iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0003654	FBtr0089407	FBpp0088429
FBgn0003654	FBtr0089401	FBpp0088423
FBgn0003654	FBtr0340360	FBpp0309318
FBgn0003654	FBtr0089400	FBpp0088422
FBgn0003654	FBtr0089398	FBpp0088420
FBgn0003654	FBtr0089405	FBpp0088427
FBgn0003654	FBtr0089403	FBpp0088425
FBgn0003654	FBtr0089402	FBpp0088424
FBgn0003654	FBtr0089404	FBpp0088426
FBgn0003654	FBtr0089399	FBpp0088421
FBgn0003654	FBtr0340361	FBpp0309319
FBgn0003654	FBtr0089406	FBpp0088428

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein 3D Structure
PDB	MMDB
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.40e-15	56.8	372	397

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 9    laf....sdtllvsGsdDgtikvWDlr 31
            +f    + +l++ G++ g+i +WD r
   Q: 372  TCFakfnP-NLILGGTYSGQIVLWDNR 397
           44555343.9***************65 PP

Organism

Drosophila melanogaster

Functional Description
(View)

Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the help dynein bind to dynactin 150 kDa component (By similarity).

Protein Sequence
(Fasta)

MDRKAELERK KAKLAALREE KDRRRREKEI KDMEEAAGRI GGGAGIDKDQ RKDLDEMLSS 60
LGVAPVSEVL SSLSSVNSMT SDNSNTQTPD ASLQATVNGQ SGGKKQPLNL SVYNVQATNI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTCACAGC TATCGCCGTA CAGTAGTAAA ATCTTATTCT TGTGTTTAAA CTTGTGTTAA 60
TTAAGAATTC GGAATCCCGC TAAGAATCCT AGTCTTCCAC ACCCTTTGGG CATCTATGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0243--Dynein
KW-0458--Lysosome
KW-0472--Membrane
KW-0493--Microtubule
KW-0505--Motor protein
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0813--Transport
KW-0853--WD repeat

Interpro

IPR025956--DYNC1I1/DYNC1I2
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF11540--Dynein_IC2

SMART

SM00320--WD40

Gene Ontology

GO:0005868--C:cytoplasmic dynein complex
GO:0005765--C:lysosomal membrane
GO:0005874--C:microtubule
GO:0005875--C:microtubule associated complex
GO:0043005--C:neuron projection
GO:0031965--C:nuclear membrane
GO:0034452--F:dynactin binding
GO:0045504--F:dynein heavy chain binding
GO:0045503--F:dynein light chain binding
GO:0003774--F:motor activity
GO:0008088--P:axo-dendritic transport
GO:0007349--P:cellularization
GO:0051642--P:centrosome localization
GO:0001754--P:eye photoreceptor cell differentiation
GO:0000226--P:microtubule cytoskeleton organization
GO:0007018--P:microtubule-based movement
GO:0034501--P:protein localization to kinetochore
GO:0007291--P:sperm individualization
GO:0007051--P:spindle organization

KEGG

dme:Dmel_CG18000

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002108	Ailuropoda melanoleuca	62.65	2.00e-168	585.00
IUUC-Apl-003265	Anas platyrhynchos	63.39	8.00e-165	572.00
IUUC-Aca-004911	Anolis carolinensis	63.92	2.00e-170	591.00
IUUC-Acl-008245	Aspergillus clavatus	37.31	3.00e-77	282.00
IUUC-Afu-009032	Aspergillus fumigatus	36.02	2.00e-76	279.00
IUUC-Ani-009498	Aspergillus nidulans	37.24	1.00e-82	300.00
IUUC-Ame-011786	Astyanax mexicanus	62.39	1.00e-168	585.00
IUUC-Bta-013557	Bos taurus	62.27	8.00e-169	586.00
IUUC-Cel-018207	Caenorhabditis elegans	44.42	1.00e-98	353.00
IUUC-Cho-025102	Choloepus hoffmanni	51.62	2.00e-128	452.00
IUUC-Cne-026971	Cryptococcus neoformans	45.31	2.00e-108	385.00
IUUC-Dre-028465	Danio rerio	63.61	2.00e-168	585.00
IUUC-Dor-030613	Dipodomys ordii	62.27	3.00e-168	584.00
IUUC-Dse-031518	Dothistroma septosporum	36.45	8.00e-72	264.00
IUUC-Ete-032322	Echinops telfairi	54.92	9.00e-143	499.00
IUUC-Eca-033654	Equus caballus	62.80	7.00e-170	589.00
IUUC-Fca-035962	Felis catus	62.65	2.00e-168	585.00
IUUC-Fal-037591	Ficedula albicollis	63.46	2.00e-165	575.00
IUUC-Fox-037992	Fusarium oxysporum	37.50	7.00e-84	304.00
IUUC-Fso-038209	Fusarium solani	37.30	4.00e-81	295.00
IUUC-Gga-040996	Gallus gallus	63.46	3.00e-165	574.00
IUUC-Itr-048711	Ictidomys tridecemlineatus	63.03	3.00e-170	591.00
IUUC-Lch-050416	Latimeria chalumnae	63.33	5.00e-167	580.00
IUUC-Loc-051856	Lepisosteus oculatus	64.02	7.00e-164	569.00
IUUC-Lma-052957	Leptosphaeria maculans	31.22	7.00e-59	221.00
IUUC-Laf-054418	Loxodonta africana	62.44	2.00e-170	591.00
IUUC-Meu-056899	Macropus eugenii	63.20	7.00e-167	579.00
IUUC-Mor-056924	Magnaporthe oryzae	39.39	2.00e-92	332.00
IUUC-Mga-060055	Meleagris gallopavo	63.46	2.00e-165	575.00
IUUC-Mvi-060541	Microbotryum violaceum	41.44	2.00e-101	362.00
IUUC-Mdo-061887	Monodelphis domestica	63.79	1.00e-166	578.00
IUUC-Mpu-065831	Mustela putorius furo	63.68	2.00e-168	585.00
IUUC-Mlu-066987	Myotis lucifugus	63.29	2.00e-167	582.00
IUUC-Nfi-068441	Neosartorya fischeri	36.13	6.00e-77	281.00
IUUC-Opr-070509	Ochotona princeps	62.23	2.00e-164	571.00
IUUC-Ont-071319	Oreochromis niloticus	63.27	8.00e-169	586.00
IUUC-Oan-073420	Ornithorhynchus anatinus	63.55	6.00e-166	576.00
IUUC-Ola-086484	Oryzias latipes	63.74	3.00e-171	594.00
IUUC-Oar-090204	Ovis aries	62.80	3.00e-170	591.00
IUUC-Psi-092969	Pelodiscus sinensis	62.65	3.00e-169	587.00
IUUC-Pno-095122	Phaeosphaeria nodorum	35.56	5.00e-76	278.00
IUUC-Pfo-097067	Poecilia formosa	62.89	6.00e-166	576.00
IUUC-Pca-100827	Procavia capensis	64.07	8.00e-122	430.00
IUUC-Pva-102223	Pteropus vampyrus	62.50	8.00e-169	586.00
IUUC-Ptt-103792	Puccinia triticina	40.45	1.00e-101	363.00
IUUC-Pte-104046	Pyrenophora teres	35.52	5.00e-73	268.00
IUUC-Pyt-104796	Pyrenophora triticirepentis	36.38	1.00e-70	260.00
IUUC-Rno-105916	Rattus norvegicus	62.07	6.00e-173	600.00
IUUC-Sha-107044	Sarcophilus harrisii	63.79	7.00e-167	579.00
IUUC-Tgu-116477	Taeniopygia guttata	63.46	6.00e-165	573.00
IUUC-Tru-117872	Takifugu rubripes	62.89	2.00e-164	572.00
IUUC-Tni-120754	Tetraodon nigroviridis	61.52	1.00e-166	579.00
IUUC-Tvi-122391	Trichoderma virens	37.61	2.00e-84	306.00
IUUC-Tbe-127693	Tupaia belangeri	56.97	9.00e-118	416.00
IUUC-Ttr-129188	Tursiops truncatus	62.27	1.00e-168	585.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence