iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Xtr-132356

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Kelch-like family member 17

Genbank Nucleotide ID

AAMC01057324

Gene Name

klhl17

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000020253.3	ENSXETT00000043706.3	ENSXETP00000043706.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.20e-20	73.8	40	104
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.00e-13	48.7	139	169

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkld 66
           +D++l+vg +e++ hk+vLa++S++F+a+f++e++es+ +  v+++d++p+++++l+++ Yt ++ 
   Q: 40   CDIVLHVGTKEIKGHKVVLASCSPYFHAMFTNEMSESR-QTHVTLHDIDPQALEQLVQYAYTAEIV 104
           8*************************************.***********************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Nclgi+ fAd+++c+dL ++a++++l+hF
   Q: 139  PSNCLGIRGFADTHSCSDLLKSAHKYVLQHF 169
           89***************************** PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

MEGAVQLLTR DGHSISHNSK RHYHDAFVCM NRMRQRGLLC DIVLHVGTKE IKGHKVVLAS 60
CSPYFHAMFT NEMSESRQTH VTLHDIDPQA LEQLVQYAYT AEIVVGEGNV QTLLPAASLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAAGGAG CAGTGCAACT TCTCACTCGG GATGGCCATA GCATATCCCA CAATTCCAAG 60
AGGCACTACC ATGATGCCTT TGTGTGCATG AATAGGATGC GCCAGCGTGG ACTTTTGTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR011043--Gal_Oxase/kelch_b-propeller
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0032839--C:dendrite cytoplasm
GO:0051015--F:actin filament binding
GO:0030036--P:actin cytoskeleton organization
GO:0007420--P:brain development
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002095	Ailuropoda melanoleuca	91.48	0.00e+00	1070.00
IUUC-Apl-003315	Anas platyrhynchos	86.41	0.00e+00	991.00
IUUC-Aca-005317	Anolis carolinensis	97.04	0.00e+00	1122.00
IUUC-Ame-010707	Astyanax mexicanus	95.65	0.00e+00	1103.00
IUUC-Bta-012531	Bos taurus	91.13	0.00e+00	1066.00
IUUC-Bra-017070	Brassica rapa	29.35	2.00e-16	80.10
IUUC-Cfa-021138	Canis familiaris	91.48	0.00e+00	1069.00
IUUC-Cpo-021432	Cavia porcellus	92.00	0.00e+00	1116.00
IUUC-Csa-023772	Chlorocebus sabaeus	91.13	0.00e+00	1088.00
IUUC-Dre-028401	Danio rerio	95.65	0.00e+00	1104.00
IUUC-Dno-029729	Dasypus novemcinctus	89.22	0.00e+00	1042.00
IUUC-Dor-030659	Dipodomys ordii	90.96	0.00e+00	1063.00
IUUC-Dme-031996	Drosophila melanogaster	56.35	0.00e+00	650.00
IUUC-Ete-033128	Echinops telfairi	87.28	0.00e+00	831.00
IUUC-Eca-033856	Equus caballus	90.61	0.00e+00	1048.00
IUUC-Eeu-034646	Erinaceus europaeus	86.43	0.00e+00	967.00
IUUC-Fca-036183	Felis catus	91.13	0.00e+00	1063.00
IUUC-Fal-037046	Ficedula albicollis	85.31	0.00e+00	900.00
IUUC-Gmo-039526	Gadus morhua	88.26	0.00e+00	1008.00
IUUC-Gga-040510	Gallus gallus	98.09	0.00e+00	1131.00
IUUC-Gac-042529	Gasterosteus aculeatus	94.15	0.00e+00	1086.00
IUUC-Ggo-044992	Gorilla gorilla	91.30	0.00e+00	1114.00
IUUC-Hsa-046621	Homo sapiens	91.30	0.00e+00	1114.00
IUUC-Itr-048791	Ictidomys tridecemlineatus	91.65	0.00e+00	1070.00
IUUC-Lch-049449	Latimeria chalumnae	96.17	0.00e+00	1109.00
IUUC-Loc-052690	Lepisosteus oculatus	92.14	0.00e+00	1094.00
IUUC-Laf-053925	Loxodonta africana	91.43	0.00e+00	671.00
IUUC-Mcc-054780	Macaca mulatta	84.35	0.00e+00	1001.00
IUUC-Meu-056812	Macropus eugenii	83.13	0.00e+00	806.00
IUUC-Mga-059704	Meleagris gallopavo	98.09	0.00e+00	1133.00
IUUC-Mmr-061724	Microcebus murinus	91.48	0.00e+00	1070.00
IUUC-Mmu-063886	Mus musculus	91.48	0.00e+00	1068.00
IUUC-Mpu-066774	Mustela putorius furo	91.48	0.00e+00	1070.00
IUUC-Nle-070159	Nomascus leucogenys	91.30	0.00e+00	1112.00
IUUC-Opr-070367	Ochotona princeps	85.16	0.00e+00	783.00
IUUC-Ont-071757	Oreochromis niloticus	94.96	0.00e+00	1097.00
IUUC-Ocu-074674	Oryctolagus cuniculus	85.09	0.00e+00	980.00
IUUC-Obr-076712	Oryza brachyantha	35.45	2.00e-31	130.00
IUUC-Oin-080100	Oryza indica	35.00	3.00e-32	133.00
IUUC-Opu-083716	Oryza punctata	34.55	8.00e-32	132.00
IUUC-Ola-086760	Oryzias latipes	94.43	0.00e+00	1089.00
IUUC-Oga-088570	Otolemur garnettii	91.13	0.00e+00	1067.00
IUUC-Oar-090344	Ovis aries	82.22	0.00e+00	928.00
IUUC-Ptr-090946	Pan troglodytes	91.13	0.00e+00	1112.00
IUUC-Pan-092661	Papio anubis	91.13	0.00e+00	1088.00
IUUC-Psi-094009	Pelodiscus sinensis	95.49	0.00e+00	1099.00
IUUC-Ppa-095453	Physcomitrella patens	28.80	5.00e-17	82.40
IUUC-Pfo-097164	Poecilia formosa	90.70	0.00e+00	1080.00
IUUC-Pab-097554	Pongo abelii	64.17	0.00e+00	712.00
IUUC-Pop-099153	Populus trichocarpa	31.49	8.00e-35	141.00
IUUC-Pca-100460	Procavia capensis	81.57	0.00e+00	966.00
IUUC-Pva-102180	Pteropus vampyrus	91.83	0.00e+00	1070.00
IUUC-Pyt-104491	Pyrenophora triticirepentis	26.57	3.00e-05	42.40
IUUC-Rno-105907	Rattus norvegicus	91.48	0.00e+00	1068.00
IUUC-Sly-111482	Solanum lycopersicum	33.91	3.00e-39	156.00
IUUC-Sar-113112	Sorex araneus	77.92	8.00e-170	589.00
IUUC-Ssc-115448	Sus scrofa	83.30	0.00e+00	780.00
IUUC-Tgu-117293	Taeniopygia guttata	97.23	0.00e+00	1123.00
IUUC-Tru-117814	Takifugu rubripes	92.35	0.00e+00	1068.00
IUUC-Tni-120531	Tetraodon nigroviridis	94.78	0.00e+00	1095.00
IUUC-Tca-121074	Theobroma cacao	31.00	2.00e-35	144.00
IUUC-Tae-124075	Triticum aestivum	33.12	5.00e-40	159.00
IUUC-Tbe-127460	Tupaia belangeri	92.00	0.00e+00	1024.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence