iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107164

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01002505

Gene Name

USP54

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000004835.1	ENSSHAT00000005587.1	ENSSHAP00000005533.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.70e-24	86.8	32	349

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNl..gNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavspre.....llkalkkeaee 83
           Gl+N   +N+C++NS+LQ+L+++  +r+ + + +++k+  +       ++ ++l+ +f++++ +++++v p++     l k++++e+ +
   Q: 32   GLSNEpgQNSCFLNSALQVLWHLDIFRRSFRQLTTHKCMGD------SCIFCALKGIFNQFQ-CSSEKVLPSDtlrsaLAKTFQDEQ-R 112
           88887668******************************986......59************5.555555555543333555555444.5 PP
   S: 84   fsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           f+     Da E+++ ll +++ ++                    de +e+  +  +++ ++ F ++l +q++c +c+ +s    pf+++
   Q: 113  FQLGIMDDAAECFENLLMRIHFHI-------------------ADETKEDICTAAHCISHQKFAMTLFEQCVCTSCGATSDPL-PFIQM 181
           99**********************...................3455677899*************************99766.9**** PP
   S: 173  slpvpgkeetkke.............slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
              ++  + +++               + ++L++ ++   l+       ++c +k +  +++ l + P+++++ L +   s + +  e 
   Q: 182  VHYISTTSLCNQAicmlerrekpspgMFGELLQKASTMGDLR----NCPSNCGEKIR-IRRV-LMNAPQIITIGLVWD--SDHSDLAED 262
           *****9999988899999999965555555555555555555....67788888886.5555.5567**********9..333344444 PP
   S: 249  inkkvefpleLdlsp..fctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtev..keeevleetg...st 329
           +  ++ +   L+l    f ++ ++  k+++ Y L+++++++G     HY ++  ++k + W++fdD +V+e+  k+++v++++     +
   Q: 263  VIHSLGTC--LKLGDlfFRVT-DDRAKQSELY-LVGMICYYG----KHYSTFFFQTKIRkWMYFDDAHVKEIgpKWKDVVTKCIkghYQ 343
           44444444..55555213333.3333335555.*********....9*****99987767************76689998865555555 PP
   S: 330  aYvlfY 335
           + +l+Y
   Q: 344  PLLLLY 349
           556666 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MSWKRNYFSV GRGSVQGMFA PRSSTSIAPS KGLSNEPGQN SCFLNSALQV LWHLDIFRRS 60
FRQLTTHKCM GDSCIFCALK GIFNQFQCSS EKVLPSDTLR SALAKTFQDE QRFQLGIMDD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACTCTGGCA GGGCTGGCTA TTCCAGTCAC AGAAGAAAAG AGGAGACAGA GCTCTCTGAT 60
GTTCTGGATG GGTGACTAGA AGAATTTTTG GCAAAGGAAA AACAAAGCAC AATGTGCATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028889--USP_dom

PROSITE

PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination

KEGG

shr:100914856

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000820	Aegilops tauschii	31.36	1.00e-19	90.50
IUUC-Aml-001414	Ailuropoda melanoleuca	69.51	0.00e+00	1916.00
IUUC-Apl-004044	Anas platyrhynchos	80.25	0.00e+00	1209.00
IUUC-Aca-004351	Anolis carolinensis	59.28	0.00e+00	1545.00
IUUC-Aly-005468	Arabidopsis lyrata	32.51	2.00e-42	168.00
IUUC-Ath-006682	Arabidopsis thaliana	32.29	4.00e-42	167.00
IUUC-Ame-011525	Astyanax mexicanus	61.48	0.00e+00	968.00
IUUC-Bta-013344	Bos taurus	68.31	0.00e+00	1895.00
IUUC-Bdi-015058	Brachypodium distachyon	32.69	2.00e-41	164.00
IUUC-Bol-015670	Brassica oleracea	31.50	2.00e-39	157.00
IUUC-Bra-016731	Brassica rapa	32.08	9.00e-42	166.00
IUUC-Cja-018724	Callithrix jacchus	68.11	0.00e+00	1867.00
IUUC-Cfa-021222	Canis familiaris	69.33	0.00e+00	1974.00
IUUC-Cpo-021795	Cavia porcellus	70.28	0.00e+00	1634.00
IUUC-Csa-023262	Chlorocebus sabaeus	69.16	0.00e+00	1916.00
IUUC-Cho-024422	Choloepus hoffmanni	66.85	0.00e+00	1529.00
IUUC-Cin-025752	Ciona intestinalis	68.60	4.00e-49	186.00
IUUC-Csv-026063	Ciona savignyi	56.10	7.00e-112	396.00
IUUC-Dre-028046	Danio rerio	62.81	0.00e+00	938.00
IUUC-Dno-029417	Dasypus novemcinctus	65.92	0.00e+00	1740.00
IUUC-Dor-030653	Dipodomys ordii	51.35	3.00e-165	576.00
IUUC-Dme-032071	Drosophila melanogaster	53.82	2.00e-104	374.00
IUUC-Eca-033235	Equus caballus	70.22	0.00e+00	1719.00
IUUC-Eeu-034975	Erinaceus europaeus	43.68	1.00e-135	476.00
IUUC-Fca-036070	Felis catus	69.88	0.00e+00	1988.00
IUUC-Fal-037089	Ficedula albicollis	59.75	0.00e+00	1670.00
IUUC-Gmo-038653	Gadus morhua	74.93	3.00e-173	600.00
IUUC-Gga-041241	Gallus gallus	59.60	0.00e+00	1672.00
IUUC-Gac-042157	Gasterosteus aculeatus	80.46	0.00e+00	683.00
IUUC-Ggo-045626	Gorilla gorilla	69.45	0.00e+00	1940.00
IUUC-Hsa-045767	Homo sapiens	69.57	0.00e+00	1941.00
IUUC-Hvu-047657	Hordeum vulgare	31.94	3.00e-42	167.00
IUUC-Itr-048187	Ictidomys tridecemlineatus	61.21	0.00e+00	1764.00
IUUC-Lch-049712	Latimeria chalumnae	88.05	0.00e+00	715.00
IUUC-Lpe-051572	Leersia perrieri	32.35	7.00e-39	156.00
IUUC-Loc-052615	Lepisosteus oculatus	66.99	0.00e+00	999.00
IUUC-Laf-054578	Loxodonta africana	63.07	0.00e+00	1700.00
IUUC-Mcc-054696	Macaca mulatta	68.81	0.00e+00	1916.00
IUUC-Meu-056841	Macropus eugenii	75.65	0.00e+00	1098.00
IUUC-Mga-059393	Meleagris gallopavo	89.14	4.00e-171	593.00
IUUC-Mmr-060701	Microcebus murinus	67.42	0.00e+00	1828.00
IUUC-Mdo-062433	Monodelphis domestica	82.93	0.00e+00	2469.00
IUUC-Mmu-063480	Mus musculus	59.98	0.00e+00	1656.00
IUUC-Mpu-066404	Mustela putorius furo	68.62	0.00e+00	1991.00
IUUC-Mlu-067841	Myotis lucifugus	54.97	0.00e+00	966.00
IUUC-Nle-070110	Nomascus leucogenys	71.00	0.00e+00	1709.00
IUUC-Opr-070676	Ochotona princeps	73.71	0.00e+00	1099.00
IUUC-Ont-072289	Oreochromis niloticus	71.29	0.00e+00	707.00
IUUC-Oan-073551	Ornithorhynchus anatinus	66.19	0.00e+00	1615.00
IUUC-Ocu-074729	Oryctolagus cuniculus	67.96	0.00e+00	1927.00
IUUC-Obr-076268	Oryza brachyantha	31.69	7.00e-43	169.00
IUUC-Ogl-077138	Oryza glaberrima	31.10	6.00e-40	160.00
IUUC-Opu-083823	Oryza punctata	31.40	1.00e-40	162.00
IUUC-Ola-086742	Oryzias latipes	79.36	0.00e+00	648.00
IUUC-Oga-088920	Otolemur garnettii	70.47	0.00e+00	1641.00
IUUC-Oar-089644	Ovis aries	68.43	0.00e+00	1880.00
IUUC-Ptr-091530	Pan troglodytes	71.00	0.00e+00	1717.00
IUUC-Pan-092190	Papio anubis	81.78	0.00e+00	1391.00
IUUC-Psi-094022	Pelodiscus sinensis	60.15	0.00e+00	1635.00
IUUC-Pma-094745	Petromyzon marinus	60.16	2.00e-135	474.00
IUUC-Pfo-096072	Poecilia formosa	78.92	0.00e+00	697.00
IUUC-Pab-097979	Pongo abelii	70.98	0.00e+00	1594.00
IUUC-Pop-099539	Populus trichocarpa	31.10	1.00e-36	149.00
IUUC-Pca-101005	Procavia capensis	57.78	0.00e+00	1468.00
IUUC-Pva-103125	Pteropus vampyrus	68.77	0.00e+00	1900.00
IUUC-Rno-105463	Rattus norvegicus	63.45	0.00e+00	1724.00
IUUC-Sit-110021	Setaria italica	32.26	7.00e-38	153.00
IUUC-Stu-112904	Solanum tuberosum	30.90	3.00e-37	150.00
IUUC-Sar-113423	Sorex araneus	44.02	4.00e-128	452.00
IUUC-Sbi-114345	Sorghum bicolor	32.84	6.00e-42	166.00
IUUC-Ssc-116206	Sus scrofa	68.22	0.00e+00	1851.00
IUUC-Tgu-116521	Taeniopygia guttata	74.00	0.00e+00	1261.00
IUUC-Tru-118155	Takifugu rubripes	70.45	4.00e-172	597.00
IUUC-Tsy-118998	Tarsius syrichta	66.10	0.00e+00	1683.00
IUUC-Tni-120257	Tetraodon nigroviridis	80.61	0.00e+00	664.00
IUUC-Tca-121692	Theobroma cacao	31.29	4.00e-38	154.00
IUUC-Tae-125619	Triticum aestivum	32.22	3.00e-43	171.00
IUUC-Tur-126027	Triticum urartu	31.75	6.00e-43	170.00
IUUC-Ttr-128290	Tursiops truncatus	70.27	0.00e+00	1516.00
IUUC-Vpa-130213	Vicugna pacos	67.88	0.00e+00	1609.00
IUUC-Vvi-131652	Vitis vinifera	30.70	2.00e-38	155.00
IUUC-Xtr-131831	Xenopus tropicalis	52.22	0.00e+00	1373.00
IUUC-Xma-133409	Xiphophorus maculatus	59.05	0.00e+00	825.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence