iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
WBGene00011980	T24B8.7a	T24B8.7a
WBGene00011980	T24B8.7b	T24B8.7b
WBGene00011980	T24B8.7g	T24B8.7g
WBGene00011980	T24B8.7h	T24B8.7h

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-58	199.2	1819	2232

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle..kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaee.fsgyeqqDaqEfl 96
           +G+kN g tCYmN+++Q+L+++p l + l    +     ++    +++++ll++lq++f++l   + +a+ p+ l+k ++ e  + +++ +++Da +f 
   Q: 1819 VGMKNDGGTCYMNAMIQQLVHVPGLSRELIAlqNID---PQLRWGDNTAALLCELQRVFAQLNFAQCQAIVPEGLWKEFRFEPDMpLNTKQHHDAIDFY 1914
           6***************************99933333...34444789****************99***************9999999************ PP
   S: 97   aflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs.sreepfldlslpvpgkeetkkeslqdcLesf 194
           ++lld+ ++ l                          kk + + l ++ F g+++ + +c  c +++ s +e+f+ +sl+++g++      l+++Le+f
   Q: 1915 SILLDKCDNVL--------------------------KKLELPPLFQNRFFGKYSYEKICYGCWHRYkSPDEEFNCISLALSGDN------LEEALENF 1981
           ***********..........................6788999**********************9899**************9......9******* PP
   S: 195  tkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts.......................... 267
            +++ +egen+y+cekc++k+++  ++++ +lP +++++LkRf+++  +++ +k n+ + fp e+d++p++t+                          
   Q: 1982 LAAHVMEGENAYHCEKCDEKKTTLNRTSFLELPSTMTIQLKRFTYDLVNNMIRKDNQLFRFPFEIDMTPYMTTsrhvpdehvqdlfdemlygngeadea 2080
           **********************************************************************99989999999999999999999999999 PP
   S: 268  .....................................................peekqkekkkYeLiavvvHsGslssGHYvayvkn.........ekg 304
                                                                ++ +q+++ +YeL++v+ HsG +  GHY++++k+         + +
   Q: 2081 pspphkngvaekpnlgsgsastpslesaqkkmfrrhrsstmrlsqsfantsgfDTPSQQKPLIYELVGVLAHSGIATAGHYYSFIKErreefrdspHYN 2179
           999988888888888888888888888888888888888888888888777774444555***************************665555544455 PP
   S: 305  kWllfdDskVtevkeeevleetg...................staYvlfYkrr 338
           kW +++D  V++++ ++++                       ++aYvlfY+++
   Q: 2180 KWHHINDMIVSPMSFNNIEDLWYggtftqegvfigldervrhWNAYVLFYEKK 2232
           5***************9999655999************************985 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MLRVHCKRSK EWHNCNIGCR QAAIILDKDG LESDRGDAAR SPVTPASESD SVDLDMPAGE 60
SANSPIDGDT APLNVSNNES GDEGPRKRSA SPATANQSSW GDNPAKKICT EGIDLWVQST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCATTTCAC CATTTTTTTG ACTGAAAGTA AGTTTTACGA CATTCCGAAG CCATTGTTTT 60
TATGTTAATT ACCATGAAAA TCTCATCTTA TTTCTTCATT TAACGCGCAG CCAACCCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR013763--Cyclin-like
IPR001394--Peptidase_C19_UCH
IPR015940--UBA
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50030--UBA
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00165--UBA

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cel:CELE_T24B8.7

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002266	Ailuropoda melanoleuca	28.15	2.00e-63	237.00
IUUC-Apl-003203	Anas platyrhynchos	28.16	3.00e-58	220.00
IUUC-Aca-004396	Anolis carolinensis	28.75	2.00e-64	241.00
IUUC-Ame-010925	Astyanax mexicanus	28.12	4.00e-56	213.00
IUUC-Bta-013381	Bos taurus	28.43	1.00e-63	238.00
IUUC-Cja-018955	Callithrix jacchus	27.55	1.00e-63	238.00
IUUC-Cfa-020720	Canis familiaris	28.15	2.00e-63	238.00
IUUC-Cpo-022430	Cavia porcellus	28.15	2.00e-63	237.00
IUUC-Csa-024180	Chlorocebus sabaeus	27.55	3.00e-63	236.00
IUUC-Cho-025074	Choloepus hoffmanni	26.80	2.00e-53	204.00
IUUC-Cin-025147	Ciona intestinalis	41.33	2.00e-26	111.00
IUUC-Csv-025956	Ciona savignyi	31.91	2.00e-43	171.00
IUUC-Dre-027696	Danio rerio	31.35	2.00e-49	191.00
IUUC-Dno-029307	Dasypus novemcinctus	27.57	1.00e-61	231.00
IUUC-Dor-030889	Dipodomys ordii	30.13	3.00e-63	237.00
IUUC-Dme-032160	Drosophila melanogaster	38.22	1.00e-26	115.00
IUUC-Ete-032287	Echinops telfairi	30.37	7.00e-53	202.00
IUUC-Eca-033823	Equus caballus	28.01	1.00e-63	238.00
IUUC-Eeu-035178	Erinaceus europaeus	26.89	2.00e-52	201.00
IUUC-Fca-035444	Felis catus	28.15	2.00e-63	237.00
IUUC-Fal-037555	Ficedula albicollis	28.29	2.00e-63	238.00
IUUC-Gmo-038587	Gadus morhua	30.88	9.00e-49	188.00
IUUC-Gga-041231	Gallus gallus	28.07	3.00e-63	237.00
IUUC-Gac-041970	Gasterosteus aculeatus	27.11	6.00e-52	199.00
IUUC-Ggo-044502	Gorilla gorilla	27.55	4.00e-63	236.00
IUUC-Hsa-045851	Homo sapiens	27.55	5.00e-63	236.00
IUUC-Itr-048768	Ictidomys tridecemlineatus	30.74	2.00e-53	204.00
IUUC-Lch-049999	Latimeria chalumnae	32.47	6.00e-45	176.00
IUUC-Loc-051767	Lepisosteus oculatus	30.94	2.00e-65	244.00
IUUC-Laf-054139	Loxodonta africana	28.01	4.00e-63	236.00
IUUC-Mcc-055217	Macaca mulatta	27.55	4.00e-63	236.00
IUUC-Meu-056659	Macropus eugenii	27.94	1.00e-48	188.00
IUUC-Mga-059267	Meleagris gallopavo	28.21	6.00e-64	239.00
IUUC-Mmr-060971	Microcebus murinus	27.55	3.00e-63	237.00
IUUC-Mdo-061925	Monodelphis domestica	28.43	2.00e-65	244.00
IUUC-Mmu-064019	Mus musculus	28.29	1.00e-64	241.00
IUUC-Mpu-066652	Mustela putorius furo	28.15	9.00e-64	238.00
IUUC-Mlu-067518	Myotis lucifugus	28.01	4.00e-63	236.00
IUUC-Nle-069763	Nomascus leucogenys	27.27	1.00e-60	228.00
IUUC-Opr-071031	Ochotona princeps	29.31	1.00e-42	168.00
IUUC-Ont-072119	Oreochromis niloticus	30.15	3.00e-51	197.00
IUUC-Oan-073154	Ornithorhynchus anatinus	34.30	4.00e-43	170.00
IUUC-Ocu-073880	Oryctolagus cuniculus	28.01	4.00e-63	236.00
IUUC-Ola-086350	Oryzias latipes	29.52	3.00e-42	167.00
IUUC-Oga-088695	Otolemur garnettii	27.69	4.00e-63	236.00
IUUC-Oar-089401	Ovis aries	28.43	1.00e-63	238.00
IUUC-Ptr-091657	Pan troglodytes	27.55	5.00e-63	236.00
IUUC-Pan-092394	Papio anubis	27.55	4.00e-63	236.00
IUUC-Psi-093813	Pelodiscus sinensis	28.63	5.00e-64	239.00
IUUC-Pfo-096871	Poecilia formosa	27.27	7.00e-53	202.00
IUUC-Pab-097814	Pongo abelii	27.55	4.00e-63	236.00
IUUC-Pca-101135	Procavia capensis	28.22	3.00e-64	240.00
IUUC-Pva-102334	Pteropus vampyrus	28.71	1.00e-64	241.00
IUUC-Rno-105040	Rattus norvegicus	28.15	6.00e-64	239.00
IUUC-Sha-106658	Sarcophilus harrisii	28.43	4.00e-65	243.00
IUUC-Smo-108879	Selaginella moellendorffii	27.08	5.00e-47	183.00
IUUC-Sar-113729	Sorex araneus	30.09	9.00e-50	192.00
IUUC-Ssc-115641	Sus scrofa	28.29	7.00e-63	235.00
IUUC-Tgu-117467	Taeniopygia guttata	31.90	2.00e-48	187.00
IUUC-Tru-118074	Takifugu rubripes	27.33	7.00e-45	176.00
IUUC-Tsy-119165	Tarsius syrichta	28.95	8.00e-45	176.00
IUUC-Tni-120207	Tetraodon nigroviridis	30.67	7.00e-50	192.00
IUUC-Tbe-127910	Tupaia belangeri	27.58	8.00e-61	229.00
IUUC-Ttr-128218	Tursiops truncatus	28.33	3.00e-65	243.00
IUUC-Vpa-130581	Vicugna pacos	30.74	4.00e-53	203.00
IUUC-Xtr-131911	Xenopus tropicalis	30.04	2.00e-53	202.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence