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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063599
UUCD1 version UUC-MuM-01202
Ensembl Protein ID ENSMUSP00000106938.3
UniProt Accession A0A0R4J1F5; A0A0R4J1F5_MOUSE
Genbank Protein ID ENSMUSP00000106938
Protein Name Ubiquitin carboxyl-terminal hydrolase 21
Genbank Nucleotide ID AC084821
Gene Name Usp21
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000053483.13 ENSMUST00000065941.11 ENSMUSP00000064002.5
ENSMUSG00000053483.13 ENSMUST00000149187.7 ENSMUSP00000120161.1
ENSMUSG00000053483.13 ENSMUST00000111306.9 ENSMUSP00000106938.3
ENSMUSG00000053483.13 ENSMUST00000174720.1 ENSMUSP00000133362.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemicroRNATRANSFACRepTar
RAID2
Post-translational Modifications (PTMs)
PHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 3.30e-87 294.0 212 560
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNt...CYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeef 84
           +Gl+NlgNt   C++N+vLQcLs++++lr+++l+  ++++++     ++ +el++++++++ +lw  ++ +av+p+++ ++++k+ ++f
   Q: 212  VGLRNLGNTlpqCFLNAVLQCLSSTRPLRDFCLRrDFRQEVPG---GGRAQELTEAFADVIGALWhPDSCEAVNPTRFRAVFQKYVPSF 297
           6*******9999**********************667777776...5789***************888899****************** PP
   S: 85   sgyeqqDaqEflaflldqleeelkk...................eknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqi 154
           sgy+qqDaqEfl+ l+++l+ e+++                   +     +ee e ++ ++ +  +++  ++++s i+dlF gqlks +
   Q: 298  SGYSQQDAQEFLKLLMERLHLEINRrgrrappilasgpvpsppcRGGGALHEEPELSDDDRANLMWKRYLEREDSKIVDLFVGQLKSCL 386
           ***********************999988999988888888777444444444444445566779************************ PP
   S: 155  kclecdnvssreepfldlslpvpgkeet.kkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfsee 242
           kc++c+ +s+++e f+dlslp+p+k     k sl+dc++ ftkeeele+en+  c++c++k++++kkl+++++P++L+lhL+Rf  s +
   Q: 387  KCQACGYRSTTFEVFCDLSLPIPKKGFAgGKVSLRDCFSLFTKEEELESENAPVCDRCRQKTRSTKKLTVQRFPRILVLHLNRF--STS 473
           ***********************887541456****************************************************..666 PP
   S: 243  qksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevleetgsta 330
           ++s +k +  v+fpl+ L+l  f +++      +  Y+L+a ++HsGs++ GHY+a+++  + +W  ++Ds+V++v+e++v +   s++
   Q: 474  RGSIKKSSVGVDFPLQrLSLGDFASDKAG----SPVYQLYALCNHSGSVHYGHYTALCRC-QTGWHVYNDSRVSPVSENQVAS---SEG 554
           79999**********99*******99543....78*************************.777*******************...*** PP
   S: 331  YvlfYk 336
           YvlfY+
   Q: 555  YVLFYQ 560
           *****8 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MPQASEHRLG RTREPPVNVQ PRVGAKIPFP PRARSKERRN PVPGPNSMLR PLPPRPGPPD 60
ERLKKLELGR GRTSGSRPRG PLRADHGVPL PGSPPPAVAL PLPSRTNLAR SKSVSSGDLR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063599|DUB,USP|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GATTCCGAGT GTGGGCGCGC AGGCGCCTAA GAGACTGTGA AGCCGGTGGC CGGTGGCCGG 60
GCGGCACCAA CAAAGATGGC GGCGGCCCTT GCGGCGGGAG CAAGCTGGGC AACAGCTGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063599|DUB,USP|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
PROSITE

PS00973--USP_2
PS50235--USP_3
Pfam

PF00443--UCH
Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001858 Ailuropoda melanoleuca 95.43 0.00e+00 966.00
IUUC-Aca-004612 Anolis carolinensis 58.67 6.00e-172 597.00
IUUC-Ame-011548 Astyanax mexicanus 51.68 2.00e-101 362.00
IUUC-Bta-012626 Bos taurus 95.08 0.00e+00 939.00
IUUC-Cja-018853 Callithrix jacchus 95.78 0.00e+00 991.00
IUUC-Cfa-021167 Canis familiaris 95.96 0.00e+00 956.00
IUUC-Cpo-021305 Cavia porcellus 95.44 0.00e+00 945.00
IUUC-Csa-023454 Chlorocebus sabaeus 95.96 0.00e+00 989.00
IUUC-Cho-024836 Choloepus hoffmanni 95.34 4.00e-106 378.00
IUUC-Dre-028454 Danio rerio 53.07 8.00e-106 377.00
IUUC-Dno-029955 Dasypus novemcinctus 89.69 4.00e-174 604.00
IUUC-Dor-031053 Dipodomys ordii 95.08 0.00e+00 1004.00
IUUC-Ete-032416 Echinops telfairi 93.66 2.00e-140 492.00
IUUC-Eca-033817 Equus caballus 94.38 0.00e+00 969.00
IUUC-Fca-036400 Felis catus 93.70 0.00e+00 946.00
IUUC-Gmo-038926 Gadus morhua 53.63 2.00e-102 365.00
IUUC-Gac-041331 Gasterosteus aculeatus 52.46 2.00e-105 375.00
IUUC-Ggo-045174 Gorilla gorilla 95.96 0.00e+00 989.00
IUUC-Hsa-046443 Homo sapiens 95.78 0.00e+00 982.00
IUUC-Itr-048329 Ictidomys tridecemlineatus 96.13 0.00e+00 989.00
IUUC-Lch-050539 Latimeria chalumnae 61.76 9.00e-106 377.00
IUUC-Loc-051808 Lepisosteus oculatus 54.92 3.00e-113 401.00
IUUC-Laf-053730 Loxodonta africana 93.18 0.00e+00 975.00
IUUC-Mcc-055541 Macaca mulatta 95.96 0.00e+00 989.00
IUUC-Meu-056279 Macropus eugenii 89.12 0.00e+00 924.00
IUUC-Mmr-060913 Microcebus murinus 95.78 0.00e+00 937.00
IUUC-Mdo-061807 Monodelphis domestica 89.65 0.00e+00 877.00
IUUC-Mpu-066329 Mustela putorius furo 95.96 0.00e+00 954.00
IUUC-Mlu-067359 Myotis lucifugus 92.80 0.00e+00 853.00
IUUC-Nle-068975 Nomascus leucogenys 93.67 0.00e+00 961.00
IUUC-Opr-071096 Ochotona princeps 93.85 0.00e+00 929.00
IUUC-Ocu-074228 Oryctolagus cuniculus 96.49 0.00e+00 966.00
IUUC-Ola-086684 Oryzias latipes 49.86 8.00e-100 357.00
IUUC-Oga-088007 Otolemur garnettii 77.89 0.00e+00 756.00
IUUC-Oar-090226 Ovis aries 94.62 0.00e+00 728.00
IUUC-Ptr-091522 Pan troglodytes 95.96 0.00e+00 989.00
IUUC-Pan-091954 Papio anubis 95.61 0.00e+00 982.00
IUUC-Psi-093216 Pelodiscus sinensis 60.13 0.00e+00 665.00
IUUC-Pfo-096257 Poecilia formosa 49.58 2.00e-100 358.00
IUUC-Pab-098691 Pongo abelii 95.78 0.00e+00 988.00
IUUC-Pca-101133 Procavia capensis 87.35 0.00e+00 909.00
IUUC-Pva-102681 Pteropus vampyrus 92.27 0.00e+00 900.00
IUUC-Rno-105132 Rattus norvegicus 97.72 0.00e+00 976.00
IUUC-Sha-107145 Sarcophilus harrisii 89.46 0.00e+00 843.00
IUUC-Ssc-115586 Sus scrofa 95.96 0.00e+00 940.00
IUUC-Tgu-117491 Taeniopygia guttata 80.66 3.00e-113 400.00
IUUC-Tni-120746 Tetraodon nigroviridis 51.32 3.00e-93 335.00
IUUC-Tbe-127465 Tupaia belangeri 98.14 3.00e-125 442.00
IUUC-Ttr-128274 Tursiops truncatus 92.97 0.00e+00 909.00
IUUC-Xtr-131989 Xenopus tropicalis 49.15 1.00e-126 446.00
Created Date 25-Jun-2017

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