iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.70e-35	118.8	265	300
UBD/Beta-Prp	1.00e-55	189.4	213	512

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 4    dsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           d v c++f  d  +l++G+ Dg+ikvW + +g +l+
   Q: 265  DAVLCMCFsRDtEMLATGAQDGKIKVWKIQSGQCLR 300
           6799*****777********************9986 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sgheae.......vtavkfspdgkilvtgseDrtikvwdlstgkcvht 89
           +ks + c  fspd+++l+tgs dg i+vw++ttgk  + l ++ ++        v +++fs+d+++l+tg++D+ ikvw +++g+c++ 
   Q: 213  QKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLkYQAQDNfmmmddaVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRR 301
           678899******************************666644444446666666*********************************** PP
   S: 90   lk.ghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl.. 175
           ++ +h++ v++lsfs++++ ++s+s d+tir+  l++g+ l+  ++gh+++vn +++ +dg +++s+s D+tv++W++kt ++  t+  
   Q: 302  FErAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLK-EFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFks 389
           *989**************************************.********************************************88 PP
   S: 176  ...tgghtdsvysls.fdsngkelvsgsldgtvklwdlqtgecvrtlnght...dnvksvrfspnderlvsgssDgsiriWdlrsgdll 257
              t g +  v+s++ + +n +++v + + +tv + ++q g++vr++   +     + + ++sp++e+++++++D +++++ + +g+l 
   Q: 390  lgsTAGTDITVNSVIlLPKNPEHFVVCNRSNTVVIMNMQ-GQIVRSFSSGKregGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLE 477
           887555777778887666666*****************5.66888888766566566678999************************** PP
   S: 258  ktlqlhnssvisvavlsfgdnvlvlgsedskvniwk 293
           +tl+ h++ vi +a+ ++ +n +++ sed+ +++wk
   Q: 478  RTLTVHEKDVIGIAH-HPHQNLIATYSEDGLLKLWK 512
           ***************.*******************8 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MSIEIESSDV IRLIMQYLKE NSLHRALATL QEETTVSLNT VDSIESFVAD INSGHWDTVL 60
QAIQSLKLPD KTLIDLYEQV VLELIELREL GAARSLLRQT DPMIMLKQTQ PERYIHLENL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGCCGCCGG AGGTGTCGCG CGGTGTTGTG CGACCGGCTG TGTGCTGAGT GGGGCCTAGA 60
CCCGGAGCGT TACCGCTATG TCGATCGAAA TCGAGTCTTC CGAGTGAGTC CTGCCGTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR006595--CTLH_C
IPR020472--G-protein_beta_WD-40_rep
IPR006594--LisH
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50897--CTLH
PS50896--LISH
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00668--CTLH
SM00667--LisH
SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000857	Aegilops tauschii	60.27	9.00e-49	185.00
IUUC-Aml-001330	Ailuropoda melanoleuca	100.00	0.00e+00	1071.00
IUUC-Atr-002570	Amborella trichopoda	66.21	0.00e+00	724.00
IUUC-Apl-003826	Anas platyrhynchos	99.19	0.00e+00	1027.00
IUUC-Aca-005183	Anolis carolinensis	99.22	0.00e+00	1064.00
IUUC-Aly-005632	Arabidopsis lyrata	64.72	0.00e+00	720.00
IUUC-Ath-007219	Arabidopsis thaliana	64.72	0.00e+00	715.00
IUUC-Ame-011374	Astyanax mexicanus	95.91	0.00e+00	1042.00
IUUC-Bta-012890	Bos taurus	100.00	0.00e+00	1071.00
IUUC-Bdi-014061	Brachypodium distachyon	65.04	0.00e+00	728.00
IUUC-Bol-016332	Brassica oleracea	65.04	0.00e+00	722.00
IUUC-Bra-017612	Brassica rapa	64.91	0.00e+00	723.00
IUUC-Cel-018238	Caenorhabditis elegans	62.04	0.00e+00	678.00
IUUC-Cja-019336	Callithrix jacchus	100.00	0.00e+00	1071.00
IUUC-Cfa-021108	Canis familiaris	99.81	0.00e+00	1070.00
IUUC-Cpo-022052	Cavia porcellus	100.00	0.00e+00	1071.00
IUUC-Cre-022595	Chlamydomonas reinhardtii	59.77	0.00e+00	658.00
IUUC-Csa-023488	Chlorocebus sabaeus	100.00	0.00e+00	1071.00
IUUC-Cho-025010	Choloepus hoffmanni	89.86	0.00e+00	944.00
IUUC-Cin-025251	Ciona intestinalis	82.10	0.00e+00	901.00
IUUC-Csv-026092	Ciona savignyi	75.66	0.00e+00	827.00
IUUC-Dre-027382	Danio rerio	95.71	0.00e+00	1034.00
IUUC-Dno-029007	Dasypus novemcinctus	99.81	0.00e+00	1071.00
IUUC-Dor-030180	Dipodomys ordii	86.51	0.00e+00	697.00
IUUC-Dme-031762	Drosophila melanogaster	77.97	0.00e+00	869.00
IUUC-Ete-032933	Echinops telfairi	99.77	0.00e+00	892.00
IUUC-Eca-033864	Equus caballus	100.00	0.00e+00	1054.00
IUUC-Eeu-034635	Erinaceus europaeus	89.36	0.00e+00	788.00
IUUC-Fca-036119	Felis catus	100.00	0.00e+00	1071.00
IUUC-Fal-037396	Ficedula albicollis	99.60	0.00e+00	1042.00
IUUC-Gmo-038962	Gadus morhua	93.37	0.00e+00	1019.00
IUUC-Gga-040134	Gallus gallus	99.61	0.00e+00	1069.00
IUUC-Gac-041630	Gasterosteus aculeatus	93.76	0.00e+00	1019.00
IUUC-Gma-043928	Glycine max	66.21	0.00e+00	734.00
IUUC-Ggo-045061	Gorilla gorilla	99.61	0.00e+00	1066.00
IUUC-Hsa-046215	Homo sapiens	100.00	0.00e+00	1071.00
IUUC-Hvu-047799	Hordeum vulgare	66.67	5.00e-148	516.00
IUUC-Itr-048826	Ictidomys tridecemlineatus	100.00	0.00e+00	1071.00
IUUC-Lch-050209	Latimeria chalumnae	92.02	0.00e+00	976.00
IUUC-Lpe-050740	Leersia perrieri	65.23	0.00e+00	726.00
IUUC-Loc-052739	Lepisosteus oculatus	88.82	0.00e+00	954.00
IUUC-Laf-053895	Loxodonta africana	99.81	0.00e+00	1067.00
IUUC-Mcc-055183	Macaca mulatta	100.00	0.00e+00	1071.00
IUUC-Mtr-057730	Medicago truncatula	65.23	0.00e+00	712.00
IUUC-Mga-059222	Meleagris gallopavo	99.52	0.00e+00	881.00
IUUC-Mmr-061749	Microcebus murinus	99.03	0.00e+00	1057.00
IUUC-Mdo-062920	Monodelphis domestica	99.61	0.00e+00	1069.00
IUUC-Mmu-063228	Mus musculus	100.00	0.00e+00	1071.00
IUUC-Mac-065084	Musa acuminata	66.41	0.00e+00	740.00
IUUC-Mpu-066162	Mustela putorius furo	100.00	0.00e+00	1071.00
IUUC-Mlu-067471	Myotis lucifugus	99.03	0.00e+00	1064.00
IUUC-Nle-070129	Nomascus leucogenys	100.00	0.00e+00	1071.00
IUUC-Opr-071176	Ochotona princeps	100.00	0.00e+00	1054.00
IUUC-Ont-071830	Oreochromis niloticus	95.13	0.00e+00	1033.00
IUUC-Oan-072778	Ornithorhynchus anatinus	99.61	0.00e+00	1070.00
IUUC-Ocu-074570	Oryctolagus cuniculus	100.00	0.00e+00	1071.00
IUUC-Oba-075507	Oryza barthii	65.23	0.00e+00	728.00
IUUC-Obr-076672	Oryza brachyantha	65.62	0.00e+00	732.00
IUUC-Ogl-077110	Oryza glaberrima	65.23	0.00e+00	728.00
IUUC-Ogu-077976	Oryza glumaepatula	65.23	0.00e+00	728.00
IUUC-Oin-079525	Oryza indica	65.23	0.00e+00	728.00
IUUC-Olo-080391	Oryza longistaminata	63.57	0.00e+00	719.00
IUUC-Oni-082778	Oryza nivara	65.23	0.00e+00	728.00
IUUC-Opu-083710	Oryza punctata	65.43	0.00e+00	729.00
IUUC-Oru-084250	Oryza rufipogon	65.23	0.00e+00	728.00
IUUC-Osa-085363	Oryza sativa	65.23	0.00e+00	728.00
IUUC-Ola-087092	Oryzias latipes	94.74	0.00e+00	1026.00
IUUC-Olu-087753	Ostreococcus lucimarinus	50.39	1.00e-140	493.00
IUUC-Oga-088278	Otolemur garnettii	91.31	0.00e+00	957.00
IUUC-Oar-089664	Ovis aries	99.42	0.00e+00	1066.00
IUUC-Ptr-090991	Pan troglodytes	100.00	0.00e+00	1071.00
IUUC-Pan-092697	Papio anubis	100.00	0.00e+00	1071.00
IUUC-Psi-093204	Pelodiscus sinensis	100.00	0.00e+00	1045.00
IUUC-Ppa-095325	Physcomitrella patens	66.02	0.00e+00	738.00
IUUC-Pfo-096988	Poecilia formosa	94.93	0.00e+00	1034.00
IUUC-Pab-098288	Pongo abelii	100.00	0.00e+00	1071.00
IUUC-Pop-098787	Populus trichocarpa	66.28	0.00e+00	739.00
IUUC-Pca-100583	Procavia capensis	93.06	0.00e+00	957.00
IUUC-Ppe-101307	Prunus persica	65.43	0.00e+00	731.00
IUUC-Pva-102711	Pteropus vampyrus	100.00	0.00e+00	1071.00
IUUC-Sha-107017	Sarcophilus harrisii	99.81	0.00e+00	1071.00
IUUC-Smo-109547	Selaginella moellendorffii	63.55	0.00e+00	677.00
IUUC-Sit-110278	Setaria italica	65.23	0.00e+00	708.00
IUUC-Sly-111777	Solanum lycopersicum	67.19	0.00e+00	740.00
IUUC-Stu-112293	Solanum tuberosum	66.99	0.00e+00	738.00
IUUC-Sar-112955	Sorex araneus	89.88	0.00e+00	947.00
IUUC-Sbi-114802	Sorghum bicolor	65.43	0.00e+00	703.00
IUUC-Ssc-116054	Sus scrofa	100.00	0.00e+00	1071.00
IUUC-Tgu-116909	Taeniopygia guttata	98.44	0.00e+00	1056.00
IUUC-Tru-118195	Takifugu rubripes	94.54	0.00e+00	1030.00
IUUC-Tsy-119420	Tarsius syrichta	92.20	0.00e+00	969.00
IUUC-Tni-120416	Tetraodon nigroviridis	94.15	0.00e+00	1024.00
IUUC-Tca-121653	Theobroma cacao	66.28	0.00e+00	712.00
IUUC-Tae-125609	Triticum aestivum	64.65	0.00e+00	725.00
IUUC-Tur-126197	Triticum urartu	66.12	3.00e-155	540.00
IUUC-Tbe-128009	Tupaia belangeri	100.00	0.00e+00	716.00
IUUC-Ttr-128719	Tursiops truncatus	91.42	0.00e+00	964.00
IUUC-Vpa-130579	Vicugna pacos	99.61	0.00e+00	1063.00
IUUC-Vvi-131127	Vitis vinifera	66.99	0.00e+00	739.00
IUUC-Xtr-132950	Xenopus tropicalis	91.88	0.00e+00	978.00
IUUC-Xma-133537	Xiphophorus maculatus	94.93	0.00e+00	1034.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence