iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-11	42.3	249	279

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 6    vtclaf.sdtllvsGsdDgtikvWDlrtgvl 35
            ++++f +++l++s+sdD+ ++ WD+rt ++
   Q: 249  AHSVRFfNNHLFASCSDDNILRFWDTRTADK 279
           5899*988899***************99876 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Present with 3750 molecules/cell in log phase SD medium.

Protein Sequence
(Fasta)

MAKSKSSQGA SGARRKPAPS LYQHISSFKP QFSTRVDDVL HFSKTLTWRS EIIPDKSKGT 60
LTTSLLYSQG SDIYEIDTTL PLKTFYDDDD DDDNDDDDEE GNGKTKSAAT PNPEYGDAFQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGAAAA GCAAATCCAG TCAGGGTGCG AGTGGAGCAC GCCGTAAACC GGCACCTTCT 60
TTATACCAAC ACATTTCTAG CTTTAAACCA CAATTCAGCA CAAGAGTCGA CGATGTTTTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0469--Meiosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0000981--F:RNA polymerase II transcription factor activity, sequence-specific DNA binding
GO:0003714--F:transcription corepressor activity
GO:0034629--P:cellular protein complex localization
GO:0006974--P:cellular response to DNA damage stimulus
GO:0061186--P:negative regulation of chromatin silencing at silent mating-type cassette
GO:0031939--P:negative regulation of chromatin silencing at telomere
GO:0010674--P:negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated

KEGG

sce:YOR229W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Lch-049627	Latimeria chalumnae	36.14	2.00e-06	45.10

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence