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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018649
Ensembl Protein ID T16H12.4.1
UniProt Accession P34567; TF2H2_CAEEL
Genbank Protein ID CAA83139.3
Protein Name General transcription factor IIH subunit 2; TFIIH basal transcription factor complex subunit 2
Genbank Nucleotide ID Z30662
Gene Name T16H12.4
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00011814 T16H12.4.1 T16H12.4.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNAmiRNAMap
Protein-protein Interaction
IIDPINA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/RING/RING 33.42 7.00e-60 225.00 IUUC-Sce-106434
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
 Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
Protein Sequence
(Fasta)
MDDDEQKGYT WEAGYAEGLN INDVLVEDEG GSIEKSIAKY VADSKRKARL TKRPERIRLG 60
IMRHVMIVID CSRFMTSKAM PPSRFVVVMK ALQTFLDRFF EQNPIAQIGL ITCKDRKADR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018649|E3,RING|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATTACTAGGT TTCAGATAAA TATGGATGAT GATGAGCAGA AGGGTTACAC CTGGGAAGCA 60
GGATATGCAG AAGGTTTGGA AATTTAATTT TAACAATATT TTCAGAAAAT GTCTAAAAAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018649|E3,RING|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR007198--Ssl1-like
IPR004595--TFIIH_C1-like_dom
IPR012170--TFIIH_SSL1/p44
IPR002035--VWF_A
IPR013087--Znf_C2H2_type
IPR000433--Znf_ZZ
PROSITE

PS50234--VWFA
PS01357--ZF_ZZ_1
Pfam

PF07975--C1_4
PF04056--Ssl1
SMART

SM01047--C1_4
SM00327--VWA
Gene Ontology

GO:0000439--C:core TFIIH complex
GO:0005675--C:holo TFIIH complex
GO:0003676--F:nucleic acid binding
GO:0008270--F:zinc ion binding
GO:0006289--P:nucleotide-excision repair
GO:0006357--P:regulation of transcription from RNA polymerase II promoter
GO:0006351--P:transcription, DNA-templated
KEGG cel:CELE_T16H12.4
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000536 Aegilops tauschii 36.60 1.00e-42 165.00
IUUC-Aml-002041 Ailuropoda melanoleuca 42.16 3.00e-82 297.00
IUUC-Atr-003056 Amborella trichopoda 39.49 6.00e-62 229.00
IUUC-Apl-003464 Anas platyrhynchos 40.69 2.00e-70 257.00
IUUC-Aca-004745 Anolis carolinensis 40.53 1.00e-74 271.00
IUUC-Aly-005559 Arabidopsis lyrata 40.65 4.00e-67 247.00
IUUC-Ath-007556 Arabidopsis thaliana 40.65 4.00e-67 247.00
IUUC-Ago-007851 Ashbya gossypii 32.65 4.00e-62 230.00
IUUC-Acl-008100 Aspergillus clavatus 33.33 4.00e-57 214.00
IUUC-Afl-008649 Aspergillus flavus 35.94 2.00e-07 45.40
IUUC-Afu-009066 Aspergillus fumigatus 31.84 2.00e-58 218.00
IUUC-Ani-009372 Aspergillus nidulans 34.11 1.00e-58 218.00
IUUC-Ang-009726 Aspergillus niger 33.58 5.00e-62 230.00
IUUC-Aor-010135 Aspergillus oryzae 32.34 2.00e-58 218.00
IUUC-Ate-010399 Aspergillus terreus 31.41 9.00e-15 72.00
IUUC-Ame-011618 Astyanax mexicanus 41.28 1.00e-86 311.00
IUUC-Bgr-012154 Blumeria graminis 32.74 6.00e-59 219.00
IUUC-Bta-012353 Bos taurus 42.16 4.00e-85 306.00
IUUC-Bci-013932 Botrytis cinerea 34.97 3.00e-62 231.00
IUUC-Bdi-014391 Brachypodium distachyon 39.27 2.00e-66 244.00
IUUC-Bol-015128 Brassica oleracea 38.76 1.00e-67 249.00
IUUC-Bra-017932 Brassica rapa 38.76 9.00e-68 249.00
IUUC-Cja-018776 Callithrix jacchus 42.67 1.00e-81 295.00
IUUC-Cfa-020584 Canis familiaris 42.16 2.00e-81 295.00
IUUC-Cpo-021300 Cavia porcellus 42.67 5.00e-82 296.00
IUUC-Cre-022657 Chlamydomonas reinhardtii 32.79 5.00e-52 196.00
IUUC-Csa-024092 Chlorocebus sabaeus 42.93 6.00e-82 296.00
IUUC-Cho-024919 Choloepus hoffmanni 43.01 4.00e-37 146.00
IUUC-Cin-025386 Ciona intestinalis 38.60 1.00e-77 281.00
IUUC-Csv-026295 Ciona savignyi 37.92 9.00e-79 285.00
IUUC-Cgl-026612 Colletotrichum gloeosporioides 31.51 4.00e-51 194.00
IUUC-Cne-026956 Cryptococcus neoformans 30.70 7.00e-59 219.00
IUUC-Cme-027150 Cyanidioschyzon merolae 29.05 3.00e-38 152.00
IUUC-Dre-027962 Danio rerio 41.13 7.00e-88 315.00
IUUC-Dno-029979 Dasypus novemcinctus 43.40 3.00e-70 257.00
IUUC-Dse-031405 Dothistroma septosporum 34.23 2.00e-58 218.00
IUUC-Dme-031710 Drosophila melanogaster 37.16 2.00e-74 271.00
IUUC-Ete-032631 Echinops telfairi 39.49 1.00e-74 271.00
IUUC-Eca-034054 Equus caballus 41.13 5.00e-81 293.00
IUUC-Fca-035724 Felis catus 40.36 3.00e-76 277.00
IUUC-Fal-036987 Ficedula albicollis 40.10 2.00e-86 311.00
IUUC-Fox-037692 Fusarium oxysporum 33.33 2.00e-59 222.00
IUUC-Fso-038442 Fusarium solani 32.03 1.00e-54 205.00
IUUC-Gmo-039273 Gadus morhua 42.05 2.00e-87 315.00
IUUC-Ggr-040009 Gaeumannomyces graminis 34.14 1.00e-48 186.00
IUUC-Gga-041089 Gallus gallus 40.10 9.00e-85 305.00
IUUC-Gac-041978 Gasterosteus aculeatus 42.31 3.00e-85 307.00
IUUC-Gma-043371 Glycine max 39.64 2.00e-72 264.00
IUUC-Hsa-046001 Homo sapiens 42.93 8.00e-82 296.00
IUUC-Itr-048355 Ictidomys tridecemlineatus 43.19 9.00e-89 318.00
IUUC-Kpa-049235 Komagataella pastoris 31.84 1.00e-52 199.00
IUUC-Lch-049926 Latimeria chalumnae 41.65 1.00e-84 305.00
IUUC-Lpe-051352 Leersia perrieri 36.43 5.00e-61 226.00
IUUC-Loc-051987 Lepisosteus oculatus 41.13 3.00e-88 317.00
IUUC-Lma-053171 Leptosphaeria maculans 30.83 7.00e-47 180.00
IUUC-Laf-054372 Loxodonta africana 42.67 9.00e-85 305.00
IUUC-Mcc-055108 Macaca mulatta 42.93 6.00e-82 296.00
IUUC-Mor-056990 Magnaporthe oryzae 30.21 2.00e-53 202.00
IUUC-Mtr-058401 Medicago truncatula 37.69 2.00e-71 261.00
IUUC-Mla-059186 Melampsora laricipopulina 33.74 8.00e-65 239.00
IUUC-Mvi-060262 Microbotryum violaceum 33.58 2.00e-63 235.00
IUUC-Mmr-061688 Microcebus murinus 40.00 9.00e-71 259.00
IUUC-Mdo-062154 Monodelphis domestica 42.16 1.00e-85 308.00
IUUC-Mmu-064232 Mus musculus 42.82 8.00e-82 295.00
IUUC-Mac-065091 Musa acuminata 38.69 4.00e-68 250.00
IUUC-Mpu-066747 Mustela putorius furo 39.33 1.00e-68 252.00
IUUC-Mlu-067799 Myotis lucifugus 39.54 7.00e-71 259.00
IUUC-Nfi-068371 Neosartorya fischeri 35.44 2.00e-10 56.60
IUUC-Ncr-068704 Neurospora crassa 34.13 3.00e-58 217.00
IUUC-Nle-069054 Nomascus leucogenys 42.93 1.00e-81 295.00
IUUC-Ont-071624 Oreochromis niloticus 42.42 3.00e-89 320.00
IUUC-Oan-072898 Ornithorhynchus anatinus 41.13 1.00e-83 302.00
IUUC-Ocu-074289 Oryctolagus cuniculus 40.71 1.00e-65 241.00
IUUC-Oba-075985 Oryza barthii 35.92 3.00e-60 224.00
IUUC-Obr-076887 Oryza brachyantha 37.98 7.00e-64 236.00
IUUC-Ogl-077823 Oryza glaberrima 35.92 3.00e-60 224.00
IUUC-Ogu-078412 Oryza glumaepatula 37.54 2.00e-52 198.00
IUUC-Oin-079569 Oryza indica 36.84 3.00e-40 158.00
IUUC-Olo-080249 Oryza longistaminata 36.71 2.00e-40 159.00
IUUC-Ome-081240 Oryza meridionalis 37.54 4.00e-52 197.00
IUUC-Oni-082152 Oryza nivara 37.54 2.00e-52 198.00
IUUC-Opu-084011 Oryza punctata 36.18 1.00e-60 226.00
IUUC-Oru-084719 Oryza rufipogon 36.44 1.00e-52 199.00
IUUC-Osa-085286 Oryza sativa 35.92 3.00e-60 224.00
IUUC-Ola-086525 Oryzias latipes 38.54 6.00e-73 266.00
IUUC-Olu-087876 Ostreococcus lucimarinus 33.64 2.00e-50 191.00
IUUC-Oga-088125 Otolemur garnettii 41.39 3.00e-83 300.00
IUUC-Oar-089701 Ovis aries 42.42 2.00e-85 308.00
IUUC-Ptr-091218 Pan troglodytes 42.93 5.00e-82 296.00
IUUC-Pan-091755 Papio anubis 42.93 6.00e-82 296.00
IUUC-Psi-094061 Pelodiscus sinensis 41.39 4.00e-85 306.00
IUUC-Pma-094430 Petromyzon marinus 38.91 2.00e-53 201.00
IUUC-Pno-094900 Phaeosphaeria nodorum 28.50 3.00e-19 89.40
IUUC-Ppa-095895 Physcomitrella patens 36.86 2.00e-70 258.00
IUUC-Pfo-096297 Poecilia formosa 41.63 4.00e-61 226.00
IUUC-Pab-097717 Pongo abelii 42.93 6.00e-82 296.00
IUUC-Pop-098938 Populus trichocarpa 39.28 2.00e-69 254.00
IUUC-Pca-100389 Procavia capensis 38.78 2.00e-63 234.00
IUUC-Ppe-102045 Prunus persica 38.90 2.00e-66 245.00
IUUC-Pva-102357 Pteropus vampyrus 44.95 3.00e-33 133.00
IUUC-Pgr-103399 Puccinia graminis 34.38 4.00e-69 253.00
IUUC-Ptt-103872 Puccinia triticina 34.22 9.00e-69 253.00
IUUC-Pte-104092 Pyrenophora teres 33.45 1.00e-44 172.00
IUUC-Pyt-104669 Pyrenophora triticirepentis 33.45 9.00e-45 172.00
IUUC-Rno-105515 Rattus norvegicus 42.31 2.00e-84 304.00
IUUC-Sce-106434 Saccharomyces cerevisiae 33.42 2.00e-65 241.00
IUUC-Sha-106808 Sarcophilus harrisii 41.65 5.00e-85 306.00
IUUC-Sja-107995 Schizosaccharomyces japonicus 34.52 2.00e-57 214.00
IUUC-Spo-108044 Schizosaccharomyces pombe 35.95 5.00e-67 246.00
IUUC-Smo-109581 Selaginella moellendorffii 36.20 3.00e-67 247.00
IUUC-Sit-110704 Setaria italica 38.44 1.00e-65 242.00
IUUC-Sly-110990 Solanum lycopersicum 40.84 2.00e-58 218.00
IUUC-Stu-112542 Solanum tuberosum 40.91 8.00e-37 145.00
IUUC-Sar-113766 Sorex araneus 41.59 5.00e-68 249.00
IUUC-Sbi-114016 Sorghum bicolor 39.06 2.00e-65 241.00
IUUC-Sre-115099 Sporisorium reilianum 32.40 2.00e-62 232.00
IUUC-Ssc-115277 Sus scrofa 42.42 1.00e-79 288.00
IUUC-Tgu-117343 Taeniopygia guttata 40.21 1.00e-86 311.00
IUUC-Tru-118397 Takifugu rubripes 41.39 3.00e-85 306.00
IUUC-Tni-120272 Tetraodon nigroviridis 40.66 1.00e-84 305.00
IUUC-Tca-121514 Theobroma cacao 39.23 7.00e-71 259.00
IUUC-Tre-121990 Trichoderma reesei 32.27 7.00e-55 206.00
IUUC-Tvi-122504 Trichoderma virens 33.69 2.00e-55 208.00
IUUC-Tae-123153 Triticum aestivum 38.48 3.00e-65 241.00
IUUC-Tur-126693 Triticum urartu 41.60 2.00e-53 201.00
IUUC-Tme-127011 Tuber melanosporum 35.06 5.00e-60 223.00
IUUC-Tbe-127939 Tupaia belangeri 42.93 5.00e-82 296.00
IUUC-Ttr-128889 Tursiops truncatus 38.82 5.00e-75 273.00
IUUC-Uma-129450 Ustilago maydis 32.10 1.00e-63 236.00
IUUC-Vda-129919 Verticillium dahliae 32.78 7.00e-47 180.00
IUUC-Vvi-130928 Vitis vinifera 39.12 4.00e-68 250.00
IUUC-Xtr-131891 Xenopus tropicalis 38.04 6.00e-75 273.00
IUUC-Xma-133260 Xiphophorus maculatus 41.63 4.00e-61 226.00
IUUC-Yli-134578 Yarrowia lipolytica 31.65 2.00e-54 205.00
IUUC-Zma-135427 Zea mays 38.70 1.00e-64 239.00
Created Date 25-Jun-2017

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