iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bci-013865

Ensembl Protein ID

Bcin16g02100.1

UniProt Accession

A6S5X1; URM1_BOTFB

Genbank Protein ID

EDN28264.1

Protein Name

Ubiquitin-related modifier 1

Genbank Nucleotide ID

CH476888

Gene Name

urm1; BC1G_08187

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bcin16g02100	Bcin16g02100.1	Bcin16g02100.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	47.06	2.00e-21	95.10	IUUC-Sce-106366

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Botrytis cinerea

Functional Description
(View)

Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.

Protein Sequence
(Fasta)

MATDTLSIVV EFTGGLEMLF SDQRSHKLSV PKTDSKGAPV TVGWLVNYLC DEIMQDSRKD 60
MFVLDDHVRP GILVLINDAD WELEGEASYE LQSNDNILFV STLHGG 106

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Nucleotide Sequence
(Fasta)

GGCGCAAACC ACAACCTCAG TATATCAAAA CCTCCAAAAA TCCCAAAGTC CACAACATAC 60
CGTCAAAATG GCGACAGATA CCCTCTCTAT CGTCGTAGAA TTCACGTACG CCTCTTATAT 120

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Sequence Source

Ensembl

Keyword

KW-0963--Cytoplasm
KW-1017--Isopeptide bond
KW-0819--tRNA processing
KW-0833--Ubl conjugation pathway

Interpro

IPR012675--Beta-grasp_dom
IPR016155--Mopterin_synth/thiamin_S_b
IPR015221--Urm1

Pfam

PF09138--Urm1

Gene Ontology

GO:0005737--C:cytoplasm
GO:0034227--P:tRNA thio-modification

KEGG

bfu:BC1G_08187

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002254	Ailuropoda melanoleuca	45.54	9.00e-22	93.20
IUUC-Atr-003089	Amborella trichopoda	45.54	2.00e-22	95.10
IUUC-Apl-003382	Anas platyrhynchos	46.32	8.00e-21	89.70
IUUC-Aca-004981	Anolis carolinensis	46.53	5.00e-22	94.00
IUUC-Aly-005517	Arabidopsis lyrata	39.36	3.00e-15	71.20
IUUC-Ath-006718	Arabidopsis thaliana	57.14	4.00e-13	64.30
IUUC-Ago-007917	Ashbya gossypii	47.06	9.00e-23	96.30
IUUC-Acl-008054	Aspergillus clavatus	73.58	8.00e-21	89.40
IUUC-Afl-008704	Aspergillus flavus	59.55	9.00e-30	119.00
IUUC-Aor-009890	Aspergillus oryzae	60.95	5.00e-36	140.00
IUUC-Bta-012448	Bos taurus	45.54	6.00e-22	94.00
IUUC-Bdi-014980	Brachypodium distachyon	42.35	1.00e-14	69.70
IUUC-Bol-016055	Brassica oleracea	55.10	4.00e-13	64.30
IUUC-Bra-016845	Brassica rapa	55.10	4.00e-13	64.30
IUUC-Cel-018485	Caenorhabditis elegans	33.33	2.00e-09	52.40
IUUC-Cja-019587	Callithrix jacchus	46.53	5.00e-22	94.00
IUUC-Cfa-020653	Canis familiaris	46.53	4.00e-22	94.40
IUUC-Cpo-021622	Cavia porcellus	46.53	5.00e-22	94.00
IUUC-Cre-023015	Chlamydomonas reinhardtii	42.57	2.00e-20	89.00
IUUC-Csa-023756	Chlorocebus sabaeus	41.77	6.00e-13	64.70
IUUC-Cgl-026518	Colletotrichum gloeosporioides	65.35	4.00e-40	154.00
IUUC-Cne-026953	Cryptococcus neoformans	47.17	9.00e-24	100.00
IUUC-Cme-027314	Cyanidioschyzon merolae	41.58	8.00e-15	69.70
IUUC-Dre-027884	Danio rerio	44.55	9.00e-21	90.10
IUUC-Dno-029262	Dasypus novemcinctus	40.48	2.00e-12	63.50
IUUC-Dor-030601	Dipodomys ordii	55.10	4.00e-09	50.80
IUUC-Dme-031893	Drosophila melanogaster	48.11	2.00e-22	95.50
IUUC-Ete-032773	Echinops telfairi	46.00	3.00e-21	91.70
IUUC-Eca-034187	Equus caballus	47.52	3.00e-22	94.70
IUUC-Eeu-034808	Erinaceus europaeus	46.53	5.00e-22	94.00
IUUC-Fca-036107	Felis catus	47.52	1.00e-22	95.90
IUUC-Fal-036607	Ficedula albicollis	44.21	5.00e-20	87.00
IUUC-Fox-037698	Fusarium oxysporum	68.32	8.00e-41	156.00
IUUC-Gmo-039492	Gadus morhua	44.55	4.00e-21	91.30
IUUC-Ggr-039965	Gaeumannomyces graminis	65.69	1.00e-38	150.00
IUUC-Gga-041268	Gallus gallus	46.08	2.00e-22	95.10
IUUC-Gac-042111	Gasterosteus aculeatus	47.52	4.00e-22	94.40
IUUC-Gma-043240	Glycine max	55.10	5.00e-13	63.90
IUUC-Ggo-045176	Gorilla gorilla	41.46	2.00e-11	60.10
IUUC-Hsa-046077	Homo sapiens	46.15	3.00e-20	88.20
IUUC-Itr-048111	Ictidomys tridecemlineatus	44.79	3.00e-17	78.20
IUUC-Kpa-049157	Komagataella pastoris	47.06	2.00e-20	88.60
IUUC-Lch-049889	Latimeria chalumnae	41.58	6.00e-20	87.00
IUUC-Lpe-050783	Leersia perrieri	41.46	3.00e-13	64.70
IUUC-Loc-052400	Lepisosteus oculatus	45.54	1.00e-21	92.80
IUUC-Lma-053259	Leptosphaeria maculans	62.26	6.00e-39	150.00
IUUC-Laf-053596	Loxodonta africana	45.63	3.00e-21	91.70
IUUC-Mcc-054845	Macaca mulatta	42.72	5.00e-19	84.00
IUUC-Meu-055968	Macropus eugenii	48.51	2.00e-23	98.60
IUUC-Mor-057126	Magnaporthe oryzae	67.65	2.00e-40	155.00
IUUC-Mpo-057311	Magnaporthe poae	67.31	9.00e-40	154.00
IUUC-Mtr-058266	Medicago truncatula	38.82	1.00e-13	66.60
IUUC-Mla-058847	Melampsora laricipopulina	33.02	4.00e-11	58.20
IUUC-Mga-059468	Meleagris gallopavo	46.32	6.00e-21	90.10
IUUC-Mvi-060235	Microbotryum violaceum	33.11	3.00e-16	75.90
IUUC-Mdo-061948	Monodelphis domestica	48.51	4.00e-23	97.80
IUUC-Mmu-063946	Mus musculus	46.08	9.00e-22	93.20
IUUC-Mac-064812	Musa acuminata	61.22	2.00e-14	68.60
IUUC-Mpu-066763	Mustela putorius furo	47.52	3.00e-22	94.70
IUUC-Mlu-066970	Myotis lucifugus	41.77	4.00e-13	63.90
IUUC-Ncr-068824	Neurospora crassa	61.39	3.00e-35	138.00
IUUC-Nle-069849	Nomascus leucogenys	41.77	5.00e-13	65.10
IUUC-Opr-070227	Ochotona princeps	46.53	5.00e-22	94.00
IUUC-Ont-072530	Oreochromis niloticus	46.08	2.00e-22	95.10
IUUC-Oan-073191	Ornithorhynchus anatinus	46.24	7.00e-20	86.70
IUUC-Ocu-074460	Oryctolagus cuniculus	47.52	1.00e-22	95.50
IUUC-Oba-075499	Oryza barthii	43.37	8.00e-14	67.80
IUUC-Obr-076896	Oryza brachyantha	40.96	5.00e-13	65.90
IUUC-Ogl-077834	Oryza glaberrima	44.19	2.00e-14	68.60
IUUC-Ogu-078622	Oryza glumaepatula	44.19	2.00e-14	68.60
IUUC-Oin-079358	Oryza indica	44.19	9.00e-14	68.20
IUUC-Olo-081035	Oryza longistaminata	42.86	3.00e-16	75.90
IUUC-Oni-082425	Oryza nivara	44.19	2.00e-14	68.60
IUUC-Opu-083461	Oryza punctata	44.71	9.00e-14	67.80
IUUC-Oru-084875	Oryza rufipogon	51.79	3.00e-11	57.80
IUUC-Ola-087247	Oryzias latipes	40.00	2.40e+00	25.80
IUUC-Oga-089128	Otolemur garnettii	47.52	4.00e-22	94.40
IUUC-Oar-089896	Ovis aries	45.54	6.00e-22	94.00
IUUC-Ptr-091618	Pan troglodytes	41.46	2.00e-11	60.10
IUUC-Pan-092238	Papio anubis	41.77	6.00e-13	64.70
IUUC-Psi-093879	Pelodiscus sinensis	46.53	6.00e-23	97.10
IUUC-Pma-094484	Petromyzon marinus	43.37	3.00e-15	71.60
IUUC-Ppa-095801	Physcomitrella patens	44.05	8.00e-16	73.60
IUUC-Pfo-097192	Poecilia formosa	45.54	1.00e-20	89.70
IUUC-Pab-098203	Pongo abelii	46.15	4.00e-20	87.80
IUUC-Pop-099614	Populus trichocarpa	57.14	7.00e-14	66.60
IUUC-Pca-100507	Procavia capensis	40.51	6.00e-13	63.50
IUUC-Ppe-101174	Prunus persica	38.61	4.00e-17	77.80
IUUC-Pva-102735	Pteropus vampyrus	46.53	5.00e-19	84.00
IUUC-Pgr-103510	Puccinia graminis	40.00	5.00e-16	74.70
IUUC-Ptt-103918	Puccinia triticina	37.74	5.00e-14	67.80
IUUC-Pte-104173	Pyrenophora teres	63.73	4.00e-38	147.00
IUUC-Pyt-104806	Pyrenophora triticirepentis	63.73	3.00e-38	148.00
IUUC-Rno-105820	Rattus norvegicus	46.53	2.00e-21	92.40
IUUC-Sce-106366	Saccharomyces cerevisiae	47.06	2.00e-22	95.10
IUUC-Sja-107727	Schizosaccharomyces japonicus	47.47	1.00e-21	93.20
IUUC-Spo-108074	Schizosaccharomyces pombe	44.55	2.00e-17	79.00
IUUC-Smo-108944	Selaginella moellendorffii	38.71	1.00e-15	72.40
IUUC-Sit-110277	Setaria italica	45.78	9.00e-16	73.20
IUUC-Sly-111505	Solanum lycopersicum	40.96	6.00e-15	70.50
IUUC-Stu-112076	Solanum tuberosum	40.96	7.00e-15	70.10
IUUC-Sbi-114274	Sorghum bicolor	41.76	5.00e-15	70.90
IUUC-Sre-114953	Sporisorium reilianum	48.60	8.00e-27	110.00
IUUC-Ssc-115418	Sus scrofa	49.50	9.00e-23	96.70
IUUC-Tgu-117311	Taeniopygia guttata	44.21	5.00e-20	87.00
IUUC-Tru-118598	Takifugu rubripes	44.68	5.00e-20	87.00
IUUC-Tni-120109	Tetraodon nigroviridis	42.16	2.00e-18	82.40
IUUC-Tca-120942	Theobroma cacao	43.06	2.00e-13	65.50
IUUC-Tre-122099	Trichoderma reesei	69.15	3.00e-32	127.00
IUUC-Tvi-122285	Trichoderma virens	65.71	3.00e-34	135.00
IUUC-Tae-125193	Triticum aestivum	43.37	9.00e-15	69.70
IUUC-Tur-126677	Triticum urartu	37.89	5.00e-12	60.80
IUUC-Tme-127120	Tuber melanosporum	60.58	2.00e-36	142.00
IUUC-Tbe-128050	Tupaia belangeri	40.59	4.00e-16	74.30
IUUC-Ttr-129019	Tursiops truncatus	47.52	3.00e-22	94.70
IUUC-Uma-129483	Ustilago maydis	47.22	6.00e-26	107.00
IUUC-Vda-129690	Verticillium dahliae	52.68	4.00e-31	124.00
IUUC-Vvi-131174	Vitis vinifera	57.14	3.00e-13	64.70
IUUC-Xma-133862	Xiphophorus maculatus	45.54	1.00e-20	89.70
IUUC-Yli-134398	Yarrowia lipolytica	48.57	7.00e-24	100.00
IUUC-Zma-134964	Zea mays	42.17	2.00e-15	72.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence