iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055725

Ensembl Protein ID

ENSMMUP00000024400.2

UniProt Accession

F6YN98; F6YN98_MACMU

Genbank Protein ID

AFE80720.1; AFI33508.1

Protein Name

Src kinase-associated phosphoprotein 2

Genbank Nucleotide ID

JSUE03028547; JV043437

Gene Name

SKAP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000018544.3	ENSMMUT00000026074.3	ENSMMUP00000024400.2
ENSMMUG00000018544.3	ENSMMUT00000057953.1	ENSMMUP00000055450.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-11	45.3	302	355

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
            q l+d +++ +deL++k+Gdv+++++ke +  gW++g  e +g  Gl+P+ ++ +
   Q: 302  YQGLWDCTGAFSDELSFKRGDVIYILSKEYNRYGWWVG--EMKGAIGLVPKAYIME 355
           57789999999***************************..9************987 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MPNPSSTSSP YPLPEEIRNL LADVETFVAD TLKGENLSKK AKEKRESLIK KIKDVKSVYL 60
QEFQDKGDAE DGEEYDDPFA GPPDTISLAS ERYDKDDETP SDGVQFPPIA AQDLPFVLKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTTCTGGGGC CGGGAAAACC GAGGAATACA CATGCGCAGT TGGACCCCTC AGGCCCTTCG 60
TGTCTCTTCC TACCCATCTC CCCGCCCCGA CCCTCTGGGC GGGGCCGGGC CGACAGTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0418--Kinase
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00169--PH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00233--PH
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0016301--F:kinase activity
GO:0005070--F:SH3/SH2 adaptor activity
GO:0002757--P:immune response-activating signal transduction
GO:0008285--P:negative regulation of cell proliferation

KEGG

mcc:701461

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001212	Ailuropoda melanoleuca	92.20	0.00e+00	649.00
IUUC-Apl-003565	Anas platyrhynchos	73.15	9.00e-102	362.00
IUUC-Aca-005159	Anolis carolinensis	67.69	7.00e-124	436.00
IUUC-Ame-011510	Astyanax mexicanus	60.92	3.00e-108	384.00
IUUC-Bta-013222	Bos taurus	90.81	2.00e-180	624.00
IUUC-Cja-019091	Callithrix jacchus	92.78	0.00e+00	671.00
IUUC-Cfa-020492	Canis familiaris	93.59	0.00e+00	635.00
IUUC-Cpo-021974	Cavia porcellus	89.57	9.00e-169	585.00
IUUC-Csa-023195	Chlorocebus sabaeus	99.22	9.00e-140	488.00
IUUC-Cho-024462	Choloepus hoffmanni	83.89	4.00e-172	597.00
IUUC-Dre-027975	Danio rerio	49.09	1.00e-54	206.00
IUUC-Dno-029759	Dasypus novemcinctus	93.06	0.00e+00	629.00
IUUC-Dor-030116	Dipodomys ordii	79.94	6.00e-152	530.00
IUUC-Eca-034293	Equus caballus	91.92	8.00e-178	615.00
IUUC-Fca-036423	Felis catus	91.64	0.00e+00	637.00
IUUC-Fal-037146	Ficedula albicollis	69.16	3.00e-111	394.00
IUUC-Gmo-039059	Gadus morhua	57.10	2.00e-84	305.00
IUUC-Gga-040385	Gallus gallus	70.32	1.00e-116	412.00
IUUC-Gac-042122	Gasterosteus aculeatus	57.54	2.00e-93	335.00
IUUC-Ggo-044961	Gorilla gorilla	98.61	0.00e+00	691.00
IUUC-Hsa-046197	Homo sapiens	98.33	0.00e+00	689.00
IUUC-Lch-049485	Latimeria chalumnae	72.04	3.00e-111	394.00
IUUC-Loc-052335	Lepisosteus oculatus	63.14	1.00e-109	389.00
IUUC-Laf-053622	Loxodonta africana	91.41	0.00e+00	638.00
IUUC-Meu-056098	Macropus eugenii	81.55	1.00e-158	551.00
IUUC-Mga-059932	Meleagris gallopavo	77.04	3.00e-111	394.00
IUUC-Mmr-061781	Microcebus murinus	90.25	9.00e-169	585.00
IUUC-Mdo-062502	Monodelphis domestica	76.94	1.00e-148	518.00
IUUC-Mmu-063978	Mus musculus	90.81	0.00e+00	631.00
IUUC-Mpu-065930	Mustela putorius furo	91.64	0.00e+00	646.00
IUUC-Mlu-067603	Myotis lucifugus	89.11	8.00e-116	409.00
IUUC-Nle-069223	Nomascus leucogenys	97.77	0.00e+00	685.00
IUUC-Opr-070422	Ochotona princeps	69.36	8.00e-116	409.00
IUUC-Ont-072351	Oreochromis niloticus	57.35	4.00e-104	370.00
IUUC-Oan-073125	Ornithorhynchus anatinus	89.11	3.00e-127	447.00
IUUC-Ocu-074410	Oryctolagus cuniculus	89.42	4.00e-170	590.00
IUUC-Ola-087314	Oryzias latipes	53.85	1.00e-89	323.00
IUUC-Oga-087912	Otolemur garnettii	91.36	0.00e+00	637.00
IUUC-Oar-089480	Ovis aries	91.36	0.00e+00	626.00
IUUC-Ptr-091579	Pan troglodytes	98.61	0.00e+00	692.00
IUUC-Pan-092200	Papio anubis	91.64	1.00e-178	619.00
IUUC-Psi-093510	Pelodiscus sinensis	76.08	2.00e-103	368.00
IUUC-Pfo-096925	Poecilia formosa	56.94	1.00e-98	353.00
IUUC-Pab-097723	Pongo abelii	97.21	0.00e+00	682.00
IUUC-Pca-100318	Procavia capensis	90.28	0.00e+00	641.00
IUUC-Pva-102860	Pteropus vampyrus	90.25	0.00e+00	638.00
IUUC-Rno-105825	Rattus norvegicus	86.91	2.00e-171	595.00
IUUC-Sha-107224	Sarcophilus harrisii	79.24	7.00e-133	466.00
IUUC-Sar-112982	Sorex araneus	82.14	3.00e-146	511.00
IUUC-Ssc-115926	Sus scrofa	91.09	0.00e+00	642.00
IUUC-Tgu-116935	Taeniopygia guttata	71.21	2.00e-102	364.00
IUUC-Tru-118152	Takifugu rubripes	50.85	3.00e-91	328.00
IUUC-Tsy-119643	Tarsius syrichta	85.52	2.00e-164	571.00
IUUC-Tni-120040	Tetraodon nigroviridis	56.42	1.00e-100	359.00
IUUC-Tbe-127242	Tupaia belangeri	92.76	2.00e-160	558.00
IUUC-Ttr-128482	Tursiops truncatus	82.45	1.00e-149	522.00
IUUC-Vpa-130355	Vicugna pacos	42.17	4.00e-68	251.00
IUUC-Xtr-132597	Xenopus tropicalis	57.46	3.00e-98	351.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence