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Basic Information Integrated Annotations

Tag Content
iUUCD ID IUUC-Mmu-063244
UUCD1 version UUC-MuM-00047
Ensembl Protein ID ENSMUSP00000022681.4
UniProt Accession Q8R1G6; PDLI2_MOUSE
Genbank Protein ID AAH24556.1
Protein Name PDZ and LIM domain protein 2; PDZ-LIM protein mystique
Genbank Nucleotide ID BC024556
Gene Name Pdlim2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000022090.10 ENSMUST00000022681.10 ENSMUSP00000022681.4
ENSMUSG00000022090.10 ENSMUST00000125300.2 ENSMUSP00000116694.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IIDiRefIndexHINTMentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTMUniProt
PHOSIDA
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
E3 activity/Other E3 activity/Other 15963787
Reviewed
Classification
Family Identity E-value Score Source Orthology
E3 activity/Other 72.88 8.00e-124 441.00 IUUC-Hsa-045868
Organism Mus musculus
Functional Description
(View)

Functional Description



     Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity (By similarity).
Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity (By similarity).
Protein Sequence
(Fasta)
MALTVDVAGP APWGFRISGG RDFHTPIIVT KVTERGKAEA ADLRPGDIIV AINGQSAENM 60
LHAEAQSKIR QSASPLRLQL DRSQTASPGQ TNGEGSLEVL ATRFQGSLRT HRDSQSSQRS 120
It may take some time, please wait.

Protein Fasta Sequence



>IUUC-Mmu-063244|E3,E3 activity/Other|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAGTTGTAAG AGCAACTGAA GAGGCAGGAG GCAGCTGCGT GGGCTCTCAA CTCCCCAGGG 60
CAAGAGTTGC CAGGTATAGC TCTGGGGGAC CCTCTGGTCA GATGGCTCCT CCTTCCTGGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Mmu-063244|E3,E3 activity/Other|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0440--LIM domain
KW-0479--Metal-binding
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031847--DUF4749
IPR001478--PDZ
IPR001781--Znf_LIM

PROSITE

PS00478--LIM_DOMAIN_1
PS50023--LIM_DOMAIN_2
PS50106--PDZ

Pfam

PF15936--DUF4749
PF00412--LIM
PF00595--PDZ

SMART

SM00132--LIM
SM00228--PDZ

Gene Ontology

GO:0030864--C:cortical actin cytoskeleton
GO:0070062--C:extracellular exosome
GO:0001725--C:stress fiber
GO:0008270--F:zinc ion binding

KEGG mmu:213019
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001484 Ailuropoda melanoleuca 75.21 2.00e-123 435.00
IUUC-Aca-004512 Anolis carolinensis 55.75 8.00e-91 327.00
IUUC-Ame-011626 Astyanax mexicanus 44.90 1.00e-75 276.00
IUUC-Bta-012510 Bos taurus 73.74 2.00e-120 425.00
IUUC-Bdi-014056 Brachypodium distachyon 31.75 9.00e-03 35.40
IUUC-Cja-019248 Callithrix jacchus 72.47 6.00e-124 437.00
IUUC-Cfa-020352 Canis familiaris 73.88 6.00e-121 427.00
IUUC-Cpo-021995 Cavia porcellus 68.64 8.00e-111 393.00
IUUC-Csa-024190 Chlorocebus sabaeus 76.84 2.00e-120 425.00
IUUC-Dre-027418 Danio rerio 43.94 6.00e-69 254.00
IUUC-Dor-030439 Dipodomys ordii 63.79 1.00e-61 230.00
IUUC-Dme-031753 Drosophila melanogaster 36.84 2.00e-10 60.10
IUUC-Eca-034183 Equus caballus 75.00 3.00e-120 424.00
IUUC-Eeu-034958 Erinaceus europaeus 72.95 3.00e-89 321.00
IUUC-Fca-035680 Felis catus 76.97 9.00e-124 436.00
IUUC-Fal-037626 Ficedula albicollis 33.82 2.00e-07 51.60
IUUC-Gmo-038558 Gadus morhua 52.55 5.00e-39 155.00
IUUC-Gac-041738 Gasterosteus aculeatus 45.22 6.00e-78 284.00
IUUC-Ggo-044609 Gorilla gorilla 74.01 1.00e-120 426.00
IUUC-Hsa-045868 Homo sapiens 74.52 1.00e-118 420.00
IUUC-Itr-048876 Ictidomys tridecemlineatus 79.78 3.00e-125 441.00
IUUC-Loc-052212 Lepisosteus oculatus 48.07 1.00e-78 286.00
IUUC-Laf-053824 Loxodonta africana 78.29 1.00e-119 422.00
IUUC-Mcc-054962 Macaca mulatta 76.84 2.00e-120 425.00
IUUC-Meu-056007 Macropus eugenii 74.74 2.00e-39 157.00
IUUC-Mmr-060607 Microcebus murinus 77.12 2.00e-120 425.00
IUUC-Mdo-062935 Monodelphis domestica 72.52 3.00e-52 198.00
IUUC-Mpu-065888 Mustela putorius furo 76.55 8.00e-113 400.00
IUUC-Mlu-067124 Myotis lucifugus 76.69 1.00e-131 462.00
IUUC-Ncr-068674 Neurospora crassa 40.35 5.00e-07 50.40
IUUC-Nle-069063 Nomascus leucogenys 73.65 7.00e-84 303.00
IUUC-Opr-071221 Ochotona princeps 71.55 3.00e-100 358.00
IUUC-Ont-072000 Oreochromis niloticus 44.38 4.00e-74 271.00
IUUC-Oan-073012 Ornithorhynchus anatinus 54.55 3.00e-84 305.00
IUUC-Ocu-074376 Oryctolagus cuniculus 75.14 4.00e-113 400.00
IUUC-Ola-086915 Oryzias latipes 45.66 1.00e-76 279.00
IUUC-Oga-088393 Otolemur garnettii 77.31 1.00e-125 442.00
IUUC-Oar-089421 Ovis aries 73.18 7.00e-123 433.00
IUUC-Ptr-091089 Pan troglodytes 75.99 4.00e-106 377.00
IUUC-Pan-092163 Papio anubis 76.84 3.00e-115 408.00
IUUC-Psi-093043 Pelodiscus sinensis 44.80 4.00e-68 251.00
IUUC-Pfo-096885 Poecilia formosa 52.55 4.00e-39 155.00
IUUC-Pab-097988 Pongo abelii 76.29 4.00e-106 377.00
IUUC-Pca-100131 Procavia capensis 77.84 2.00e-114 406.00
IUUC-Pva-102706 Pteropus vampyrus 70.79 2.00e-119 422.00
IUUC-Ptt-104003 Puccinia triticina 34.69 3.90e-01 29.60
IUUC-Pte-104256 Pyrenophora teres 35.19 1.00e-05 45.10
IUUC-Pyt-104720 Pyrenophora triticirepentis 35.19 3.00e-05 42.70
IUUC-Rno-104992 Rattus norvegicus 93.41 5.00e-164 570.00
IUUC-Sha-107463 Sarcophilus harrisii 60.22 6.00e-68 250.00
IUUC-Sar-113038 Sorex araneus 40.66 7.00e-18 85.90
IUUC-Ssc-115811 Sus scrofa 74.37 2.00e-119 422.00
IUUC-Tae-123985 Triticum aestivum 33.33 4.40e-02 32.00
IUUC-Tbe-127240 Tupaia belangeri 63.93 1.00e-71 263.00
IUUC-Ttr-128236 Tursiops truncatus 59.32 1.00e-87 317.00
IUUC-Vpa-130569 Vicugna pacos 50.84 2.00e-76 279.00
Created Date 25-Jun-2017

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