iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-036279

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02035611

Gene Name

CRBN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000026512.1	ENSFCAT00000026898.1	ENSFCAP00000025538.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/Other	96.13	0.00e+00	851.00	IUUC-Hsa-046888

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Felis catus

Protein Sequence
(Fasta)

MADERDPQDA AHDMGNHLPL LPAESEEEDE IEMEVEDQDS KEAKKPNVIN FDTSLPTSHT 60
YLGSDMEEFH GRTLHDDDSC QVIPVLPQVM MILIPGQTLP LQLFRPQEVS MVRNLIQKDR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGGACTCT CCCCCGGCTG CCCGGGCGCC GCCCTGTCCC AGCCTCCTCT GCGGGTAAAC 60
AGACATGGCC GACGAGAGGG ATCCGCAGGA CGCTGCGCAC GACATGGGCA ACCACCTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR034750--CULT
IPR003111--Lon_substr-bd
IPR015947--PUA-like_domain
IPR004910--Yippee/Mis18/Cereblon

PROSITE

PS51788--CULT
PS51787--LON_N

Pfam

PF02190--LON_substr_bdg
PF03226--Yippee-Mis18

SMART

SM00464--LON

Gene Ontology

GO:0031464--C:Cul4A-RING E3 ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0005730--C:nucleolus
GO:0046872--F:metal ion binding
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000549	Aegilops tauschii	30.46	1.00e-23	104.00
IUUC-Aml-002159	Ailuropoda melanoleuca	98.18	0.00e+00	859.00
IUUC-Atr-002820	Amborella trichopoda	38.80	4.00e-37	149.00
IUUC-Apl-003508	Anas platyrhynchos	81.69	0.00e+00	747.00
IUUC-Aca-004675	Anolis carolinensis	85.18	0.00e+00	743.00
IUUC-Aly-005404	Arabidopsis lyrata	36.84	6.00e-38	152.00
IUUC-Ath-006819	Arabidopsis thaliana	36.32	2.00e-37	150.00
IUUC-Ani-009423	Aspergillus nidulans	38.60	4.50e-02	32.70
IUUC-Ame-010773	Astyanax mexicanus	68.64	2.00e-174	605.00
IUUC-Bta-012711	Bos taurus	95.44	0.00e+00	850.00
IUUC-Bdi-014416	Brachypodium distachyon	35.53	2.00e-37	150.00
IUUC-Bol-015668	Brassica oleracea	37.24	3.00e-39	156.00
IUUC-Bra-016836	Brassica rapa	36.62	2.00e-39	156.00
IUUC-Cja-019624	Callithrix jacchus	96.36	0.00e+00	855.00
IUUC-Cpo-022319	Cavia porcellus	95.22	0.00e+00	850.00
IUUC-Csa-023791	Chlorocebus sabaeus	96.13	0.00e+00	850.00
IUUC-Cho-024850	Choloepus hoffmanni	96.53	0.00e+00	697.00
IUUC-Csv-025832	Ciona savignyi	44.06	1.00e-89	323.00
IUUC-Cgl-026484	Colletotrichum gloeosporioides	31.82	1.40e-01	30.80
IUUC-Dre-028071	Danio rerio	68.93	9.00e-177	612.00
IUUC-Dno-029431	Dasypus novemcinctus	96.36	0.00e+00	859.00
IUUC-Dor-030571	Dipodomys ordii	79.95	0.00e+00	684.00
IUUC-Dme-031920	Drosophila melanogaster	28.24	3.00e-37	149.00
IUUC-Eca-033462	Equus caballus	96.36	0.00e+00	853.00
IUUC-Fal-037498	Ficedula albicollis	80.37	0.00e+00	721.00
IUUC-Fox-037856	Fusarium oxysporum	42.86	3.00e-01	30.00
IUUC-Gmo-038734	Gadus morhua	72.85	0.00e+00	635.00
IUUC-Gga-040615	Gallus gallus	86.14	0.00e+00	756.00
IUUC-Gac-041426	Gasterosteus aculeatus	71.95	0.00e+00	638.00
IUUC-Gma-043891	Glycine max	40.45	5.00e-39	155.00
IUUC-Ggo-045108	Gorilla gorilla	95.90	0.00e+00	848.00
IUUC-Hsa-046888	Homo sapiens	96.36	0.00e+00	851.00
IUUC-Itr-047937	Ictidomys tridecemlineatus	97.50	0.00e+00	821.00
IUUC-Lch-050189	Latimeria chalumnae	76.94	2.00e-177	615.00
IUUC-Lpe-050808	Leersia perrieri	42.08	6.00e-42	165.00
IUUC-Loc-051762	Lepisosteus oculatus	78.59	0.00e+00	657.00
IUUC-Laf-053882	Loxodonta africana	97.04	0.00e+00	846.00
IUUC-Mcc-054883	Macaca mulatta	96.13	0.00e+00	850.00
IUUC-Mtr-058216	Medicago truncatula	37.79	1.00e-40	160.00
IUUC-Mdo-062260	Monodelphis domestica	87.07	0.00e+00	773.00
IUUC-Mmu-063438	Mus musculus	92.27	0.00e+00	836.00
IUUC-Mac-064610	Musa acuminata	44.50	1.00e-45	177.00
IUUC-Mpu-066362	Mustela putorius furo	98.41	0.00e+00	867.00
IUUC-Nle-069908	Nomascus leucogenys	96.13	0.00e+00	849.00
IUUC-Ont-072223	Oreochromis niloticus	74.77	0.00e+00	648.00
IUUC-Ocu-074151	Oryctolagus cuniculus	94.62	0.00e+00	812.00
IUUC-Oba-075882	Oryza barthii	40.39	6.00e-42	165.00
IUUC-Obr-076670	Oryza brachyantha	39.36	5.00e-40	158.00
IUUC-Ogl-077753	Oryza glaberrima	40.39	6.00e-42	165.00
IUUC-Ogu-078786	Oryza glumaepatula	40.39	7.00e-42	165.00
IUUC-Oin-079191	Oryza indica	40.39	6.00e-42	165.00
IUUC-Olo-080357	Oryza longistaminata	40.39	6.00e-42	165.00
IUUC-Ome-081227	Oryza meridionalis	29.76	1.00e-18	87.80
IUUC-Oni-082557	Oryza nivara	40.39	6.00e-42	165.00
IUUC-Opu-083920	Oryza punctata	39.90	5.00e-41	162.00
IUUC-Oru-085227	Oryza rufipogon	40.39	6.00e-42	165.00
IUUC-Ola-087321	Oryzias latipes	72.41	2.00e-175	608.00
IUUC-Oga-088413	Otolemur garnettii	97.49	0.00e+00	868.00
IUUC-Oar-089512	Ovis aries	94.82	0.00e+00	847.00
IUUC-Ptr-090764	Pan troglodytes	96.36	0.00e+00	851.00
IUUC-Pan-091942	Papio anubis	96.13	0.00e+00	850.00
IUUC-Psi-092985	Pelodiscus sinensis	88.44	0.00e+00	747.00
IUUC-Ppa-095670	Physcomitrella patens	36.60	2.00e-46	180.00
IUUC-Pfo-097251	Poecilia formosa	74.77	0.00e+00	644.00
IUUC-Pab-097842	Pongo abelii	95.90	0.00e+00	849.00
IUUC-Pop-099118	Populus trichocarpa	36.67	3.00e-43	169.00
IUUC-Pca-101077	Procavia capensis	84.28	0.00e+00	724.00
IUUC-Ppe-101706	Prunus persica	38.69	2.00e-41	163.00
IUUC-Pva-102245	Pteropus vampyrus	80.06	2.00e-144	504.00
IUUC-Rno-105788	Rattus norvegicus	92.50	0.00e+00	838.00
IUUC-Smo-109165	Selaginella moellendorffii	42.51	7.00e-47	181.00
IUUC-Sit-109818	Setaria italica	41.00	2.00e-42	167.00
IUUC-Sly-111062	Solanum lycopersicum	39.09	4.00e-44	172.00
IUUC-Sbi-114298	Sorghum bicolor	39.34	1.00e-43	170.00
IUUC-Ssc-115779	Sus scrofa	97.40	0.00e+00	745.00
IUUC-Tgu-117378	Taeniopygia guttata	83.45	0.00e+00	739.00
IUUC-Tru-118515	Takifugu rubripes	72.25	2.00e-175	608.00
IUUC-Tsy-119555	Tarsius syrichta	85.19	0.00e+00	751.00
IUUC-Tni-119679	Tetraodon nigroviridis	73.67	1.00e-173	602.00
IUUC-Tca-121374	Theobroma cacao	38.20	2.00e-32	134.00
IUUC-Tae-123098	Triticum aestivum	33.33	3.00e-53	202.00
IUUC-Tur-126689	Triticum urartu	29.82	6.00e-16	79.00
IUUC-Vpa-130719	Vicugna pacos	82.05	0.00e+00	722.00
IUUC-Vvi-131014	Vitis vinifera	40.88	1.00e-40	160.00
IUUC-Xtr-131811	Xenopus tropicalis	72.94	0.00e+00	642.00
IUUC-Xma-133238	Xiphophorus maculatus	75.36	0.00e+00	642.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence