iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ang-009600

Ensembl Protein ID

CAK45559

UniProt Accession

A2QRF8; A2QRF8_ASPNC

Genbank Protein ID

CAK45559.1

Protein Name

Aspergillus niger contig An08c0130, genomic contig

Genbank Nucleotide ID

AM270168

Gene Name

An08g05870

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
An08g05870	CAK45559	CAK45559

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/Cullin	6.30e-185	615.9	46	684

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/Cullin

   S: 25   avynlclsk.....................................vgaklYkklkevleefikqvkkkveesedeqlLktynreWekfreqlkvlrkifa 88
           av+n+c+s+                                     +g++lYk l e+l  ++ +v k+ e + +e+lL +y+reW ++++++k+++++f+
   Q: 46   AVHNFCTSQkaigssqnikahhggrsqpyrflslrnpqltpspahlLGEELYKLLGEYLSRHLDAVYKESEGHAEEALLGFYIREWLRYTTAAKYINHLFR 146
           7899999988999999999999999999999999999999999999******************************************************* PP
   S: 89   yldrtyvkk.....skkvsevrkLaldlwrkeivedikkrllelllklieaeRkgeavdrrllsgvveslveLslnk.......laiykesFEakfleatq 177
           yl+r++vk+     +k+v++v++L l +w+++++ +++++++e++l+l+e++R+ge+++++ ++++v s+v+L+l++       l++y+  FE++f +at+
   Q: 147  YLNRHWVKReidegKKNVYDVYTLHLVKWKDDFFMKVHEKVMEAVLNLVEKQRNGETIEQSQIKSIVDSFVSLGLDEsdsskstLEVYRYYFEKPFIDATR 247
           ************9999************************************************************************************* PP
   S: 178  efykaesaeflqenevdeYlkkvearlneeeeraaryleestetkLlevvekeliakhlesllaelvallrdkktedlsrmykLlsrvlngleellkeles 278
            +y++es +f++en+v eY+kk+earl ee+ r+  yl++   ++L+ ++  +l++ h e l +e++ ll+++++edl+rmy+Llsr+++gl++l+ ++e+
   Q: 248  VYYENESRQFVAENSVVEYMKKAEARLDEEKARVGLYLHPDISKHLTDTCLDVLVTAHSELLRDEFQVLLDNERQEDLARMYRLLSRIKDGLDPLRTKFEA 348
           ***************************************************************************************************** PP
   S: 279  hikeqgkaalt...aeekekdpkkyVerllelknklqklvseaFnndakFlkaldkafetfvnknsvlka..akspEllAryiDqlLrksskglteeelea 374
           h++++g+aa++   a  ++ +pk yV  ll+++ ++q+lvseaFn + +F+ +ld+a+++fvn+n++ k   +k+pEllAry D+lL+++sk ++e ele+
   Q: 349  HVRKAGLAAVEkvaADGESFEPKLYVDALLQVHTRYQSLVSEAFNGESEFVRSLDNACREFVNRNKICKSgsTKTPELLARYTDSLLKRGSKAAEESELEE 449
           ***********6655556669************************************************999***************************** PP
   S: 375  qldkvllvfkyisekdvFekyYkkhLakRLlsgksasseaEesviekLkeecgaeftskLerMfqdlkvSedlnrqFk....eekenteesesvelsvlvL 471
           +l ++++vfkyi++kdvF+k+Y k+LakRL++  s+s++aE s+i+kLke+cg+e+t+kL+rMfqd+++S+dln+ ++    +  +++   + v+   ++L
   Q: 450  MLVQIMTVFKYIEDKDVFQKFYSKMLAKRLVHVSSVSDDAETSMISKLKEACGFEYTNKLQRMFQDIQISKDLNASYRdwqeKILDDDDRRKLVDSHFQIL 550
           ******************************************************************************7755445566667889999**** PP
   S: 472  sagaWptasetekvsLPaelektiekfeefYlekhsgRkLqWqhtlgraelkaelkkg...kyelqVstfQmavLLafnnsekvsveelkkatelpeeeLr 569
            +g+Wp ++   ++  P+e+ kt e+f++fY +kh+gRkL+W+++l+++e+k+++ k+   +y++qVstfQm +LL+fn+++++s+e+++kat l +e L 
   Q: 551  GTGFWPLSAPSTDFLAPPEIVKTAERFQSFYFDKHNGRKLTWLWQLCKGEIKTNYIKNtkvPYTFQVSTFQMGILLLFNEHDTLSYEDIQKATSLAPEILD 651
           ********88888****************************************99777777**************************************** PP
   S: 570  rtlqsLvsskkqvlkkepeskeieeedlfsvNqef 604
             l+ +++ k  vl+ +pe+++ e +++fs+N +f
   Q: 652  PNLSIFLKAK--VLTINPEGSKPEPGTSFSLNYNF 684
           ********88..********************998 PP

Organism

Aspergillus niger

Protein Sequence
(Fasta)

MDVPREGHRQ RDAQVGGRCG HENCMLFSAP FLASPPGPVE LDETSAVHNF CTSQKAIGSS 60
QNIKAHHGGR SQPYRFLSLR NPQLTPSPAH LLGEELYKLL GEYLSRHLDA VYKESEGHAE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACGTTC CTAGAGAAGG GCATCGACAG CGTGATGCTC AAGTTGGAGG AAGGTGTGGA 60
CATGAAAACT GTATGCTGTT CAGCGCTCCT TTCCTGGCTT CCCCACCAGG TCCTGTCGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016158--Cullin_homology
IPR001373--Cullin_N
IPR019559--Cullin_neddylation_domain
IPR016159--Cullin_repeat-like_dom
IPR011991--WHTH_DNA-bd_dom

PROSITE

PS50069--CULLIN_2

Pfam

PF00888--Cullin
PF10557--Cullin_Nedd8

SMART

SM00182--CULLIN
SM00884--Cullin_Nedd8

Gene Ontology

GO:0005829--C:cytosol
GO:0043224--C:nuclear SCF ubiquitin ligase complex
GO:1903467--P:negative regulation of mitotic DNA replication initiation
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002277	Ailuropoda melanoleuca	48.40	0.00e+00	670.00
IUUC-Apl-003503	Anas platyrhynchos	48.71	2.00e-153	534.00
IUUC-Aca-005030	Anolis carolinensis	42.80	4.00e-142	496.00
IUUC-Ago-007977	Ashbya gossypii	33.85	5.00e-126	443.00
IUUC-Acl-008190	Aspergillus clavatus	88.09	0.00e+00	1287.00
IUUC-Afl-008542	Aspergillus flavus	82.51	0.00e+00	1140.00
IUUC-Afu-009007	Aspergillus fumigatus	88.83	0.00e+00	1296.00
IUUC-Ani-009290	Aspergillus nidulans	85.95	0.00e+00	1305.00
IUUC-Aor-009978	Aspergillus oryzae	89.01	0.00e+00	1248.00
IUUC-Ate-010584	Aspergillus terreus	89.72	0.00e+00	1306.00
IUUC-Ame-011861	Astyanax mexicanus	49.79	0.00e+00	652.00
IUUC-Bgr-012209	Blumeria graminis	66.26	0.00e+00	975.00
IUUC-Bta-012878	Bos taurus	48.40	0.00e+00	667.00
IUUC-Bci-013941	Botrytis cinerea	67.39	0.00e+00	1026.00
IUUC-Cel-018294	Caenorhabditis elegans	39.26	4.00e-153	533.00
IUUC-Cja-018965	Callithrix jacchus	49.23	0.00e+00	652.00
IUUC-Cfa-020671	Canis familiaris	48.40	0.00e+00	667.00
IUUC-Cpo-021762	Cavia porcellus	48.40	0.00e+00	667.00
IUUC-Cre-022585	Chlamydomonas reinhardtii	32.39	8.00e-93	333.00
IUUC-Csa-023873	Chlorocebus sabaeus	48.40	0.00e+00	667.00
IUUC-Cin-025547	Ciona intestinalis	45.95	9.00e-179	618.00
IUUC-Csv-026083	Ciona savignyi	46.37	0.00e+00	646.00
IUUC-Cgl-026452	Colletotrichum gloeosporioides	65.63	0.00e+00	975.00
IUUC-Cne-026919	Cryptococcus neoformans	46.45	0.00e+00	645.00
IUUC-Dre-027875	Danio rerio	50.21	0.00e+00	653.00
IUUC-Dno-028931	Dasypus novemcinctus	48.40	0.00e+00	664.00
IUUC-Dor-030846	Dipodomys ordii	51.82	5.00e-142	496.00
IUUC-Dse-031472	Dothistroma septosporum	63.87	0.00e+00	961.00
IUUC-Dme-031793	Drosophila melanogaster	42.61	5.00e-170	589.00
IUUC-Ete-033112	Echinops telfairi	44.89	8.00e-73	266.00
IUUC-Eca-034309	Equus caballus	48.40	0.00e+00	667.00
IUUC-Fca-036330	Felis catus	47.61	0.00e+00	644.00
IUUC-Fal-036899	Ficedula albicollis	48.36	4.00e-159	553.00
IUUC-Fox-037705	Fusarium oxysporum	67.29	0.00e+00	949.00
IUUC-Fso-038367	Fusarium solani	68.58	0.00e+00	986.00
IUUC-Gmo-038708	Gadus morhua	49.58	0.00e+00	653.00
IUUC-Ggr-039917	Gaeumannomyces graminis	65.50	0.00e+00	976.00
IUUC-Gga-041038	Gallus gallus	48.40	0.00e+00	667.00
IUUC-Gac-041820	Gasterosteus aculeatus	49.51	0.00e+00	672.00
IUUC-Ggo-045154	Gorilla gorilla	41.76	3.00e-132	463.00
IUUC-Hsa-046034	Homo sapiens	48.40	0.00e+00	667.00
IUUC-Itr-048285	Ictidomys tridecemlineatus	48.40	0.00e+00	667.00
IUUC-Kpa-049231	Komagataella pastoris	40.87	2.00e-148	518.00
IUUC-Lch-049673	Latimeria chalumnae	48.66	0.00e+00	660.00
IUUC-Loc-052490	Lepisosteus oculatus	48.53	0.00e+00	655.00
IUUC-Lma-053191	Leptosphaeria maculans	66.71	0.00e+00	998.00
IUUC-Laf-054582	Loxodonta africana	48.40	0.00e+00	667.00
IUUC-Mcc-055162	Macaca mulatta	47.87	0.00e+00	654.00
IUUC-Meu-055904	Macropus eugenii	46.26	5.00e-73	267.00
IUUC-Mor-057035	Magnaporthe oryzae	65.81	0.00e+00	947.00
IUUC-Mpo-057555	Magnaporthe poae	65.63	0.00e+00	980.00
IUUC-Mla-059021	Melampsora laricipopulina	53.86	0.00e+00	712.00
IUUC-Mga-060078	Meleagris gallopavo	48.40	0.00e+00	667.00
IUUC-Mvi-060519	Microbotryum violaceum	51.06	0.00e+00	718.00
IUUC-Mmr-061312	Microcebus murinus	48.40	0.00e+00	667.00
IUUC-Mdo-062867	Monodelphis domestica	48.13	0.00e+00	663.00
IUUC-Mmu-063336	Mus musculus	48.40	0.00e+00	667.00
IUUC-Mac-065061	Musa acuminata	31.83	1.00e-92	332.00
IUUC-Mpu-066400	Mustela putorius furo	48.36	5.00e-159	552.00
IUUC-Mlu-067800	Myotis lucifugus	48.80	0.00e+00	670.00
IUUC-Nfi-068384	Neosartorya fischeri	86.07	0.00e+00	1276.00
IUUC-Ncr-068965	Neurospora crassa	65.27	0.00e+00	942.00
IUUC-Nle-069729	Nomascus leucogenys	48.40	0.00e+00	667.00
IUUC-Opr-071197	Ochotona princeps	33.00	5.00e-101	360.00
IUUC-Ont-071729	Oreochromis niloticus	47.99	0.00e+00	657.00
IUUC-Oan-073309	Ornithorhynchus anatinus	48.40	0.00e+00	667.00
IUUC-Ocu-074661	Oryctolagus cuniculus	50.00	0.00e+00	660.00
IUUC-Ola-087422	Oryzias latipes	47.83	0.00e+00	670.00
IUUC-Oga-088130	Otolemur garnettii	48.40	0.00e+00	667.00
IUUC-Oar-089510	Ovis aries	48.08	0.00e+00	631.00
IUUC-Ptr-090665	Pan troglodytes	48.40	0.00e+00	667.00
IUUC-Pan-092218	Papio anubis	48.40	0.00e+00	667.00
IUUC-Psi-093175	Pelodiscus sinensis	48.40	0.00e+00	667.00
IUUC-Pma-094502	Petromyzon marinus	47.54	0.00e+00	645.00
IUUC-Pno-095067	Phaeosphaeria nodorum	67.83	0.00e+00	1030.00
IUUC-Pfo-096705	Poecilia formosa	49.72	0.00e+00	680.00
IUUC-Pab-097578	Pongo abelii	48.40	0.00e+00	667.00
IUUC-Pca-100242	Procavia capensis	51.08	2.00e-143	501.00
IUUC-Pva-102155	Pteropus vampyrus	42.40	8.00e-155	539.00
IUUC-Pgr-103297	Puccinia graminis	50.00	0.00e+00	715.00
IUUC-Ptt-103706	Puccinia triticina	48.33	4.00e-107	381.00
IUUC-Pte-104257	Pyrenophora teres	67.03	0.00e+00	1020.00
IUUC-Pyt-104795	Pyrenophora triticirepentis	67.16	0.00e+00	1021.00
IUUC-Rno-105939	Rattus norvegicus	48.40	0.00e+00	667.00
IUUC-Sce-106293	Saccharomyces cerevisiae	32.53	4.00e-120	424.00
IUUC-Sha-106949	Sarcophilus harrisii	48.40	0.00e+00	667.00
IUUC-Sja-107737	Schizosaccharomyces japonicus	46.70	2.00e-180	624.00
IUUC-Spo-108280	Schizosaccharomyces pombe	47.77	0.00e+00	632.00
IUUC-Sar-113138	Sorex araneus	36.19	2.00e-125	441.00
IUUC-Sre-114984	Sporisorium reilianum	51.42	0.00e+00	682.00
IUUC-Ssc-115829	Sus scrofa	47.94	0.00e+00	658.00
IUUC-Tgu-116950	Taeniopygia guttata	48.40	0.00e+00	667.00
IUUC-Tru-118558	Takifugu rubripes	49.65	0.00e+00	668.00
IUUC-Tsy-119621	Tarsius syrichta	38.62	9.00e-102	362.00
IUUC-Tni-120460	Tetraodon nigroviridis	49.58	0.00e+00	672.00
IUUC-Tre-122223	Trichoderma reesei	67.67	0.00e+00	927.00
IUUC-Tvi-122539	Trichoderma virens	61.59	0.00e+00	870.00
IUUC-Tme-126926	Tuber melanosporum	66.71	0.00e+00	1001.00
IUUC-Tbe-127369	Tupaia belangeri	52.27	2.00e-90	325.00
IUUC-Ttr-129022	Tursiops truncatus	48.16	3.00e-153	533.00
IUUC-Uma-129341	Ustilago maydis	51.52	0.00e+00	658.00
IUUC-Vda-129857	Verticillium dahliae	67.39	0.00e+00	934.00
IUUC-Vpa-130166	Vicugna pacos	44.44	1.00e-139	488.00
IUUC-Xtr-131818	Xenopus tropicalis	48.27	0.00e+00	661.00
IUUC-Xma-134206	Xiphophorus maculatus	49.72	0.00e+00	655.00
IUUC-Yli-134486	Yarrowia lipolytica	42.14	5.00e-159	553.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence