iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Dre-028401

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 17

Genbank Nucleotide ID

AL845437

Gene Name

klhl17

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000037324.7	ENSDART00000137353.2	ENSDARP00000119330.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	9.80e-22	78.0	41	105
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.00e-13	48.8	140	170

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +D++l+v+++e++ahk+vLa++S++F+a+f++e++es+ +  v+++d++p+++++l+++ Yt ++ 
   Q: 41   CDIVLHVANKEIKAHKVVLASCSPYFHAMFTNEMSESR-QTHVTLHDIDPQALEQLVQYAYTAEIV 105
           8*************************************.***********************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi+ fAd+++c+dL ++a++++l+hF
   Q: 140  PSNCLGIRGFADTHSCSDLLKSAHKYVLQHF 170
           89***************************** PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MMEGGMQLLN RDGHSISHNS KRHYHDSFVS MNRMRQRGLL CDIVLHVANK EIKAHKVVLA 60
SCSPYFHAMF TNEMSESRQT HVTLHDIDPQ ALEQLVQYAY TAEIVVGEGN VQTLLPAASL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCAGAGCT GAGACAGTCG TCTGTTTTGA TGCGACATGT GATGTAGCAT GTCAACTCAT 60
CACGAACGGC TTAATAAATC ACCACATGCA TCAGAATTAA TCACAAAACA CGGACAAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0032839--C:dendrite cytoplasm
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0007420--P:brain development
GO:0016567--P:protein ubiquitination

KEGG

dre:336187

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002095	Ailuropoda melanoleuca	90.43	0.00e+00	1060.00
IUUC-Apl-003315	Anas platyrhynchos	84.73	0.00e+00	973.00
IUUC-Aca-005317	Anolis carolinensis	96.00	0.00e+00	1110.00
IUUC-Ame-010707	Astyanax mexicanus	99.83	0.00e+00	1149.00
IUUC-Bta-012531	Bos taurus	90.09	0.00e+00	1056.00
IUUC-Bra-017070	Brassica rapa	29.85	3.00e-17	83.20
IUUC-Cfa-021138	Canis familiaris	90.43	0.00e+00	1060.00
IUUC-Cpo-021432	Cavia porcellus	90.61	0.00e+00	1104.00
IUUC-Csa-023772	Chlorocebus sabaeus	89.91	0.00e+00	1080.00
IUUC-Dno-029729	Dasypus novemcinctus	88.70	0.00e+00	1037.00
IUUC-Dor-030659	Dipodomys ordii	90.09	0.00e+00	1055.00
IUUC-Dme-031996	Drosophila melanogaster	56.35	0.00e+00	648.00
IUUC-Ete-033128	Echinops telfairi	85.99	0.00e+00	820.00
IUUC-Eca-033856	Equus caballus	89.22	0.00e+00	1036.00
IUUC-Eeu-034646	Erinaceus europaeus	85.22	0.00e+00	956.00
IUUC-Fca-036183	Felis catus	90.09	0.00e+00	1054.00
IUUC-Fal-037046	Ficedula albicollis	83.69	0.00e+00	886.00
IUUC-Gmo-039526	Gadus morhua	90.16	0.00e+00	1027.00
IUUC-Gga-040510	Gallus gallus	96.35	0.00e+00	1113.00
IUUC-Gac-042529	Gasterosteus aculeatus	96.56	0.00e+00	1120.00
IUUC-Ggo-044992	Gorilla gorilla	89.74	0.00e+00	1099.00
IUUC-Hsa-046621	Homo sapiens	89.74	0.00e+00	1099.00
IUUC-Itr-048791	Ictidomys tridecemlineatus	90.61	0.00e+00	1061.00
IUUC-Lch-049449	Latimeria chalumnae	97.05	0.00e+00	1126.00
IUUC-Loc-052690	Lepisosteus oculatus	93.16	0.00e+00	1108.00
IUUC-Laf-053925	Loxodonta africana	90.29	0.00e+00	663.00
IUUC-Mcc-054780	Macaca mulatta	82.78	0.00e+00	992.00
IUUC-Meu-056812	Macropus eugenii	82.34	0.00e+00	804.00
IUUC-Mga-059704	Meleagris gallopavo	96.35	0.00e+00	1113.00
IUUC-Mmr-061724	Microcebus murinus	89.91	0.00e+00	1055.00
IUUC-Mmu-063886	Mus musculus	90.26	0.00e+00	1058.00
IUUC-Mpu-066774	Mustela putorius furo	90.09	0.00e+00	1057.00
IUUC-Nle-070159	Nomascus leucogenys	89.74	0.00e+00	1098.00
IUUC-Opr-070367	Ochotona princeps	84.09	0.00e+00	777.00
IUUC-Ont-071757	Oreochromis niloticus	98.09	0.00e+00	1131.00
IUUC-Ocu-074674	Oryctolagus cuniculus	84.39	0.00e+00	973.00
IUUC-Opu-083716	Oryza punctata	33.65	4.00e-31	130.00
IUUC-Ola-086760	Oryzias latipes	97.40	0.00e+00	1125.00
IUUC-Oga-088570	Otolemur garnettii	89.74	0.00e+00	1055.00
IUUC-Oar-090344	Ovis aries	81.03	0.00e+00	917.00
IUUC-Ptr-090946	Pan troglodytes	89.91	0.00e+00	1101.00
IUUC-Pan-092661	Papio anubis	89.91	0.00e+00	1080.00
IUUC-Psi-094009	Pelodiscus sinensis	93.60	0.00e+00	1080.00
IUUC-Ppa-095453	Physcomitrella patens	28.40	2.00e-16	80.90
IUUC-Pfo-097164	Poecilia formosa	93.86	0.00e+00	1119.00
IUUC-Pab-097554	Pongo abelii	72.54	0.00e+00	712.00
IUUC-Pca-100460	Procavia capensis	80.52	0.00e+00	957.00
IUUC-Pva-102180	Pteropus vampyrus	90.09	0.00e+00	1055.00
IUUC-Rno-105907	Rattus norvegicus	90.26	0.00e+00	1058.00
IUUC-Sar-113112	Sorex araneus	76.92	2.00e-169	588.00
IUUC-Ssc-115448	Sus scrofa	82.82	0.00e+00	777.00
IUUC-Tgu-117293	Taeniopygia guttata	95.32	0.00e+00	1103.00
IUUC-Tru-117814	Takifugu rubripes	95.66	0.00e+00	1105.00
IUUC-Tni-120531	Tetraodon nigroviridis	98.09	0.00e+00	1131.00
IUUC-Tae-124075	Triticum aestivum	32.80	7.00e-40	159.00
IUUC-Tbe-127460	Tupaia belangeri	90.91	0.00e+00	1014.00
IUUC-Xtr-132356	Xenopus tropicalis	95.65	0.00e+00	1104.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence