iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	miRNAMap	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM	dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.30e-37	124.9	272	306

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf...sdtllvsGsdDgtikvWDlrtg 33
           Ht++v+cl+f   s+ +l++Gs D+t+ +WDlr  
   Q: 272  HTAEVNCLSFnpySEFILATGSADKTVALWDLRNL 306
           **********96554568*************9875 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MADKEAAFDD AVEERVINEE YKIWKKNTPF LYDLVMTHAL EWPSLTAQWL PDVTRPEGKD 60
FSIHRLVLGT HTSDEQNHLV IASVQLPNDD AQFDASHYDS EKGEFGGFGS VSGKIEIEIK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGCCGCCATG GCTGACAAGG AAGGTGAGTG TGCCGAGGCC GGCTCGGGAG GGTGCTGGGT 60
TTCGGGGCTG TGTCGTGGCC TGTTACGCGG CCTAAGACGG AGAGAAGGCC CGACTCTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR022052--Histone-bd_RBBP4_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12265--CAF1C_H4-bd
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0033186--C:CAF-1 complex
GO:0005829--C:cytosol
GO:0035098--C:ESC/E(Z) complex
GO:0000790--C:nuclear chromatin
GO:0005634--C:nucleus
GO:0016581--C:NuRD complex
GO:0016589--C:NURF complex
GO:0008094--F:DNA-dependent ATPase activity
GO:0031492--F:nucleosomal DNA binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980--F:RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0043044--P:ATP-dependent chromatin remodeling
GO:0006335--P:DNA replication-dependent nucleosome assembly
GO:0006336--P:DNA replication-independent nucleosome assembly
GO:0060416--P:response to growth hormone

KEGG

rno:313048

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000757	Aegilops tauschii	60.29	8.00e-141	493.00
IUUC-Aml-001339	Ailuropoda melanoleuca	99.29	0.00e+00	855.00
IUUC-Atr-003075	Amborella trichopoda	67.87	3.00e-171	594.00
IUUC-Apl-003952	Anas platyrhynchos	100.00	0.00e+00	868.00
IUUC-Aca-004508	Anolis carolinensis	98.82	0.00e+00	870.00
IUUC-Aly-006342	Arabidopsis lyrata	68.00	7.00e-166	576.00
IUUC-Ath-006855	Arabidopsis thaliana	68.25	3.00e-166	577.00
IUUC-Ago-007892	Ashbya gossypii	38.77	1.00e-79	290.00
IUUC-Acl-008163	Aspergillus clavatus	53.03	3.00e-125	441.00
IUUC-Afl-008645	Aspergillus flavus	52.99	4.00e-124	437.00
IUUC-Afu-009091	Aspergillus fumigatus	53.28	3.00e-125	441.00
IUUC-Ani-009478	Aspergillus nidulans	48.74	1.00e-103	369.00
IUUC-Ang-009707	Aspergillus niger	52.53	2.00e-120	425.00
IUUC-Aor-010028	Aspergillus oryzae	52.99	4.00e-124	437.00
IUUC-Ate-010416	Aspergillus terreus	51.34	3.00e-124	438.00
IUUC-Ame-010598	Astyanax mexicanus	96.93	0.00e+00	856.00
IUUC-Bgr-012001	Blumeria graminis	49.51	6.00e-108	384.00
IUUC-Bta-012851	Bos taurus	100.00	0.00e+00	879.00
IUUC-Bci-013815	Botrytis cinerea	50.12	3.00e-125	441.00
IUUC-Bdi-014926	Brachypodium distachyon	68.06	5.00e-164	570.00
IUUC-Bol-015856	Brassica oleracea	68.15	1.00e-165	576.00
IUUC-Bra-016725	Brassica rapa	63.00	1.00e-161	562.00
IUUC-Cel-018587	Caenorhabditis elegans	72.51	0.00e+00	631.00
IUUC-Cja-019884	Callithrix jacchus	100.00	0.00e+00	879.00
IUUC-Cfa-020343	Canis familiaris	100.00	0.00e+00	879.00
IUUC-Cpo-021591	Cavia porcellus	100.00	0.00e+00	879.00
IUUC-Cre-022563	Chlamydomonas reinhardtii	62.08	3.00e-157	548.00
IUUC-Cho-024506	Choloepus hoffmanni	99.53	0.00e+00	870.00
IUUC-Cin-025589	Ciona intestinalis	89.18	0.00e+00	802.00
IUUC-Csv-026216	Ciona savignyi	90.19	0.00e+00	806.00
IUUC-Cgl-026564	Colletotrichum gloeosporioides	48.55	1.00e-118	419.00
IUUC-Cne-026792	Cryptococcus neoformans	55.64	1.00e-134	472.00
IUUC-Cme-027307	Cyanidioschyzon merolae	52.20	7.00e-129	454.00
IUUC-Dre-028742	Danio rerio	97.41	0.00e+00	858.00
IUUC-Dno-029114	Dasypus novemcinctus	100.00	0.00e+00	879.00
IUUC-Dse-031282	Dothistroma septosporum	47.15	2.00e-102	366.00
IUUC-Dme-032126	Drosophila melanogaster	91.93	0.00e+00	800.00
IUUC-Ete-032731	Echinops telfairi	100.00	0.00e+00	879.00
IUUC-Eca-033533	Equus caballus	98.57	0.00e+00	850.00
IUUC-Eeu-034644	Erinaceus europaeus	100.00	2.00e-130	459.00
IUUC-Fca-036202	Felis catus	100.00	0.00e+00	879.00
IUUC-Fal-037084	Ficedula albicollis	100.00	0.00e+00	869.00
IUUC-Fox-037974	Fusarium oxysporum	50.12	2.00e-123	435.00
IUUC-Fso-038246	Fusarium solani	48.32	5.00e-111	394.00
IUUC-Gmo-039214	Gadus morhua	97.16	0.00e+00	848.00
IUUC-Ggr-039741	Gaeumannomyces graminis	50.36	5.00e-119	421.00
IUUC-Gga-040396	Gallus gallus	100.00	0.00e+00	879.00
IUUC-Gac-041389	Gasterosteus aculeatus	95.75	0.00e+00	840.00
IUUC-Gma-042791	Glycine max	68.17	8.00e-164	569.00
IUUC-Ggo-045422	Gorilla gorilla	91.59	0.00e+00	782.00
IUUC-Hsa-045683	Homo sapiens	100.00	0.00e+00	879.00
IUUC-Hvu-047457	Hordeum vulgare	67.18	3.00e-76	277.00
IUUC-Itr-047950	Ictidomys tridecemlineatus	100.00	0.00e+00	879.00
IUUC-Kpa-049119	Komagataella pastoris	37.19	3.00e-72	265.00
IUUC-Lch-050545	Latimeria chalumnae	93.38	0.00e+00	824.00
IUUC-Lpe-051337	Leersia perrieri	68.55	7.00e-165	573.00
IUUC-Loc-052473	Lepisosteus oculatus	97.88	0.00e+00	863.00
IUUC-Lma-053275	Leptosphaeria maculans	45.33	4.00e-69	254.00
IUUC-Laf-054114	Loxodonta africana	100.00	0.00e+00	879.00
IUUC-Mcc-055648	Macaca mulatta	99.76	0.00e+00	872.00
IUUC-Meu-056490	Macropus eugenii	100.00	0.00e+00	879.00
IUUC-Mor-056947	Magnaporthe oryzae	50.96	2.00e-117	416.00
IUUC-Mpo-057602	Magnaporthe poae	49.64	3.00e-118	418.00
IUUC-Mtr-057853	Medicago truncatula	67.00	1.00e-161	562.00
IUUC-Mla-058884	Melampsora laricipopulina	52.67	7.00e-128	450.00
IUUC-Mga-059452	Meleagris gallopavo	100.00	0.00e+00	869.00
IUUC-Mvi-060450	Microbotryum violaceum	57.52	4.00e-137	481.00
IUUC-Mmr-060678	Microcebus murinus	99.75	0.00e+00	830.00
IUUC-Mdo-062450	Monodelphis domestica	99.51	0.00e+00	838.00
IUUC-Mmu-063282	Mus musculus	100.00	0.00e+00	879.00
IUUC-Mac-065480	Musa acuminata	67.25	5.00e-162	563.00
IUUC-Mpu-066529	Mustela putorius furo	99.06	0.00e+00	872.00
IUUC-Mlu-068072	Myotis lucifugus	100.00	0.00e+00	879.00
IUUC-Nfi-068374	Neosartorya fischeri	53.28	7.00e-122	430.00
IUUC-Ncr-068794	Neurospora crassa	48.04	3.00e-115	408.00
IUUC-Nle-069577	Nomascus leucogenys	100.00	0.00e+00	879.00
IUUC-Opr-070245	Ochotona princeps	84.47	0.00e+00	697.00
IUUC-Ont-071809	Oreochromis niloticus	96.70	0.00e+00	855.00
IUUC-Oan-072839	Ornithorhynchus anatinus	99.76	0.00e+00	864.00
IUUC-Ocu-074515	Oryctolagus cuniculus	94.12	0.00e+00	764.00
IUUC-Oba-075719	Oryza barthii	57.82	8.00e-137	480.00
IUUC-Obr-076859	Oryza brachyantha	68.14	6.00e-163	566.00
IUUC-Ogl-077920	Oryza glaberrima	68.06	1.00e-164	572.00
IUUC-Ogu-078048	Oryza glumaepatula	57.82	6.00e-136	478.00
IUUC-Oin-079960	Oryza indica	56.27	3.00e-124	439.00
IUUC-Olo-080553	Oryza longistaminata	55.45	2.00e-132	466.00
IUUC-Ome-081835	Oryza meridionalis	68.06	3.00e-165	575.00
IUUC-Oni-082494	Oryza nivara	57.58	5.00e-135	474.00
IUUC-Opu-083913	Oryza punctata	65.36	1.00e-153	535.00
IUUC-Oru-084666	Oryza rufipogon	68.06	1.00e-164	572.00
IUUC-Osa-085884	Oryza sativa	68.06	1.00e-164	572.00
IUUC-Ola-086664	Oryzias latipes	96.47	0.00e+00	849.00
IUUC-Olu-087579	Ostreococcus lucimarinus	63.43	1.00e-145	509.00
IUUC-Oga-088364	Otolemur garnettii	91.10	0.00e+00	791.00
IUUC-Oar-089652	Ovis aries	100.00	0.00e+00	879.00
IUUC-Psi-093300	Pelodiscus sinensis	100.00	0.00e+00	806.00
IUUC-Pma-094307	Petromyzon marinus	93.78	0.00e+00	824.00
IUUC-Pno-095153	Phaeosphaeria nodorum	48.43	2.00e-109	389.00
IUUC-Ppa-095800	Physcomitrella patens	68.17	1.00e-169	589.00
IUUC-Pfo-097376	Poecilia formosa	96.47	0.00e+00	850.00
IUUC-Pab-097697	Pongo abelii	100.00	0.00e+00	879.00
IUUC-Pop-099709	Populus trichocarpa	65.70	2.00e-166	578.00
IUUC-Pca-100642	Procavia capensis	89.85	0.00e+00	737.00
IUUC-Ppe-101212	Prunus persica	66.50	7.00e-165	573.00
IUUC-Pva-102253	Pteropus vampyrus	100.00	0.00e+00	879.00
IUUC-Pgr-103441	Puccinia graminis	54.22	4.00e-123	434.00
IUUC-Pte-104332	Pyrenophora teres	48.90	5.00e-112	397.00
IUUC-Pyt-104516	Pyrenophora triticirepentis	48.90	6.00e-112	397.00
IUUC-Sce-106364	Saccharomyces cerevisiae	37.84	2.00e-71	262.00
IUUC-Sha-106663	Sarcophilus harrisii	100.00	0.00e+00	869.00
IUUC-Sja-108001	Schizosaccharomyces japonicus	47.79	1.00e-106	379.00
IUUC-Spo-108145	Schizosaccharomyces pombe	52.22	1.00e-119	423.00
IUUC-Smo-109159	Selaginella moellendorffii	65.45	3.00e-164	571.00
IUUC-Sit-110144	Setaria italica	68.00	2.00e-155	542.00
IUUC-Sly-111680	Solanum lycopersicum	66.18	3.00e-166	578.00
IUUC-Stu-111931	Solanum tuberosum	65.94	6.00e-165	573.00
IUUC-Sbi-114637	Sorghum bicolor	68.25	5.00e-163	567.00
IUUC-Sre-114980	Sporisorium reilianum	54.29	2.00e-137	482.00
IUUC-Ssc-115711	Sus scrofa	100.00	0.00e+00	806.00
IUUC-Tgu-116925	Taeniopygia guttata	99.76	0.00e+00	868.00
IUUC-Tru-117549	Takifugu rubripes	96.01	0.00e+00	844.00
IUUC-Tni-120398	Tetraodon nigroviridis	96.01	0.00e+00	848.00
IUUC-Tca-121841	Theobroma cacao	68.25	1.00e-165	575.00
IUUC-Tre-122190	Trichoderma reesei	50.36	2.00e-115	409.00
IUUC-Tvi-122304	Trichoderma virens	49.64	1.00e-123	436.00
IUUC-Tae-124648	Triticum aestivum	67.32	8.00e-156	543.00
IUUC-Tur-126850	Triticum urartu	63.55	4.00e-117	414.00
IUUC-Tme-126949	Tuber melanosporum	54.89	2.00e-129	455.00
IUUC-Uma-129424	Ustilago maydis	53.15	2.00e-137	482.00
IUUC-Vda-129873	Verticillium dahliae	49.88	5.00e-125	441.00
IUUC-Vpa-130079	Vicugna pacos	99.53	0.00e+00	873.00
IUUC-Vvi-131585	Vitis vinifera	67.25	2.00e-163	568.00
IUUC-Xma-133066	Xiphophorus maculatus	96.70	0.00e+00	855.00
IUUC-Yli-134334	Yarrowia lipolytica	39.43	9.00e-81	293.00
IUUC-Zma-135710	Zea mays	67.50	5.00e-156	543.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence