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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-045725
Ensembl Protein ID ENSP00000294507.3
UniProt Accession Q13571; Q13240; Q14698; Q3KP54; LAPM5_HUMAN
Genbank Protein ID AAB08975.1; AAA74018.1; BAA07643.1; AAI06897.1
Protein Name Lysosomal-associated transmembrane protein 5; Lysosomal-associated multitransmembrane protein 5; Retinoic acid-inducible E3 protein
Genbank Nucleotide ID U51240; U30498; D42042; BC106896
Gene Name LAPTM5; KIAA0085
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000162511.7 ENST00000294507.3 ENSP00000294507.3
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBaseCircNet
miRTarBasemicroRNATRANSFACmiRWalk
TargetScanRepTarSomamiRmiRcode
RAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
GWASdbGWAS CentralOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDBioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/UIM 77.86 1.00e-106 383.00 IUUC-Mmu-064111
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Homo sapiens
Functional Description
(View)

Functional Description


     May have a special functional role during embryogenesis and in adult hematopoietic cells.
 May have a special functional role during embryogenesis and in adult hematopoietic cells.
Protein Sequence
(Fasta)
MDPRLSTVRQ TCCCFNVRIA TTALAIYHVI MSVLLFIEHS VEVAHGKASC KLSQMGYLRI 60
ADLISSFLLI TMLFIISLSL LIGVVKNREK YLLPFLSLQI MDYLLCLLTL LGSYIELPAY 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045725|UBD,UIM|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CTTCCCCTTC TCTGCCCTGC TCCAGGCACC AGGCTCTTTC CCCTTCAGTG TCTCAGAGGA 60
GGGGACGGCA GCACCATGGA CCCCCGCTTG TCCACTGTCC GCCAGACCTG CTGCTGCTTC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045725|UBD,UIM|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0458--Lysosome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0621--Polymorphism
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0813--Transport
Interpro

IPR004687--LAPTM4/5
IPR018396--LAPTM_4A/5
IPR018397--Lysosomal-assoc_TM_prot5
Pfam

PF03821--Mtp
Gene Ontology

GO:0005887--C:integral component of plasma membrane
GO:0005765--C:lysosomal membrane
GO:0005764--C:lysosome
GO:0006810--P:transport
KEGG hsa:7805
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002045 Ailuropoda melanoleuca 81.68 1.00e-117 415.00
IUUC-Apl-003791 Anas platyrhynchos 56.22 5.00e-63 234.00
IUUC-Bta-013477 Bos taurus 86.74 3.00e-115 407.00
IUUC-Cja-019476 Callithrix jacchus 93.13 8.00e-132 462.00
IUUC-Cfa-021270 Canis familiaris 84.79 2.00e-108 385.00
IUUC-Cpo-021959 Cavia porcellus 79.55 1.00e-102 365.00
IUUC-Csa-023290 Chlorocebus sabaeus 93.51 7.00e-134 469.00
IUUC-Dno-029099 Dasypus novemcinctus 83.21 9.00e-121 426.00
IUUC-Dor-030794 Dipodomys ordii 77.10 7.00e-92 330.00
IUUC-Ete-032961 Echinops telfairi 71.24 4.00e-83 300.00
IUUC-Eca-033510 Equus caballus 87.21 9.00e-122 429.00
IUUC-Eeu-034658 Erinaceus europaeus 84.05 2.00e-109 387.00
IUUC-Fca-036133 Felis catus 84.41 2.00e-121 427.00
IUUC-Fal-036847 Ficedula albicollis 50.19 9.00e-57 213.00
IUUC-Gga-040267 Gallus gallus 54.37 4.00e-71 261.00
IUUC-Ggo-045536 Gorilla gorilla 98.85 8.00e-141 492.00
IUUC-Itr-048309 Ictidomys tridecemlineatus 67.30 1.00e-86 313.00
IUUC-Lch-050140 Latimeria chalumnae 37.50 6.00e-28 117.00
IUUC-Loc-052067 Lepisosteus oculatus 31.93 4.00e-11 61.60
IUUC-Laf-053429 Loxodonta africana 78.87 3.00e-99 354.00
IUUC-Mcc-054614 Macaca mulatta 94.66 1.00e-135 475.00
IUUC-Meu-056154 Macropus eugenii 71.10 2.00e-96 345.00
IUUC-Mga-059988 Meleagris gallopavo 53.52 6.00e-72 263.00
IUUC-Mmr-061540 Microcebus murinus 85.50 6.00e-116 409.00
IUUC-Mdo-062233 Monodelphis domestica 70.83 1.00e-97 349.00
IUUC-Mmu-064111 Mus musculus 78.24 2.00e-110 391.00
IUUC-Mpu-066426 Mustela putorius furo 81.37 3.00e-116 410.00
IUUC-Mlu-066997 Myotis lucifugus 83.61 2.00e-106 378.00
IUUC-Nle-069725 Nomascus leucogenys 96.95 5.00e-139 486.00
IUUC-Opr-070198 Ochotona princeps 84.56 2.00e-97 348.00
IUUC-Oan-073370 Ornithorhynchus anatinus 61.11 2.00e-70 258.00
IUUC-Ocu-074337 Oryctolagus cuniculus 84.90 1.00e-110 392.00
IUUC-Oga-088795 Otolemur garnettii 86.31 9.00e-119 419.00
IUUC-Oar-089326 Ovis aries 86.74 5.00e-125 440.00
IUUC-Ptr-090612 Pan troglodytes 98.77 6.00e-125 440.00
IUUC-Pan-091790 Papio anubis 94.27 8.00e-135 472.00
IUUC-Psi-093316 Pelodiscus sinensis 52.78 9.00e-68 249.00
IUUC-Pab-097954 Pongo abelii 98.09 1.00e-139 488.00
IUUC-Pca-100283 Procavia capensis 86.64 3.00e-112 397.00
IUUC-Pva-102601 Pteropus vampyrus 67.18 3.00e-86 311.00
IUUC-Rno-105182 Rattus norvegicus 79.01 1.00e-103 369.00
IUUC-Sha-107231 Sarcophilus harrisii 71.21 2.00e-91 328.00
IUUC-Ssc-115840 Sus scrofa 85.94 1.00e-114 405.00
IUUC-Tgu-117333 Taeniopygia guttata 55.70 7.00e-72 263.00
IUUC-Tsy-119025 Tarsius syrichta 56.65 2.00e-61 229.00
IUUC-Tbe-128046 Tupaia belangeri 71.37 2.00e-100 358.00
IUUC-Ttr-129234 Tursiops truncatus 86.36 3.00e-124 437.00
Created Date 25-Jun-2017

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