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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Dme-031932
UUCD1 version UUC-DrM-00375
Ensembl Protein ID FBpp0077900
UniProt Accession Q9VPH8; B3DMX7; RBBP5_DROME
Genbank Protein ID AAF51573.2; AAL48742.1; ACD81773.1; ACD81779.1
Protein Name Retinoblastoma-binding protein 5 homolog
Genbank Nucleotide ID AE014296; AY071120; BT032759; BT032765
Gene Name Rbbp5; CG5585
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
FBgn0036973 FBtr0078242 FBpp0077900
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDiRefIndexPINAMentha
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 3.90e-17 61.7 65 102
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrtgvllk 37
           H  +v++l++  +++ l+s+s D+++ +WD+ tg l++
   Q: 65   HVHPVCSLSWtrNGHKLLSASTDNNVCIWDVLTGELEH 102
           999********55599*****************99876 PP
   
Organism Drosophila melanogaster
Functional Description
(View)

Functional Description


     Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and of the MLL3/4 complex which also methylates histone H3 'Lys-4'.
 Component of the SET1 complex that specifically di- and trimethylates 'Lys-4' of histone H3 and of the MLL3/4 complex which also methylates histone H3 'Lys-4'.
Protein Sequence
(Fasta)
MNLELLESFG QNYPEEFDGS LDCISLAVTC AFNKYGTLLA VGCNDGRIVI WDFLTRGIAK 60
IISAHVHPVC SLSWTRNGHK LLSASTDNNV CIWDVLTGEL EHKYRFPSPV LKVQFDPRND 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dme-031932|E3,WD_repeat|Drosophila melanogaster
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TGCCATTTTA AAAGAAGAAG ATAGTAAACA AAAATGAATT TGGAGCTACT AGGTGAGATT 60
GCCGCCCATT TTTTATGCTT ATGTAGTAAA TAACTCCAGC TTTATTAAGA ATCTTTCGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dme-031932|E3,WD_repeat|Drosophila melanogaster
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0044665--C:MLL1/2 complex
GO:0044666--C:MLL3/4 complex
GO:0048188--C:Set1C/COMPASS complex
GO:0051568--P:histone H3-K4 methylation
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated
KEGG dme:Dmel_CG5585
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000616 Aegilops tauschii 37.71 7.00e-62 231.00
IUUC-Aml-002118 Ailuropoda melanoleuca 66.53 4.00e-177 613.00
IUUC-Atr-002777 Amborella trichopoda 37.04 4.00e-61 228.00
IUUC-Apl-004056 Anas platyrhynchos 66.67 2.00e-178 618.00
IUUC-Aca-004999 Anolis carolinensis 66.73 3.00e-177 614.00
IUUC-Aly-006092 Arabidopsis lyrata 37.17 3.00e-60 225.00
IUUC-Ath-006947 Arabidopsis thaliana 36.52 9.00e-62 230.00
IUUC-Ago-007753 Ashbya gossypii 31.79 1.00e-38 152.00
IUUC-Acl-008105 Aspergillus clavatus 33.78 1.00e-47 183.00
IUUC-Afl-008633 Aspergillus flavus 34.50 5.00e-48 184.00
IUUC-Afu-009075 Aspergillus fumigatus 37.55 6.00e-31 127.00
IUUC-Ani-009233 Aspergillus nidulans 32.66 2.00e-56 212.00
IUUC-Ang-009695 Aspergillus niger 33.89 7.00e-48 184.00
IUUC-Aor-009988 Aspergillus oryzae 34.50 5.00e-48 184.00
IUUC-Ate-010313 Aspergillus terreus 32.59 5.00e-47 181.00
IUUC-Ame-011134 Astyanax mexicanus 61.57 2.00e-156 544.00
IUUC-Bgr-012302 Blumeria graminis 35.04 8.00e-49 187.00
IUUC-Bta-012946 Bos taurus 67.14 0.00e+00 625.00
IUUC-Bci-013968 Botrytis cinerea 34.79 4.00e-52 197.00
IUUC-Bdi-014387 Brachypodium distachyon 37.99 1.00e-69 256.00
IUUC-Bra-017414 Brassica rapa 37.23 2.00e-62 232.00
IUUC-Cel-018610 Caenorhabditis elegans 40.98 2.00e-82 298.00
IUUC-Cja-019938 Callithrix jacchus 66.74 1.00e-176 612.00
IUUC-Cfa-020726 Canis familiaris 66.33 5.00e-179 619.00
IUUC-Cpo-021560 Cavia porcellus 75.62 3.00e-144 503.00
IUUC-Cre-022588 Chlamydomonas reinhardtii 47.83 1.00e-27 117.00
IUUC-Csa-024192 Chlorocebus sabaeus 67.14 0.00e+00 625.00
IUUC-Cho-024355 Choloepus hoffmanni 70.83 4.00e-177 613.00
IUUC-Cin-025285 Ciona intestinalis 59.88 2.00e-168 584.00
IUUC-Csv-026366 Ciona savignyi 61.80 1.00e-163 568.00
IUUC-Cgl-026450 Colletotrichum gloeosporioides 31.45 1.00e-42 166.00
IUUC-Cne-027092 Cryptococcus neoformans 34.68 4.00e-53 201.00
IUUC-Cme-027137 Cyanidioschyzon merolae 33.83 1.00e-27 117.00
IUUC-Dre-027374 Danio rerio 68.20 8.00e-178 615.00
IUUC-Dno-030003 Dasypus novemcinctus 63.60 8.00e-164 569.00
IUUC-Dor-030355 Dipodomys ordii 66.94 3.00e-180 624.00
IUUC-Dse-031442 Dothistroma septosporum 33.85 5.00e-52 197.00
IUUC-Ete-032858 Echinops telfairi 59.72 2.00e-123 434.00
IUUC-Eca-034217 Equus caballus 67.13 0.00e+00 625.00
IUUC-Eeu-035024 Erinaceus europaeus 64.30 3.00e-177 613.00
IUUC-Fca-035370 Felis catus 66.74 5.00e-177 613.00
IUUC-Fal-036628 Ficedula albicollis 75.00 3.00e-167 580.00
IUUC-Fox-037739 Fusarium oxysporum 31.04 3.00e-44 171.00
IUUC-Fso-038094 Fusarium solani 32.53 3.00e-45 175.00
IUUC-Gmo-039088 Gadus morhua 65.16 8.00e-170 589.00
IUUC-Ggr-040063 Gaeumannomyces graminis 32.71 1.00e-53 203.00
IUUC-Gga-041160 Gallus gallus 67.34 0.00e+00 625.00
IUUC-Gac-041333 Gasterosteus aculeatus 65.26 4.00e-173 600.00
IUUC-Gma-044271 Glycine max 35.96 6.00e-64 237.00
IUUC-Ggo-044657 Gorilla gorilla 67.14 0.00e+00 625.00
IUUC-Hsa-045894 Homo sapiens 67.14 0.00e+00 625.00
IUUC-Hvu-047662 Hordeum vulgare 36.93 1.00e-62 233.00
IUUC-Itr-048125 Ictidomys tridecemlineatus 65.61 4.00e-166 577.00
IUUC-Kpa-049095 Komagataella pastoris 30.70 1.00e-36 146.00
IUUC-Lch-049495 Latimeria chalumnae 54.55 4.00e-95 340.00
IUUC-Lpe-051038 Leersia perrieri 34.95 3.00e-54 205.00
IUUC-Loc-052680 Lepisosteus oculatus 67.67 0.00e+00 629.00
IUUC-Laf-053717 Loxodonta africana 66.67 2.00e-177 614.00
IUUC-Mcc-055007 Macaca mulatta 64.14 4.00e-167 580.00
IUUC-Meu-056494 Macropus eugenii 61.75 2.00e-59 222.00
IUUC-Mor-057173 Magnaporthe oryzae 33.89 1.00e-55 209.00
IUUC-Mpo-057622 Magnaporthe poae 32.62 4.00e-54 204.00
IUUC-Mtr-057672 Medicago truncatula 35.53 4.00e-67 248.00
IUUC-Mla-059057 Melampsora laricipopulina 34.88 5.00e-49 187.00
IUUC-Mga-060037 Meleagris gallopavo 66.46 1.00e-177 615.00
IUUC-Mvi-060321 Microbotryum violaceum 34.41 1.00e-52 199.00
IUUC-Mmr-060755 Microcebus murinus 65.64 2.00e-173 601.00
IUUC-Mdo-061859 Monodelphis domestica 66.93 2.00e-180 624.00
IUUC-Mmu-063755 Mus musculus 66.93 0.00e+00 626.00
IUUC-Mac-065292 Musa acuminata 39.50 8.00e-70 258.00
IUUC-Mpu-065896 Mustela putorius furo 67.14 2.00e-180 624.00
IUUC-Mlu-067927 Myotis lucifugus 66.46 2.00e-177 614.00
IUUC-Nfi-068429 Neosartorya fischeri 34.11 2.00e-48 185.00
IUUC-Ncr-068738 Neurospora crassa 32.56 4.00e-48 184.00
IUUC-Nle-069608 Nomascus leucogenys 67.14 0.00e+00 625.00
IUUC-Opr-070319 Ochotona princeps 66.87 7.00e-177 612.00
IUUC-Ont-071451 Oreochromis niloticus 66.73 1.00e-179 622.00
IUUC-Oan-073445 Ornithorhynchus anatinus 70.88 3.00e-171 593.00
IUUC-Ocu-074341 Oryctolagus cuniculus 67.14 0.00e+00 625.00
IUUC-Oba-075664 Oryza barthii 36.01 3.00e-60 225.00
IUUC-Obr-076630 Oryza brachyantha 34.79 2.00e-57 216.00
IUUC-Ogl-077847 Oryza glaberrima 36.01 3.00e-60 225.00
IUUC-Ogu-077970 Oryza glumaepatula 37.16 1.00e-57 216.00
IUUC-Oin-079374 Oryza indica 36.01 3.00e-60 225.00
IUUC-Olo-080992 Oryza longistaminata 36.01 3.00e-60 225.00
IUUC-Ome-081683 Oryza meridionalis 36.01 2.00e-58 219.00
IUUC-Oni-082594 Oryza nivara 36.01 3.00e-60 225.00
IUUC-Opu-083907 Oryza punctata 36.36 1.00e-60 226.00
IUUC-Oru-084400 Oryza rufipogon 36.01 3.00e-60 225.00
IUUC-Osa-085442 Oryza sativa 36.01 3.00e-60 225.00
IUUC-Ola-086569 Oryzias latipes 70.89 2.00e-174 604.00
IUUC-Oga-088947 Otolemur garnettii 62.40 1.00e-159 555.00
IUUC-Oar-090358 Ovis aries 66.53 1.00e-176 612.00
IUUC-Ptr-091601 Pan troglodytes 67.14 1.00e-180 625.00
IUUC-Pan-092466 Papio anubis 67.14 0.00e+00 625.00
IUUC-Psi-093614 Pelodiscus sinensis 66.67 2.00e-178 618.00
IUUC-Pma-094450 Petromyzon marinus 76.81 1.00e-168 585.00
IUUC-Pno-094819 Phaeosphaeria nodorum 33.73 3.00e-47 182.00
IUUC-Ppa-095157 Physcomitrella patens 36.68 6.00e-29 120.00
IUUC-Pfo-096312 Poecilia formosa 66.40 3.00e-178 617.00
IUUC-Pab-098058 Pongo abelii 67.14 0.00e+00 625.00
IUUC-Pop-099447 Populus trichocarpa 37.66 3.00e-64 238.00
IUUC-Pca-100623 Procavia capensis 64.11 2.00e-170 591.00
IUUC-Ppe-102053 Prunus persica 38.41 2.00e-69 255.00
IUUC-Pva-102779 Pteropus vampyrus 64.71 1.00e-170 592.00
IUUC-Pgr-103398 Puccinia graminis 36.76 3.00e-52 198.00
IUUC-Ptt-103912 Puccinia triticina 37.63 3.00e-53 201.00
IUUC-Pte-104246 Pyrenophora teres 33.86 1.00e-48 186.00
IUUC-Pyt-104582 Pyrenophora triticirepentis 33.41 5.00e-48 184.00
IUUC-Rno-104838 Rattus norvegicus 66.93 0.00e+00 625.00
IUUC-Sce-106229 Saccharomyces cerevisiae 29.87 9.00e-34 137.00
IUUC-Sha-106527 Sarcophilus harrisii 66.93 1.00e-180 625.00
IUUC-Sja-107862 Schizosaccharomyces japonicus 35.26 5.00e-57 214.00
IUUC-Spo-108025 Schizosaccharomyces pombe 36.16 3.00e-53 201.00
IUUC-Ssl-108544 Sclerotinia sclerotiorum 35.04 5.00e-51 194.00
IUUC-Smo-109474 Selaginella moellendorffii 34.91 4.00e-51 194.00
IUUC-Sit-110687 Setaria italica 37.01 3.00e-58 218.00
IUUC-Sly-111597 Solanum lycopersicum 35.41 4.00e-59 221.00
IUUC-Stu-112389 Solanum tuberosum 35.97 2.00e-59 222.00
IUUC-Sar-113284 Sorex araneus 57.61 6.00e-141 493.00
IUUC-Sbi-114362 Sorghum bicolor 35.11 2.00e-57 216.00
IUUC-Sre-115146 Sporisorium reilianum 29.80 6.00e-41 161.00
IUUC-Ssc-115604 Sus scrofa 66.74 5.00e-177 613.00
IUUC-Tgu-117010 Taeniopygia guttata 43.05 9.00e-17 79.00
IUUC-Tru-118258 Takifugu rubripes 66.67 2.00e-177 614.00
IUUC-Tsy-119169 Tarsius syrichta 73.31 7.00e-141 493.00
IUUC-Tni-119939 Tetraodon nigroviridis 66.13 3.00e-175 607.00
IUUC-Tca-121010 Theobroma cacao 36.31 4.00e-66 244.00
IUUC-Tre-121944 Trichoderma reesei 32.75 1.00e-47 182.00
IUUC-Tvi-122283 Trichoderma virens 33.42 1.00e-47 182.00
IUUC-Tur-126395 Triticum urartu 36.96 8.00e-64 237.00
IUUC-Tme-127150 Tuber melanosporum 37.73 5.00e-62 231.00
IUUC-Tbe-127745 Tupaia belangeri 61.04 8.00e-106 376.00
IUUC-Ttr-129187 Tursiops truncatus 66.33 4.00e-171 593.00
IUUC-Uma-129654 Ustilago maydis 29.14 2.00e-37 149.00
IUUC-Vda-129788 Verticillium dahliae 30.36 1.00e-48 186.00
IUUC-Vpa-130182 Vicugna pacos 65.17 3.00e-136 477.00
IUUC-Vvi-131557 Vitis vinifera 37.61 5.00e-67 248.00
IUUC-Xtr-132007 Xenopus tropicalis 68.33 5.00e-179 620.00
IUUC-Xma-133909 Xiphophorus maculatus 67.13 5.00e-179 620.00
IUUC-Yli-134524 Yarrowia lipolytica 36.29 1.00e-56 213.00
IUUC-Zma-134821 Zea mays 36.83 3.00e-59 221.00
Created Date 25-Jun-2017

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