iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000030176.2	ENSCAFT00000047572.2	ENSCAFP00000041311.1
ENSCAFG00000030176.2	ENSCAFT00000002283.3	ENSCAFP00000002119.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	3.90e-07	30.8	405	443

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C+iC e f +  ++l+C H f+  C++ w       +++  CP+Cr
   Q: 405  CIICSEYFIE-AVTLNCAHSFCSYCINEW------MKRKVECPICR 443
           ********99.899***************......**********8 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MEEPGSLVTG DRAGGRRWCL RRARMNAEWL LLEDGNEVTI GRGFGVTYQL VSKICPLMIS 60
RNHCVLKQNV EGQWTIMDNK SLNGVWLNRE RLEPLKVYSI HKGDHIQLGV PLENKENAEY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCGGTTGG CGGCCGAGGG GGCGGGGCGC GCAGCCCGAG CGAGAGTTCA CATCGATCGC 60
GAGCGCGTAG CGATTGCTTC TGTCTGTTGT TTAGTTATGG CGCCGGCGAC GAGGCTGAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0156--Chromatin regulator
KW-0158--Chromosome
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0227--DNA damage
KW-0234--DNA repair
KW-0479--Metal-binding
KW-0498--Mitosis
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0779--Telomere
KW-0808--Transferase
KW-0832--Ubl conjugation
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000253--FHA_dom
IPR017335--RNF8
IPR008984--SMAD_FHA_domain
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50006--FHA_DOMAIN
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00498--FHA
PF00097--zf-C3HC4

SMART

SM00240--FHA
SM00184--RING

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0035861--C:site of double-strand break
GO:0000151--C:ubiquitin ligase complex
GO:0003682--F:chromatin binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0006302--P:double-strand break repair
GO:0070535--P:histone H2A K63-linked ubiquitination
GO:0034244--P:negative regulation of transcription elongation from RNA polymerase II promoter
GO:0045739--P:positive regulation of DNA repair
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0010212--P:response to ionizing radiation
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

cfa:481775

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002124	Ailuropoda melanoleuca	90.48	0.00e+00	707.00
IUUC-Apl-003664	Anas platyrhynchos	78.89	6.00e-39	152.00
IUUC-Aca-005036	Anolis carolinensis	57.41	6.00e-122	431.00
IUUC-Ame-011537	Astyanax mexicanus	41.46	6.00e-85	308.00
IUUC-Bta-013297	Bos taurus	86.63	0.00e+00	650.00
IUUC-Cja-019201	Callithrix jacchus	83.13	0.00e+00	650.00
IUUC-Csa-024133	Chlorocebus sabaeus	84.98	0.00e+00	701.00
IUUC-Cho-024624	Choloepus hoffmanni	81.34	2.00e-144	504.00
IUUC-Dre-027918	Danio rerio	42.59	2.00e-82	300.00
IUUC-Dno-029774	Dasypus novemcinctus	87.06	0.00e+00	723.00
IUUC-Dor-030190	Dipodomys ordii	75.56	8.00e-154	536.00
IUUC-Ete-032301	Echinops telfairi	68.39	4.00e-142	497.00
IUUC-Eca-033607	Equus caballus	90.02	0.00e+00	631.00
IUUC-Eeu-034888	Erinaceus europaeus	84.04	5.00e-128	451.00
IUUC-Fca-036075	Felis catus	89.53	0.00e+00	758.00
IUUC-Fal-037569	Ficedula albicollis	62.47	2.00e-118	419.00
IUUC-Gmo-038588	Gadus morhua	39.28	2.00e-70	259.00
IUUC-Gga-040777	Gallus gallus	60.81	8.00e-122	430.00
IUUC-Gac-042463	Gasterosteus aculeatus	41.63	3.00e-61	229.00
IUUC-Ggo-045269	Gorilla gorilla	85.60	0.00e+00	712.00
IUUC-Hsa-046249	Homo sapiens	85.60	0.00e+00	691.00
IUUC-Itr-048314	Ictidomys tridecemlineatus	86.80	0.00e+00	711.00
IUUC-Kpa-049392	Komagataella pastoris	36.05	2.00e-08	52.80
IUUC-Lch-049805	Latimeria chalumnae	50.85	4.00e-113	401.00
IUUC-Loc-052377	Lepisosteus oculatus	49.90	2.00e-95	342.00
IUUC-Mcc-055344	Macaca mulatta	84.77	0.00e+00	702.00
IUUC-Meu-055950	Macropus eugenii	63.60	2.00e-126	445.00
IUUC-Mla-059052	Melampsora laricipopulina	38.16	9.00e-11	60.10
IUUC-Mga-060049	Meleagris gallopavo	60.08	7.00e-121	427.00
IUUC-Mmr-061431	Microcebus murinus	86.96	0.00e+00	687.00
IUUC-Mdo-062016	Monodelphis domestica	69.91	4.00e-126	446.00
IUUC-Mmu-063235	Mus musculus	75.61	0.00e+00	646.00
IUUC-Mpu-066449	Mustela putorius furo	94.21	0.00e+00	800.00
IUUC-Mlu-067588	Myotis lucifugus	82.82	0.00e+00	656.00
IUUC-Nle-069192	Nomascus leucogenys	85.60	0.00e+00	709.00
IUUC-Opr-070300	Ochotona princeps	67.49	4.00e-151	528.00
IUUC-Ont-071998	Oreochromis niloticus	42.68	4.00e-65	242.00
IUUC-Oan-073610	Ornithorhynchus anatinus	65.65	2.00e-67	248.00
IUUC-Ocu-074603	Oryctolagus cuniculus	81.52	0.00e+00	655.00
IUUC-Ola-086681	Oryzias latipes	40.80	3.00e-72	266.00
IUUC-Oga-088183	Otolemur garnettii	87.24	0.00e+00	712.00
IUUC-Oar-090255	Ovis aries	87.28	4.00e-172	597.00
IUUC-Ptr-091029	Pan troglodytes	84.72	0.00e+00	647.00
IUUC-Pan-092241	Papio anubis	84.98	0.00e+00	707.00
IUUC-Psi-093506	Pelodiscus sinensis	63.24	2.00e-135	475.00
IUUC-Pma-094579	Petromyzon marinus	56.67	1.00e-26	114.00
IUUC-Pfo-097014	Poecilia formosa	42.58	2.00e-62	233.00
IUUC-Pab-098530	Pongo abelii	85.28	0.00e+00	661.00
IUUC-Pca-100939	Procavia capensis	66.67	1.00e-150	526.00
IUUC-Pva-103148	Pteropus vampyrus	81.93	0.00e+00	661.00
IUUC-Rno-105338	Rattus norvegicus	77.16	0.00e+00	668.00
IUUC-Sce-106282	Saccharomyces cerevisiae	35.96	2.00e-06	47.00
IUUC-Sha-107187	Sarcophilus harrisii	68.15	4.00e-108	384.00
IUUC-Sar-113356	Sorex araneus	69.53	8.00e-135	473.00
IUUC-Ssc-116290	Sus scrofa	88.41	0.00e+00	772.00
IUUC-Tru-117910	Takifugu rubripes	40.43	1.00e-61	230.00
IUUC-Tsy-119329	Tarsius syrichta	80.89	4.00e-168	583.00
IUUC-Tni-120521	Tetraodon nigroviridis	39.83	5.00e-63	234.00
IUUC-Tme-126989	Tuber melanosporum	32.76	8.00e-07	48.90
IUUC-Ttr-128997	Tursiops truncatus	83.11	0.00e+00	658.00
IUUC-Vpa-130154	Vicugna pacos	85.83	0.00e+00	725.00
IUUC-Xtr-132805	Xenopus tropicalis	50.21	1.00e-107	383.00
IUUC-Xma-133620	Xiphophorus maculatus	42.61	6.00e-61	228.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence