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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Sce-106356
UUCD1 version UUC-SaC-00183
Ensembl Protein ID YDR128W
UniProt Accession Q03897; D6VSB4; WDR59_YEAST
Genbank Protein ID CAA88209.1; DAA11974.1
Protein Name Maintenance of telomere capping protein 5; SEH-associated protein 3
Genbank Nucleotide ID Z48179; BK006938
Gene Name MTC5; SEA3; YDR128W
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YDR128W YDR128W YDR128W
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFdbPTMUniProt
BioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.70e-12 45.6 199 231
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.....sdtllvsGsdDgtikvWDl 30
           gH +sv++++f     s   + s+s+Dgt+k WD+
   Q: 199  GHVSSVNSIDFnrfkyS--EIMSSSNDGTVKFWDY 231
           8**********765332..6**************7 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis. May be involved in telomere capping.
 Component of the SEA complex which coats the vacuolar membrane and is involved in intracellular trafficking, autophagy, response to nitrogen starvation, and amino acid biogenesis. May be involved in telomere capping.
Protein Sequence
(Fasta)
MCSSINEGPY NSPTFGKSLS LKVDGGFNAV SINPSGRDIV LASRQGLYII DLDDPFTPPR 60
WLHHITPWQV ADVQWSPHPA KPYWIVSTSN QKAIIWNLAK SSSNAIEFVL HGHSRAITDI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106356|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTGCAGTA GTATAAATGA AGGTCCGTAT AATTCGCCCA CTTTTGGAAA ATCATTATCG 60
TTGAAAGTAG ATGGTGGGTT CAATGCCGTA TCTATCAATC CCTCTGGTAG GGATATTGTT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106356|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0597--Phosphoprotein
KW-0653--Protein transport
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0926--Vacuole
KW-0853--WD repeat
Interpro

IPR025651--Mtc5
IPR006575--RWD-domain
IPR016135--UBQ-conjugating_enzyme/RWD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50908--RWD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
SMART

SM00591--RWD
SM00320--WD40
Gene Ontology

GO:0097042--C:extrinsic component of fungal-type vacuolar membrane
GO:0035859--C:Seh1-associated complex
GO:1904263--P:positive regulation of TORC1 signaling
GO:0015031--P:protein transport
KEGG sce:YDR128W
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002149 Ailuropoda melanoleuca 28.32 1.00e-59 223.00
IUUC-Apl-004021 Anas platyrhynchos 29.01 3.00e-57 214.00
IUUC-Aca-004977 Anolis carolinensis 28.12 1.00e-57 216.00
IUUC-Ago-007961 Ashbya gossypii 48.16 0.00e+00 1069.00
IUUC-Acl-008161 Aspergillus clavatus 36.12 1.00e-122 432.00
IUUC-Afl-008686 Aspergillus flavus 35.96 2.00e-123 435.00
IUUC-Afu-008932 Aspergillus fumigatus 36.85 1.00e-122 432.00
IUUC-Ani-009493 Aspergillus nidulans 35.51 9.00e-119 419.00
IUUC-Ang-009876 Aspergillus niger 37.58 4.00e-127 447.00
IUUC-Aor-009926 Aspergillus oryzae 35.96 2.00e-123 435.00
IUUC-Ate-010274 Aspergillus terreus 35.94 2.00e-122 432.00
IUUC-Ame-011297 Astyanax mexicanus 32.27 9.00e-49 186.00
IUUC-Bgr-012173 Blumeria graminis 31.33 2.00e-98 352.00
IUUC-Bta-013261 Bos taurus 28.13 4.00e-59 221.00
IUUC-Bci-013971 Botrytis cinerea 33.89 2.00e-97 348.00
IUUC-Cja-019167 Callithrix jacchus 27.75 7.00e-58 217.00
IUUC-Cfa-020287 Canis familiaris 27.94 2.00e-57 215.00
IUUC-Cpo-022510 Cavia porcellus 27.48 1.00e-52 199.00
IUUC-Csa-023474 Chlorocebus sabaeus 28.32 5.00e-59 221.00
IUUC-Cho-024634 Choloepus hoffmanni 34.78 2.00e-51 196.00
IUUC-Cin-025642 Ciona intestinalis 28.68 8.00e-55 206.00
IUUC-Csv-025848 Ciona savignyi 33.01 5.00e-33 132.00
IUUC-Cgl-026531 Colletotrichum gloeosporioides 31.87 1.00e-99 355.00
IUUC-Cne-027088 Cryptococcus neoformans 31.87 2.00e-84 305.00
IUUC-Dre-028753 Danio rerio 26.64 3.00e-50 191.00
IUUC-Dno-029733 Dasypus novemcinctus 28.38 2.00e-57 216.00
IUUC-Dor-030781 Dipodomys ordii 29.47 3.00e-39 155.00
IUUC-Dme-031803 Drosophila melanogaster 27.13 2.00e-48 185.00
IUUC-Ete-032622 Echinops telfairi 24.25 6.00e-38 150.00
IUUC-Eca-033344 Equus caballus 28.71 2.00e-59 221.00
IUUC-Eeu-034523 Erinaceus europaeus 34.29 2.00e-53 202.00
IUUC-Fca-035650 Felis catus 28.13 9.00e-59 220.00
IUUC-Fal-037404 Ficedula albicollis 28.99 6.00e-60 223.00
IUUC-Fox-037955 Fusarium oxysporum 33.84 2.00e-89 322.00
IUUC-Fso-038289 Fusarium solani 34.60 3.00e-94 338.00
IUUC-Gmo-038547 Gadus morhua 27.33 1.00e-51 196.00
IUUC-Ggr-039858 Gaeumannomyces graminis 30.63 5.00e-83 301.00
IUUC-Gga-041030 Gallus gallus 28.52 5.00e-58 217.00
IUUC-Gac-042581 Gasterosteus aculeatus 27.94 3.00e-56 211.00
IUUC-Ggo-044641 Gorilla gorilla 28.32 3.00e-59 221.00
IUUC-Hsa-046134 Homo sapiens 28.13 2.00e-58 218.00
IUUC-Itr-048551 Ictidomys tridecemlineatus 34.29 8.00e-54 202.00
IUUC-Kpa-049091 Komagataella pastoris 35.27 0.00e+00 708.00
IUUC-Lch-050288 Latimeria chalumnae 32.51 3.00e-50 191.00
IUUC-Loc-052802 Lepisosteus oculatus 27.67 6.00e-52 197.00
IUUC-Lma-053296 Leptosphaeria maculans 32.81 6.00e-89 320.00
IUUC-Laf-053997 Loxodonta africana 28.52 1.00e-58 219.00
IUUC-Mcc-055855 Macaca mulatta 28.32 5.00e-59 220.00
IUUC-Meu-056898 Macropus eugenii 32.33 2.00e-19 89.40
IUUC-Mor-056913 Magnaporthe oryzae 32.66 1.00e-81 296.00
IUUC-Mpo-057612 Magnaporthe poae 32.44 3.00e-83 301.00
IUUC-Mla-059097 Melampsora laricipopulina 37.79 1.00e-69 256.00
IUUC-Mga-059218 Meleagris gallopavo 28.60 1.00e-57 216.00
IUUC-Mvi-060251 Microbotryum violaceum 40.76 4.00e-82 298.00
IUUC-Mmr-061093 Microcebus murinus 26.60 6.00e-50 190.00
IUUC-Mdo-062757 Monodelphis domestica 27.38 2.00e-56 212.00
IUUC-Mmu-063839 Mus musculus 27.78 8.00e-57 213.00
IUUC-Mpu-065977 Mustela putorius furo 28.32 2.00e-58 219.00
IUUC-Mlu-067460 Myotis lucifugus 28.32 1.00e-57 216.00
IUUC-Nfi-068250 Neosartorya fischeri 36.27 3.00e-123 434.00
IUUC-Ncr-068710 Neurospora crassa 32.18 1.00e-95 343.00
IUUC-Nle-070011 Nomascus leucogenys 28.13 1.00e-58 219.00
IUUC-Opr-070731 Ochotona princeps 33.68 3.00e-48 185.00
IUUC-Ont-072165 Oreochromis niloticus 26.60 8.00e-51 193.00
IUUC-Oan-072887 Ornithorhynchus anatinus 28.18 7.00e-56 210.00
IUUC-Ocu-073926 Oryctolagus cuniculus 27.94 4.00e-58 218.00
IUUC-Ola-087111 Oryzias latipes 25.73 1.00e-46 179.00
IUUC-Oga-088850 Otolemur garnettii 27.75 9.00e-59 219.00
IUUC-Oar-090291 Ovis aries 28.32 8.00e-59 220.00
IUUC-Ptr-091044 Pan troglodytes 28.71 1.00e-58 219.00
IUUC-Pan-092374 Papio anubis 28.32 3.00e-59 221.00
IUUC-Pma-094544 Petromyzon marinus 26.22 2.00e-48 184.00
IUUC-Pno-095068 Phaeosphaeria nodorum 31.53 1.00e-87 316.00
IUUC-Pfo-096480 Poecilia formosa 26.75 2.00e-50 192.00
IUUC-Pab-098134 Pongo abelii 27.94 5.00e-56 211.00
IUUC-Pca-100763 Procavia capensis 26.65 2.00e-30 126.00
IUUC-Pva-102544 Pteropus vampyrus 27.75 2.00e-57 215.00
IUUC-Pgr-103257 Puccinia graminis 38.40 4.00e-76 278.00
IUUC-Ptt-103942 Puccinia triticina 37.93 2.00e-72 265.00
IUUC-Pte-104065 Pyrenophora teres 31.80 4.00e-88 318.00
IUUC-Rno-105468 Rattus norvegicus 28.52 4.00e-57 214.00
IUUC-Sha-106662 Sarcophilus harrisii 28.57 3.00e-55 208.00
IUUC-Sja-107973 Schizosaccharomyces japonicus 40.61 1.00e-119 422.00
IUUC-Spo-108265 Schizosaccharomyces pombe 36.91 2.00e-122 431.00
IUUC-Ssl-108662 Sclerotinia sclerotiorum 34.72 1.00e-101 363.00
IUUC-Sar-113525 Sorex araneus 22.86 3.00e-14 72.40
IUUC-Sre-115163 Sporisorium reilianum 37.24 8.00e-52 197.00
IUUC-Ssc-116234 Sus scrofa 34.48 8.00e-54 201.00
IUUC-Tgu-116525 Taeniopygia guttata 28.71 2.00e-59 222.00
IUUC-Tru-118432 Takifugu rubripes 27.24 2.00e-52 199.00
IUUC-Tsy-119306 Tarsius syrichta 29.89 9.00e-36 143.00
IUUC-Tni-120757 Tetraodon nigroviridis 25.92 2.00e-49 189.00
IUUC-Tre-122187 Trichoderma reesei 31.51 9.00e-96 343.00
IUUC-Tvi-122367 Trichoderma virens 32.33 4.00e-97 348.00
IUUC-Tme-126986 Tuber melanosporum 35.74 4.00e-114 404.00
IUUC-Tbe-127800 Tupaia belangeri 25.00 7.00e-26 110.00
IUUC-Ttr-129154 Tursiops truncatus 27.64 9.00e-52 196.00
IUUC-Uma-129366 Ustilago maydis 36.68 5.00e-49 188.00
IUUC-Vda-129827 Verticillium dahliae 31.47 2.00e-96 345.00
IUUC-Vpa-130493 Vicugna pacos 28.54 1.00e-56 212.00
IUUC-Xtr-131941 Xenopus tropicalis 28.10 7.00e-56 210.00
IUUC-Xma-133903 Xiphophorus maculatus 32.92 4.00e-52 197.00
Created Date 25-Jun-2017

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