iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.20e-19	70.2	915	985

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 2    vpeeflCpIslelMrdPvvlp.sGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceen 72
            pee+l+pI  +lM+dPvvlp s +t+drs+I+++l s+++ +P++r+plt ++++ n +l++ i++w++ +
   Q: 915  APEEYLDPIISTLMTDPVVLPsSKVTVDRSTIARHLLSDQT-DPFNREPLTMDKVKSNEALKQEIESWIQGK 985
           79*******************9******************9.**************************9865 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MTSIEENPFA ALLQEGANSD GVPHKLVEEV LLFTLNKASS SAVLCLADVV VETSEEMLSE 60
DLVAHALFER LMLAETSQYA AGNASEMAME RRAMRYLKGA FTRCGLIQAE RKIDCSKILA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCAACGGTCA CACTACTTAG ACCTTGTCAG ACTTTCAAGT TAAAATCATC TGACAATAAA 60
AACCAATTTT CCCCGATGAC AAGCATCGAG GAGAATCCGT TCGCGGCTCT GCTGCAGGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR019474--Ub_conjug_fac_E4_core
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51698--U_BOX

Pfam

PF04564--U-box
PF10408--Ufd2P_core

SMART

SM00504--Ubox

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0000151--C:ubiquitin ligase complex
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0000209--P:protein polyubiquitination
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

dme:Dmel_CG11070

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000585	Aegilops tauschii	31.44	1.00e-83	303.00
IUUC-Aml-001281	Ailuropoda melanoleuca	34.47	4.00e-137	481.00
IUUC-Apl-003514	Anas platyrhynchos	36.32	1.00e-145	509.00
IUUC-Aca-005167	Anolis carolinensis	35.82	2.00e-132	466.00
IUUC-Ame-010905	Astyanax mexicanus	53.00	4.00e-79	288.00
IUUC-Bta-012413	Bos taurus	34.96	4.00e-140	491.00
IUUC-Bol-015172	Brassica oleracea	31.85	1.00e-85	310.00
IUUC-Bra-016633	Brassica rapa	31.85	5.00e-86	311.00
IUUC-Cja-019715	Callithrix jacchus	35.16	1.00e-138	487.00
IUUC-Cfa-021185	Canis familiaris	35.36	1.00e-142	499.00
IUUC-Cpo-021516	Cavia porcellus	35.32	8.00e-139	487.00
IUUC-Csa-023765	Chlorocebus sabaeus	34.97	4.00e-137	481.00
IUUC-Cho-024614	Choloepus hoffmanni	47.02	2.00e-101	363.00
IUUC-Cin-025532	Ciona intestinalis	34.36	6.00e-109	387.00
IUUC-Csv-025834	Ciona savignyi	46.15	3.00e-34	136.00
IUUC-Dre-028223	Danio rerio	33.54	1.00e-129	457.00
IUUC-Dno-029785	Dasypus novemcinctus	35.10	9.00e-140	490.00
IUUC-Dor-030421	Dipodomys ordii	33.40	7.00e-126	444.00
IUUC-Ete-032767	Echinops telfairi	33.48	3.00e-77	283.00
IUUC-Eca-033587	Equus caballus	35.35	5.00e-141	494.00
IUUC-Fca-035622	Felis catus	34.86	2.00e-141	496.00
IUUC-Fal-037262	Ficedula albicollis	36.69	4.00e-145	508.00
IUUC-Gmo-038686	Gadus morhua	33.98	9.00e-137	480.00
IUUC-Gga-041222	Gallus gallus	36.04	2.00e-145	509.00
IUUC-Gac-042637	Gasterosteus aculeatus	34.15	2.00e-127	449.00
IUUC-Gma-043995	Glycine max	29.15	3.00e-87	316.00
IUUC-Ggo-044685	Gorilla gorilla	35.16	2.00e-138	485.00
IUUC-Hsa-046176	Homo sapiens	35.46	2.00e-139	489.00
IUUC-Itr-048469	Ictidomys tridecemlineatus	47.64	1.00e-105	375.00
IUUC-Lch-049630	Latimeria chalumnae	33.95	2.00e-147	516.00
IUUC-Lpe-051022	Leersia perrieri	29.08	3.00e-81	296.00
IUUC-Loc-052727	Lepisosteus oculatus	33.40	3.00e-130	458.00
IUUC-Laf-054041	Loxodonta africana	34.67	5.00e-140	491.00
IUUC-Mcc-055099	Macaca mulatta	35.46	2.00e-139	489.00
IUUC-Meu-055991	Macropus eugenii	36.09	4.00e-141	494.00
IUUC-Mga-059596	Meleagris gallopavo	36.32	1.00e-145	510.00
IUUC-Mmr-061244	Microcebus murinus	32.12	3.00e-87	315.00
IUUC-Mdo-062335	Monodelphis domestica	36.04	2.00e-142	499.00
IUUC-Mmu-063572	Mus musculus	35.62	1.00e-140	493.00
IUUC-Mpu-066444	Mustela putorius furo	33.56	4.00e-127	448.00
IUUC-Mlu-068232	Myotis lucifugus	34.68	1.00e-139	490.00
IUUC-Nle-070036	Nomascus leucogenys	35.35	6.00e-139	488.00
IUUC-Opr-070503	Ochotona princeps	52.40	2.00e-70	259.00
IUUC-Ont-072389	Oreochromis niloticus	34.26	5.00e-131	461.00
IUUC-Oan-073114	Ornithorhynchus anatinus	35.68	1.00e-142	499.00
IUUC-Ocu-074370	Oryctolagus cuniculus	35.59	9.00e-138	483.00
IUUC-Oba-075073	Oryza barthii	40.44	5.00e-86	311.00
IUUC-Obr-076452	Oryza brachyantha	28.86	9.00e-86	311.00
IUUC-Ogl-077141	Oryza glaberrima	40.44	5.00e-86	311.00
IUUC-Oin-079066	Oryza indica	40.44	3.00e-86	312.00
IUUC-Ome-081263	Oryza meridionalis	40.44	2.00e-86	313.00
IUUC-Oru-085002	Oryza rufipogon	40.44	1.00e-86	314.00
IUUC-Osa-085980	Oryza sativa	40.44	5.00e-86	311.00
IUUC-Ola-086562	Oryzias latipes	33.98	2.00e-133	469.00
IUUC-Oga-088146	Otolemur garnettii	35.43	3.00e-139	488.00
IUUC-Oar-089190	Ovis aries	34.96	8.00e-139	487.00
IUUC-Ptr-090592	Pan troglodytes	35.06	5.00e-138	484.00
IUUC-Pan-092271	Papio anubis	35.46	2.00e-139	489.00
IUUC-Psi-093730	Pelodiscus sinensis	35.70	6.00e-143	501.00
IUUC-Pma-094120	Petromyzon marinus	49.83	3.00e-72	264.00
IUUC-Pfo-097077	Poecilia formosa	34.77	5.00e-133	468.00
IUUC-Pab-098069	Pongo abelii	34.60	2.00e-136	479.00
IUUC-Pca-100762	Procavia capensis	33.43	8.00e-127	447.00
IUUC-Ppe-101230	Prunus persica	31.07	2.00e-90	327.00
IUUC-Pva-103149	Pteropus vampyrus	34.96	1.00e-138	486.00
IUUC-Rno-105342	Rattus norvegicus	35.62	2.00e-141	496.00
IUUC-Sha-106555	Sarcophilus harrisii	35.78	6.00e-144	504.00
IUUC-Sit-109949	Setaria italica	30.95	3.00e-87	316.00
IUUC-Sly-110848	Solanum lycopersicum	39.85	4.00e-79	288.00
IUUC-Sar-113131	Sorex araneus	38.12	3.00e-109	389.00
IUUC-Sbi-113828	Sorghum bicolor	40.39	1.00e-85	310.00
IUUC-Ssc-115841	Sus scrofa	35.06	3.00e-139	489.00
IUUC-Tgu-116823	Taeniopygia guttata	36.42	8.00e-146	510.00
IUUC-Tru-118249	Takifugu rubripes	34.51	8.00e-135	474.00
IUUC-Tni-119848	Tetraodon nigroviridis	33.89	2.00e-136	479.00
IUUC-Tur-126056	Triticum urartu	31.44	1.00e-83	303.00
IUUC-Ttr-129300	Tursiops truncatus	51.68	4.00e-88	319.00
IUUC-Vpa-130215	Vicugna pacos	34.76	1.00e-138	487.00
IUUC-Xtr-132107	Xenopus tropicalis	34.83	2.00e-143	503.00
IUUC-Xma-133824	Xiphophorus maculatus	35.21	5.00e-134	471.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence