDlv+++sDe+l++a+s+   k++++r++i++k
   Q: 22   RFSFCFSPEPEAEAEAAAGPGPCERLLSRVAAlFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSY--VKDDIFRIYIKEK 102
           899*****************************999********************************7..9*********975 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MASLTVKAYL LGKEDAAREI RRFSFCFSPE PEAEAEAAAG PGPCERLLSR VAALFPALRP 60
GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK EKKECRRDHR PPCAQEAPRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTCTCGAGG CGGGGCGGGG CCTCCGCGTT CGCTACAAAA GCCGCGCGTC GGCTGCGACC 60
GGGACGGCCC GTTTTCTGCC AGCTCGCCGC TCGCTATGGC GTCGCTCACC GTGAAGGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000270--PB1_dom
IPR033741--SQSTM_UBA
IPR015940--UBA
IPR009060--UBA-like
IPR000433--Znf_ZZ

PROSITE

PS51745--PB1
PS50030--UBA
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2

Pfam

PF00564--PB1
PF16577--UBA_5
PF00569--ZZ

SMART

SM00666--PB1
SM00165--UBA
SM00291--ZnF_ZZ

Gene Ontology

GO:0016235--C:aggresome
GO:0044753--C:amphisome
GO:0044754--C:autolysosome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0000932--C:P-body
GO:0016605--C:PML body
GO:0000407--C:pre-autophagosomal structure
GO:0097225--C:sperm midpiece
GO:0042802--F:identical protein binding
GO:0043130--F:ubiquitin binding
GO:0008270--F:zinc ion binding
GO:0006914--P:autophagy
GO:0044130--P:negative regulation of growth of symbiont in host
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016239--P:positive regulation of macroautophagy
GO:0098779--P:positive regulation of macromitophagy in response to mitochondrial depolarization
GO:0043122--P:regulation of I-kappaB kinase/NF-kappaB signaling
GO:0061635--P:regulation of protein complex stability
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

ptr:462333

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001367	Ailuropoda melanoleuca	90.86	1.00e-169	588.00
IUUC-Apl-003897	Anas platyrhynchos	59.06	3.00e-116	411.00
IUUC-Aca-004699	Anolis carolinensis	47.81	9.00e-95	340.00
IUUC-Ame-010982	Astyanax mexicanus	45.37	1.00e-65	244.00
IUUC-Bta-012634	Bos taurus	92.27	0.00e+00	753.00
IUUC-Cel-018660	Caenorhabditis elegans	50.00	8.00e-11	59.70
IUUC-Cja-019684	Callithrix jacchus	94.77	0.00e+00	757.00
IUUC-Cfa-020573	Canis familiaris	84.66	2.00e-136	478.00
IUUC-Cpo-021425	Cavia porcellus	79.73	7.00e-176	609.00
IUUC-Csa-023968	Chlorocebus sabaeus	96.82	0.00e+00	754.00
IUUC-Cho-024596	Choloepus hoffmanni	85.81	1.00e-51	196.00
IUUC-Cin-025557	Ciona intestinalis	34.15	2.00e-12	66.60
IUUC-Csv-025974	Ciona savignyi	25.77	8.00e-13	67.80
IUUC-Dre-028621	Danio rerio	43.91	3.00e-95	342.00
IUUC-Dno-029060	Dasypus novemcinctus	88.74	0.00e+00	731.00
IUUC-Dor-030547	Dipodomys ordii	89.74	2.00e-136	479.00
IUUC-Ete-033201	Echinops telfairi	79.36	6.00e-163	566.00
IUUC-Eca-033456	Equus caballus	90.86	0.00e+00	677.00
IUUC-Eeu-035157	Erinaceus europaeus	81.28	1.00e-170	592.00
IUUC-Fca-035403	Felis catus	90.77	0.00e+00	706.00
IUUC-Fal-036798	Ficedula albicollis	57.14	5.00e-134	470.00
IUUC-Gmo-039619	Gadus morhua	40.96	1.00e-47	182.00
IUUC-Gga-040137	Gallus gallus	57.78	6.00e-133	467.00
IUUC-Gac-042410	Gasterosteus aculeatus	45.39	3.00e-95	342.00
IUUC-Ggo-044690	Gorilla gorilla	99.55	0.00e+00	768.00
IUUC-Hsa-046390	Homo sapiens	99.77	0.00e+00	766.00
IUUC-Itr-048536	Ictidomys tridecemlineatus	93.64	0.00e+00	777.00
IUUC-Lch-049658	Latimeria chalumnae	47.29	2.00e-110	392.00
IUUC-Loc-052589	Lepisosteus oculatus	47.70	2.00e-109	389.00
IUUC-Laf-053746	Loxodonta africana	82.51	0.00e+00	648.00
IUUC-Mcc-055635	Macaca mulatta	95.91	0.00e+00	768.00
IUUC-Meu-056528	Macropus eugenii	51.00	2.00e-100	358.00
IUUC-Mga-059458	Meleagris gallopavo	59.65	7.00e-119	420.00
IUUC-Mvi-060347	Microbotryum violaceum	54.05	1.00e-07	52.40
IUUC-Mmr-061539	Microcebus murinus	91.17	4.00e-141	493.00
IUUC-Mdo-063083	Monodelphis domestica	64.98	6.00e-150	523.00
IUUC-Mmu-063589	Mus musculus	90.05	0.00e+00	744.00
IUUC-Mpu-065727	Mustela putorius furo	89.22	7.00e-180	622.00
IUUC-Mlu-067026	Myotis lucifugus	88.00	0.00e+00	630.00
IUUC-Nle-069356	Nomascus leucogenys	69.06	6.00e-130	457.00
IUUC-Opr-071091	Ochotona princeps	71.38	1.00e-94	340.00
IUUC-Ont-071864	Oreochromis niloticus	46.97	9.00e-102	363.00
IUUC-Oan-073308	Ornithorhynchus anatinus	64.52	2.00e-136	478.00
IUUC-Ocu-074110	Oryctolagus cuniculus	92.27	0.00e+00	739.00
IUUC-Ola-086944	Oryzias latipes	45.25	2.00e-40	158.00
IUUC-Oga-088869	Otolemur garnettii	92.15	0.00e+00	748.00
IUUC-Oar-089857	Ovis aries	93.07	0.00e+00	659.00
IUUC-Pan-092831	Papio anubis	96.86	0.00e+00	758.00
IUUC-Psi-093925	Pelodiscus sinensis	56.32	2.00e-125	441.00
IUUC-Pma-094576	Petromyzon marinus	30.95	6.00e-30	125.00
IUUC-Pfo-097297	Poecilia formosa	43.68	8.00e-90	323.00
IUUC-Pab-098725	Pongo abelii	87.27	0.00e+00	669.00
IUUC-Pca-101106	Procavia capensis	91.14	0.00e+00	714.00
IUUC-Pva-102710	Pteropus vampyrus	88.46	0.00e+00	645.00
IUUC-Rno-105539	Rattus norvegicus	89.37	0.00e+00	747.00
IUUC-Sha-107469	Sarcophilus harrisii	61.08	6.00e-122	430.00
IUUC-Ssc-115526	Sus scrofa	93.18	0.00e+00	734.00
IUUC-Tgu-117194	Taeniopygia guttata	60.31	2.00e-117	415.00
IUUC-Tru-117896	Takifugu rubripes	47.87	1.00e-100	359.00
IUUC-Tni-119943	Tetraodon nigroviridis	47.14	2.00e-89	322.00
IUUC-Ttr-128676	Tursiops truncatus	92.50	0.00e+00	752.00
IUUC-Vda-129812	Verticillium dahliae	40.26	5.00e-08	52.80
IUUC-Vpa-130319	Vicugna pacos	96.00	7.00e-57	213.00
IUUC-Xtr-132907	Xenopus tropicalis	53.81	2.00e-126	445.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence