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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Hsa-045985
UUCD1 version UUC-HoS-00782
Ensembl Protein ID ENSP00000215739.8
UniProt Accession Q8N653; Q14776; Q20WK0; LZTR1_HUMAN
Genbank Protein ID CAJ86451.1; EAX02923.1; AAH26214.2; BAA07508.1
Protein Name Leucine-zipper-like transcriptional regulator 1
Genbank Nucleotide ID CT841521; CH471176; BC026214; D38496
Gene Name LZTR1; TCFL2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000099949.18 ENST00000215739.12 ENSP00000215739.8
ENSG00000099949.18 ENST00000414985.5 ENSP00000397247.1
ENSG00000099949.18 ENST00000443265.5 ENSP00000406466.1
ENSG00000099949.18 ENST00000415354.6 ENSP00000393765.2
ENSG00000099949.18 ENST00000439171.5 ENSP00000390836.1
ENSG00000099949.18 ENST00000452988.5 ENSP00000408789.1
ENSG00000099949.18 ENST00000415817.1 ENSP00000397252.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACTargetScan
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
ClinVarGWASdbOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
UniProtBioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 1.10e-20 75.4 667 735
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd..vqpevfrallkFlYtgklden 68
           +D++l ++g   +ahk++Laa+Ss+F+a+f + ++e   +  + i +   + ++f+ +l+++Y g+++++
   Q: 667  CDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDG-QVNISIGEmvPSRQAFESMLRYIYYGEVNMP 735
           8**********************************987.7888888888999**************9876 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MAGPGSTGGQ IGAAALAGGA RSKVAPSVDF DHSCSDSVEY LTLNFGPFET VHRWRRLPPC 60
DEFVGARRSK HTVVAYKDAI YVFGGDNGKT MLNDLLRFDV KDCSWCRAFT TGTPPAPRYH 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045985|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGACCGCAC TAGGAAGAGG CCGGTAAGAA CTCGCTGGCG GCAAGGCTAC GAACTACCTA 60
AAAGGACGTA TGGAGCAGGG CCTGGGCGGG GTTAGGAGGG GATCCTGTGA CGTCTCGTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045985|E3,BTB_Other|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-0225--Disease mutation
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011498--Kelch_2
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF00651--BTB
PF01344--Kelch_1
PF07646--Kelch_2
SMART

SM00225--BTB
SM00612--Kelch
Gene Ontology

GO:0005794--C:Golgi apparatus
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0009653--P:anatomical structure morphogenesis
KEGG hsa:8216
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001645 Ailuropoda melanoleuca 96.95 0.00e+00 1561.00
IUUC-Apl-003187 Anas platyrhynchos 87.24 0.00e+00 1282.00
IUUC-Aca-005240 Anolis carolinensis 83.78 0.00e+00 1419.00
IUUC-Ame-010863 Astyanax mexicanus 78.05 0.00e+00 1000.00
IUUC-Bgr-012217 Blumeria graminis 29.81 1.00e-15 78.60
IUUC-Bta-012889 Bos taurus 93.79 0.00e+00 1545.00
IUUC-Cfa-020575 Canis familiaris 95.98 0.00e+00 1583.00
IUUC-Cpo-021855 Cavia porcellus 97.44 0.00e+00 1659.00
IUUC-Csa-023483 Chlorocebus sabaeus 97.93 0.00e+00 1664.00
IUUC-Cgl-026387 Colletotrichum gloeosporioides 31.06 9.00e-16 79.00
IUUC-Dre-027795 Danio rerio 82.13 0.00e+00 1387.00
IUUC-Dno-029959 Dasypus novemcinctus 96.59 0.00e+00 1592.00
IUUC-Dor-030779 Dipodomys ordii 93.78 0.00e+00 1578.00
IUUC-Dme-031621 Drosophila melanogaster 52.39 0.00e+00 815.00
IUUC-Ete-032307 Echinops telfairi 92.44 0.00e+00 1513.00
IUUC-Eca-034178 Equus caballus 95.48 0.00e+00 1420.00
IUUC-Eeu-034815 Erinaceus europaeus 91.34 0.00e+00 1498.00
IUUC-Fca-036259 Felis catus 95.76 0.00e+00 1537.00
IUUC-Fal-037201 Ficedula albicollis 84.40 0.00e+00 1404.00
IUUC-Gmo-039641 Gadus morhua 80.02 0.00e+00 1320.00
IUUC-Ggr-039868 Gaeumannomyces graminis 33.10 1.00e-14 75.90
IUUC-Gga-041236 Gallus gallus 78.49 0.00e+00 855.00
IUUC-Gac-042539 Gasterosteus aculeatus 81.74 0.00e+00 1363.00
IUUC-Gma-044305 Glycine max 26.97 3.00e-09 57.00
IUUC-Ggo-044796 Gorilla gorilla 99.17 0.00e+00 1650.00
IUUC-Itr-048271 Ictidomys tridecemlineatus 96.34 0.00e+00 1613.00
IUUC-Lch-049842 Latimeria chalumnae 83.66 0.00e+00 1401.00
IUUC-Loc-052639 Lepisosteus oculatus 84.40 0.00e+00 1425.00
IUUC-Laf-054178 Loxodonta africana 96.47 0.00e+00 1601.00
IUUC-Mcc-055897 Macaca mulatta 93.69 0.00e+00 1566.00
IUUC-Meu-055973 Macropus eugenii 85.40 0.00e+00 1409.00
IUUC-Mga-059441 Meleagris gallopavo 84.43 0.00e+00 1303.00
IUUC-Mmr-061048 Microcebus murinus 95.62 0.00e+00 1588.00
IUUC-Mdo-062170 Monodelphis domestica 83.42 0.00e+00 1360.00
IUUC-Mmu-063890 Mus musculus 96.10 0.00e+00 1595.00
IUUC-Mpu-066468 Mustela putorius furo 97.44 0.00e+00 1612.00
IUUC-Mlu-068212 Myotis lucifugus 96.71 0.00e+00 1579.00
IUUC-Nle-070128 Nomascus leucogenys 97.61 0.00e+00 1654.00
IUUC-Ont-072422 Oreochromis niloticus 83.64 0.00e+00 1407.00
IUUC-Oan-073403 Ornithorhynchus anatinus 88.24 7.00e-59 219.00
IUUC-Ocu-073745 Oryctolagus cuniculus 96.49 0.00e+00 1596.00
IUUC-Osa-085827 Oryza sativa 29.05 6.00e-10 59.30
IUUC-Ola-087296 Oryzias latipes 81.77 0.00e+00 1373.00
IUUC-Oga-088787 Otolemur garnettii 94.40 0.00e+00 1573.00
IUUC-Ptr-090622 Pan troglodytes 99.88 0.00e+00 1671.00
IUUC-Pan-091982 Papio anubis 98.18 0.00e+00 1665.00
IUUC-Psi-093764 Pelodiscus sinensis 86.82 0.00e+00 1334.00
IUUC-Pma-094632 Petromyzon marinus 75.43 0.00e+00 706.00
IUUC-Pfo-096914 Poecilia formosa 81.50 0.00e+00 1365.00
IUUC-Pab-098648 Pongo abelii 96.90 0.00e+00 1635.00
IUUC-Pop-099596 Populus trichocarpa 25.86 2.00e-10 60.80
IUUC-Pca-100970 Procavia capensis 91.83 0.00e+00 1528.00
IUUC-Ppe-101872 Prunus persica 27.17 6.00e-10 59.30
IUUC-Pva-103195 Pteropus vampyrus 97.20 0.00e+00 1598.00
IUUC-Rno-105266 Rattus norvegicus 96.09 0.00e+00 1586.00
IUUC-Ssc-115775 Sus scrofa 95.86 0.00e+00 1570.00
IUUC-Tgu-117360 Taeniopygia guttata 87.80 0.00e+00 1468.00
IUUC-Tru-118151 Takifugu rubripes 84.10 0.00e+00 1396.00
IUUC-Tni-119806 Tetraodon nigroviridis 83.89 0.00e+00 1400.00
IUUC-Tca-120928 Theobroma cacao 26.97 3.00e-09 57.00
IUUC-Tbe-127786 Tupaia belangeri 96.23 0.00e+00 1001.00
IUUC-Ttr-128653 Tursiops truncatus 96.10 0.00e+00 1560.00
IUUC-Vda-129868 Verticillium dahliae 28.75 2.00e-14 74.70
IUUC-Vvi-131645 Vitis vinifera 26.97 5.00e-09 56.20
IUUC-Xtr-132600 Xenopus tropicalis 76.63 0.00e+00 1261.00
Created Date 25-Jun-2017

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