iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118381

UUCD1 version

UUC-TaR-01160

Ensembl Protein ID

ENSTRUP00000034094.1

UniProt Accession

H2UAX6; H2UAX6_TAKRU

Protein Name

Uncharacterized protein

Gene Name

usp14

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000013379.1	ENSTRUT00000034220.1	ENSTRUP00000034094.1
ENSTRUG00000013379.1	ENSTRUT00000034221.1	ENSTRUP00000034095.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.60e-60	206.3	105	482
ULD/UDP/UBQ/UBQ_Other	7.90e-08	33.3	6	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl NlgNtCYmN+++QcL ++pel+ +l + ++ +l+ +  + p+  ++ +l++l e + ++++++  p  ll+ ++++ ++f     
   Q: 105  CGLANLGNTCYMNATVQCLRSVPELKTALRR-YSGALRSTGANAPSDYITAALRDLYETM-DKTSSSLPPIILLQFVHMAFPQFAekgd 191
           7****************************99.****************************.99999******************999** PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvs..sreepfl 170
             +y qqDa+E++ +++  l+++l+       e+++  + + +++e +      +k+li++ F++++++++kc e + +   + +e+ l
   Q: 192  qgQYLQQDANECWLQMMRVLQQKLEP-----LESATPMEVELTDSEGSAASACTKKNLIEQYFGVEFETTMKCTESEDEEpiKGKESQL 275
           999*********************44.....4444444444445566677778889*******************99999545566666 PP
   S: 171  dlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleL 259
           +ls+ ++++ +     l   L+   +ee  +      + + +++    k+ kl++lP +L++++ Rf ++e++ ++ k+ k v+fpl+L
   Q: 276  QLSCFINQEVK----YLATGLRLRLQEEITK-----MSATLDRNALYIKSSKLSRLPGYLTVQMVRFFYKEKEAVNAKVLKDVKFPLML 355
           66666666665....6999999999999888.....467777788889***************************************** PP
   S: 260  dlspfcts..........................peekqke.........................kkkYeLiavvvHsG.slssGHYv 296
           d+ + cts                          +     +                         +  Y+L av+ H+G s+ssGHYv
   Q: 356  DVYELCTSelqekmltirsrfkevedkklekqqqK-----VmqrpdgakevkyepfsfpddmgsnnSGYYDLQAVLTHQGrSSSSGHYV 439
           ********777777777777777777666555550.....1555555555666666666666666699********************* PP
   S: 297  ayvknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
            +vk ++++W++fdD+kV++v+ e++l+ +g    + aYvl+Y
   Q: 440  GWVKRKEDEWFKFDDDKVSVVTAEDILRLSGggdwHIAYVLLY 482
           ****************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           v vk+ + +   +++n  ++  ++K +++ ++g++p++q+ ++kG  L+dd  +++ +lk+g+t++++ +
   Q: 6    VNVKWGKEKFDAVELNTEEPPMVFKAQLFALTGVQPDRQKVMVKGGTLKDD-EWGNIKLKNGMTLLMMGS 74
           779999999889999************************************.***************976 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MPVFTVNVKW GKEKFDAVEL NTEEPPMVFK AQLFALTGVQ PDRQKVMVKG GTLKDDEWGN 60
IKLKNGMTLL MMGSAEALPE EPAVRPMFVE DMTEEQLASA MELPCGLANL GNTCYMNATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCATGCAGTG ACACAGCGTC ATTCTGTTTG AATGAAGTTC AGAAGTAGCG AACTATTTCT 60
CGTCTTGGGG CATTGAAACC AATTAGGAAT TGATTGAGTG TCAATTATGC CGGTTTTTAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	43.96	3.00e-38	153.00
IUUC-Aml-002053	Ailuropoda melanoleuca	79.55	0.00e+00	774.00
IUUC-Atr-002725	Amborella trichopoda	42.00	9.00e-98	350.00
IUUC-Apl-004031	Anas platyrhynchos	80.86	0.00e+00	800.00
IUUC-Aca-004361	Anolis carolinensis	81.14	0.00e+00	828.00
IUUC-Aly-006176	Arabidopsis lyrata	41.68	7.00e-108	384.00
IUUC-Ath-007658	Arabidopsis thaliana	41.00	3.00e-107	382.00
IUUC-Ago-007796	Ashbya gossypii	31.33	5.00e-58	218.00
IUUC-Acl-008258	Aspergillus clavatus	36.83	2.00e-63	236.00
IUUC-Afl-008732	Aspergillus flavus	34.57	3.00e-79	289.00
IUUC-Afu-008755	Aspergillus fumigatus	34.14	4.00e-77	282.00
IUUC-Ani-009148	Aspergillus nidulans	38.54	2.00e-71	263.00
IUUC-Ang-009878	Aspergillus niger	33.56	9.00e-80	291.00
IUUC-Aor-010239	Aspergillus oryzae	34.57	3.00e-79	289.00
IUUC-Ate-010243	Aspergillus terreus	37.91	3.00e-65	243.00
IUUC-Ame-011327	Astyanax mexicanus	53.85	3.00e-133	468.00
IUUC-Bgr-012231	Blumeria graminis	33.62	1.00e-76	280.00
IUUC-Bta-012553	Bos taurus	79.47	0.00e+00	789.00
IUUC-Bci-013606	Botrytis cinerea	40.26	5.00e-70	258.00
IUUC-Bdi-014567	Brachypodium distachyon	42.74	5.00e-111	394.00
IUUC-Bol-015565	Brassica oleracea	41.63	5.00e-107	381.00
IUUC-Bra-017297	Brassica rapa	40.67	4.00e-106	378.00
IUUC-Cel-018140	Caenorhabditis elegans	42.97	2.00e-105	375.00
IUUC-Cja-019516	Callithrix jacchus	78.59	0.00e+00	793.00
IUUC-Cfa-020808	Canis familiaris	79.27	0.00e+00	791.00
IUUC-Cpo-021688	Cavia porcellus	79.27	0.00e+00	782.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	37.88	3.00e-86	312.00
IUUC-Csa-023429	Chlorocebus sabaeus	79.27	0.00e+00	777.00
IUUC-Cho-024347	Choloepus hoffmanni	78.86	0.00e+00	786.00
IUUC-Cin-025198	Ciona intestinalis	52.54	7.00e-150	523.00
IUUC-Csv-026007	Ciona savignyi	53.00	6.00e-152	530.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	41.02	1.00e-66	247.00
IUUC-Cne-026963	Cryptococcus neoformans	34.46	5.00e-74	271.00
IUUC-Cme-027240	Cyanidioschyzon merolae	31.98	2.00e-64	239.00
IUUC-Dre-027647	Danio rerio	87.20	0.00e+00	885.00
IUUC-Dno-029967	Dasypus novemcinctus	79.27	0.00e+00	777.00
IUUC-Dor-030886	Dipodomys ordii	72.83	3.00e-179	621.00
IUUC-Dse-031466	Dothistroma septosporum	35.37	1.00e-55	211.00
IUUC-Dme-032079	Drosophila melanogaster	55.10	2.00e-158	551.00
IUUC-Ete-032351	Echinops telfairi	69.92	0.00e+00	697.00
IUUC-Eca-033461	Equus caballus	79.27	0.00e+00	829.00
IUUC-Eeu-035220	Erinaceus europaeus	61.44	9.00e-164	569.00
IUUC-Fca-036210	Felis catus	79.47	0.00e+00	793.00
IUUC-Fal-037528	Ficedula albicollis	80.49	0.00e+00	785.00
IUUC-Fox-037805	Fusarium oxysporum	39.64	9.00e-73	267.00
IUUC-Fso-038177	Fusarium solani	38.50	1.00e-68	254.00
IUUC-Gmo-038953	Gadus morhua	84.35	0.00e+00	816.00
IUUC-Ggr-039972	Gaeumannomyces graminis	36.23	2.00e-78	286.00
IUUC-Gga-040462	Gallus gallus	80.12	0.00e+00	797.00
IUUC-Gac-041312	Gasterosteus aculeatus	89.16	0.00e+00	877.00
IUUC-Gma-043255	Glycine max	41.43	6.00e-108	384.00
IUUC-Ggo-045458	Gorilla gorilla	66.60	0.00e+00	651.00
IUUC-Hsa-045706	Homo sapiens	79.27	0.00e+00	777.00
IUUC-Hvu-047821	Hordeum vulgare	47.20	8.00e-57	213.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	78.86	0.00e+00	808.00
IUUC-Lch-050464	Latimeria chalumnae	82.86	0.00e+00	820.00
IUUC-Lpe-051419	Leersia perrieri	41.68	2.00e-105	376.00
IUUC-Loc-052732	Lepisosteus oculatus	84.96	0.00e+00	865.00
IUUC-Lma-053177	Leptosphaeria maculans	38.56	6.00e-68	251.00
IUUC-Laf-053822	Loxodonta africana	79.47	0.00e+00	788.00
IUUC-Mcc-055893	Macaca mulatta	79.27	0.00e+00	777.00
IUUC-Meu-056307	Macropus eugenii	71.60	0.00e+00	706.00
IUUC-Mor-057171	Magnaporthe oryzae	39.41	1.00e-71	263.00
IUUC-Mpo-057415	Magnaporthe poae	36.71	2.00e-84	306.00
IUUC-Mtr-057901	Medicago truncatula	42.69	6.00e-111	394.00
IUUC-Mla-058897	Melampsora laricipopulina	38.79	2.00e-73	270.00
IUUC-Mga-060016	Meleagris gallopavo	80.86	0.00e+00	801.00
IUUC-Mvi-060562	Microbotryum violaceum	38.74	4.00e-65	242.00
IUUC-Mmr-060624	Microcebus murinus	78.66	0.00e+00	823.00
IUUC-Mdo-061809	Monodelphis domestica	80.32	0.00e+00	791.00
IUUC-Mmu-063869	Mus musculus	78.86	0.00e+00	785.00
IUUC-Mac-064876	Musa acuminata	40.28	2.00e-96	346.00
IUUC-Mpu-066480	Mustela putorius furo	79.67	0.00e+00	794.00
IUUC-Mlu-067866	Myotis lucifugus	79.27	0.00e+00	803.00
IUUC-Nfi-068393	Neosartorya fischeri	34.19	3.00e-74	272.00
IUUC-Ncr-068815	Neurospora crassa	39.34	2.00e-70	259.00
IUUC-Nle-070121	Nomascus leucogenys	77.65	2.00e-116	411.00
IUUC-Opr-070712	Ochotona princeps	63.70	6.00e-143	500.00
IUUC-Ont-071544	Oreochromis niloticus	91.67	0.00e+00	835.00
IUUC-Oan-073635	Ornithorhynchus anatinus	78.40	0.00e+00	648.00
IUUC-Ocu-074926	Oryctolagus cuniculus	79.07	0.00e+00	779.00
IUUC-Oba-075633	Oryza barthii	41.89	1.00e-106	379.00
IUUC-Obr-076423	Oryza brachyantha	43.03	1.00e-109	390.00
IUUC-Ogl-077913	Oryza glaberrima	42.22	7.00e-109	387.00
IUUC-Ogu-078435	Oryza glumaepatula	41.89	1.00e-106	379.00
IUUC-Oin-080072	Oryza indica	41.82	2.00e-106	379.00
IUUC-Olo-080535	Oryza longistaminata	38.20	2.00e-89	322.00
IUUC-Ome-081309	Oryza meridionalis	41.89	1.00e-106	379.00
IUUC-Oni-083113	Oryza nivara	41.89	1.00e-106	379.00
IUUC-Opu-083168	Oryza punctata	41.15	8.00e-102	363.00
IUUC-Oru-084253	Oryza rufipogon	41.89	1.00e-106	379.00
IUUC-Osa-085554	Oryza sativa	42.22	8.00e-109	387.00
IUUC-Ola-086998	Oryzias latipes	90.89	0.00e+00	869.00
IUUC-Olu-087818	Ostreococcus lucimarinus	35.61	2.00e-68	252.00
IUUC-Oga-088571	Otolemur garnettii	79.67	0.00e+00	794.00
IUUC-Oar-089526	Ovis aries	79.80	0.00e+00	787.00
IUUC-Ptr-091433	Pan troglodytes	79.27	0.00e+00	777.00
IUUC-Pan-091966	Papio anubis	79.27	0.00e+00	777.00
IUUC-Psi-093458	Pelodiscus sinensis	79.66	0.00e+00	770.00
IUUC-Pma-094343	Petromyzon marinus	67.70	4.00e-118	417.00
IUUC-Pno-095109	Phaeosphaeria nodorum	37.72	3.00e-64	239.00
IUUC-Ppa-095756	Physcomitrella patens	43.64	2.00e-110	392.00
IUUC-Pfo-096514	Poecilia formosa	92.48	0.00e+00	862.00
IUUC-Pab-098477	Pongo abelii	69.30	9.00e-176	609.00
IUUC-Pop-099221	Populus trichocarpa	39.88	3.00e-100	358.00
IUUC-Pca-100791	Procavia capensis	66.28	5.00e-147	513.00
IUUC-Ppe-101812	Prunus persica	40.76	5.00e-105	374.00
IUUC-Pva-102462	Pteropus vampyrus	75.64	0.00e+00	639.00
IUUC-Pgr-103623	Puccinia graminis	39.32	5.00e-74	271.00
IUUC-Ptt-103767	Puccinia triticina	37.09	1.00e-65	244.00
IUUC-Pte-104109	Pyrenophora teres	35.69	8.00e-85	308.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	39.39	2.00e-68	253.00
IUUC-Rno-105351	Rattus norvegicus	79.27	0.00e+00	769.00
IUUC-Sce-106168	Saccharomyces cerevisiae	31.47	4.00e-61	229.00
IUUC-Sha-107491	Sarcophilus harrisii	81.38	0.00e+00	805.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	34.52	5.00e-81	294.00
IUUC-Spo-108174	Schizosaccharomyces pombe	37.85	1.00e-80	293.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	34.78	7.00e-84	304.00
IUUC-Smo-108805	Selaginella moellendorffii	43.24	1.00e-110	393.00
IUUC-Sit-110361	Setaria italica	42.03	3.00e-111	395.00
IUUC-Sly-110965	Solanum lycopersicum	40.04	2.00e-105	375.00
IUUC-Sar-113355	Sorex araneus	68.15	2.00e-155	541.00
IUUC-Sbi-114778	Sorghum bicolor	42.45	2.00e-109	389.00
IUUC-Sre-115011	Sporisorium reilianum	36.97	1.00e-61	230.00
IUUC-Ssc-116273	Sus scrofa	78.98	0.00e+00	775.00
IUUC-Tgu-117063	Taeniopygia guttata	80.78	0.00e+00	783.00
IUUC-Tsy-119076	Tarsius syrichta	66.27	2.00e-95	342.00
IUUC-Tni-119941	Tetraodon nigroviridis	95.73	0.00e+00	912.00
IUUC-Tca-121246	Theobroma cacao	41.62	3.00e-107	382.00
IUUC-Tre-121969	Trichoderma reesei	37.87	1.00e-69	257.00
IUUC-Tvi-122543	Trichoderma virens	34.92	1.00e-82	300.00
IUUC-Tae-125484	Triticum aestivum	41.77	2.00e-108	385.00
IUUC-Tur-126128	Triticum urartu	41.38	5.00e-39	155.00
IUUC-Tbe-128030	Tupaia belangeri	72.84	0.00e+00	694.00
IUUC-Ttr-128701	Tursiops truncatus	78.49	0.00e+00	644.00
IUUC-Uma-129657	Ustilago maydis	36.13	3.00e-64	239.00
IUUC-Vda-129723	Verticillium dahliae	35.92	9.00e-60	224.00
IUUC-Vpa-130284	Vicugna pacos	56.79	2.00e-147	515.00
IUUC-Vvi-131037	Vitis vinifera	43.40	1.00e-108	387.00
IUUC-Xtr-132235	Xenopus tropicalis	78.34	0.00e+00	817.00
IUUC-Xma-133840	Xiphophorus maculatus	92.48	0.00e+00	887.00
IUUC-Yli-134453	Yarrowia lipolytica	37.62	6.00e-87	314.00
IUUC-Zma-135669	Zea mays	35.91	3.00e-92	332.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence