iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	Mentha
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	68.02	3.00e-68	258.00	IUUC-Hsa-045805

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MGHHLSKFSA RANSQEKRNP TASSSPREAA ALVETISLDE EELQVEEILT EATVSAATSP 60
AEVRQIIIKI QLAKMENGNP VAAGQVESFA EVVEQEEEQQ RQCADGATDD DAAALSADSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGTTGGCAGT CACACTGGAG AAACGGAACG AAGCGGACGC AGTGCGAACG ATACAGATAC 60
TTTTCGGGGA AGCGATACTT CTTCGGATTC GTGCGTGGTT TCGTTGCGTC GAGTGAAATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004860--F:protein kinase inhibitor activity
GO:0007298--P:border follicle cell migration
GO:0043697--P:cell dedifferentiation
GO:0048072--P:compound eye pigmentation
GO:0019221--P:cytokine-mediated signaling pathway
GO:0030718--P:germ-line stem cell population maintenance
GO:0007482--P:haltere development
GO:0008586--P:imaginal disc-derived wing vein morphogenesis
GO:0035556--P:intracellular signal transduction
GO:0007616--P:long-term memory
GO:0042059--P:negative regulation of epidermal growth factor receptor signaling pathway
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0045677--P:negative regulation of R7 cell differentiation
GO:0045873--P:negative regulation of sevenless signaling pathway
GO:0048802--P:notum morphogenesis
GO:0046425--P:regulation of JAK-STAT cascade

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001789	Ailuropoda melanoleuca	65.88	2.00e-68	251.00
IUUC-Apl-003815	Anas platyrhynchos	67.44	1.00e-70	259.00
IUUC-Aca-004504	Anolis carolinensis	67.24	4.00e-70	258.00
IUUC-Ame-010732	Astyanax mexicanus	70.18	2.00e-72	266.00
IUUC-Bta-012338	Bos taurus	67.24	2.00e-70	259.00
IUUC-Cja-019828	Callithrix jacchus	68.02	2.00e-70	258.00
IUUC-Cfa-020369	Canis familiaris	68.02	2.00e-70	259.00
IUUC-Cpo-021397	Cavia porcellus	68.02	2.00e-70	259.00
IUUC-Csa-023856	Chlorocebus sabaeus	68.02	2.00e-70	259.00
IUUC-Cho-024700	Choloepus hoffmanni	65.88	2.00e-68	252.00
IUUC-Dre-028262	Danio rerio	65.34	4.00e-71	261.00
IUUC-Dno-029019	Dasypus novemcinctus	68.02	1.00e-70	259.00
IUUC-Dor-030273	Dipodomys ordii	65.88	3.00e-68	251.00
IUUC-Ete-032972	Echinops telfairi	65.88	2.00e-68	251.00
IUUC-Eca-033867	Equus caballus	68.02	2.00e-70	259.00
IUUC-Eeu-035208	Erinaceus europaeus	65.88	7.00e-68	250.00
IUUC-Fca-035806	Felis catus	68.02	2.00e-70	259.00
IUUC-Fal-037117	Ficedula albicollis	67.44	2.00e-70	258.00
IUUC-Gmo-039066	Gadus morhua	65.17	2.00e-70	258.00
IUUC-Gga-040876	Gallus gallus	67.44	2.00e-70	259.00
IUUC-Gac-041931	Gasterosteus aculeatus	69.59	2.00e-72	265.00
IUUC-Ggo-045169	Gorilla gorilla	68.02	1.00e-70	259.00
IUUC-Hsa-045805	Homo sapiens	68.02	2.00e-70	259.00
IUUC-Itr-049048	Ictidomys tridecemlineatus	68.02	2.00e-70	259.00
IUUC-Lch-049686	Latimeria chalumnae	68.60	1.00e-71	263.00
IUUC-Loc-051791	Lepisosteus oculatus	70.18	2.00e-71	262.00
IUUC-Laf-054124	Loxodonta africana	68.02	1.00e-70	259.00
IUUC-Mcc-055175	Macaca mulatta	68.02	2.00e-70	259.00
IUUC-Meu-056557	Macropus eugenii	67.44	2.00e-70	259.00
IUUC-Mga-059214	Meleagris gallopavo	67.44	1.00e-70	259.00
IUUC-Mvi-060418	Microbotryum violaceum	30.26	8.30e-01	26.20
IUUC-Mmr-060613	Microcebus murinus	68.02	2.00e-70	259.00
IUUC-Mdo-062788	Monodelphis domestica	67.44	3.00e-70	258.00
IUUC-Mmu-064333	Mus musculus	67.24	2.00e-70	259.00
IUUC-Mpu-066048	Mustela putorius furo	68.02	2.00e-70	259.00
IUUC-Mlu-067430	Myotis lucifugus	68.02	2.00e-70	259.00
IUUC-Nle-069086	Nomascus leucogenys	68.02	2.00e-70	259.00
IUUC-Opr-070312	Ochotona princeps	67.24	2.00e-70	259.00
IUUC-Ont-072537	Oreochromis niloticus	70.76	9.00e-74	270.00
IUUC-Ocu-074123	Oryctolagus cuniculus	67.24	1.00e-70	259.00
IUUC-Ola-086934	Oryzias latipes	66.86	1.00e-70	259.00
IUUC-Oga-088535	Otolemur garnettii	68.02	2.00e-70	259.00
IUUC-Oar-089875	Ovis aries	67.24	2.00e-70	259.00
IUUC-Ptr-090541	Pan troglodytes	68.02	2.00e-70	259.00
IUUC-Pan-092416	Papio anubis	68.02	2.00e-70	259.00
IUUC-Psi-092960	Pelodiscus sinensis	68.02	1.00e-70	259.00
IUUC-Pma-094222	Petromyzon marinus	68.42	9.00e-73	266.00
IUUC-Pfo-097139	Poecilia formosa	70.76	1.00e-72	266.00
IUUC-Pab-098659	Pongo abelii	68.02	2.00e-70	259.00
IUUC-Pop-098820	Populus trichocarpa	32.50	1.50e-01	30.00
IUUC-Pca-100222	Procavia capensis	67.44	2.00e-70	258.00
IUUC-Pva-102387	Pteropus vampyrus	68.02	2.00e-70	258.00
IUUC-Rno-105698	Rattus norvegicus	67.24	2.00e-70	259.00
IUUC-Sha-107234	Sarcophilus harrisii	67.44	3.00e-70	258.00
IUUC-Sar-113698	Sorex araneus	67.24	3.00e-70	258.00
IUUC-Ssc-115985	Sus scrofa	68.02	1.00e-70	259.00
IUUC-Tgu-116676	Taeniopygia guttata	67.44	2.00e-70	259.00
IUUC-Tru-117781	Takifugu rubripes	62.50	7.00e-52	196.00
IUUC-Tsy-118979	Tarsius syrichta	65.88	5.00e-68	249.00
IUUC-Tni-120436	Tetraodon nigroviridis	65.73	1.00e-71	263.00
IUUC-Tbe-127353	Tupaia belangeri	68.02	2.00e-70	259.00
IUUC-Ttr-128907	Tursiops truncatus	68.02	2.00e-70	258.00
IUUC-Vda-129974	Verticillium dahliae	28.24	7.70e-02	32.00
IUUC-Vpa-130140	Vicugna pacos	68.02	2.00e-70	259.00
IUUC-Vvi-131327	Vitis vinifera	25.42	1.40e-01	30.00
IUUC-Xtr-132817	Xenopus tropicalis	66.86	1.00e-70	259.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence