iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	TRANSFAC	miRNAMap	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus	UniProt
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	8.80e-21	73.5	396	435

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllks 38
           gH+d v+cl+  ++   l+sGsdDgt+++W++ t ++ k+
   Q: 396  GHSDLVRCLSVsPGgQWLASGSDDGTLRLWEVATARCMKT 435
           8**********988899*******************9875 PP

Organism

Rattus norvegicus

Functional Description
(View)

Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.

Protein Sequence
(Fasta)

MAGACGKHHM SPGSLPGKRR LEPDQEPQIQ EPLLLSDPDS SLSDSEESVF SGLEDSGSDT 60
SDEDTEEVAR AGCDKDNRTE KTSEEQEQAV PPCPRAEEAG ALTRDEYEED SSDEEDIRNT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGCAGCATG GCGGGGGCGT GTGGTAAGCA CCACATGTCA CCGGGATCGC TGCCAGGGAA 60
ACGGCGTTTG GAACCTGATC AGGAGCCACA GATACAAGAG GTAACTTCGA GGTAGCGGGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR028598--BOP1/Erb1
IPR012953--BOP1_N_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08145--BOP1NT
PF00400--WD40

SMART

SM01035--BOP1NT
SM00320--WD40

Gene Ontology

GO:0005654--C:nucleoplasm
GO:0070545--C:PeBoW complex
GO:0030687--C:preribosome, large subunit precursor
GO:0043021--F:ribonucleoprotein complex binding
GO:0003723--F:RNA binding
GO:0008283--P:cell proliferation
GO:0000448--P:cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000463--P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0051726--P:regulation of cell cycle

KEGG

rno:300050

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-001158	Aegilops tauschii	41.58	2.00e-124	439.00
IUUC-Aml-001507	Ailuropoda melanoleuca	80.78	0.00e+00	1042.00
IUUC-Atr-003141	Amborella trichopoda	42.02	9.00e-88	317.00
IUUC-Apl-003545	Anas platyrhynchos	67.13	0.00e+00	806.00
IUUC-Aly-005649	Arabidopsis lyrata	45.02	2.00e-157	549.00
IUUC-Ath-007625	Arabidopsis thaliana	45.28	1.00e-155	543.00
IUUC-Ago-007958	Ashbya gossypii	43.97	2.00e-163	569.00
IUUC-Acl-008344	Aspergillus clavatus	43.72	1.00e-143	503.00
IUUC-Afl-008616	Aspergillus flavus	43.26	1.00e-146	513.00
IUUC-Afu-009083	Aspergillus fumigatus	44.50	6.00e-142	498.00
IUUC-Ani-009365	Aspergillus nidulans	43.57	5.00e-145	508.00
IUUC-Ang-009796	Aspergillus niger	43.57	1.00e-142	500.00
IUUC-Aor-010015	Aspergillus oryzae	43.26	1.00e-146	513.00
IUUC-Ate-010537	Aspergillus terreus	44.72	1.00e-149	523.00
IUUC-Ame-011767	Astyanax mexicanus	68.80	2.00e-114	404.00
IUUC-Bgr-012286	Blumeria graminis	42.86	1.00e-149	523.00
IUUC-Bta-013569	Bos taurus	83.80	0.00e+00	1103.00
IUUC-Bci-013820	Botrytis cinerea	42.25	9.00e-141	494.00
IUUC-Bdi-014895	Brachypodium distachyon	45.78	7.00e-155	540.00
IUUC-Bol-016099	Brassica oleracea	45.31	3.00e-159	555.00
IUUC-Bra-017174	Brassica rapa	45.15	6.00e-159	555.00
IUUC-Cel-018201	Caenorhabditis elegans	47.19	7.00e-158	550.00
IUUC-Cja-019009	Callithrix jacchus	76.30	0.00e+00	952.00
IUUC-Cfa-020173	Canis familiaris	81.29	0.00e+00	1015.00
IUUC-Cpo-021796	Cavia porcellus	88.18	0.00e+00	1105.00
IUUC-Cre-022650	Chlamydomonas reinhardtii	47.93	3.00e-154	538.00
IUUC-Csa-023440	Chlorocebus sabaeus	88.50	0.00e+00	1154.00
IUUC-Cin-025782	Ciona intestinalis	55.61	0.00e+00	754.00
IUUC-Csv-026352	Ciona savignyi	56.57	0.00e+00	739.00
IUUC-Cgl-026393	Colletotrichum gloeosporioides	39.37	1.00e-115	410.00
IUUC-Cne-027004	Cryptococcus neoformans	45.38	3.00e-170	592.00
IUUC-Cme-027242	Cyanidioschyzon merolae	39.18	4.00e-124	438.00
IUUC-Dre-028658	Danio rerio	73.54	0.00e+00	984.00
IUUC-Dno-028883	Dasypus novemcinctus	81.38	0.00e+00	1070.00
IUUC-Dor-031031	Dipodomys ordii	88.19	0.00e+00	1132.00
IUUC-Dse-031443	Dothistroma septosporum	40.40	5.00e-144	504.00
IUUC-Dme-031786	Drosophila melanogaster	53.10	0.00e+00	725.00
IUUC-Eca-033677	Equus caballus	86.28	0.00e+00	1129.00
IUUC-Eeu-035310	Erinaceus europaeus	84.66	0.00e+00	914.00
IUUC-Fca-035888	Felis catus	84.50	0.00e+00	1080.00
IUUC-Fal-037438	Ficedula albicollis	67.96	0.00e+00	741.00
IUUC-Fox-037973	Fusarium oxysporum	44.87	3.00e-158	552.00
IUUC-Fso-038187	Fusarium solani	44.71	6.00e-158	551.00
IUUC-Gmo-039114	Gadus morhua	65.15	0.00e+00	837.00
IUUC-Ggr-039746	Gaeumannomyces graminis	42.75	2.00e-153	536.00
IUUC-Gga-040631	Gallus gallus	73.45	1.00e-158	552.00
IUUC-Gac-042582	Gasterosteus aculeatus	65.89	0.00e+00	882.00
IUUC-Gma-044215	Glycine max	45.06	2.00e-149	522.00
IUUC-Ggo-045587	Gorilla gorilla	90.08	0.00e+00	1137.00
IUUC-Hsa-046319	Homo sapiens	88.80	0.00e+00	1159.00
IUUC-Hvu-047526	Hordeum vulgare	45.31	1.00e-147	516.00
IUUC-Itr-048683	Ictidomys tridecemlineatus	87.99	0.00e+00	1136.00
IUUC-Kpa-049221	Komagataella pastoris	43.38	3.00e-154	539.00
IUUC-Lch-049640	Latimeria chalumnae	74.47	0.00e+00	1005.00
IUUC-Lpe-051135	Leersia perrieri	43.02	5.00e-136	478.00
IUUC-Loc-051930	Lepisosteus oculatus	73.33	0.00e+00	987.00
IUUC-Lma-053290	Leptosphaeria maculans	41.25	2.00e-145	509.00
IUUC-Laf-053903	Loxodonta africana	70.20	0.00e+00	967.00
IUUC-Mcc-055471	Macaca mulatta	88.04	0.00e+00	1147.00
IUUC-Meu-056190	Macropus eugenii	82.76	0.00e+00	1045.00
IUUC-Mor-057135	Magnaporthe oryzae	42.50	2.00e-145	509.00
IUUC-Mpo-057475	Magnaporthe poae	42.68	5.00e-142	498.00
IUUC-Mtr-058689	Medicago truncatula	41.52	7.00e-134	471.00
IUUC-Mla-059149	Melampsora laricipopulina	45.85	8.00e-169	587.00
IUUC-Mga-059645	Meleagris gallopavo	63.52	1.00e-99	355.00
IUUC-Mvi-060485	Microbotryum violaceum	45.78	6.00e-147	515.00
IUUC-Mmr-061674	Microcebus murinus	88.46	0.00e+00	1090.00
IUUC-Mdo-062973	Monodelphis domestica	81.63	0.00e+00	1061.00
IUUC-Mmu-064180	Mus musculus	93.72	0.00e+00	1288.00
IUUC-Mac-064535	Musa acuminata	42.33	4.00e-98	352.00
IUUC-Mpu-066406	Mustela putorius furo	86.22	0.00e+00	1122.00
IUUC-Mlu-067795	Myotis lucifugus	88.05	0.00e+00	1106.00
IUUC-Nfi-068516	Neosartorya fischeri	44.19	4.00e-134	472.00
IUUC-Ncr-068767	Neurospora crassa	43.71	2.00e-139	489.00
IUUC-Opr-071084	Ochotona princeps	85.00	6.00e-142	496.00
IUUC-Ont-071614	Oreochromis niloticus	68.66	0.00e+00	919.00
IUUC-Oba-075980	Oryza barthii	43.00	4.00e-136	478.00
IUUC-Obr-076799	Oryza brachyantha	45.53	4.00e-151	528.00
IUUC-Ogl-077134	Oryza glaberrima	45.06	4.00e-145	508.00
IUUC-Ogu-078655	Oryza glumaepatula	43.76	2.00e-140	493.00
IUUC-Oin-079654	Oryza indica	45.06	7.00e-145	507.00
IUUC-Olo-080706	Oryza longistaminata	42.83	4.00e-137	481.00
IUUC-Ome-081716	Oryza meridionalis	39.06	1.00e-116	414.00
IUUC-Oni-082508	Oryza nivara	43.85	6.00e-138	484.00
IUUC-Opu-083707	Oryza punctata	42.83	4.00e-136	478.00
IUUC-Oru-084453	Oryza rufipogon	42.83	4.00e-137	481.00
IUUC-Osa-085811	Oryza sativa	45.06	4.00e-145	508.00
IUUC-Ola-087361	Oryzias latipes	69.52	0.00e+00	917.00
IUUC-Oga-088015	Otolemur garnettii	87.29	0.00e+00	1145.00
IUUC-Oar-090058	Ovis aries	90.48	3.00e-88	318.00
IUUC-Ptr-090631	Pan troglodytes	81.05	4.00e-138	484.00
IUUC-Pan-092306	Papio anubis	88.21	0.00e+00	1147.00
IUUC-Pma-094622	Petromyzon marinus	71.87	0.00e+00	966.00
IUUC-Pno-094794	Phaeosphaeria nodorum	39.87	2.00e-134	472.00
IUUC-Ppa-095528	Physcomitrella patens	43.76	1.00e-96	347.00
IUUC-Pfo-096682	Poecilia formosa	69.19	0.00e+00	927.00
IUUC-Pab-097939	Pongo abelii	88.99	0.00e+00	1022.00
IUUC-Pop-099530	Populus trichocarpa	46.03	5.00e-142	498.00
IUUC-Pca-100333	Procavia capensis	84.32	0.00e+00	1092.00
IUUC-Ppe-102078	Prunus persica	44.73	6.00e-152	531.00
IUUC-Pgr-103525	Puccinia graminis	46.18	1.00e-162	566.00
IUUC-Ptt-103929	Puccinia triticina	45.78	9.00e-158	551.00
IUUC-Pte-104029	Pyrenophora teres	42.81	4.00e-154	538.00
IUUC-Pyt-104446	Pyrenophora triticirepentis	42.97	3.00e-154	538.00
IUUC-Sce-106381	Saccharomyces cerevisiae	41.55	1.00e-155	543.00
IUUC-Sha-106519	Sarcophilus harrisii	82.93	0.00e+00	1065.00
IUUC-Sja-107908	Schizosaccharomyces japonicus	41.86	2.00e-142	499.00
IUUC-Spo-108071	Schizosaccharomyces pombe	42.50	1.00e-139	490.00
IUUC-Smo-109604	Selaginella moellendorffii	46.93	3.00e-157	548.00
IUUC-Sit-110551	Setaria italica	44.88	5.00e-148	518.00
IUUC-Sly-110970	Solanum lycopersicum	47.23	6.00e-84	304.00
IUUC-Stu-112593	Solanum tuberosum	45.87	2.00e-156	546.00
IUUC-Sar-113123	Sorex araneus	85.40	9.00e-149	519.00
IUUC-Sbi-113945	Sorghum bicolor	44.07	2.00e-151	529.00
IUUC-Sre-115188	Sporisorium reilianum	44.65	8.00e-159	554.00
IUUC-Ssc-115352	Sus scrofa	88.29	0.00e+00	1081.00
IUUC-Tru-117685	Takifugu rubripes	70.23	0.00e+00	934.00
IUUC-Tni-119982	Tetraodon nigroviridis	69.94	0.00e+00	900.00
IUUC-Tca-121664	Theobroma cacao	46.19	1.00e-158	553.00
IUUC-Tre-122229	Trichoderma reesei	44.01	6.00e-140	491.00
IUUC-Tvi-122576	Trichoderma virens	44.11	6.00e-143	501.00
IUUC-Tae-124110	Triticum aestivum	44.61	8.00e-138	484.00
IUUC-Tur-126781	Triticum urartu	41.91	5.00e-121	428.00
IUUC-Tme-127080	Tuber melanosporum	46.81	9.00e-172	597.00
IUUC-Ttr-128514	Tursiops truncatus	83.48	0.00e+00	777.00
IUUC-Uma-129556	Ustilago maydis	43.81	6.00e-154	538.00
IUUC-Vda-129715	Verticillium dahliae	44.32	2.00e-152	532.00
IUUC-Vvi-131211	Vitis vinifera	44.78	2.00e-148	519.00
IUUC-Xma-133883	Xiphophorus maculatus	69.14	0.00e+00	892.00
IUUC-Yli-134438	Yarrowia lipolytica	43.71	2.00e-145	509.00
IUUC-Zma-135341	Zea mays	35.49	1.00e-88	321.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence