iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-011886

Ensembl Protein ID

ENSAMXP00000013734.1

UniProt Accession

W5L1M2; W5L1M2_ASTMX

Genbank Protein ID

ENSAMXP00000013734

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01120240

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000013347.1	ENSAMXT00000013734.1	ENSAMXP00000013734.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	8.90e-82	275.2	512	864

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           +GlkN g+tCYmN+v Q+L++ p l e +l+     ++++  ++p++++ +++q+lf +l++sk +++ p++++k++k++++e+   eq
   Q: 512  VGLKNGGATCYMNAVFQQLYMQPGLPESILS-----IEDD-AENPEESVFCQVQSLFGHLMESKLQYYVPENFWKIFKMWNKELYVREQ 594
           6******************************.....5544.46899******************************************* PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           qDa Ef++ l+dql+e+l                          kk   ++l +++Fqg +++q +c++c ++++ree+f+ l+l v +
   Q: 595  QDAYEFFTSLVDQLDEHL--------------------------KKIGREQLFKNTFQGIFSDQKICKDCPHRYEREETFMALNLGVTS 657
           ******************..........................6788999************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            +     sl+ +L++f++ e leg+n+yycekck+k++++k++ +k+lP vL++hL+Rf f+ e ++++k ++++ fp  L+++p+++s
   Q: 658  CQ-----SLEISLDQFVRGEVLEGSNAYYCEKCKEKRTTVKRTCIKSLPSVLVIHLMRFGFDWESGRSIKYDEQIRFPWVLNMEPYTVS 741
           **.....9********************************************************************************* PP
   S: 268  .........................peekqkekkkYeLiavvvHsGslssGHYvayvknekgk....WllfdDskVtevke.eevleet 326
                                    p +k++ +++YeL++vvvHsG+++ GHY++++k+++g+    W++f+D+ V+e ++ +e le  
   Q: 742  gmarqdssadhgengrggeagpggsPRKKVTISENYELVGVVVHSGQAHAGHYYSFIKDRRGSsrgrWYKFNDNVVEEFDMnDETLE-Y 829
           66666666555555555555555554444444***************************65556666************97355555.4 PP
   S: 327  g........................staYvlfYkr 337
           +                        ++aY+lfY+r
   Q: 830  EcfggeyrpkvydqsnpypdvrrryWNAYMLFYQR 864
           459******************************98 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

LKVLSSKLMP TSDDEMAKTS VKSFCENFLK AGGLSLVVNV MQRDSIPSEV DYETRQGVYS 60
ICLQLARFLL VGQTMPSILD EELNKEGLDT LSSRPFRNAG RQGGRQLSLC GTPEKSSYRQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACTGGACCA TACTGAATTC TAATTAAATA CCCCTGAACT AAACTTTCCT TCTGTTCTTC 60
TGTTGAAGGT GTTGAGCTCC AAACTGATGC CTACCTCTGA TGATGAGATG GCTAAGACCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR001394--Peptidase_C19_UCH
IPR033382--USP24
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002266	Ailuropoda melanoleuca	84.53	0.00e+00	1781.00
IUUC-Apl-003203	Anas platyrhynchos	67.58	0.00e+00	1415.00
IUUC-Aca-004396	Anolis carolinensis	83.86	0.00e+00	1770.00
IUUC-Afu-008857	Aspergillus fumigatus	32.61	1.00e-54	209.00
IUUC-Ani-009257	Aspergillus nidulans	28.86	8.00e-47	183.00
IUUC-Ang-009759	Aspergillus niger	31.19	3.00e-57	218.00
IUUC-Ate-010246	Aspergillus terreus	25.79	2.00e-48	189.00
IUUC-Bta-013381	Bos taurus	84.62	0.00e+00	1793.00
IUUC-Bci-013798	Botrytis cinerea	32.09	1.00e-49	193.00
IUUC-Cja-018955	Callithrix jacchus	84.43	0.00e+00	1790.00
IUUC-Cfa-020720	Canis familiaris	84.53	0.00e+00	1787.00
IUUC-Cpo-022430	Cavia porcellus	81.25	0.00e+00	1707.00
IUUC-Csa-024180	Chlorocebus sabaeus	84.62	0.00e+00	1790.00
IUUC-Cho-025074	Choloepus hoffmanni	80.83	0.00e+00	1167.00
IUUC-Cgl-026466	Colletotrichum gloeosporioides	30.29	2.00e-53	206.00
IUUC-Dre-027696	Danio rerio	94.17	0.00e+00	1927.00
IUUC-Dno-029307	Dasypus novemcinctus	81.06	0.00e+00	1708.00
IUUC-Dor-030889	Dipodomys ordii	81.76	0.00e+00	1713.00
IUUC-Ete-032294	Echinops telfairi	81.11	0.00e+00	1169.00
IUUC-Eca-033823	Equus caballus	76.59	0.00e+00	1584.00
IUUC-Eeu-035178	Erinaceus europaeus	80.39	0.00e+00	1169.00
IUUC-Fca-035444	Felis catus	84.53	0.00e+00	1789.00
IUUC-Fal-037555	Ficedula albicollis	84.81	0.00e+00	1783.00
IUUC-Fox-037971	Fusarium oxysporum	32.58	1.00e-53	206.00
IUUC-Fso-038108	Fusarium solani	33.15	3.00e-52	201.00
IUUC-Gmo-038587	Gadus morhua	89.58	0.00e+00	1852.00
IUUC-Gga-041231	Gallus gallus	84.15	0.00e+00	1775.00
IUUC-Gac-041584	Gasterosteus aculeatus	88.55	0.00e+00	1831.00
IUUC-Ggo-044502	Gorilla gorilla	84.62	0.00e+00	1789.00
IUUC-Hsa-045851	Homo sapiens	84.62	0.00e+00	1790.00
IUUC-Itr-048746	Ictidomys tridecemlineatus	86.81	0.00e+00	766.00
IUUC-Lch-049999	Latimeria chalumnae	78.01	0.00e+00	1593.00
IUUC-Loc-051767	Lepisosteus oculatus	92.83	0.00e+00	1941.00
IUUC-Laf-054139	Loxodonta africana	84.24	0.00e+00	1782.00
IUUC-Mcc-055217	Macaca mulatta	84.62	0.00e+00	1789.00
IUUC-Meu-056659	Macropus eugenii	76.82	0.00e+00	1583.00
IUUC-Mpo-057310	Magnaporthe poae	31.15	2.00e-49	192.00
IUUC-Mga-059267	Meleagris gallopavo	84.15	0.00e+00	1776.00
IUUC-Mmr-060971	Microcebus murinus	84.24	0.00e+00	1779.00
IUUC-Mdo-061925	Monodelphis domestica	85.00	0.00e+00	1796.00
IUUC-Mmu-064019	Mus musculus	84.24	0.00e+00	1784.00
IUUC-Mpu-066652	Mustela putorius furo	84.53	0.00e+00	1782.00
IUUC-Mlu-067518	Myotis lucifugus	84.15	0.00e+00	1783.00
IUUC-Nfi-068259	Neosartorya fischeri	32.61	7.00e-55	210.00
IUUC-Ncr-068911	Neurospora crassa	29.95	7.00e-49	190.00
IUUC-Nle-069763	Nomascus leucogenys	84.15	0.00e+00	1775.00
IUUC-Opr-071031	Ochotona princeps	78.80	0.00e+00	1634.00
IUUC-Ont-072136	Oreochromis niloticus	85.78	0.00e+00	1828.00
IUUC-Ocu-073880	Oryctolagus cuniculus	84.24	0.00e+00	1778.00
IUUC-Ola-086544	Oryzias latipes	84.16	0.00e+00	1701.00
IUUC-Oga-088695	Otolemur garnettii	83.95	0.00e+00	1778.00
IUUC-Oar-089401	Ovis aries	84.53	0.00e+00	1788.00
IUUC-Ptr-091657	Pan troglodytes	84.62	0.00e+00	1790.00
IUUC-Pan-092394	Papio anubis	84.62	0.00e+00	1789.00
IUUC-Psi-093813	Pelodiscus sinensis	84.53	0.00e+00	1786.00
IUUC-Pma-094698	Petromyzon marinus	51.64	2.00e-124	439.00
IUUC-Pfo-096811	Poecilia formosa	88.45	0.00e+00	1827.00
IUUC-Pab-097814	Pongo abelii	84.62	0.00e+00	1789.00
IUUC-Pca-101135	Procavia capensis	81.48	0.00e+00	1403.00
IUUC-Pva-102334	Pteropus vampyrus	84.34	0.00e+00	1802.00
IUUC-Pte-104235	Pyrenophora teres	30.20	8.00e-49	190.00
IUUC-Rno-105040	Rattus norvegicus	84.34	0.00e+00	1793.00
IUUC-Sha-106658	Sarcophilus harrisii	84.65	0.00e+00	1790.00
IUUC-Sar-113153	Sorex araneus	66.78	0.00e+00	787.00
IUUC-Ssc-115641	Sus scrofa	84.62	0.00e+00	1790.00
IUUC-Tgu-117467	Taeniopygia guttata	84.46	0.00e+00	1781.00
IUUC-Tru-118074	Takifugu rubripes	78.75	0.00e+00	1650.00
IUUC-Tsy-119165	Tarsius syrichta	80.79	0.00e+00	1379.00
IUUC-Tni-119923	Tetraodon nigroviridis	73.81	0.00e+00	1547.00
IUUC-Tre-122057	Trichoderma reesei	31.77	6.00e-51	197.00
IUUC-Tvi-122570	Trichoderma virens	31.74	1.00e-48	189.00
IUUC-Tbe-127910	Tupaia belangeri	84.90	0.00e+00	1264.00
IUUC-Ttr-128218	Tursiops truncatus	82.33	0.00e+00	1784.00
IUUC-Vpa-130090	Vicugna pacos	79.40	0.00e+00	755.00
IUUC-Xtr-131911	Xenopus tropicalis	79.28	0.00e+00	1285.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence